Intracellular degradation of secretion defect-type mutants of antithrombin is inhibited by proteasomal inhibitors

FEBS Letters

Volumn 412, Issue 1, 1997, Pages 65-69

  Tokunaga, Fuminori ^a   Shirotani, Hiroko ^a   Hara, Kazuya ^a   Kozuki, Daisuke ^a   Omura, Satoshi ^b   Koide, Takehiko ^a  

^a UNIVERSITY OF HYOGO   (Japan)

^b KITASATO INSTITUTE   (Japan)

Author keywords

Antithrombin; Endoplastic reticulum associated degradation; Lactacystin; Proteasome; Quality control

Indexed keywords

ANTITHROMBIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; BREFELDIN A; CARBOBENZOXYLEUCYLLEUCYLNORVALINAL; ENDOGLYCOSIDASE H; GLUTAMIC ACID; LACTACYSTIN; MUTANT PROTEIN; PROTEASOME; PROTEINASE INHIBITOR; RADIOISOTOPE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTITHROMBIN DEFICIENCY; ARTICLE; CELL STRAIN BHK; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE DELETION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUALITY CONTROL; SECRETION; STOP CODON;

ACETYLCYSTEINE; ANIMALS; ANTITHROMBIN III; BREFELDIN A; CELL LINE; CRICETINAE; CYCLOPENTANES; CYSTEINE ENDOPEPTIDASES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FLUORESCENT ANTIBODY TECHNIQUE; GOLGI APPARATUS; HUMANS; KIDNEY; LEUPEPTINS; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SYNTHESIS INHIBITORS; TRANSFECTION;

ANIMALIA;

EID: 0030858241     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00745-X     Document Type: Article

References (29)

1. Travis, J. and Salvesen, G.S. (1983) Annu. Rev. Biochem. 52, 655-709.
2. I. Björk, and Å. Danielsson, in: A.J. Barrett, and G. Salvessen (Eds.), Elsevier, Amsterdam, 1986, pp. 489-513.
3. Chandra, T., Stackhouse, R., Kidd, V.J. and Woo, S.L.C. (1983) Proc. Natl. Acad. Sci. USA 80, 1845-1848.
4. Thaler, E. and Lechner, K. (1981) Clin. Hematol. 10, 369-390.
5. Lane, D.A., Olds, R.J., Boisclair, M., Chowdhury, V., Thein, S.L., Cooper, D.N., Blajchman, M., Perry, D., Emmerich, J. and Aiach, M. (1993) Thromb. Haemostas. 70, 361-369.
6. Lane, D.A., Bayston, T., Olds, R.J., Fitches, A.C., Cooper, D.N., Millar, D.S., Jochmans, K., Perry, D.J., Okajima, K. and Emmerich, J. (1997) Thromb. Haemostas. 77, 197-211.
7. Chowdhury, V., Olds, R.J., Lane, D.A., Conard, J., Pabinger, I., Ryan, K., Bauer, K., Bhavani, M., Abildgaard, U., Finazzi, G., Castaman, G., Mannucci, P.M. and Thein, S.L. (1993) Br. J. Haematol. 84, 656-661.
8. Brodlbeck, B.M. and Brown, J.L. (1992) J. Biol. Chem. 267, 294-297.
9. Koide, T. (1979) J. Biochem. (Tokyo) 86, 1841-1850.
10. Omura, S., Fujimoto, T., Otoguro, K., Matsuzaki, K., Moriguchi, R., Tanaka, H. and Sasaki, Y. (1991) J. Antibiot. 44, 113-116.
11. Chen, C. and Okayama, H. (1987) Mol. Cell. Biol. 7, 2745-2752.
12. Tokunaga, F., Wakabayashi, S. and Koide, T. (1995) Biochemistry 34, 1163-1170.
13. Tokunaga, F., Tsukamoto, T. and Koide, T. (1996) J. Biochem. (Tokyo) 120, 360-368.
14. Misumi, Y., Misumi, Y., Miki, K., Takatsuki, A., Tamura, G. and Ikehara, Y. (1986) J. Biol. Chem. 261, 11398-11403.
15. O. Coux, K. Tanaka, and A.L. Goldberg, Annu. Rev. Biochem. (1996) 801-847.
16. Fenteany, G., Standaert, R.F., Lane, W.S., Choi, S., Corey, C.E.J. and Schreiber, S.L. (1995) Science 268, 726-731.
17. Urade, R. and Kito, M. (1992) FEBS Lett. 312, 83-86.
18. Urade, R., Takenaka, Y. and Kito, M. (1993) J. Biol. Chem. 268, 22004-22009.
19. Seglen, P.O., Grinde, B. and Solheim, A.E. (1979) Eur. J. Biochem. 95, 215-225.
20. Klausner, R.D. and Sitia, R. (1990) Cell 62, 611-616.
21. Fra, A.M. and Sitia, R. (1993) Sub.-Cell. Biochem. 21, 143-168.
22. Inoue, S., Bar-Nun, S., Roitelman, J. and Simoni, R.D. (1991) J. Biol. Chem. 266, 13311-13317.
23. Sakata, N., Wu, X., Dixon, J.L. and Ginsberg, H.N. (1993) J. Biol. Chem. 268, 22967-22970.
24. Amitay, R., Shachar, .I, Rabinovich, E., Haimovich, J. and BarNun, S. (1992) J. Biol. Chem. 267, 20694-20700.
25. Gardner, A.M., Aviel, S. and Argon, Y. (1993) J. Biol. Chem. 268, 25940-25947.
26. Ward, C.L., Omura, S. and Kopito, R.R. (1995) Cell 83, 121-127.
27. Jensen, T.J., Loo, M.A., Pind, S., Williams, D.B., Goldberg, A.L. and Riordan, J.R. (1995) Cell 83, 129-135.
28. Wiertz, E.J.H.J., Jones, T.R., Sun, L., Bogyo, M., Geuze, H.J. and Ploegh, H.L. (1996) Cell 84, 769-779.
29. Oda, K., Ikehara, Y. and Omura, S. (1996) Biochem. Biophys. Res. Commun. 219, 800-805.