Endotoxin-mediated synthesis of nitric oxide is dependent on G(q) protein signal transduction

Surgery

Volumn 122, Issue 2, 1997, Pages 394-403

  Kuo, Paul C ^a,b   Schroeder, Rebecca A ^a   Bartlett, Stephen T ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Department of Surgery ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SURAMIN;

CONFERENCE PAPER; ENZYME INHIBITION; MACROPHAGE FUNCTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0030826546     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(97)90032-5     Document Type: Conference Paper

References (21)

1. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992;6:1157-75.
2. Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD. Cell signaling. In: Alberts B, Bray D, Lewis D, Raff M, Roberts JC, Watson JD, editors. Molecular biology of the cell. New York: Garland; 1994. p 721-87.
3. Snell FD, Snell CT. Colorimetric methods of analysis. New York: D. Van Nostrand; 1984.
4. Gierschik P, Bouillon T, Jakobs K. Receptor stimulated hydrolysis of guanosine 5′-triphosphate in membrane preparations. Methods Enzymol 1994;237:13-26.
5. Cassel D, Selinger Z. Catecholamine stimulated GTPase activity in turkey erythrocyte membranes. Biochim Biophys Acta 1976;452:538-51.
6. Kuo PC, Abe KY. Interleukin-1 induced production of nitric oxide inhibits benzenetriol mediated oxidative injury in rat hepatocytes. Gastroenterology 1995;109:206-16.
7. Lowry OH, Rosebrough NJ, Farr AJ, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75.
8. Neer EJ. Heterotrimeric G proteins: organizers of transmembrane signals. Cell 1995;80:249-57.
9. Dong Z, Qi X, Xie K, Fidler XJ. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages. J Immunol 1993;151:2717-24.
10. Novogrodsky A, Vanichkin A, Patya M, Gazit A, Osherov N, Levitzki A. Prevention of lipopolysaccharide induced lethal toxicity by tyrosine kinase inhibitors. Science 1994;264:1319-22.
11. Tetsuka T, Morrison AR. Tyrosine kinase activation is necessary for inducible nitric oxide synthase expression by interleukin-1. Am J Physiol 1995;269:C55-9.
12. Tachado SD, Gerold P, McConville MJ, Baldwin T, Quilici D, Schwarz RT, et al. Glycosylphosphatidylinositol toxin of plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase dependent and protein kinase C dependent signaling pathway. J Immunol 1996;156:1897-907.
13. Sowa G, Przewlocki R. cAMP analogues and cholera toxin stimulate the accumulation of nitrite in rat peritoneal macrophage cultures. Eur J Pharmacol 1994;266:125-9.
14. Gil-Longo J, Dufour MN, Guillon G, Lugnier C. G proteins in aortic endothelial cells and bradykinin-induced formation of nitric oxide. Eur J Pharmacol 1993;247:119-25.
15. Bosca L, Lazo PA. Induction of nitric oxide release by MRC OX 44 through a protein kinase C dependent pathway in rat macrophages. J Exp Med 1994;179:1119-26.
16. Sands WA, Clark JS, Liew FY. The role of phosphatidylcholine-specific phospholipase C in the production of diacylglycerol for nitric oxide synthesis in macrophages activated by IFN and LPS. Biochem Biophys Res Commun 1994;199:461-6.
17. Sweet MJ, Hume DA. Endotoxin signal transduction in macrophages. J Leukoc Biol 1996;60:8-26.
18. Ingalls RR, Golenbock DT. CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J Exp Med 1995;181:1473-9.
19. Hewett JA, Roth RA. Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacol Rev 1993;45:381-411.
20. Fukuse S, Maeda T, Webb DR, Devens BH. A 69-kDa membrane protein associated with lipopolysaccharide induced signal transduction in the human monocytic cell line, THP-1. Cell Immunol 1995;164:248-54.
21. Lyons CR. The role of nitric oxide in inflammation. Adv Immunol 1995;60:323-71.