Characterization of a murine model for the rapid assessment of acute photodynamic response in tumour and muscle

Lasers in Medical Science

Volumn 12, Issue 4, 1997, Pages 336-341

  Ansell, J K ^a   De Jode, M L ^a   Grahn, M F ^a  

^a ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Dose response relationships; Neoplasms, experimental; Photochemotherapy; Temoporfin (mTHPC)

Indexed keywords

ALCOHOL; DRUG VEHICLE; MACROGOL 400; PHOTOSENSITIZING AGENT; TEMOPORFIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; COLORECTAL TUMOR; CONTROLLED STUDY; HISTOPATHOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; LIGHT; MOUSE; MUSCLE INJURY; NONHUMAN; PHOTOCHEMOTHERAPY; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; TISSUE NECROSIS;

EID: 0030834482     PISSN: 02688921     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02767156     Document Type: Article

References (10)

1. Berenbaum MC, Bonnett R, Scourides FA. In vivo biological activity of the components of haematoporphyrin derivative. Br J Cancer 1982, 45:571-81
2. Chevretton EB, Berenbaum MC, Bonnett R. The effect of photodynamic therapy on normal skeletal muscle in an animal model. Lasers Med Sci 1992, 7:101-10
3. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986, i:307-10
4. Abulafi AM, Dejode M, Allardice JT et al. Adjuvant intraoperative photodynamic therapy in experimental colorectal cancer. Br J Surg 1995, 82:178-81
5. van Geel IP, Oppelaar H, Oussoren YG et. al. Photosensitizing efficacy of MTHPC-PDT compared to photofrin-PDT in the RIF1 mouse tumour and normal skin. Int J Cancer 1995, 60:388-94
6. Berenbaum MC, Bonnett R, Chevretton EB et al. Selectivity of meso-Tetra(hydroxyphenyl)porphyrins and chlorins and of Photofrin II in causing photodamage in tumour, skin, muscle and bladder. The concept of cost-benefit in analysing the results. Lasers Med Sci 1993, 8:235-43
7. Bonnett R, White RD, Winfield UJ, Berenbaum MC. Hydroporphyrins of the meso-tetra(hydroxyphenyl) porphyrin series as tumour photosensitizers. Biochem J 1989, 261:277-80
8. Ris HB, Altermatt HJ, Stewart CM et al. Photodynamic therapy with m-tetrahydroxyphenylchlorin in vivo: optimization of the therapeutic index. Int J Cancer 1993, 55:245-9
9. Ris HB, Altermatt HJ, Nachbur B et al. Effect of drug-light interval on photodynamic therapy with meta-tetrahydroxyphenylchlorin in malignant mesothelioma. Int J Cancer 1993, 53:141-6
10. Whelpton R, Michael-Titus AT, Jamdar RP et al. Distribution and excretion of radiolabelled temoporphyn in a murine tumour model. Photochem Photobiol 1996, 63:885-91