Cell death in perinatal hypoxic-ischaemic brain injury

Neuropathology and Applied Neurobiology

Volumn 23, Issue 4, 1997, Pages 307-314

  Scott, R J ^a,b   Hegyi, L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Apoptosis; Birth asphyxia; Brain; Human; Infant stillbirth

Indexed keywords

APOPTOSIS; ARTICLE; BRAIN HYPOXIA; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CLINICAL ARTICLE; DISEASE DURATION; DISEASE SEVERITY; DNA REPAIR; FETUS; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; NERVE CELL DEGENERATION; NEWBORN; NEWBORN DEATH; PERINATAL MORBIDITY; PERINATAL PERIOD; PONS; PRIORITY JOURNAL; STILLBIRTH;

EID: 0030836433     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2990.1997.tb01300.x     Document Type: Article

References (30)

1. Beilharz E, Williams C, Dragunow M, Sirimanne E, Gluckman P. Mechanisms of delayed cell death following hypoxic ischaemic injury in the immature rat: evidence for apoptosis during selective neuronal loss. Mol Brain Res 1995; 29: 1-14
2. Bejar R, Wozniak P, Allard M et al. Antenatal origin of neurologic damage in newborn infants. I. Preterm infants. Am J Obstet Gynecol 1988; 159: 357-63
3. Berges R, Furuya Y, Remington L et al. Cell proliferation, DNA repair, and p53 function are not required for programmed death of prostatic glandular cells induced by androgen ablation. Proc Natl Acad Sci USA 1993; 90: 8910-14
4. Brück Y, Brück W, Kretzschmar H, Lassmann H. Evidence for neuronal apoptosis in pontosubicular neuron necrosis. Neuropathol Appl Neurobiol 1996; 22: 23-9
5. Coates P, Save V, Ansari B, Hall P. Demonstration of DNA damage/repair in individual cells using in situ end labelling: association of p53 with sites of DNA damage. J Pathol 1995; 176: 19-26
6. Dragunow M, Beilharz E, Sirimanne E et al. Immediate-early gene protein expression in neurons undergoing delayed death, but not necrosis, following hypoxic-ischaemic injury to the young rat brain. Mol Brain Res 1994; 25: 19-33
7. Friede R. In: Developmental Neuropathology. Berlin: Springer-Verlag, 1989: 90-4
8. Gravrieli Y, Sherman Y, Ben-Sasson S. Identification of programmed cell death in situ via specific labelling of nuclear DNA fragmentation. J Cell Biol 1992; 119: 493-501
9. Gold, R, Schmied M, Giegerich G et al. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Inves 1994; 71: 219-25
10. Grant A, O'Brien N, Joy M, Hennessy E, Macdonald D. Cerebral palsy among children born during the Dublin randomised trial of intrapartum monitoring. Lancet 1989; 2: 1233-6
11. Greenlund L, Deckwerth T, Johnson E. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death. Neuron 1995; 14: 303-15
12. Halliwell B, Dizdaroglu M. The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radic Res Commun 1992; 16: 75-87
13. Hardwick S, Hegyi L, Clark K et al. Apoptosis in human monocyte-macrophages exposed to oxidized low density lipoprotein. J Pathol 1996; 179: 294-302
14. Hegyi L, Skepper J, Cary N, Mitchinson M. Foam cell apoptosis and the development of the lipid core of human atherosclerosis. J Pathol 1996; 180: 423-9
15. Johnson E, Greenlund L, Akins P, Hsu C. Neuronal apoptosis: current understanding of molecular mechanisms and potential role in ischaemic brain injury. J Neurotrauma 1995; 12: 843-52
16. Johnston B, Mallard E, Williams C, Gluckman P. Intrauterine asphyxia and brain development. Dev Brain Dys 1995; 8: 138-51
17. Kerr J, Wyllie A, Currie A. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-57
18. Mehmet H, Edwards A, Hypoxia, ischaemia and apoptosis. Arch Dis Child 1996; 75: F73-F75
19. Mehmet H, Yue X, Squier M et al. Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult. Neurosci Lett 1994; 181: 121-5
20. Petito CK, Roberts B. Effect of post-mortem interval on in situ end labelling of DNA oligonucleosomes. J Neuropathol Exp Neurol 1995; 54: 761-5
21. Pulsinelli W, Brierley J, Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischaemia. Ann Neurol 1982; 11: 491-8
22. Scott R, Hegyi L, Kelly J, Lewis C. Apoptosis in intrauterine hypoxic brain injury. Pathol Int 1996; 46(Supplement 1): Abstract 10
23. Shivji KK, Kenny MK, Wood RD. Proliferating cell nuclear antigen is required for DNA excision repair. Cell 1992; 69: 367-74
24. Skullerud K, Skaeraasen J. Clinicopathological study of germinal matrix haemorrhage, pontosubicular necrosis, and periventricular leukomalacia in stillborn. Child's Nerv Syst 1988; 4: 88-91
25. Squier M, Keeling JW. The incidence of prenatal brain injury. Neuropathol Appl Neurobiol 1991; 17: 29-38
26. Voyvodic J. Cell death in cortical development: how much? so what? Neuron 1996; 16: 693-6
27. Wigglesworth J, Bridger J. Neuropathological clues to the timing of early brain lesions. In: Lou H, Griesen G, Larsen J, eds. Brain Lesions in the Newborn. Hypoxic and Haemodynamic Pathogenesis. Copenhagen: Munksgaard, 1994: 165-77
28. Wyatt J, Edwards A, Azzopardi D, Reynolds E. Magnetic resonance and near infrared spectroscopy for investigation of perinatal hypoxic-ischaemic brain injury. Arch Dis Child 1989; 64: 953-63
29. Wyllie A. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980; 284: 555-6
30. Wyllie A, Kerr J, Currie A. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251-305.