Stability of the ligand-estrogen receptor interaction depends on estrogen response element flanking sequences and cellular factors

Journal of Steroid Biochemistry and Molecular Biology

Volumn 59, Issue 5-6, 1996, Pages 413-429

  Anolik, Jennifer H ^a,b   Klinge, Carolyn M ^a,b   Brolly, Colleen L ^a   Bambara, Robert A ^a   Hilf, Russell ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYTAMOXIFEN; ANTIESTROGEN; ESTROGEN RECEPTOR; TAMOXIFEN AZIRIDINE;

AFFINITY CHROMATOGRAPHY; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CATTLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA BINDING; FEMALE; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN MODIFICATION; PROTEIN PURIFICATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CATTLE; CHROMATOGRAPHY, AFFINITY; ELECTROPHORESIS; ESTRADIOL; FEMALE; LIGANDS; OLIGONUCLEOTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ESTROGEN; TAMOXIFEN;

EID: 0030479144     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(96)00129-X     Document Type: Article

References (58)

1. 1. Mangelsdorf D. J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P. and Evans R. M.: The nuclear receptor superfamily: the second decade. Cell 83 (1995) 835-839.
2. 2. Martinez E., Dusserre Y., Wahli W. and Mermod N.: Synergistic transcriptional activation by CTF/NF-I and the estrogen receptor involved stabilized interactions with a limiting target factor. Molec. Cell. Biol. 11 (1991) 2937-2945.
3. 3. Nowakowski B. E. and Maurer R. A.: Multiple Pit-1-binding sites facilitate estrogen responsiveness of the prolactin gene. Molec. Endocr. 8 (1994) 1742-1749.
4. 4. Halachmi S., Marden E., Martin G., MacKay H., Abbondanza C. and Brown M.: Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science 264 (1994) 1455-1458.
5. 5. Cavailles V., Dauvois S., L'Horst F., Lopez G., Hoare S., Kushner P. J. and Parker M. G.: Nuclear factor RIP 140 modulates transcriptional activation by the estrogen receptor. EMBO J. 14 (1995) 3741-3751.
6. 6. Onate S. A., Tsai S. Y., Tsai M.-J. and O'Malley B. W.: Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270 (1995) 1354-1357.
7. 7. Baniahmad C., Nawaz Z., Baniahmad A., Gleeson M. A. G., Tsai M.-J. and O'Malley B. W.: Enhancement of human estrogen receptor activity by SPT6: a potential coactivator. Molec. Endocr. 9 (1995) 34-43.
8. 8. LeDouarin B., Zechel C., Garnier J.-M., Lutz Y., Tora L., Pierrat B., Heery D., Gronemeyer H., Chambon P. and Losson R.: The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 14 (1995) 2020-2033.
9. 9. Edwards D. P., Kuhnel B., Estes P. A. and Nordeen S. K.: Human progesterone receptor binding to mouse mammary tumor virus deoxyribonuecleic acid: dependence on hormone and nonreceptor nuclear factors. Molec. Endocr. 3 (1989) 381-391.
10. 10. Burnside J., Darling D. A. and Chin W. W.: A nuclear factor that enhances binding of thyroid hormone receptors to thyroid hormone response elements. J. Biol. Chem. 265 (1990) 2500-2504.
11. 11. Lee J. W., Ryan F., Swaffield J. C., Johnston S. A. and Moore D. D.: Interaction of thyroid hormone receptor with a conserved transcriptional mediator. Nature 374 (1995) 91-94.
12. 12. Glass C. K., Lipkin S. M., Devary O. V. and Rosenfeld M. G.: Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer. Cell 59 (1989) 697-708.
13. 13. Mukherjee R. and Chambon P.: A single-stranded DNA-binding protein promotes the binding of the purified oestrogen receptor to its responsive element. Nucl. Acids Res. 18 (1990) 5713-5716.
14. 14. Koszewski N. J. and Notides A. C.: Phosphate-sensitive binding of the estrogen receptor to its response elements. Molec. Endocr. 5 (1991) 1129-1136.
15. 15. Landel C. C., Kushner P. J. and Greene G. L.: The interaction of human estrogen receptor with DNA is modulated by receptor-associated proteins. Molec. Endocr. 8 (1994) 1407-1419.
16. 16. Feavers I. M., Jiricny J., Moncharmont B., Saluz H. P. and Jost J.R .: Interaction of two nonhistone proteins with the estradiol response element of the avian vitellogenin gene modulates the binding of estradiol-receptor complex. Proc. Natn. Acad. Sci. U.S.A. 84 (1987) 7453-7457.
17. 17. Geffroy-Roisne S., Duval J. and Thieulant M. L.: Multiple forms of affinity-labeled estrogen receptors in rat distinct pituitary cells. Endocrinology 131 (1992) 1503-1510.
18. 18. Klinge C. M., Peale F. V. Jr, Hilf R., Bambara R. A. and Zain S.: Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro. Cancer Res. 52 (1992) 1073-1081.
19. 19. Anolik J. H., Klinge C. M., Bambara R. A. and Hilf R.: Differential impact of flanking sequences on estradiol-versus 4-hydroxytamoxifen-liganded estrogen receptor binding to estrogen responsive element DNA. J. Steroid Biochem. Molec. Biol. 46 (1993) 713-730.
20. 20. Anolik J. H., Klinge C. M., Hilf R. and Bambara R. A.: Cooperative binding of estrogen receptor to DNA depends on spacing of binding sites, flanking sequence, and ligand. Biochemistry 34 (1995) 2511-2520.
21. 21. Klinge C. M., Traish A. M., Bambara R. A. and Hilf R.: Dissociation of 4-hydroxytamoxifen, but not estradiol or tamoxifen aziridine, from the estrogen receptor when the receptor binds estrogen response element DNA. J. Steroid Biochem. Molec. Biol. 57 (1996) 51-66.
22. 22. Klinge C. M., Traish A. M., Driscoll M. D., Hilf R. and Bambara R. A.: Site-directed estrogen receptor antibodies stabilize 4-hydroxytamoxifen ligand, but not estradiol, and indicate ligand-specific differences in the recognition of estrogen response element DNA in vitro. Steroids 61 (1996) 278-289.
23. 23. Klinge C. M., Bambara R. A. and Hilf R.: What differentiates antiestrogen-liganded versus estradiol-liganded estrogen receptor action?. Oncol. Res. 4 (1992) 137-144.
24. 24. Klinge C. M., Bambara R. A. and Hilf R.: Antiestrogen-liganded estrogen receptor interaction with estrogen responsive element DNA in vitro. J. Steroid Biochem. Molec. Biol. 43 (1992) 249-262.
25. 25. Driscoll M. D., Klinge C. M., Hilf R. and Bambara R. A.: Footprint analysis of estrogen receptor binding to adjacent estrogen response elements. J. Steroid Biochem. Molec. Biol. 58 (1996) 45-61.
26. 26. Peale F. V., Ludwig L. B., Zain S., Hilf R. and Bambara R. A.: Properties of a high-affinity DNA binding site for estrogen receptor. Proc. Natn. Acad. Sci. U.S.A. 85 (1988) 1038-1042.
27. 27. Hayes J. J., Tullius T. D. and Wolffe A. P.: The structure of DNA in a nucleosome. Proc. Natn. Acad. Sci. U.S.A. 87 (1990) 7405-7409.
28. 28. Pavlik E. J. and Coulson P. B.: Hydroxylapatite "batch" assay for estrogen receptor: increased sensitivity over present receptor assays. J. Steroid Biochem. 7 (1976) 357-368.
29. 29. Peale F. V. Jr., Ishibe Y., Klinge C. M., Zain S., Hilf R. and Bambara R. A.: Rapid purification of the estrogen receptor by sequence-specific DNA affinity chromatography. Biochemistry 28 (1989) 8671-8675.
30. 30. Obourn J. D., Koszewski N. J. and Notides A. C.: Hormone-and DNA-binding mechanisms of the recombinant human estrogen receptor. Biochemistry 32 (1993) 6229-6236.
31. 31. Abbondanza C., de Falco A., Nigro V., Medici N., Armetta I., Molinari A. M., Moncharmont B. and Puca G. A.: Characterization and epitope mapping of a new panel of monoclonal antibodies to estradiol receptor. Steroids 58 (1993) 4-12.
32. 32. Ludwig L. B., Klinge C. M., Peale F. V. Jr., Bambara R. A., Zain S. and Hilf R.: A microtiter well assay for quantitative measurement of estrogen receptor binding to estrogen-responsive elements. Molec. Endocr. 4 (1990) 1027-1033.
33. 33. Traish A. M., Al-Fadhli S., Klinge C. M., Kounine M. and Quick T. C.: Identification of structurally-altered estrogen receptors in human breast cancer by site-directed monoclonal antibodies. Steroids 60 (1995) 467-474.
34. 34. Fritsch M., Welch R. D., Murdoch F. E., Anderson I. and Gorski J.: DNA allosterically modulates the steroid binding domain of the estrogen receptor. J. Biol. Chem. 267 (1992) 1823-1828.
35. 35. Maaroufi Y., Trivedi S. and LeClercq G.: Major molecular weight heterogeneity of estrogen receptor from breast cancer is not related to neoplasia. Cancer Biochem. Biophys. 15 (1995) 67-78.
36. 36. Zhang X. Y., Asiedu C. K., Supakar P. C. and Ehrlich M.: Increasing the activity of affinity-purified DNA-binding proteins by adding high concentrations of nonspecific proteins. Analyt. Biochem. 201 (1992) 366-374.
37. 37. Neff S., Sadowski C. and Kiksicek R. J.: Mutational analysis of cysteine residues within the hormone-binding domain of the human estrogen receptor identifies mutants that are defective in both DNA-binding and subcellular distribution. Molec. Endocr. 8 (1994) 1215-1223.
38. 38. Robertson D. W., Wei L. L., Hayes J. R., Carlson K. E., Katzenellenbogen J. A. and Katzenellenbogen B. S.: Tamoxifen aziridines: effective inactivators of estrogen receptors. Endocrinology 109 (1981) 1298-1300.
39. 39. Furlow J. D., Murdoch F. E. and Gorski J.: High affinity binding of the estrogen receptor to a DNA response element does not require homodimer formation or estrogen. J. Biol. Chem. 268 (1993) 12519-12525.
40. 40. Sasson S. and Notides A. C.: Mechanism of the estrogen receptor interaction with 4-hydroxytamoxifen. Molec. Endocr. 2 (1988) 307-312.
41. 41. Thole H. H.: The side chains responsible for the dimerization of the estradiol receptor by ionic bonds are lost in a 17 kDa fragment extending downstream from aa303. J. Steroid Biochem. Molec. Biol. 48 (1994) 463-466.
42. 42. Fawell S. E., Lees J. A., White R. and Parker M. G.: Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor. Cell 60 (1990) 953-962.
43. 43. Zhou Z.-X., Lane M. S., Kemppainen J. A., French F. S. and Wilson E. M.: Specificity of ligand-dependent androgen receptor stabiization: receptor domain interactions influence ligand dissociation and receptor stability. Molec. Endocr. 9 (1995) 208-218.
44. 44. Wang Y. and Sauerbier W.: AT-rich sequences may lower the activation energy of cruciform extrusion in supercoiled DNA. Biochem. Biophys. Res. Commun. 158 (1989) 423-431.
45. 45. Lannigan D. A., Tamashek J. J., Obourn J. D. and Notides A. C.: Analysis of estrogen receptor interaction with tertiary-structured estrogen responsive elements. Biochem. Pharm. 45 (1993) 1921-1928.
46. 46. Kladde M. P., D'Cunha J. and Gorski J.: Multiple transitions to non-B-DNA structures occur in the distal regulatory region of the rat prolactin gene. J. Molec. Biol. 229 (1993) 344-367.
47. 47. Lannigan D. A. and Notides A. C.: Estrogen receptor selectively binds the "coding strand" of an estrogen responsive element. Proc. Natn. Acad. Sci. U.S.A. 86 (1989) 863-867.
48. 48. Pina B., Haché R. J. G., Arnemann J., Chalepakis G., Slater E. P. and Beato M.: Hormonal induction of transfected genes depends on DNA topology. Molec. Cell. Biol. 10 (1990) 625-633.
49. 49. Dana S. L., Hoener P. A., Wheeler D. A., Lawrence C. B. and McDonnell D. P.: Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estogens and antiestrognes in mammalian cells. Molec. Endocr. 8 (1994) 1193-1207.
50. 50. Dobbeling U., Rob K., Klein-Hitpass L., Morley C., Wagner U. and Ryffel G. U.: A cell-specific activator in the Xenopus A2 vitellogenin gene: promoter elements functioning with rat liver nuclear extracts. EMBO J. 7 (1988) 2495-2501.
51. 51. Nardulli A. M. and Shapiro D. J.: Binding of the estrogen receptor DNA-binding domain to the estrogen response element induces DNA bending. Molec. Cell. Biol. 12 (1992) 2037-2042.
52. 52. Nardulli A. M., Grobner C. and Cotter D.: Estrogen receptor-induced DNA bending: orientation of the bend and replacement of an estrogen response element with an intrinsic DNA bending sequence. Molec. Endocr. 9 (1995) 1064-1076.
53. 53. Kahn J. D. and Crothers D. M.: Protein-induced bending and DNA cyclization. Proc. Natn. Acad. Sci. U.S.A. 89 (1989) 6343-6347.
54. 54. Onate S., Prendergast P., Wagner J. P., Nissen M., Reeves R., Pettijohn D. E. and Edwards D. P.: The DNA-bending protein HMG-I enhances progesterone receptor binding to its target DNA sequences. Molec. Cell. Biol. 14 (1994) 3376-3391.
55. 55. Prendergast P., Onate S. A., Christensen K. and Edwards D.: Nuclear accessory factors enhance the binding of progesterone receptor to specific target DNA. J. Steroid Biochem. Molec. Biol. 48 (1994) 1-13.
56. 56. Iyer V. and Struhl K.: Poly(dA:dT), a ubiquitous promoter element that stimulates transcription via its intrinsic DNA structure. EMBO J. 14 (1995) 2570-2579.
57. 57. Tora L., Gaub M. P., Mader S., Dierich A., Bellard M. and Chambon P.: Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter. EMBO J. 7 (1988) 3771-3778.
58. 58. Kupfer S. R., Marshke K. B., Wilson E. M. and French F. S.: Receptor accessory factor enhances specific DNA binding of androgen and glucocorticoid receptor. J. Biol. Chem. 268 (1993) 17519-17527.