Affinity-purified dengue-2 virus envelope glycoprotein induces neutralizing antibodies and protective immunity in mice

Vaccine

Volumn 15, Issue 17-18, 1997, Pages 1946-1954

  Staropoli, Isabelle ^a   Frenkiel, Marie Pascale ^a   Mégret, Françoise ^a   Deubel, Vincent ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Baculovirus; Dengue virus; Purified envelope protein; Vaccine development

Indexed keywords

DENGUE VACCINE; NEUTRALIZING ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CONTROLLED STUDY; DENGUE VIRUS; FEMALE; IMMUNITY; IMMUNIZATION; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; SEROCONVERSION;

ANIMALS; ANTIBODIES, VIRAL; BACULOVIRIDAE; CERCOPITHECUS AETHIOPS; CHROMATOGRAPHY, AFFINITY; DENGUE HEMORRHAGIC FEVER; DIMERIZATION; MALE; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; RECOMBINANT PROTEINS; SPODOPTERA; VERO CELLS; VIRAL ENVELOPE PROTEINS;

EID: 0030846892     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(97)00128-X     Document Type: Article

References (63)

1. Monath, T.P. Yellow fever and dengue - the interactions of virus, vector and host in the re-emergence of epidemic disease. Seminars in Virology 1994, 5, 133-145.
2. Halstead, S. B. Pathogenesis of dengue: challenges to molecular biology. Science 1988, 239, 476-481.
3. Monath, T.P. and Heinz, F.X. Flaviviruses. In: Fields Virology (Eds Fields, B.N., Knipe, D.M. and Howley, P.M. et al.). Lippincott-Raven, Philadelphia, 1996, pp. 961-1034.
4. Rey, F., Heinz, F.X., Mandl, C., Kunz, C. and Harrison, S.C. The envelope glycoprotein from tick-borne encephalitis virus at 2A resolution. Nature 1995, 375, 291-298.
5. Johnson, A.J., Guirakhoo, F. and Roehrig, J.T. The envelope glycoproteins of dengue 1 and dengue 2 viruses grown in mosquito cells differ in their utilization of potential glycosylation sites. Virology 1994, 203, 241-249.
6. Heinz, F.X. and Roehrig, J.T. Flaviviruses. In: Immunochemistry of Viruses, II. The Basis for Serodiagnosis and Vaccines (Eds van Regenmortel, M.H.V. and Neurath, A.R.). Elsevier, Amsterdam, 1990, pp. 289-305
7. Venugopal, K. and Gould, E.A. Towards a new generation of flavivirus vaccines. Vaccine 1994, 12, 966-975
8. Zhao, B., Prince, G., Horswood, R., Eckels, K., Summers, P., Chanock, R. and Lai, C.-J. Expression of dengue virus structural proteins and nonstructural protein NS1 by a recombinant vaccinia virus. Journal of Virology 1987, 61, 4019-4022.
9. Staropoli, I., Clément, J.M., Frenkiel, M.P., Hofnung, M. and Deubel, V. Dengue virus envelope glycoprotein can be secreted from insect cells as a fusion with the maltose-binding protein. Journal of Virological Methods 1996, 56, 179-189.
10. Putnak, R., Feighny, R., Burrous, J., Cochran, M., Hackett, C., Smith, G. and Hoke, C. Dengue-1 virus envelope glycoprotein gene expressed in recombinant baculovirus elicits virus-neutralizing antibody in mice and protects them from virus challenge. American Journal of Tropical Medicine and Hygiene 1991, 45, 159-167.
11. Men, R., Bray, M. and Lai, C.-J. Carboxy-terminally truncated dengue virus envelope glycoproteins expressed on the cell surface and secreted extracellularly exhibit increased immunogenicity in mice. Journal of Virology 1991, 65, 1400-1407.
12. Fonseca, B.A.L., Pincus, S., Shope, R.E., Paoletti, E. and Mason, P.W. Recombinant vaccinia viruses co-expressing dengue-1 glycoproteins prM and E induce neutralizing antibodies in mice. Vaccine 1994, 12, 279-285.
13. Feighny, R., Burrous, J. and Putnak, R. Dengue Type-2 virus envelope protein made using recombinant baculovirus protects mice against virus challenge. American Journal of Tropical Medicine and Hygiene 1994, 50, 322-328.
14. Delenda, C., Staropoli, I., Frenkiel, M.P., Cabanié, L. and Deubel, V. Analysis of C-terminally truncated dengue 2 and dengue 3 virus envelope glycoproteins: processing in insect cells and immunogenic properties in mice. Journal of General Virology 1994, 75, 1569-1578.
15. Delenda, C., Frenkiel, M.P. and Deubel, V. Protective efficacy in mice of a secreted form of recombinant dengue-2 virus envelope protein produced in baculovirus-infected insect cells. Archives of Virology 1994, 139, 197-207.
16. Allison, S.L., Stadler, K., Mandl, C.W., Kunz, C. and Heinz, F.X. Synthesis and secretion of recombinant tick-borne encephalitis virus protein-E in soluble and particulate form. Journal of Virology 1995, 69, 5816-5820.
17. Heinz, F.X., Allison, S.L., Stiasny, K., Schalich, J., Holzmann, H., Mandl, C.W. and Kunz, C. Recombinant and virion-derived soluble and particulate immunogens for vaccination against tick-borne encephalitis. Vaccine 1995, 13, 1636-1642.
18. Schlesinger, J.J., Brandriss, M.W., Cropp, C.B. and Monath, T.P. Protection against yellow fever in monkeys by immunization with yellow fever virus nonstructural protein NS1. Journal of Virology 1986, 60, 1153-1155.
19. Desprès, P., Frenkiel, M.P. and Deubel, V. Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure. Virology 1993, 196, 209-219.
20. Deubel, V., Kinney, R.M., Esposito, J.J., Cropp, C.B., Vorndam, A.V., Monath, T.P. and Trent, D.W. Dengue 2 virus envelope protein expressed by a recombinant vaccinia virus fails to protect monkeys against dengue. Journal of General Virology 1988, 69, 1921-1929.
21. Reed, L.J. and Muench, H. A simple method of estimating fifty per cent end points. American Journal of Hygiene 1938, 27, 493-497.
22. Summers, M.D. and Smith, G.E. A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedure. Texas Agricultural Experiment Station Bulletin No. 1555, 1987
23. Deubel, V., Kinney, R.M. and Trent, D.W. Nucleotide sequence and deduced amino-acid sequence of the structural proteins of dengue type 2 virus, Jamaica genotype. Virology 1986, 155, 365-377.
24. Deubel, V., Laille, M., Hugnot, J.P., Chungue, E., Guesdon, J.L., Drouet, M.T., Bassot, S. and Chevrier, D. Identification of dengue sequences by genomic amplification: rapid diagnosis of dengue virus serotype in peripheral blood. Journal of Virological Methods 1990, 30, 41-54.
25. Laemmli, U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227, 680-685.
26. Mégret, F., Hugnot, P.J., Falconar, A., Gentry, M.K., Morens, D.M., Murray, J.M., Schlesinger, J.J., Wright, P.J., Young, P., Van Regenmortel, M.H.V. and Deubel, V. Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein. Virology 1992, 187, 480-491.
27. Deubel, V., Bordier, M., Mégret, F., Gentry, M.K., Schlesinger, J.J. and Girard, M. Processing, secretion, and immunoreactivity of carboxy terminally truncated dengue-2 virus envelope proteins expressed in insect cells by recombinant baculo-viruses. Virology 1991, 180, 442-447.
28. Hochuli, E., Bannwarth, W., Döbeli, H., Gentz, R. and Stüber, D. Genetic approach to facilitate purification of recombinant proteins with a novel metal chelate adsorbent. Bio/Technology 1988, November, 1321-1325.
29. Marianneau, P., Mégret, F., Olivier, R., Morens, D.M. and Deubel, V. Dengue 1 virus binding to human hepatoma HepG2 and simian Vero cell surfaces differs. Journal of General Virology 1996, 77, 2547-2554.
30. Anderson, R., King, A.D. and Innis, B.L. Correlation of E protein binding with cell susceptibility to dengue 4 virus infection. Journal of General Virology 1992, 73, 2155-2159.
31. Gollins, S.W. and Portfield, J.S. Flavivirus infection enhancement in macrophages: an electron-microscopic study of viral cellular entry. Journal of General Virology 1985, 66, 469-473.
32. Smucny, J.J., Kelly, E.P., Macarthy, P. and King, A.D. Murine immunoglobulin G subclass responses following immunization with live dengue virus or a recombinant dengue envelope protein. American Journal of Tropical Medicine and Hygiene 1995, 53, 432-437.
33. + human cytotoxic T lymphocytes. Journal of Virology 1989, 63, 5086-5091.
34. Konishi, E., Kurane, I., Mason, P.W., Innis, B.L. and Ennis, F.A. Japanese encephalitis virus-specific proliferative responses of human peripheral blood T lymphocytes. American Journal of Tropical Medicine and Hygiene 1995, 53, 278-283.
35. Kutubuddin, M., Kolaskar, A.S., Galande, S., Gore, M.M., Ghosh, S.N. and Banerjee, K. Recognition of helper T cell epitopes in envelope (E) glycoprotein of Japanese encephalitis, West Nile and dengue viruses. Molecular Immunology 1991, 28, 149-154.
36. Feighny, R., Burrous, J., McCown, J., Hoke, C. and Putnak, R. Purification of native dengue-2 viral proteins and the ability of purified proteins to protect mice. American Journal of Tropical Medicine and Hygiene 1992, 47, 405-412.
37. Leclerc, C., Dériaud, E., Mégret, F., Briand, J.-P., Van Regenmortel, M.H.V. and Deubel, V. Identification of helper T-cell epitopes of dengue virus E-protein. Molecular Immunology 1993, 30, 613-625.
38. Mathews, J.H., Allan, J.E., Roehrig, J.T., Brubaker, J.R., Uren, M.F. and Hunt, A.R. T-helper cell and associated antibody response to synthetic peptides of the E glycoprotein of Murray valley encephalitis virus. Journal of Virology 1991, 65, 5141-5148.
39. Matsuura, Y., Miyamoto, M., Sato, T., Morita, C. and Yasui, K. Characterization of Japanese encephalitis virus envelope protein expressed by recombinant baculoviruses. Virology 1989, 173, 674-682.
40. Makino, Y., Tadano, M., Arakaki, S. and Fukunaga, T. Potential use of a baculovirus-expressed dengue-4 E protein as a diagnostic antigen in regions endemic for dengue and Japanese encephalitis. American Journal of Tropical Medicine and Hygiene 1991, 45, 636-643.
41. Desprès, P., Dietrich, J., Girard, M. and Bouloy, M. Recombinant baculoviruses expressing yellow fever virus E and NS1 proteins elicit protective immunity in mice. Journal of General Virology 1991, 72, 2811-2816.
42. Eckels, K.H., Dubois, D.R., Summers, P.L., Schlesinger, J.J., Shelly, M., Cohen, S., Zhang, Y.-M., Lai, C.-J., Kurane, I., Rothman, A., Hasty, S. and Howard, B. Immunization of monkeys with baculovirus-dengue type-4 recombinants containing envelope and non-structural proteins: evidence of priming and partial protection. American Journal of Tropical Medicine and Hygiene 1994, 50, 472-478.
43. Konishi, E., Pincus, S., Paoletti, E., Shope, R.E., Burrage, T. and Mason, P.W. Mice immunized with a subviral particle containing the Japanese encephalitis virus prM/M and E proteins are protected from lethal JEV infection. Virology 1992, 188, 714-720.
44. Konishi, E., Pincus, S., Paoletti, E., Shope, R.E. and Mason, P.W. Avipox virus-vectored Japanese encephalitis virus vaccines: use as vaccine candidates in combination with purified subunit immunogens. Vaccine 1994, 12, 633-638.
45. Pincus, S., Mason, P.W., Konishi, E., Fonseca, B.A.L., Shope, R.E., Rice, C.M. and Paoletti, E. Recombinant vaccinia virus producing the prM and E proteins of yellow fever virus protects mice from lethal yellow fever encephalitis. Virology 1992, 187, 290-297.
46. Shiu, S.Y.W., Morikawa, S., Buckley, A., Higgs, S., Karunakarannair, V., Blachere, C. and Gould, E.A. 17D yellow fever vaccine virus envelope protein expressed by recombinant baculovirus is antigenically indistinguishable from authentic viral protein. Journal of General Virology 1991, 72, 1451-1454.
47. Venugopal, K., Jiang, W.R. and Gould, E.A. Immunity to St Louis encephalitis virus by sequential immunization with recombinant vaccinia and baculovirus derived PrM/E proteins. Vaccine 1995, 13, 1000-1005.
48. Zhang, Y.M., Hayes, E.P., McCarty, T.C., Dubois, D.R., Summers, P.L., Eckels, K.H., Chanock, R.M. and Lai, C.-J. Immunization of mice with dengue structural proteins and nonstructural proteins NS1 expressed by baculovirus recombinant induces resistance to dengue virus encephalitis. Journal of Virology 1988, 62, 3027-3031.
49. McCown, J., Cochran, M., Putnak, R., Feighny, R., Burrous, J., Henchal, E. and Hoke, C. Protection of mice against lethal Japanese encephalitis with a recombinant baculovirus vaccine. American Journal of Tropical Medicine and Hygiene 1990, 42, 491-499.
50. Jan, L.-R., Yang, C.-S., Henchal, L.S., Sumiyoshi, H., Summers, P.L., Dubois, D.R. and Lai, C.-J. Increased immunogenicity and protective efficacy in outbred and inbred mice by strategic carboxy-terminal truncation of Japanese encephalitis virus envelope glycoprotein. American Journal of Tropical Medicine and Hygiene 1993, 48, 412-423.
51. Sisk, W.P., Bradley, J.D., Leipold, R.J., Stoltzfus, A.M., Ponce de Leon, M., Hilf, M., Peng, C., Cohen, G.H. and Eisenberg, R.J. High-level expression and purification of secreted forms of herpes simplex virus type 1 glycoprotein gD synthesized by baculovirus-infected insect cells. Journal of Virology 1994, 68, 766-775.
52. Audibert, F. and Lise, L.D. Adjuvants: current status, clinical perspectives and future prospects. Immunology Today 1993, 14, 281-284.
53. Vogel, F.R. The role of adjuvants in retroviral vaccines. Int. J. Immunopharm. 1995, 17, 85-90.
54. Barrios, C., Brawand, P., Berney, M., Brandt, C., Lambert, P.-H. and Siegrist, C.-A. Neonatal and early life immune responses to various forms of vaccine antigens qualitatively differ from adult responses: predominance of a Th2-biased pattern which persists after adult boosting. European Journal of Immunology 1996, 26, 1489-1496.
55. Brett, S.J., Dunlop, L., Liew, F.Y. and Tite, J.P. Influence of the antigen delivery system on immunoglobulin isotype selection and cytokine production in response to influenza A nucleoprotein. Immunology 1993, 80, 306-312.
56. Phillipps, N.C. and Emili, A. Enhanced antibody response to liposome-associated protein antigens: preferential stimulation of lgG2a/b production. Vaccine 1992, 10, 151-158.
57. Hocart, M.J., Mackenzie, J.S. and Steward, G.A. The immunoglobulin G subclass responses of mice to influenza A virus: the effect of mouse strain, and the neutralizing abilities of individual protein A-purified subclass antibodies. Journal of General Virology 1989, 70, 2439-2448.
58. Dillon, S.B., Demuth, S.G., Schneider, M.A., Weston, C.B., Jones, C.S., Young, J.F., Scott, M., Bhatnaghar, P.K., LoCastro, S. and Hanna, N. Induction of protective class I MHC-restricted CTL in mice by a recombinant influenza vaccine in aluminium hydroxide adjuvant. Vaccine 1992, 10, 309-318.
59. Slack, J.H. Strain-dependent IgG subclass response patterns. Journal of Immunology 1987, 139, 3734-3738.
60. Coutelier, J.-P., van der Logt, J.T.M., Heesen, F.W.A., Warnier, G. and van Snick, J. IgG2a restriction of murine antibodies elicited by viral infections. Journal of Experimental Medicine 1987, 165, 64-69.
61. Holmgren, J., Lycke, N. and Czerkinsky, C. Cholera toxin and cholera B subunit as oral-mucosal adjuvant and antigen vector systems. Vaccine 1993, 11, 1179-1184.
62. McKendall, R.R. and Woo, W. Murine IgG subclass responses to herpes simplex virus type 1 and polypeptides. Journal of General Virology 1988, 69, 847-857.
63. Kipps, T.J., Parham, P., Punt, J. and Herzenberg, L.A. Importance of immunoglobulin isotype in human antibody-dependent, cell-mediated cytotoxicity directed by murine monoclonal antibodies. Journal of Experimental Medicine 1985, 161, 1-17.