Cre-mediated recombination at the murine whey acidic protein (mWAP) locus

Molecular Reproduction and Development

Volumn 48, Issue 3, 1997, Pages 324-331

  Rucker, Edmund B ^a,b   Piedrahita, Jorge A ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

Bioreactors; Cre loxP; ES cells; Transgenics; WAP

Indexed keywords

ACID PROTEIN;

ANIMAL CELL; ARTICLE; BREAST DEVELOPMENT; EMBRYO; EMBRYO DEVELOPMENT; GENE CASSETTE; GENE DELETION; GENE INSERTION; GENE LOCUS; GENE TARGETING; GENETIC RECOMBINATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TRANSGENE; TUMOR SUPPRESSOR GENE; WHEY;

ANIMALS; BIOREACTORS; BLOTTING, SOUTHERN; CELL LINE; CLONING, MOLECULAR; DNA; ELECTROPORATION; INTEGRASES; MICE; MICE, TRANSGENIC; MILK PROTEINS; PLASMIDS; RECOMBINATION, GENETIC; STEM CELLS; TRANSGENES; VIRAL PROTEINS;

ANIMALIA; MURINAE;

EID: 0030828375     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2795(199711)48:3<324::AID-MRD4>3.0.CO;2-T     Document Type: Article

References (28)

1. Abuin A, Bradley A (1996): Recycling selectable markers in mouse embryonic stem cells. Mol Cell Biol 16:1851-1856.
2. Albert H, Dale EC, Lee E, Ow DW (1995): Site-specific integration of DNA into wild-type and mutant lox sites placed in the plant genome. Plant J 7:649-659.
3. Alexander CM, Howard EW, Bissell MJ, Werb Z (1996): Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene. J Cell Biol 135:1669-1677.
4. Araki K, Araki M, Yamamura K (1997): Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res 25:868-872.
5. Baubonis W, Sauer B (1993): Genomic targeting with purified cre recombinase. Nucl Acids Res 9:2025-2029.
6. Bradley A, Liu P (1996): Target practice in transgenics. Nature Genet 14:121-123.
7. Brinster RL, Braun RE, Lo D, Avarbock MR, Oran F, Palmiter RD (1989): Targeted correction of a major histocompatability class II Ea gene by DNA microinjection into mouse eggs. Proc Natl Acad Sci USA 86:7087-7091.
8. Gordon JW (1993): Production of transgenic mice. Methods in Enzymol 225:747-771.
9. Grabowski H, Le Bars D, Chene N, Altal J, Malienou-N'Gassa R, Puissant C, Houdebine LM (1991): Rabbit whey acidic protein concentration in milk, serum, mammary gland extract and culture medium. J Dairy Sci 74:4143-4154.
10. Gu G, Zou YR, Rajewski K (1993): Independent control of immunoglobulin switch recombination at individual switch regions evidenced through cre-loxP-mediated gene targeting. Cell 73:1155-1164.
11. Hennighausen L, Sippel AE (1982): Characterization and cloning of the mRNAs specific for the lactating mouse mammary gland. Eur J Biochem 125:131-141.
12. Houdebine LM (1994): Production of pharmaceutical proteins from transgenic animals. J Biotechnol 34:269-287.
13. Humphreys RC, Krajewska M, Krnacik S, Jaeger R, Weiher H, Krajewski S, Reed JC, Rosen JM (1996): Apoptosis in the terminal endbud of the murine mammary gland: A mechanism of ductal morphogenesis. Development 122:4013-4022.
14. Kanegae Y, Gwang L, Sato Y, Tanaka M, Nakai M, Sakaki T, Sugano S, Saito I (1995): Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic Acids Res 23:3816-3821.
15. Klintworth GK (1990): Pathologic states produced in transgenic mice. Adv Pathol 3:233-299.
16. Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, Lee E, Alt FW, Westphal H (1996): Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci USA 93:5860-5865.
17. Liu XL, Wazer DE, Watanabe K, Band V (1996): Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. Cancer Res 15:3371-3379.
18. McKnight RA, Shamay A, Sankaran L, Wall RJ, Hennighausen L (1992): Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice. Proc Nat Acad Sci USA 89:6943-6947.
19. Muller WJ, Arteaga CL, Muthuswarny SK, Siegel PM, Webster MA, Cardiff RD, Meise KS, Li F, Halter SA, Coffey RJ (1996): Synergistic interaction of the Neu proto-oncogene product and transforming growth factor alpha in the mammary epithelium of transgenic mice. Mol Cell Biol 16:5726-5736.
20. O'Gorman S, Fox DT, Wahl GM (1991): Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science 251:1351-1355.
21. Pelletier J, Sonenberg N (1988): Internal initiation of trablation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320-325.
22. Portella G, Salvatore D, Bott G, Cerrato A, Zhang L, Mineo A, Chiappetta G, Santelli G, Pozzi L, Vecchio G, Fusco A, Santoro M (1996): Development of mammary and cutaneous gland tumors in transgenic mice carrying the RET/PTC1 oncogene.
23. Sauer B, Henderson N (1989): Cre-stimulated recombination at loxP-containing DNA sequences placed into the mammalian genome. Nucleic Acids Res 17:147-161.
24. Sauer B, Henderson N (1990): Targeted insertion of exogenous DNA into the eukaryotic chromosome by the ere recombinase. New Biol 2:441-449.
25. Slice SL, Strelchenko NS (1995): Domestic animal embryonic stem cells: Progress toward germ-line contribution. Beltsville Symposium in Agricultural Research XX 189-201.
26. Takayama H, LaRochelle WJ, Sharp R, Otsuka T, Kriebel P, Anver M, Aaronson SA, Merlino G (1997): Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci USA 94:701-706.
27. Tekmal RR, Ramachandra N, Gubba S, Durgam VR, Mantione J, Toda K, Shizuta Y, Dillehay DL (1996): Overexpression of int-5/aromatase in mammary glands of transgenic mice results in the induction of hyperplasia and nuclear abnormalities. Cancer Res 56:3180-3185.
28. Yom O, Bremel R (1993): Genetic engineering of milk composition: Modification of milk components in lactating transgenic animals. Am J Clin Nutr 58:299-312.