Cultured neonatal Schwann cells contain and secrete neuregulins

Journal of Neuroscience Research

Volumn 46, Issue 2, 1996, Pages 263-270

  Raabe, T D ^a,b   Clive, D R ^a,b   Neuberger, T J ^c   Wen, D ^c   DeVries, G H ^a,b  

^a LOYOLA UNIVERSITY   (United States)

^b HINES VA HOSPITAL   (United States)

^c AMGEN INC   (United States)

Author keywords

autocrine; neu differentiation factor; Schwann cell

Indexed keywords

MESSENGER RNA; NEU DIFFERENTIATION FACTOR; POLYCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELL PROLIFERATION; CULTURE MEDIUM; IMMUNOBLOTTING; IMMUNOCHEMISTRY; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; SCHWANN CELL; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CELLS, CULTURED; CYTOSKELETAL PROTEINS; GLYCOPROTEINS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; NEUREGULINS; POLYMERASE CHAIN REACTION; RATS; RECOMBINANT PROTEINS; RNA; SCHWANN CELLS;

EID: 0029998554     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19961015)46:2<263::AID-JNR15>3.0.CO;2-3     Document Type: Article

References (35)

1. Baichwal RR, DeVries GH (1992): A mitogenic factor derived from the myelin membrane. In Martenson R (ed): "Myelin: Biology and Chemistry." Boca Raton, Florida: CRC Press, pp 633-649.
2. Ben-Baruch N, Yarden Y (1994): Neu differentiation factors: a family of alternatively spliced neuronal and mesenchymal factors. Proc Soc Exp Biol Med 206:221-227.
3. Bottenstein JE, Sato GH (1979): Growth of rat neuroblastoma cell line in serum-free supplemented media. Proc Natl Acad Sci USA 76:514-517.
4. Brockes JP, Fields KL, Raff M (1979): Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res 165:105-118.
5. Burgess TL, Ross SL, Qian Y, Brankow D, Hu S (1995): Biosynthetic processing of neu differentiation factor. J Biol Chem 270(32):19188-19196.
6. Canoll P, Reynolds R, Marchionni M, Salzer J (1995): Neuregulins regulate the proliferation and differentiation of oligodendrocyte progenitors. Soc Neurosci Abstr 21:122.3.
7. Carraway KL, Burden SJ (1995): Neuregulins and their receptors. Curr Opin Neurobiol 5:606-612.
8. Carraway KL, Cantley LC (1994): A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling. Cell 78:5-8.
9. Chomczynski P, Sacchi N (1987): Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
10. Cohen JA, Yachnis AT, Arai M, Davis JG, Scherer SS (1992): Expression of the neu proto-oncogene by Schwann cells during peripheral nerve development and Wallerian degeneration. J Neurosci Res 31:622-634.
11. Corfas G, Rosen KM, Aratake H, Krauss R, Fischbach GD (1995): Differential expression of ARIA isoforms in the rat brain. Neuron 14:103-115.
12. Dong Z, Brennan A, Liu N, Yarden Y, Lefkowitz G, Mirsky R, Jessen KR (1995): Neu differentiation factor is a neuron-glia signal and regulates survival, proliferation, and maturation of rat Schwann cell precursors. Neuron 15:585-596.
13. Francoeur JR, Richardson PM, Dunn RJ, Carbonetto S (1995): Distribution of erb-B2, erb-B3, and erb-B4 in the developing avian nervous system. J Neurosci Res 41(6):836-845.
14. Levi ADO, Bunge RP, Lofgren JA, Meima L, Hefti F, Nikolics K, Sliwkowski MX (1995): The influence of heregulins on human Schwann cell proliferation. J Neurosci 15(2):1329-1340.
15. Marchionni MA, Goodearl ADJ, Chen MS, Bermingham-McDonogh O, Kirk C, Hendricks M, Danehy F, Misumi D, Sudhalter J, Kobayashi K, Wroblewski D, Lynch C, Baldassare M, Hiles I, Davis JB, Hsuan JJ, Totty NF, Otsu M, McBurney RN, Waterfield MD, Stroobant P, Gwynne D (1993): Glial growth factors are alternately spliced erbB2 ligands expressed in the nervous system. Nature 362:312-318.
16. Mason P, Neuberger T, Attema B, DeVries GH (1993): Regulation of neu expression in Schwann cell-dorsal root ganglion co-cultures. Soc Neurosci Abstr 19(2):540.8.
17. Massagué J, Pandiella A (1993): Membrane-anchored growth factors. Annu Rev Biochem 62:515-541.
18. Meyer D, Birchmeier C (1994): Distinct isoforms of NRG are expressed in mesenchymal and neuronal cells during mouse development. Proc Natl Acad Sci USA 91:1064-1068.
19. Meyer D, Birchmeier C (1995): Multiple essential functions of neuregulin in development. Nature 378:386-390.
20. erbB2. Proc Natl Acad Sci USA 92:1431-1435.
21. Neuberger TJ, DeVries GH (1992): Axonal contact as a determinant of oligodendrocyte and Schwann cell function. In Martenson R (ed): "Myelin: Biology and Chemistry." Boca Raton, Florida: CRC Press, pp 173-193.
22. Orr-Urteger A, Trakhtenbrot L, Ben-Levy R, Wen D, Rechavi G, Lonai P, Yarden Y (1993): Neural expression and chromosomal mapping of neu differentiation factor to 8p12-p21. Proc Natl Acad Sci USA 90:1867-1871.
23. Peles E, Yarden Y (1993): Neu and its ligands: from an oncogene to neural factors. Bioessays 15(12):815-824.
24. Peles E, Bacus SS, Koski RA, Lu HS, Wen D, Ogden SG, Ben-Levy R, Yarden Y (1992): Isolation of the neu/HER-2 stimulatory ligand: a 44kd glycoprotein that induces differentiation of mammary tumor cells. Cell 69:205-216.
25. Pinkas-Kramarski R, Eilam R, Spiegler O, Lavi S, Liu N, Chang D, Wen D, Schwartz M, Yarden Y (1994): Brain neurons and glial cells express new differentiation factor/heregulin: a survival factor for astrocytes. Proc Natl Acad Sci USA 91:9387-9391.
26. Sandrock AW, Goodearl ADJ, Yin Q-W, Chang D, Fischbach GD (1995): ARIA is concentrated in nerve terminals at neuromuscular junctions and at other synapses. J Neurosci 15(9):6124-6136.
27. Shah NM, Marchionni MA, Isaacs I, Stroobant P, Anderson DJ (1994): Glial growth factor restricts mammalian neural crest stem cells to a glial fate. Cell 77:349-360.
28. Shum L, Reeves SA, Kuo AC, Fromer ES, Derynck R (1994): Association of the transmembrane TGF-α precursor with a protein kinase complex. J Cell Biol 125(4):903-916.
29. Siironen J, Collan Y, Röytta M (1994): Axonal reinnervation does not influence Schwann cell proliferation after rat sciatic nerve transection. Brain Res 654:303-311.
30. Trachtenberg JT, Thompson WJ (1996): Schwann cell apoptosis at developing neuromuscular junctions is regulated by glial growth factor. Nature 379:174-177.
31. Tzahar E, Levkowitz G, Karunagaran D, Yi L, Peles E, Lavi S, Chang D, Liu N, Yayon A, Wen D, Yarden Y (1994): ErbB-3 and erbB-4 function as the respective low and high affinity receptors of all neu differentiation factor/heregulin isoforms. J Biol Chem 269(40):25226-25233.
32. Tzeng S-F, Deibler GE, Neuberger TJ, DeVries GH (1995): Two mitogenic regions of myelin basic protein interact with different receptors to induce Schwann cell proliferation in a cAMP dependent process. J Neurosci Res 42:758-767.
33. Ullrich A, Schlessinger J (1990): Signal transduction by receptors with tyrosine kinase activity. Cell 61:203-212.
34. Vartanian T, Corfas G, Li Y, Fischbach GD, Stefansson K (1994): A role for the acetylcholine receptor-inducing protein ARIA in oligodendrocyte development. Proc Natl Acad Sci USA 91:11626-11630.
35. Wen D, Suggs SV, Karunagaran D, Liu N, Cupples RL, Luo Y, Janssen AM, Ben-Baruch N, Trollinger DB, Jacobsen VL, Meng S-Y, Lu HS, Hu S, Chang D, Yang W, Yanigahara D, Koski RA, Yarden Y (1994): Structural and functional aspects of the multiplicity of neu differentiation factors. Mol Cell Biol 14:1909-1919.