Insulin-like growth factors stimulate expression of hepatocyte growth factor but not transforming growth factor β1 in cultured hepatic stellate cells

Endocrinology

Volumn 138, Issue 11, 1997, Pages 4683-4689

  Skrtic, S ^a   Wallenius, V ^a   Ekberg, S ^a   Brenzel, A ^b   Gressner, A M ^b   Jansson, J O ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; MESSENGER RNA; SCATTER FACTOR; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; THYMIDINE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL TRANSFORMATION; DNA CONTENT; DNA SYNTHESIS; DOSE TIME EFFECT RELATION; GENE EXPRESSION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STELLATE CELL;

EID: 0030830203     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.11.5540     Document Type: Article

References (49)

1. Froesch ER, Schmid C, Schwander J, Zapf J 1985 Actions of insulin-like growth factors. Ann Rev Physiol 47:443-467
2. D'Ercole A, Stiles A, Underwood L 1984 Tissue concentrations of somatomedin C: Further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action. Proc Natl Acad Sci USA 81:935-939
3. Isaksson OP, Lindahl A, Nilsson A, Isgaard J 1987 Mechanism of the stimulatory effect of growth hormone on longitudinal bone growth. Endocr Rev 8:426-438
4. Daughaday WH, Rotwein P 1989 Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 10:68-86
5. Gohda E, Yamasaki T, Tsuboushi H, Kurobe M, Sakiyama O, Aoki H, Niidani N, Shin S, Hayashi K, Hashimoto S, Daikuhara Y, Yamamoto I 1990 Bilogical and immunological properties of hepatocyte growth factor from plasma of patients with fulminant hepatic failure. Biochim Biophys Acta 1053:21-26
6. Caro F, Poulos J, Ittoop O, Pories WJ, Flickinger EG, Sinha MK 1988 Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver. J Clin Invest 81:976-981
7. Bachem MG, Meyer D, Schafer W, Riess U, Melchior R, Sell KM, Gressner AM 1993 The response of rat liver perisinusoidal lipocytes to polypeptide growth regulator changes with their transdifferentiation into myofibroblast-like cells in culture. J Hepatol 18:40-52
8. Gressner AM, Brenzel A, Vossmeyer T 1993 Hepatocyte-conditioned medium potentiates insulin-like growth factor (IGF) 1 and 2 stimulated DNA synthesis of cultured fat storing cells. Liver 13:86-94
9. Gressner AM, Lahme B, Brenzel A 1995 Molecular dissection of the mitogenic effect of hepatocytes on cultured hepatic stellate cells. Hepatology 22:1507-1518
10. Pinzani M, Abboud HE, Aron DC 1990 Secretion of insulin-like growth factor-I and binding proteins by rat liver fat-storing cells: regulatory role of platelet-derived growth factor. Endocrinology 127:2343-2349
11. Brenzel A, Gressner AM 1996 Characterization of insulin-like growth factor (IGF)-I-receptor binding sites during in vitro transformation of rat hepatic stellate cells to myofibroblasts. Eur J Clin Chem Clin Biochem 34:401-409
12. Blomhoff R, Wake K 1991 Perisinusoidal stellate cells of the liver: important roles in retinol metabolism and fibrosis. FASEB J 5:271-277
13. Pinzani M 1995 Novel insights into the biology and physiology of the Ito cell. Pharmacol Ther 66:387-412
14. Gressner AM 1996 Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis. Kidney Int 49:39-45
15. Russell WE, Coffey, Jr, RJ, Ouellette AJ, Moses HL 1988 Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Nat Acad Sci USA 85:5126-5130
16. Oberhammer FA, Pavelka M, Sharma S, Tiefenbacher R, Purchio AF, Bursch W, Schulte-Hermann R 1992 Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1. Proc Nat Acad Sci USA 89:5408-5412
17. Schirmacher P, Geerts A, Peitrangelo A, Dienes HP, Rogler CE 1991 Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells. Hepatology 15:5-11
18. Ramadori G, Neubauer K, Odenthal M, Nakamura T, Knittel T, Schwögler S, Meyer zum Büschenfelde K-H 1992 The gene of hepatocyte growth factor is expressed in fat-storing cells of rat liver and is downregulated during cell growth and by transforming growth factor-beta. Biochem Biophys Res Commun 183:739-742
19. Maher JJ 1993 Cell-specific expression of hepatocyte growth factor in liver. J Clin Invest 91:2244-2252
20. Zarnegar R, Michalopoulos GK 1995 The many faces of hepatocyte growth factor: from hepatopoiesis to hematopoiesis. J Cell Biol 129:1177-1180
21. Matsumoto K, Nakamura T 1996 Emerging multipotent aspects of hepatocyte growth factor. J Biochem (Tokyo) 119:591-600
22. Joplin R, Hishida T, Tsubouchi H, Daikuhara Y, Ayres R, Neuberger JM, Strain AJ 1992 Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factor. J Clin Invest 90:1284-1289
23. Johnson M, Koukoulis G, Matsumoto K, Nakamura T, Iyer A 1993 Hepatocyte growth factor induces proliferation and morphogenesis in nonparenchymal epithelial liver cells. Hepatology 17:1052-1061
24. Schafer S, Zerbe O, Gressner AM 1987 The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology 7:680-687
25. Chen W, Gendrault JL, Steffan AM, Jeandidier E, Kirn A 1989 Isolation, culture and main characteristics of mouse fat-storing cells: interaction with viruses. Hepatology 9:352-362
26. Zerbe O, Gressner AM 1988 Proliferation of fat-storing cells is stimulated by secretions of Kupffer cells from normal and injured liver. Exp Mol Pathol 49:87-101
27. Labarca C, Paigen K 1980 A simple, rapid and sensitive DNA assay procedure. Anal Biochem 102:344-352
28. Tashiro K, Hagiya M, Nishizawa T, Seki T, Shimonishi M, Shimizu S, Nakamura T 1990 Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues. Proc Natl Acad Sci USA 87:3200-3204
29. Ekberg S, Luther M, Nakamura T, Jansson J-O 1992 Growth hormone promotes early initiation of hepatocyte growth factor gene expression in the liver of hypophysectomized rats after partial hepatectomy. J Endocrinol 135:59-67
30. Chomczynski P, Sacchi N 1987 Single step method of RNA isolation by acid guanidinum thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159
31. Yamada A, Matsumoto K, Iwanari H, Sekiguchi K, Kawata S, Matsuzawa Y, Nakamura T 1995 Rapid and sensitive enzyme-linked immunosorbent assay for measurement of HGF in rat and human tissues. Biomed Res 16:105-114
32. Bachem MG, Meyer D, Melchior R, Sell KM, Gressner AM 1992 Activation of rat liver perisinusoidal lipocytes by transforming growth factors derived from myofibroblastlike cells. A potential mechanism of self perpetuation in liver fibrogenesis. J Clin Invest 89:19-27
33. Okajima A, Miyazawa K, Kitamura N 1993 Characterization of the promoter region of the rat hepatocyte-growth-factor/scatter-factor gene. Eur J Biochem 213:113-119
34. Liu Y, Michalopoulos GK, Zarnegar R 1994 Structural and functional characterization of the mouse hepatocyte growth factor gene promoter. J Biol Chem 269:4152-4160
35. Aravamudan B, Watabe M, Watabe K 1993 Characterization of the 5′-flanking region of the hepatocyte growth factor gene. Biochem Biophys Res Commun 195:346-353
36. Erondu NE, Dake BL, Moser DR, Lin M, Boes M, Bar RS 1996 Regulation of endothelial IGFBP-3 synthesis and secretion by IGF-1 and TGF-beta. Growth Regul 6:1-9
37. Rubin JS, Bottaro DP, Aaronson SA 1993 Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product. Biochim Biophys Acta 1155:357-371
38. Duan C, Hawes SB, Prevette T, Clemmons DR 1996 Insulin-like growth factor-I (IGF-I) regulates IGF-binding protein-5 synthesis through transcriptional activation of the gene in aortic smooth muscle cells. J Biol Chem 271:4280-4288
39. Florini JR, Ewton DZ, Coolican SA 1996 Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 17:481-517
40. Davis BH 1988 Transforming growth factor beta responsiveness is modulated by the extracellular collagen matrix during hepatic ito cell culture. J Cell Physiol 136:547-553
41. Chin E, Zhou J, Dal J, Baxter RC, Bondy CA 1994 Cellular localization and regulation of gene expression for components of the insulin-like growth factor ternary binding protein complex. Endocrinology 134:2498-2504
42. Villafuerte BC, Koop BL, Pao CI, Gu L, Birdsong GG, Phillips LS 1994 Coculture of primary rat hepatocytes and nonparenchvmal cells permits expression of insulin-like growth factor binding protein-3 in vitro. Endocrinology 134:2044-2050
43. Scharf JG, Ramadori G, Braulke T, Hartmann H 1996 Synthesis of insulinlike growth factor binding proteins and of the acid-labile subunit in primary cultures of rat hepatocytes, of Kupffer cells, and in cocultures: regulation by insulin, insulinlike growth factor, and growth hormone. Hepatology 23:818-827
44. Skrtic S, Wallenius V, Ekberg S, Brenzel A, Gressner A, Jansson J-O 1997 Expression pattern of growth hormone/insulin-like growth factor associated genes in rat liver. in: Wisse E, Knook D, Balabaud C, eds. Cells of the hepatic sinusoid. Vol 6. Kupffer Cell Foundation, Leyden, The Netherlands
45. Arany E, Afford S, Strain AJ, Winwood PJ, Arthur MJ, Hill DJ 1994 Differential cellular synthesis of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 within human liver. J Clin Endocrinol Metab 79:1871-1876
46. Carlsson-Skwirut C, Lake M, Hartmanis M, Hall K, Sara VR 1989 A comparison of the biological activity of the recombinant intact and truncated insulin-like growth factor 1 (IGF-1). Biochim Biophys Acta 1011:192-197
47. Lindroos PM, Zarnegar R, Michalopoulos GK 1991 Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration. Hepatology 13:743-750
48. Miyazawa K, Shimomura T, Kitamura A, Kondo J, Morimoto Y, Kitamura N 1993 Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. J Biol Chem 268:10024-10028
49. van Neste L, Husman B, Möller C, Andersson G, Norstedt G 1988 Cellular distribution of somatogenic receptors and insulin-like growth factor mRNA in the rat liver. J Endocrinol 119:69-74