DNA damage, repair and chromosonal damage

International Journal of Radiation Biology

Volumn 71, Issue 6, 1997, Pages 675-680

  Bryant, P E ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL CYCLE; CHROMATID; CHROMOSOME ABERRATION; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; METAPHASE; PRIORITY JOURNAL; RADIOSENSITIVITY;

ANIMALS; CHO CELLS; CHROMOSOME ABERRATIONS; CHROMOSOMES; CRICETINAE; DNA DAMAGE; DNA REPAIR; TIME FACTORS; VIDARABINE;

ATAXIA; ATAXIA TELANGIECTASIA;

EID: 0030850703     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530097143680     Document Type: Article

References (47)

1. BIEDERMANN, K., SUN, J., GIACCIA, A., TASTO, L. and BROWN, J. M., 1991, The scid mutation in mice confers hypersensitivity to ionising radiation and a deficiency in DNA double strand break repair. Proceedings of the National Academy of Sciences, USA, 88, 1394-1397.
2. BLÖCHER, D., SIGUT, D. and HANNAN, M. A., 1991, Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate γ-irradiation as assayed by pulsed field gel electrophoresis. International Journal of Radiation Biology, 60, 791-802.
3. BLUNT, T., FINNE, N. J., TACCIOLI, G. E., SMITH, G. C. M., DEMENGEOT, J., GOTTLEIB, T. M., MIZUTA, R., VARGHESE, A.J., ALT, F. W., JEGGO, P. A. and JACKSON, S. P., 1995, Defective DNA-dependent protein kinase activity is linked to V(D) recombination and DNA repair defects associated with the murine seid mutation. Cell, 80, 813-823.
4. BRYANT, P. E., 1984, Enzymatic restriction of mammalian cell DNA using Pvu II and BamH I: evidence for the double-strand break origin of chromosomal aberrations. International Journal of Radiation Biology, 46, 55-60.
5. BRYANT, P. E. and BLÖCHER, D., 1982, The effects of 9-β-D-arabinofuranosyladenine on the repair of DNA strand breaks in X-irradiated Ehrlich ascites tumour cells. International Journal of Radiation Biology, 42, 385-394.
6. BRYANT, P. E. and SLIJEPCEVIC, P., 1993, G2 chromatid aberrations: Kinetics and possible mechanisms. Environmental and Molecular Mutagenesis, 22, 250-256.
7. CHAMPION, A. R., HANSON, J. A., COURT, J. B. and VENABLES, S. E., 1995, The micronucleus assay: an evaluation of its use in determining radiosensitivity in vitro. Mutagenesis, 10, 203-208.
8. CHENG, X., PANTELIAS, G. E., OKAYASU, R., CHEONG, N. and ILIAKIS, G., 1993, Mitosis-promoting factor activity of inducer mitotic cells may affect radiation yield of interphase chromosome breaks in the premature chromosome condensation assay. Cancer Research, 53, 5592-5596.
9. COCO-MARTIN, J. M., SMEETS, M. F. M. A., POGGENSEE, M., MOOREN, E., HOFLAND, I., VAN DEN BRUG, M., OTTENHEIM, C., BARTELINK, H. and BEGG, A. C., 1994, Use of fluorescence in situ hybridisation to measure chromosome aberrations as a predictor of radiosensitivity in human tumour cells. International Journal of Radiation Biology, 66, 297-307.
10. CORNFORTH, M. and BEDFORD, J. S., 1985, On the nature of the defect in cells from individuals with ataxia telangiectasia. Science, 227, 1589-1591.
11. DARROUDI, F. and NATARAJAN, A. T., 1989, Cytogenetical characterisation of Chinese hamster ovary X-ray sensitive mutant cells xrs5 and xrs6: VII. Complementation analysis of X-irradiated wild-type CHO-K1 and xrs mutant cells using the premature chromosome condensation technique. Mutation Research, 213, 249-255.
12. FENNECH, M. and MORLEY, A. A., 1985, Measurement of micronuclei in lymphocytes. Mutation Research, 147, 29-36.
13. FRANKENBERG, D., FRANKENBERG-SCHWAGER, M. and HARBICH, R., 1984, Interpretation of the shape of survival curves in terms of induction and repair/misrepair of DNA double-strand breaks. British Journal of Cancer, 49 (Suppl), 233-238.
14. FRANKENBERG-SCHWAGER, M. and FRANKENBERG, D., 1990, DNA double-strand breaks: their repair and relationship to cell killing in yeast. International Journal of Radiation Biology, 58, 569-575.
15. HEDDLE, J. A. and BODYCOTE, D. J., 1970, On the formation of chromosomal aberrations. Mutation Research, 9, 117-126.
16. HEDDLE, J. A., WHISSELL, D. and BODYCOTE, D. J., 1969, Changes in chromosome structure induced by radiations: A test of two chief hypotheses. Nature (London), 221, 1158-1160.
17. HO, K., 1985, Induction of double-strand breaks by X-rays in a radiosensitive strain of the yeast Saccharomyces cerevisae. Mutation Research, 30, 327-334.
18. ILIAKIS, G., OKAYASU, R. and SEANER, R., 1988, Radiosensitive xrs5 and parental CHO cells show identical DNA neutral filter elution dose-response: implications for a relationship between cell radiosensitivity and induction of DNA double-strand breaks. International Journal of Radiation Biology, 54, 55-62.
19. JEGGO, P. A. and KEMP, L. M., 1983, X-ray sensitive mutants of Chinese hamster ovary cell line: Isolation and cross-sensitivity to other DNA damaging agents. Mutation Research, 112, 313-327.
20. JONES, L. A., CLEGG, S., BUSH, C., MCMILLAN, T. J. and PEACOCK, J. H., 1994, Relationship between chromosome aberrations, micronuclei and cell kill in two human tumour cell lines of widely differing radiosensitivity. International Journal of Radiation Biology, 66, 639-642.
21. JOSHI, C. P., NELSON, W. J., REVELL, S. H. and SHAW, C. A., 1982, X-ray induced chromosome damage in live mammalian cells; an improved measurement of its effect on their colony forming ability. International Journal of Radiation Biology, 41, 161-181.
22. KEMP, L. M. and JEGGO, P. A., 1986, Radiation induced chromosome damage in X-ray sensitive mutants (xrs) of the Chinese hamster ovary cell line. Mutation Research DNA Repair Reports, 166, 255-263.
23. LEHMANN, A. R. and STEVENS, S., 1977, The production and repair of double-strand breaks in cells from normal humans and from patients with ataxia telangiectasia. Biochimica Biophysica Acta, 474, 49-60.
24. MALYAPA, R. S., WRIGHT, W. D. and ROTI ROTI, J. L., 1994, Radiation sensitivity correlates with changes in DNA supercoiling and nucleoid protein content in cells of three Chinese cell lines. Radiation Research, 140, 312-320.
25. 1 phase of the cell cycle. Mutation Research DNA Repair Reports, 315, 181-187.
26. MCMILLAN, T. J. and PEACOCK, J. H., 1994, Molecular determinants of radiosensitivity in mammalian cells. International Journal of Radiation Biology, 65, 49-55.
27. 2 ataxia telangiectasia cells exposed to X-rays and ara A. International Journal of Radiation Biology, 55, 71-84.
28. NATARAJAN, A. T. and OBE, G., 1984, Molecular mechanisms involved in the production of chromosomal aberrations III. Restriction endonucleases. Chromosoma, 90, 120-127.
29. 2 stages of the cell cycle. Mutation Research, 69, 293-305.
30. OKAVASU, R. and ILIAKIS, G., 1994, Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics. Radiation Research, 138, 34-43.
31. PANDITA, T. K. and HITTELMAN, W. N., 1992, Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells. Radiation Research, 130, 94-103.
32. RADFORD, I. R., 1986, Evidence for a general relationship between the induced level of DNA double-strand breakage and cell killing after X-irradiation of mammalian cells. International Journal of Radiation Biology, 49, 611-620.
33. RUIZ DE ALMODOVAR, J. M., NUNEZ, M. I., MCMILLAN, T. J., OLEA, N., MORT, C., VILLALOBOS, M., PREDRAZA, V. and STEEL, G. G., 1994, Initial radiation-induced DNA damage in human tumour cell lines: a correlation with intrinsic cellular radiosensitivity. British Journal of Cancer, 69, 457-462.
34. 2 chromatin radiosensitivity in predisposition to cancer. International Journal of Radiation Biology, 55, 963-981.
35. SASAI, K., EVANS, J. W., KOVACS, M. S. and BROWN, M. J., 1994, Prediction of human cell radiosensitivity: comparison of clonogenic assay with chromosome aberrations scored using premature chromosome condensation with fluorescence in situ hybridisation. International Journal of Radiation Oncology, Biology and Physics, 30, 1127-1132.
36. SAVAGE, J. R. K., 1986, The 'Revell Loop'. Clinical Cytogenetics Bulletin, 1, 192-196.
37. SAVAGE, J. R. K. and HARVEY, A. N., 1991, Revell revisited. Mutation Research, 250, 307-317.
38. SAX, K., 1940, An analysis of X-ray induced chromosomal aberrations in Tradescantia. Genetics, 25, 41-68.
39. SCHWARTZ, J. L., BRINKMAN, W. J., KASTEN, L., MILLER, D. W., MOAN, E. I., MURPHY, Y. T., STELLA, D. and SEDITA, B. A., 1995, Altered metaphase chromosome structure in xrs5 is not related to its radiation sensitivity or defective DNA break rejoining. Mutation Research, 328, 119-126.
40. SCHWARTZ, J. L., COWEN, J. M., MOAN, E., SEDITA, B. A., STEPHENS, J. and VAUGHAN, A T. M., 1993, Metaphase chromosome and nucleoid differences between CHO-K1 and its radiosensitive derivative xrs5. Mutagenesis, 8, 105-108.
41. SCOTT, D., SPREADBOROUGH, A. and LEVINE E., 1994, Genetic predisposition in breast cancer. Lancet, 344, 1444.
42. SCOTT, D., SPREADBOROUGH, A. R., JONES, L. A., ROBERTS, S. A. and MOORE, C. J., 1996, Chromosomal radiosensitivity in G2-phase lymphocytes as an indicator of cancer predisposition. Radiation Research, 145, 3-16.
43. SLIJEPCEVIC, P., BRYANT, P. E. and NATARAJAN, A. T., New telomeres at broken chromatid ends in irradiated Chinese hamster fibroblasts. Chromosome Research (in press).
44. SMEETS, M. F. M. A., MOOREN, E. H. M. and BEGG, A. C., 1993, Radiation induced DNA damage and repair in radiosensitive and radioresistant human tumour cells measured by field inversion gel electrophoresis. International Journal of Radiation Biology, 63, 703-713.
45. STAMATO, E. D., WEINSTEIN, R., GIACCIA, A., MACKENZIE, L., 1983, Isolation of a cell cycle-dependent gamma-ray sensitive Chinese hamster ovary cell. Somatic Cell Genetics, 9, 165-173.
46. WURM, R., BURNET, N. G., DUGGAL, N., YARNOLD, J. R. and PEACOCK, J., 1994, Cellular radiosensitivity and DNA damage in primary human fibroblasts. International Journal of Radiation Oncology, Biology and Physics, 30, 625-633.
47. YASUI, L. S., FINK, T. J. and ENRIQUE, A. M., 1994, Nuclear scaffold organisation in the X-ray sensitive Chinese hamster mutant cell line, xrs5. International Journal of Radiation Biology, 65, 185-192.