메뉴 건너뛰기




Volumn 75, Issue 9, 1997, Pages 637-644

Recent progress in studies of neurotrophic factors and their clinical implications

Author keywords

Brain derived neurotrophic factor; C ret tyrosine kinase; Dopaminergic neurons; Enteric nervous system; Gene knockout; Gila derived neurotrophic factor; Hirschsprung's disease; Kidney organogenesis; Long term potentiation; Trk receptor

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIC FACTOR;

EID: 0030851061     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001090050147     Document Type: Review
Times cited : (37)

References (91)
  • 1
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Barde Y (1989) Trophic factors and neuronal survival. Neuron 2:1525-1534
    • (1989) Neuron , vol.2 , pp. 1525-1534
    • Barde, Y.1
  • 2
    • 0028238769 scopus 로고
    • Functions of neurotrophins during nervous system development: What the knockouts are teaching us
    • Snider WD (1994) Functions of neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-636
    • (1994) Cell , vol.77 , pp. 627-636
    • Snider, W.D.1
  • 3
    • 0027195615 scopus 로고
    • The neurotrophic factor concept: A reexamination
    • Korsching S (1993) The neurotrophic factor concept: a reexamination. J Neurosci 13:2739-2748
    • (1993) J Neurosci , vol.13 , pp. 2739-2748
    • Korsching, S.1
  • 6
    • 15844394982 scopus 로고    scopus 로고
    • Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons
    • Pennica D, Arce V, Swanson TA, Vejsada R, Pollock RA, Armanini M, Dudley K (1996) Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons. Neuron 17:63-74
    • (1996) Neuron , vol.17 , pp. 63-74
    • Pennica, D.1    Arce, V.2    Swanson, T.A.3    Vejsada, R.4    Pollock, R.A.5    Armanini, M.6    Dudley, K.7
  • 7
    • 0028149838 scopus 로고
    • The tripartite CNTF receptor complex: Activation and signaling involves components shared with other cytokines
    • Stahl N, Yancopoulos GD (1994) The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines. J Neurobiol 25:1454-1466
    • (1994) J Neurobiol , vol.25 , pp. 1454-1466
    • Stahl, N.1    Yancopoulos, G.D.2
  • 8
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for mid-brain dopaminergic neurons
    • Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line-derived neurotrophic factor for mid-brain dopaminergic neurons. Science 260:1130-1132
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 12
    • 15844365303 scopus 로고    scopus 로고
    • GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF
    • Jing S, Wen D, Yu Y, Holst PL, Luo Y, Fang M, Tamir R (1996) GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF. Cell 85:1113-1124
    • (1996) Cell , vol.85 , pp. 1113-1124
    • Jing, S.1    Wen, D.2    Yu, Y.3    Holst, P.L.4    Luo, Y.5    Fang, M.6    Tamir, R.7
  • 13
    • 0027972153 scopus 로고
    • Neurotrophic factor therapy for nervous system degenerative diseases
    • Hefti F (1994) Neurotrophic factor therapy for nervous system degenerative diseases. J Neurobiol 25:1418-1435
    • (1994) J Neurobiol , vol.25 , pp. 1418-1435
    • Hefti, F.1
  • 14
    • 0028795044 scopus 로고
    • Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
    • Beck KD, Valverde J, Alexi T, Poulsen K, Moffat B, Vandlen RA, Rosenthal A (1995) Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373:339-341
    • (1995) Nature , vol.373 , pp. 339-341
    • Beck, K.D.1    Valverde, J.2    Alexi, T.3    Poulsen, K.4    Moffat, B.5    Vandlen, R.A.6    Rosenthal, A.7
  • 17
    • 0025877704 scopus 로고
    • The changing scene of neurotrophic factors
    • Thoenen H (1991) The changing scene of neurotrophic factors. Trends Neurosci 14:165-170
    • (1991) Trends Neurosci , vol.14 , pp. 165-170
    • Thoenen, H.1
  • 18
    • 0029063836 scopus 로고
    • Trophic factor response to neuronal stimuli or injury
    • Isackson PJ (1995) Trophic factor response to neuronal stimuli or injury. Curr Opin Neurobiol 5:350-357
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 350-357
    • Isackson, P.J.1
  • 19
    • 0028866230 scopus 로고
    • Neurotrophins and neuronal plasticity
    • Thoenen H (1995) Neurotrophins and neuronal plasticity. Science 270:593-596
    • (1995) Science , vol.270 , pp. 593-596
    • Thoenen, H.1
  • 20
    • 0025084077 scopus 로고
    • Activity-dependent regulation of BDNF and NGF mRNA in the rat hippocampus is mediated by non-NMDA glutamate receptors
    • Zafra F, Hengerer B, Leibrock J, Thoenen H, Lindholm D (1990) Activity-dependent regulation of BDNF and NGF mRNA in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 9:3545-3550
    • (1990) EMBO J , vol.9 , pp. 3545-3550
    • Zafra, F.1    Hengerer, B.2    Leibrock, J.3    Thoenen, H.4    Lindholm, D.5
  • 21
    • 0025912871 scopus 로고
    • Depolarizing stimuli regulate NGF mRNA expression in cultured hippocampal neurons
    • Lu B, Yokoyama M, Dreyfus CF, Black IB (1991) Depolarizing stimuli regulate NGF mRNA expression in cultured hippocampal neurons. Proc Natl Acad Sci USA 88:6289-6292
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6289-6292
    • Lu, B.1    Yokoyama, M.2    Dreyfus, C.F.3    Black, I.B.4
  • 22
    • 0025889012 scopus 로고
    • Interplay between glutamate and γ-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons
    • Zafra F, Castren F, Thoenen H, Lindholm D (1991) Interplay between glutamate and γ-aminobutyric acid transmitter systems in the physiological regulation of brain-derived neurotrophic factor and nerve growth factor synthesis in hippocampal neurons. Proc Natl Acad Sci USA 88: 10037-10041
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10037-10041
    • Zafra, F.1    Castren, F.2    Thoenen, H.3    Lindholm, D.4
  • 23
    • 0026459311 scopus 로고
    • Regulation of Brain-derived neurtorphic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes
    • Zafra F, Lindholm D, Castren E, Hartikka J, Thoenen H (1992) Regulation of Brain-derived neurtorphic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes. J Neurosci 12:4793-4799
    • (1992) J Neurosci , vol.12 , pp. 4793-4799
    • Zafra, F.1    Lindholm, D.2    Castren, E.3    Hartikka, J.4    Thoenen, H.5
  • 24
    • 0026648859 scopus 로고
    • Light regulates expression of brain-derived neurotrophic factor mRNA in the rat visual cortex
    • Castren E, Zafra F, Theonen H, Lindholm D (1992) Light regulates expression of brain-derived neurotrophic factor mRNA in the rat visual cortex. Proc Natl Acad Sci USA 89:9444-9448
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9444-9448
    • Castren, E.1    Zafra, F.2    Theonen, H.3    Lindholm, D.4
  • 25
    • 0024386959 scopus 로고
    • Limbic seizures increase neuronal production of messenger RNA for nerve growth factor
    • Gall CM, Isackson PJ (1989) Limbic seizures increase neuronal production of messenger RNA for nerve growth factor. Science 245:758-761
    • (1989) Science , vol.245 , pp. 758-761
    • Gall, C.M.1    Isackson, P.J.2
  • 26
    • 0025883295 scopus 로고
    • BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF
    • Isackson PJ, Huntsman MM, Murray KD, Gall. CM (1991) BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF. Neuron 6:937-948
    • (1991) Neuron , vol.6 , pp. 937-948
    • Isackson, P.J.1    Huntsman, M.M.2    Murray, K.D.3    Gall, C.M.4
  • 27
    • 0025766899 scopus 로고
    • Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis
    • Ernfors P, Bengzon J, Kokaia Z, Persson H, Lindvall O (1991) Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis. Neuron 7:165-176
    • (1991) Neuron , vol.7 , pp. 165-176
    • Ernfors, P.1    Bengzon, J.2    Kokaia, Z.3    Persson, H.4    Lindvall, O.5
  • 30
    • 0029086156 scopus 로고
    • Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat
    • Larmet Y, Reibel S, Carnahan J, Nawa H, Marescaux C, Depaulis A (1995) Protective effects of brain-derived neurotrophic factor on the development of hippocampal kindling in the rat. Neuroreport 6:1937-41
    • (1995) Neuroreport , vol.6 , pp. 1937-1941
    • Larmet, Y.1    Reibel, S.2    Carnahan, J.3    Nawa, H.4    Marescaux, C.5    Depaulis, A.6
  • 31
    • 0026875582 scopus 로고
    • Signal transduction and regulation of neurotrophins
    • Lo DC (1992) Signal transduction and regulation of neurotrophins. Curr Opin Neurobiol 2:336-340
    • (1992) Curr Opin Neurobiol , vol.2 , pp. 336-340
    • Lo, D.C.1
  • 32
    • 0027281189 scopus 로고
    • Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF
    • Lohof AM, Ip NY, Poo MM (1993) Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature 363:350-353
    • (1993) Nature , vol.363 , pp. 350-353
    • Lohof, A.M.1    Ip, N.Y.2    Poo, M.M.3
  • 33
    • 0028903917 scopus 로고
    • Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling
    • Stoop R, Poo MM (1995) Potentiation of transmitter release by ciliary neurotrophic factor requires somatic signaling. Science 267:695-699
    • (1995) Science , vol.267 , pp. 695-699
    • Stoop, R.1    Poo, M.M.2
  • 34
    • 0029999022 scopus 로고    scopus 로고
    • Synaptic modulation by neurotrophic factors: Differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor
    • Stoop R, Poo MM (1996) Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J Neurosci 16:3256-3264
    • (1996) J Neurosci , vol.16 , pp. 3256-3264
    • Stoop, R.1    Poo, M.M.2
  • 35
    • 0028152869 scopus 로고
    • Neurotrophin 3 potentiates neuronal activity and inhibits γ-aminobutyrateric synaptic transmission in cortical neurons
    • Kim HG, Wang T, Olafsson P, Lu B (1994) Neurotrophin 3 potentiates neuronal activity and inhibits γ-aminobutyrateric synaptic transmission in cortical neurons. Proc Natl Acad Sci USA 91:12341-12345
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12341-12345
    • Kim, H.G.1    Wang, T.2    Olafsson, P.3    Lu, B.4
  • 36
    • 0028588699 scopus 로고
    • Short-term modulation of glutamatergic synapses in adult rat hippocampus by NGF
    • Knipper M, Leung LS, Zhao D, Rylett RJ (1994) Short-term modulation of glutamatergic synapses in adult rat hippocampus by NGF. Neuroreport 5:2433-2436
    • (1994) Neuroreport , vol.5 , pp. 2433-2436
    • Knipper, M.1    Leung, L.S.2    Zhao, D.3    Rylett, R.J.4
  • 37
    • 0028590148 scopus 로고
    • BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones
    • Lessmann V, Gottmann K, Heumann R (1994) BDNF and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones. Neuroreport 6:21-25
    • (1994) Neuroreport , vol.6 , pp. 21-25
    • Lessmann, V.1    Gottmann, K.2    Heumann, R.3
  • 38
    • 0029099174 scopus 로고
    • Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors
    • Levine ES, Dreyfus CF, Black IB, Plummer MR (1995) Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors. Proc Natl Acad Sci USA 92:8074-8077
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8074-8077
    • Levine, E.S.1    Dreyfus, C.F.2    Black, I.B.3    Plummer, M.R.4
  • 39
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss TVP, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361: 31-39
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 40
    • 0027485836 scopus 로고
    • NMDA-receptor-dependent synaptic plasticity: Multiple forms and mechanisms
    • Malenka RC, Nicoll RA (1993) NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms. Trends Neurosci 16:521-527
    • (1993) Trends Neurosci , vol.16 , pp. 521-527
    • Malenka, R.C.1    Nicoll, R.A.2
  • 41
    • 0023908218 scopus 로고
    • Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP-phnomena in the CA-region in vitro
    • Frey U, Krug M, Reymann KG, Mathies H (1984) Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP-phnomena in the CA-region in vitro. Brain Res 452:57-65
    • (1984) Brain Res , vol.452 , pp. 57-65
    • Frey, U.1    Krug, M.2    Reymann, K.G.3    Mathies, H.4
  • 42
    • 0028038057 scopus 로고
    • Requirement of a critical period of transcription for induction of a later phase of LTP
    • Nguyen PT, Abel T, Kendal ER (1994) Requirement of a critical period of transcription for induction of a later phase of LTP. Science 265:1104-1107
    • (1994) Science , vol.265 , pp. 1104-1107
    • Nguyen, P.T.1    Abel, T.2    Kendal, E.R.3
  • 43
    • 0021523971 scopus 로고
    • Protein synthesis and memory: A review
    • Davies H, Squire L (1984) Protein synthesis and memory: a review. Psychol Bull 96:518-599
    • (1984) Psychol Bull , vol.96 , pp. 518-599
    • Davies, H.1    Squire, L.2
  • 44
    • 0027075042 scopus 로고
    • Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
    • Patterson S, Grover LM, Schwartzkroin PA, Bothwell M (1992) Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs. Neuron 9:1081-1088
    • (1992) Neuron , vol.9 , pp. 1081-1088
    • Patterson, S.1    Grover, L.M.2    Schwartzkroin, P.A.3    Bothwell, M.4
  • 46
    • 0029987847 scopus 로고    scopus 로고
    • Unilateral LTP triggers bilateral increases in hippocampal neurotrophin and trk receptor mRNA expression in behaving rats: Evidence for interhemispheric communication
    • Bramham CR, Southard T, Sarvey J, Herkenham M, Brady LS (1996) Unilateral LTP triggers bilateral increases in hippocampal neurotrophin and trk receptor mRNA expression in behaving rats: evidence for interhemispheric communication. J Comp Neurol 368:371-382
    • (1996) J Comp Neurol , vol.368 , pp. 371-382
    • Bramham, C.R.1    Southard, T.2    Sarvey, J.3    Herkenham, M.4    Brady, L.S.5
  • 47
    • 0029021177 scopus 로고
    • Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor
    • Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T (1995) Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc Natl Acad Sci USA 92:8856-8860
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8856-8860
    • Korte, M.1    Carroll, P.2    Wolf, E.3    Brem, G.4    Thoenen, H.5    Bonhoeffer, T.6
  • 48
    • 0030176079 scopus 로고    scopus 로고
    • Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
    • Patterson SL, Abel T, Deuel TA, Martin KC, Rose JC, Kandel ER (1996) Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice. Neuron 16:1137-1145
    • (1996) Neuron , vol.16 , pp. 1137-1145
    • Patterson, S.L.1    Abel, T.2    Deuel, T.A.3    Martin, K.C.4    Rose, J.C.5    Kandel, E.R.6
  • 49
    • 0029910815 scopus 로고    scopus 로고
    • Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice
    • Korte M, Griesbeck O, Gravel C, Carroll P, V. Staiger, Thoenen H, Bonhoeffer T (1996) Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice. Proc Natl Acad Sci USA 93:12547-12552
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12547-12552
    • Korte, M.1    Griesbeck, O.2    Gravel, C.3    Carroll, P.4    Staiger, V.5    Thoenen, H.6    Bonhoeffer, T.7
  • 51
    • 0025817447 scopus 로고
    • Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain
    • Friedman WJ, Olson L, Persson H (1991) Cells that express brain-derived neurotrophic factor mRNA in the developing postnatal rat brain. Eur J Neurosci 3:688-697
    • (1991) Eur J Neurosci , vol.3 , pp. 688-697
    • Friedman, W.J.1    Olson, L.2    Persson, H.3
  • 52
    • 0027502622 scopus 로고
    • Expression of members of the trk family in the developing postnatal rat brain
    • Ringstedt T, Kagercrabtz H, Persson H (1993) Expression of members of the trk family in the developing postnatal rat brain. Dev Brain Res 72:119-131
    • (1993) Dev Brain Res , vol.72 , pp. 119-131
    • Ringstedt, T.1    Kagercrabtz, H.2    Persson, H.3
  • 53
    • 0027184365 scopus 로고
    • Transient elevation in catalytic trkB mRNA during postnatal development of the rat brain
    • Dugich-Djordjevic MM, Ohsawa F, Hefti F (1993) Transient elevation in catalytic trkB mRNA during postnatal development of the rat brain. NeuroReport 4:1091-1094
    • (1993) NeuroReport , vol.4 , pp. 1091-1094
    • Dugich-Djordjevic, M.M.1    Ohsawa, F.2    Hefti, F.3
  • 54
    • 0021286941 scopus 로고
    • Developmental onset of long-term potentiation in area CA1 of the rat hippocampus
    • Harris KM, Teyler TJ (1984) Developmental onset of long-term potentiation in area CA1 of the rat hippocampus. J Physiol 346:27-48
    • (1984) J Physiol , vol.346 , pp. 27-48
    • Harris, K.M.1    Teyler, T.J.2
  • 55
    • 0024418402 scopus 로고
    • Developmental changes in synaptic properties in hippocampus of neonatal rats
    • Muller D, Oliver M, Lynch G (1989) Developmental changes in synaptic properties in hippocampus of neonatal rats. Dev Brain Res 49:105-114
    • (1989) Dev Brain Res , vol.49 , pp. 105-114
    • Muller, D.1    Oliver, M.2    Lynch, G.3
  • 56
    • 0027359050 scopus 로고
    • Stereotypical changes in the pattern and duration of long-term potentiation expressed at postnatal day 11 and 15 in the rat hippocampus
    • Jackson PS, Suppes T, Harris KM (1993) Stereotypical changes in the pattern and duration of long-term potentiation expressed at postnatal day 11 and 15 in the rat hippocampus. J Neurophysiol 70:1412-1419
    • (1993) J Neurophysiol , vol.70 , pp. 1412-1419
    • Jackson, P.S.1    Suppes, T.2    Harris, K.M.3
  • 57
    • 0029970008 scopus 로고    scopus 로고
    • Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus
    • Figurov A, Pozzo ML, Olafsson P, Wang T, Lu B (1996) Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus. Nature 381: 706-709
    • (1996) Nature , vol.381 , pp. 706-709
    • Figurov, A.1    Pozzo, M.L.2    Olafsson, P.3    Wang, T.4    Lu, B.5
  • 59
    • 0028896736 scopus 로고
    • Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomie ganglia
    • Ebendal T, Tomac A, Hoffer BJ, Oison L (1995) Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomie ganglia. J Neurosci Res 40:276-284
    • (1995) J Neurosci Res , vol.40 , pp. 276-284
    • Ebendal, T.1    Tomac, A.2    Hoffer, B.J.3    Oison, L.4
  • 60
    • 0029007011 scopus 로고
    • Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons
    • Trupp M, Ryden M, Jornvall H, Funakoshi H, Timmusk T, Arenas E, Ibanez CF (1995) Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J Cell Biol 130:137-148
    • (1995) J Cell Biol , vol.130 , pp. 137-148
    • Trupp, M.1    Ryden, M.2    Jornvall, H.3    Funakoshi, H.4    Timmusk, T.5    Arenas, E.6    Ibanez, C.F.7
  • 61
    • 0028884522 scopus 로고
    • GDNF is an age-specific survival factor for sensory and autonomie neurons
    • Buj-Bello A, Buchman VL, Horton A, Rosenthal A, Davies AM (1995) GDNF is an age-specific survival factor for sensory and autonomie neurons. Neuron 15:821-828
    • (1995) Neuron , vol.15 , pp. 821-828
    • Buj-Bello, A.1    Buchman, V.L.2    Horton, A.3    Rosenthal, A.4    Davies, A.M.5
  • 62
    • 0028109526 scopus 로고
    • Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
    • Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin LF (1994) Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neurosci Lett 182:107-111
    • (1994) Neurosci Lett , vol.182 , pp. 107-111
    • Hoffer, B.J.1    Hoffman, A.2    Bowenkamp, K.3    Huettl, P.4    Hudson, J.5    Martin, D.6    Lin, L.F.7
  • 64
    • 0028986656 scopus 로고
    • TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity
    • Krieglstein K, Suter CC, Fischer WH, Unsicker K (1995) TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity. EMBO J 14:736-742
    • (1995) EMBO J , vol.14 , pp. 736-742
    • Krieglstein, K.1    Suter, C.C.2    Fischer, W.H.3    Unsicker, K.4
  • 65
    • 0028874203 scopus 로고
    • GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo
    • Kearns CM, Gash DM (1995) GDNF protects nigral dopamine neurons against 6-hydroxydopamine in vivo. Brain Res 672: 104-111
    • (1995) Brain Res , vol.672 , pp. 104-111
    • Kearns, C.M.1    Gash, D.M.2
  • 66
    • 0028917168 scopus 로고
    • Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and parkinsonian symptoms
    • Lindner MD, Winn SR, Baetge EE, Hammang JP, Gentile FT, Doherty E, McDermott PE (1995) Implantation of encapsulated catecholamine and GDNF-producing cells in rats with unilateral dopamine depletions and parkinsonian symptoms. Exp Neurol 132:62-76
    • (1995) Exp Neurol , vol.132 , pp. 62-76
    • Lindner, M.D.1    Winn, S.R.2    Baetge, E.E.3    Hammang, J.P.4    Gentile, F.T.5    Doherty, E.6    McDermott, P.E.7
  • 67
    • 0029047329 scopus 로고
    • Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion
    • Sauer H, Rosenblad C, Bjorklund A (1995) Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion. Proc Natl Acad Sci USA 92:8935-8939
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8935-8939
    • Sauer, H.1    Rosenblad, C.2    Bjorklund, A.3
  • 68
    • 0030031116 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium
    • Hou JG, Lin LF, Mytilineou C (1996) Glial cell line-derived neurotrophic factor exerts neurotrophic effects on dopaminergic neurons in vitro and promotes their survival and regrowth after damage by 1-methyl-4-phenylpyridinium. J Neurochem 66:74-82
    • (1996) J Neurochem , vol.66 , pp. 74-82
    • Hou, J.G.1    Lin, L.F.2    Mytilineou, C.3
  • 69
    • 0028597994 scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones
    • Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P (1994) Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport 6:113-118
    • (1994) Neuroreport , vol.6 , pp. 113-118
    • Zurn, A.D.1    Baetge, E.E.2    Hammang, J.P.3    Tan, S.A.4    Aebischer, P.5
  • 71
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan Q, Matheson C, Lopez OT (1995) In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 74
  • 77
    • 0024315501 scopus 로고
    • Developmental regulated conversion of mesenchyme to epithelium
    • Ekblom P (1989) Developmental regulated conversion of mesenchyme to epithelium. FASEB J 3:2141-2150
    • (1989) FASEB J , vol.3 , pp. 2141-2150
    • Ekblom, P.1
  • 78
    • 0028604499 scopus 로고
    • GDNF is expressed in two forms in many tissues outside the CNS
    • Suter CC, Unsicker K (1994) GDNF is expressed in two forms in many tissues outside the CNS. Neuroreport 5:2486-2488
    • (1994) Neuroreport , vol.5 , pp. 2486-2488
    • Suter, C.C.1    Unsicker, K.2
  • 79
    • 0029007011 scopus 로고
    • Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian perioheral neurons
    • Trupp M, Ryden M, Jornvall H, Funakoshi H, Timmusk T, Arenas E, Ibanez C (1995) Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian perioheral neurons. J Cell Biol 130:137-148
    • (1995) J Cell Biol , vol.130 , pp. 137-148
    • Trupp, M.1    Ryden, M.2    Jornvall, H.3    Funakoshi, H.4    Timmusk, T.5    Arenas, E.6    Ibanez, C.7
  • 80
    • 0030024846 scopus 로고    scopus 로고
    • Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions
    • Hellmich HL, Kos L, Cho ES, Mahon KA, Zimmer A (1996) Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech Dev 54:95-105
    • (1996) Mech Dev , vol.54 , pp. 95-105
    • Hellmich, H.L.1    Kos, L.2    Cho, E.S.3    Mahon, K.A.4    Zimmer, A.5
  • 81
    • 0030007849 scopus 로고    scopus 로고
    • Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization
    • Suvanto P, Hiltunen JO, Arumae U, Moshnyakov M, Sariola H, Sainio K, Saarma M (1996) Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridization. Eur J Neurosci 18:101-107
    • (1996) Eur J Neurosci , vol.18 , pp. 101-107
    • Suvanto, P.1    Hiltunen, J.O.2    Arumae, U.3    Moshnyakov, M.4    Sariola, H.5    Sainio, K.6    Saarma, M.7
  • 83
    • 0016488934 scopus 로고
    • Animal model of human disease. Hischsprung's disease, aganglionic or hypoganglionic megacolon; animal model: Aganglionic megacolon in piebald and spotted mutant mouse strains
    • Bolande RP (1975) Animal model of human disease. Hischsprung's disease, aganglionic or hypoganglionic megacolon; animal model: aganglionic megacolon in piebald and spotted mutant mouse strains. Am J Path 79:189-192
    • (1975) Am J Path , vol.79 , pp. 189-192
    • Bolande, R.P.1
  • 84
    • 0022437326 scopus 로고
    • Hirschprung's disease: A historical review
    • Case D (1986) Hirschprung's disease: a historical review. Prog Pediatr Surg 20:199-214
    • (1986) Prog Pediatr Surg , vol.20 , pp. 199-214
    • Case, D.1
  • 85
    • 0028120882 scopus 로고
    • Point mutations affecting the tyrosine kinase domain of the RET protooncogene in Hirschsprung's disease
    • Romeo G, Ronchetto P, Luo Y, Barone V, Seri M, Ceccherini I, Pacini B (1994) Point mutations affecting the tyrosine kinase domain of the RET protooncogene in Hirschsprung's disease. Nature 367:377-378
    • (1994) Nature , vol.367 , pp. 377-378
    • Romeo, G.1    Ronchetto, P.2    Luo, Y.3    Barone, V.4    Seri, M.5    Ceccherini, I.6    Pacini, B.7
  • 87
    • 0028174023 scopus 로고
    • Defects in the kidney and enteric nervous system of mice lacking the lyrosine kinase receptor Ret
    • Schuchardt A, D'Agati V, Larsson-Blomberg L, Costantini F, Pachnis V (1994) Defects in the kidney and enteric nervous system of mice lacking the lyrosine kinase receptor Ret. Nature 367:380-383
    • (1994) Nature , vol.367 , pp. 380-383
    • Schuchardt, A.1    D'Agati, V.2    Larsson-Blomberg, L.3    Costantini, F.4    Pachnis, V.5
  • 88
    • 0024208663 scopus 로고
    • Cloning and expression of the ret protooncogene encoding a tyrosine kinase with two potential transmembrane domains
    • Takahashi M, Buma Y, Iwamoto T, Inaguma Y, Ikeka H, Hiai H (1988) Cloning and expression of the ret protooncogene encoding a tyrosine kinase with two potential transmembrane domains. Oncogene 3:571-578
    • (1988) Oncogene , vol.3 , pp. 571-578
    • Takahashi, M.1    Buma, Y.2    Iwamoto, T.3    Inaguma, Y.4    Ikeka, H.5    Hiai, H.6
  • 89
    • 0027374562 scopus 로고
    • Expression of the c-ret proto-oncogene during mouse embryogenesis
    • Pachnis V, Mankoo B, Constantini F (1993) Expression of the c-ret proto-oncogene during mouse embryogenesis. Development 119:1005-1007
    • (1993) Development , vol.119 , pp. 1005-1007
    • Pachnis, V.1    Mankoo, B.2    Constantini, F.3
  • 90
    • 0027729156 scopus 로고
    • The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease
    • Lindsay RM, Altar CA, Cedarbaum JM, Hyman C, Wiegand SJ (1993) The therapeutic potential of neurotrophic factors in the treatment of Parkinson's disease. Exp Neurol 124:103-118
    • (1993) Exp Neurol , vol.124 , pp. 103-118
    • Lindsay, R.M.1    Altar, C.A.2    Cedarbaum, J.M.3    Hyman, C.4    Wiegand, S.J.5
  • 91
    • 0027756168 scopus 로고
    • Trophic support of motoneurons: Physiological pathophysiological, and therapeutic implications
    • Thoenen H, Hughes RA, Sendtner M (1993) Trophic support of motoneurons: physiological pathophysiological, and therapeutic implications. Exp Neurol 124:47-55
    • (1993) Exp Neurol , vol.124 , pp. 47-55
    • Thoenen, H.1    Hughes, R.A.2    Sendtner, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.