Genetic differences in alcohol drinking preference between inbred strains of mice

Pharmacogenetics

Volumn 7, Issue 3, 1997, Pages 223-233

  He, Xing Xuan ^a   Nebert, Daniel W ^a   Vasiliou, Vasilis ^a,b   Zhu, Huan ^a   Shertzer, Howard G ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Acetaldehyde; Alcohol; Aromatic hydrocarbon receptor; Catalase; Inbred mice

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACETALDEHYDE; AMINOTRIAZOLE; AROMATIC HYDROCARBON RECEPTOR; CATALASE; DISULFIRAM;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRINKING BEHAVIOR; HEREDITY; INBRED STRAIN; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STRAIN DIFFERENCE;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALCOHOL DETERRENTS; ALCOHOL DRINKING; AMITROLE; ANIMALS; BRAIN; CATALASE; DISULFIRAM; ETHANOL; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; TETRACHLORODIBENZODIOXIN;

ANIMALIA;

EID: 0030822763     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199706000-00007     Document Type: Article

References (66)

1. Aebi H. Catalase in vitro. Methods Enzymol 1984: 84, 121-126.
2. Algar EM, Holmes RS. Liver cytosolic aldehyde dehydrogenases from 'alcohol-drinking' and 'alcohol-avoiding' mouse strains: Purification and molecular properties. Int J Biochem 1986: 18, 49-56.
3. Aragon CM, Amit Z. The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption: evidence for brain catalase involvement in the mechanism of action. Neuropharmacology 1992: 31, 709-712.
4. Aragon CM, Amit Z. Differences in ethanol-induced behaviors in normal and acatalasemic mice: systematic examination using a biobehavioral approach. Pharmacol Biochem Behav 1993: 44, 547-554.
5. Aragon CMG, Spivak K, Amit Z. Blockade of ethanol-induced conditioned taste aversion by 3-amino-1,2,4-triazole: evidence for catalase mediated synthesis of acetaldehyde in rat brain. Life Sci 1985: 37, 2077-2084.
6. Aragon CM, Spivak K, Amit Z. Effect of 3-amino-1,2,4-triazole on ethanol-induced narcosis, lethality and hypothermia in rats. Pharmacol Biochem Behav 1991a: 39, 55-59.
7. Aragon CM, Stotland LM, Amit Z. Studies on ethanol-brain catalase interaction: evidence for central ethanol oxidation. Alcohol Clin Exp Res 1991b: 15, 165-169.
8. 2 system. Biochem Pharmacol 1992: 44, 93-98.
9. Berger D, Weiner H. Effects of disulfiram and chloral hydrate on the metabolism of catecholamines in rat liver and brain. Biochem Pharmacol 1977: 26, 741-747.
10. Bigelow SW, Collins AC, Nebert DW. Selective mouse breeding for short ethanol sleep time has led to high levels of hepatic aromatic hydrocarbon (Ah) receptor. Biochem Pharmacol 1989: 38, 3565-3572.
11. Birnbaum LS. The mechanism of dioxin toxicity: relationship to risk assessment. Environ Health Perspect 1994: 102, 157-167
12. Bond SL, Singh SM. Studies with cDNA probes on the in vivo effect of ethanol on expression of the genes of alcohol metabolism. Alcohol & Alcoholism 1990: 25, 385-394.
13. Brady JF, Niao F, Wang MH, Li Y, Ning SM, Gapac JM, Yang CS. Effects of disulfiram on hepatic P450IIE1, other microsomal enzymes, and hepatotoxicity in rats. Toxicol Appl Pharmacol 1991: 108, 366-373.
14. Casini A, Cunningham M, Rojkind M, Lieber CS. Acetaldehyde increases procollagen type 1 and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991: 13, 758-765.
15. Chang C-Y, Smith DR, Prasad VS, Sidman CL, Nebert DW, Puga A. Ten nucleotide differences, five of which cause amino acid changes, are associated with the Ah receptor locus polymorphism of C57BL/6 and DBA/2 mice. Pharmacogenetics 1993: 3, 312-321.
16. Cohen G, Sinet PM, Heikkila R. Ethanol oxidation by rat brain in vivo. Alcohol Clin Exp Res 1980: 4, 366-370.
17. Crabbe JC, Belknap JK, Buck KJ. Genetic animal models of alcohol and drug abuse. Science 1994: 264, 1715-1723.
18. 1B serotonin receptors. Nature Genet 1996: 14, 98-101.
19. De Waele J-P, Papachristou DN, Gianoulakis C. The alcohol-preferring C57BL/6 mice present an enhanced sensitivity of the hypothalmic β-endorphin system to ethanol than the alcohol-avoiding DBA/2 mice. J Pharmacol Exp Ther 1992: 261, 788-794.
20. Eriksson CJP. The aversive effect of acetaldehyde on alcohol drinking behavior in the rat. Alcohol Clin Exp Res 1980: 4, 107-111.
21. Eriksson CJP, Mizoi Y, Fukunaga T. The determination of acetaldehyde in human blood by the perchloric acid precipitation method: The characterization and elimination of artifactual acetaldehyde formation. Anal Biochem 1982: 125, 259-263.
22. 6-methylguanine transferase. Carcinogenesis 1988: 9, 761-766.
23. Fried R. Biochemical actions of anti-alcoholic agents. Subst Alc Actions/Misuse 1980: 1, 5-27.
24. Froehlich JC, Harts J, Lumeng L, Li T-K. Naloxone attenuates voluntary ethanol intake in rats selectively bred for high ethanol preference. Pharmacol Biochem Behav 1990: 35, 385-390.
25. Gill K, Menez JF, Lucas D, Deitrich RA. Enzymatic production of acetaldehyde from ethanol in rat brain tissue. Alcohol Clin Exp Res 1992: 16, 910-915.
26. Goldman D. Why mice drink. Nature Genet 1996: 13, 137-138.
27. Goldman D, Lister RG, Crabbe JC. Mapping of a putative genetic locus determining ethanol intake in the mouse. Brain Res 1987: 420, 220-226.
28. Goldstein M, Anagnoste B, Lauber E, McKereghan MR. Inhibition of dopamine-β-hydroxylase by disulfiram. Life Sci 1964: 3, 763-767.
29. Gonzalez FJ, Skoda R, Hardwick JP, Song BJ, Umeno M, McBride OW, Kozak C, Matsunaga E, Matsunaga T, Kimura S et al. Human and rat debrisoquine 4-hydroxylase and ethanol-inducible P-450 gene families: structure, regulation and polymorphisms. In: Miners J, Birkett DJ, Drew R, McManus M, eds. Microsomes and Drug Oxidations. New York: Taylor and Francis, 1987: 209-215.
30. Gora-Maslak G, McClearn GE, Crabbe JC, Phillips TJ, Belknap JK, Plomin R. Use of recombinant inbred strains to identify quantitative trait loci in psychopharmacology. Psychopharmacology 1991: 104, 413-424.
31. Hart BW, Faiman MD. In vitro and in vivo inhibition of rat liver aldehyde dehydrogenase by S-methyl N,N-diethylthiolcarbamate sulfoxide, a new metabolite of disulfiram. Biochem Pharmacol 1992: 43, 403-406.
32. Helander A, Tottmar O. Effects of disulfiram, cyanamide and 1-aminocyclopropanol on the aldehyde dehydrogenase activity in human erythrocytes and leukocytes. Pharmacol & Toxicol 1988: 63, 262-265.
33. Helander A, Löwenmo C, Johansson M. Distribution of acetaldehyde in human blood: effects of ethanol and treatment with disulfiram. Alcohol & Alcoholism 1993: 28, 461-468.
34. Hellström E, Tottmar O. Effects of aldehyde dehydrogenase inhibitors on enzymes involved in the metabolism of biogenic aldehydes in rat liver and brain. Biochem Pharmacol 1982: 31, 3899-3905.
35. Hilton ME. Drinking patterns and drinking problems in 1984: Results from a general population survey. Alcohol Clin Exp Res 1987: 11, 167-175.
36. Keller M. A historical overview of alcohol and alcoholism. Cancer Res 1979: 39, 2822-2829.
37. Keung W-M, Vallee BL. Therapeutic lessons from traditional oriental medicine to contemporary occidental pharmacology. In: Jansson B, Jörnvall H, Rydberg U, Terenius L, Vallee BL, eds. Toward a Molecular Basis of Alcohol Use and Abuse. Basel, Switzerland: Birkhäuser Verlag, 1994.
38. Kitson TM. The effect of disulfiram on the aldehyde dehydrogenases of sheep liver. Biochem J 1975: 151, 407-412.
39. Koechling UM, Amit Z. Effects of 3-amino-1,2,4-triazole on brain catalase in the mediation of ethanol consumption in mice. Alcohol 1994: 11, 235-239.
40. Koivisto T, Eriksson CJ. Hepatic aldehyde and alcohol dehydrogenases in alcohol-preferring and alcohol-avoiding rat lines. Biochem Pharmacol 1994: 48, 1551-1558.
41. Lahti RA, Majchrowicz E. Acetaldehyde - an inhibitor of the metabolic oxidation of 5-hydroxyindoleacetaldehyde. Biochem Pharmacol 1969: 18, 535-538.
42. Li T-K, Lumeng L. Alcohol preference and voluntary alcohol intakes of inbred rat strains and the National Institutes of Health heterogenous stock of rats. Alcohol Clin Exp Res 1984: 8, 485-492.
43. Li T-K, Lumeng L, McBride WJ, Waller MB. Progress toward a voluntary oral consumption model of alcoholism. Drug Alcohol Depend 1979: 4, 45-60.
44. Li TK, Lumeng L, McBride WJ, Murphy JM. Genetic and neurobiological basis of alcohol-seeking behavior. Alcohol & Alcoholism 1994: 29, 697-700.
45. McBride WJ, Murphy JM, Lumeng L, Li T-K. Effects of Ro 15-4513, fluoxetine and desipramine on the intake of ethanol, water and food by the alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacol Biochem Behav 1988: 30, 1045-1050.
46. Martini R, Ingelman-Sundberg M, Murray M. Pretranslational and posttranslational regulation of rat hepatic CYPs 3A2 and 2E1 by disulfiram. Biochem Pharmacol 1997 (In press).
47. Melo JA, Shendure J, Pociask K, Silver LM. Identification of sex-specific quantitative trait loci controlling alcohol preference in C57BL/6 mice. Nature Genet 1996: 13, 147-153.
48. Nebert DW. Pharmacogenetics: An approach to understanding chemical and biological aspects of cancer. J Natl Cancer Inst 1980: 64, 1279-1290.
49. Nebert DW. The Ah locus: genetic differences in toxicity, cancer, mutation, and birth defects. CRC Crit Rev Toxicol 1989: 20, 153-174.
50. Nebert DW. Drug metabolism and signal transduction: Possible role of Ah receptor and arachidonic acid cascade in protection from ethanol toxicity. In: Jansson B, Jörnvall H, Rydberg U, Terenius L, Vallee BL, eds. Toward a Molecular Basis of Alcohol Use and Abuse. Basel, Switzerland: Birkhäuser Verlag, 1994: 231-240.
51. Nebert DW, Gonzalez FJ. P450 genes: structure, evolution, and regulation. Annu Rev Biochem 1987: 56, 945-993.
52. Nebert DW, Puga A, Vasiliou V. Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction. Ann NY Acad Sci 1993: 685, 624-640.
53. Niemelä O, Mannermaa R-M, Oikarinen J. Impairment of histone H1 DNA binding by adduct formation with acetaldehyde. Life Sci 1990: 47, 2241-2249.
54. Peterson CM, Scott BK. Studies of whole blood-associated acetaldehyde as a marker for alcohol intake in mice. Alcohol Clin Exp Res 1989: 13, 845-848.
55. Phillips TJ, Crabbe JC, Metten P, Belknap JK. Localization of genes affecting alcohol drinking in mice. Alcohol Clin Exp Res 1994: 18, 931-941.
56. 1450 formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice genetically 'non-responsive' to other aromatic hydrocarbons. J Biol Chem 1974: 249, 5599-5606.
57. Segal HL, Matsuzawa T. L-alanine aminotransferase (rat liver). Methods Enzymol 1970: 17, 153-163.
58. Shertzer HG, Salisbury M. Intrinsic acute toxicity and hepatic enzyme inducing properties of the chemoprotectants indole-3-carbinol and 5,10-dihydroindeno[1,2-b]indole in mice. Fd Chem Toxicol 1991: 29, 237-242.
59. Tampier L, Quintanilla ME, Mardones J. Acetaldehyde metabolism: differences between UChA and UChB rats. Alcohol & Alcoholism 1994: 29, 751-755.
60. Terelius Y, Norsten-Hoog C, Cronholm T, Ingelman-Sundberg M. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1). Biochem Biophys Commun 1991: 179, 689-694.
61. Uppal R, Lateef SK, Korsten MA, Paronetto F, Lieber CS. Chronic alcoholic gastritis. Roles of alcohol and Helicobacter pylori. Arch Int Med 1991: 151, 760-764.
62. Vasiliou V, Malamas M, Marselos M. The mechanism of alcohol intolerance produced by various therapeutic agents. Acta Pharmacol Toxicol 1986: 58, 305-310.
63. Vasiliou V, Reuter SF, Kozak CA, Nebert DW. Mouse class 3 aldehyde dehydrogenases. Adv Exp Med Biol 1995: 372, 151-158.
64. York JL. Consumption of intoxicating beverages by rats and mice exhibiting high and low preferences for ethanol. Pharmacol Biochem Behav 1981: 15, 207-214.
65. Yoshimoto K, Komura S. Reexamination of the relationship between alcohol preference and brain monoamines in inbred strains of mice including senescence-accelerated mice. Pharmacol Biochem Behav 1987: 27, 317-322.
66. Yoshimoto K, Komura S, Kawamura K. Occurrence in vivo of 5-hydroxytryptophol in the brain of rats treated with ethanol. Alcohol & Alcoholism 1992: 27, 131-136.