Cell type-specific regulation of β2-adrenoceptor mRNA by agonists

European Journal of Pharmacology

Volumn 331, Issue 1, 1997, Pages 73-78

  Danner, Stefan ^a   Lohse, Martin J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

2 Adrenoceptor; mRNA half life; Receptor down regulation

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; MESSENGER RNA; PROTEIN SYNTHESIS INHIBITOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CONTROLLED STUDY; GLIOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SMOOTH MUSCLE FIBER; TISSUE SPECIFICITY;

ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, NORTHERN; CELL CYCLE; CELL LINE; CRICETINAE; DOWN-REGULATION; EXOTOXINS; GENE EXPRESSION REGULATION; ISOPROTERENOL; POLYMERASE CHAIN REACTION; PROTEIN SYNTHESIS INHIBITORS; RADIOLIGAND ASSAY; RATS; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0030822882     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01022-4     Document Type: Article

References (26)

1. 2-adrenergic receptor regulation after transfection into a cell line deficient in the cAMP-dependent protein kinase. Mol. Pharmacol. 36, 248-255.
2. 2-adrenergic receptor mRNA 3′-unlranslaled region. J. Cell. Physiol. 157, 70-76.
3. 2-adrenergic receptor. J. Biol. Chem. 264, 16786-16792.
4. Chomczynski, P., 1992. One-hour downward alcaline capillary transfer for blotting of DNA and RNA. Anal. Biochem. 201, 134-139.
5. Chomczynski, P., Sacchi, N., 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
6. 2-adrenergic receptor gene in response to short-term agonist exposure. Proc. Natl. Acad. Sci. USA 86, 4853-4857.
7. 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP. J. Biol. Chem. 265, 19330-19335.
8. Collins, S., Caron, M.G., Lefkowitz, R.J., 1991. Regulation of adrenergic receptor responsiveness through modulation of receptor gene expression. Annu. Rev. Physiol. 53, 497-508.
9. Danner, S., Lohse, M.J., 1996. Phosducin is a ubiquitous G-protein regulator. Proc. Natl. Acad. Sci. USA 93, 10145-10150.
10. Engelhardt, S., Böhm, M., Erdmann, E., Lohse, M.J., 1996. Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: Progressive reduction of betal-adrenergic receptor mRNA in heart failure. J. Am. Coll. Cardiol. 27, 146-154.
11. 2-adrenoceptor disrupt multiple receptor functions. Eur. J. Pharmacol. 307, 243-250.
12. Hadcock, J.R., Wang, H.Y., Malbon, C.C., 1989. Agonist-induced destabilization of β-adrenergic receptor mRNA. J. Biol. Chem. 264, 19928-19933.
13. Hadcock, J.R., Malbon, C.C., 1993. Agonist regulation of gene expression of adrenergic receptors and G-proteins. J. Neurochem. 60, 1-9.
14. Hausdorff, W.P., Caron, M.G., Lefkowitz, R.J., 1990. Turning off the signal: Desensitization of β-adrenergic receptor function. FASEB J. 4, 2881-2889.
15. 2-adrenergic receptor mRNA and gene transcription in rat C6 glioma cells: Effects of agonist, forskolin and protein synthesis inhibition. Mol. Pharmacol. 48, 206-211.
16. 2-adrenergic receptor mRNA in C6 glioma cells. Biochem. Biophys. Res. Commun. 170, 46-52.
17. Lohse, M.J., 1993. Molecular mechanisms of membrane receptor desensitization. Biochim. Biophys. Acta 1179, 171-188.
18. 2-adrenergic receptor mRNA inhibits receptor synthesis. J. Biol. Chem. 269, 4497-4505.
19. Pende, A., Tremmel, K.D., DeMaria, C.T., Blaxall, B.C., Minobe, W.A., Sherman, J.A., Bisognano, J.D., Bristow, M.R., Brewer, G., Port, J.D., 1996. Regulation of the mRNA-binding protein AUF1 by activation of the β-adrenergic receptor signal transduction pathway. J. Biol. Chem. 271, 8493-8501.
20. I 35,000 protein(s) that selectively binds to β-adrenergic receptor mRNAs. J. Biol. Chem. 267, 24103-24108.
21. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Habor Laboratory, Cold Spring Habor, NY.
22. Schleifer, L.S., Black, I.B., Reid, L.M., 1989. Regulation of beta-adrenergic receptor expression in the liver. J. Cell. Physiol. 140, 52-58.
23. Su, Y.F., Harden, T.K., Perkins, J.P., 1980. Catecholamine-specific desensitization of adenylate cyclase. J. Biol. Chem. 255, 7410-7419.
24. Szentendrei, T., Lazar-Wesley, E., Nakane, T., Virmani, M., Kunos, G., 1992. J. Cell. Physiol. 152, 478-485.
25. 1-adrenergic receptors in the failing human heart. Circulation 87, 454-463.
26. Ungerer, M., Parruti, G., Böhm, M., Puzicha, M., DeBlasi, A., Erdmann, E., Lohse, M.J., 1994. Expression of β-arrestins and β-adrenergic receptor kinases in the failing human heart. Circ. Res. 74, 206-213.