Role of nitric oxide in retinal cell death

Clinical Neuroscience

Volumn 4, Issue 5, 1997, Pages 216-223

  Roth, Steven ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Circulation; Glutamate; Ischemia; Nitric oxide; Retinal

Indexed keywords

ANTIOXIDANT; ARGININE; ASPARTIC ACID; CYTOKINE; EXCITATORY AMINO ACID; FREE RADICAL; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID; N(G) METHYLARGININE; N(G) NITROARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CAT; CELL DEATH; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOSE RESPONSE; ENZYME LOCALIZATION; ENZYME POLYMORPHISM; EYE PROTECTION; HUMAN; HUMAN TISSUE; INTRAVENOUS DRUG ADMINISTRATION; NEUROTOXICITY; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; REPERFUSION INJURY; RETINA BIPOLAR GANGLION CELL; RETINA BLOOD FLOW; RETINA BLOOD VESSEL OCCLUSION; RETINA ISCHEMIA; REVIEW; THROMBOCYTE AGGREGATION;

ANIMALS; APOPTOSIS; CELL DEATH; HUMANS; ISCHEMIA; NITRIC OXIDE; RETINA; RETINAL VESSELS;

EID: 0030820926     PISSN: 10656766     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (98)

1. Anderson DR, Davis EB (1975): Sensitivities of ocular tissues to acute pressure-induced ischemia. Arch Ophthalmol 93:267-274.
2. Beckman JS (1991): The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J Dev Physiol 15:53-59.
3. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA (1990): Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87:1620-1624.
4. Blough NV, Zafiriou OC (1985): Reaction of superoxide with nitric oxide to form peroxynitrite in alkaline aqueous solution. Inorg Chem 24:3504-3505.
5. Bredt DS, Snyder SH (1989): Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 86:9030-9033.
6. Bredt DS, Snyder SH (1992): Nitric oxide: A novel neuronal messenger. Neuron 8: 3-11.
7. Bredt DS, Hwang PM, Snyder SH (1990): Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347:768-770.
8. Chakravarthy U, Stitt AW, McNally J, Bailie JR, Hoey EM, Duprex P (1995): Nitric oxide synthase activity and expression in retinal capillary endothelial cells and pericytes. Curr Eye Res 14:285-294.
9. Choi DW (1987): Ionic dependence of glutamate neurotoxicity. J Neurosci 7:369-379.
10. Choi DW (1990): Glutamate neurotoxicity: A three-stage process. In Guidotti A (ed): Neurotoxicity of Excitatory Amino Acids. FIDIA Research Foundation Symposium Series. New York: Raven Press, pp 235-242.
11. Dawson TM, Snyder SH (1994): Gases as biological messengers: Nitric oxide and carbon monoxide in the brain. J Neurosci 14:5147-5159.
12. Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH (1991a): Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc Natl Acad Sci USA 88:7797-7801.
13. Dawson VL, Dawson TM (1995): Physiological and toxicological actions of nitric oxide in the central nervous system. Adv Pharmacol 34:323-342.
14. Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH (1993): Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 13: 2651-2661.
15. Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH (1991b): Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88:6368-6371.
16. Deussen A, Sonntag M, Vogel R (1993): L-arginine-derived nitric oxide: A major determinant of uveal blood flow. Exp Eye Res 57:129-134.
17. Dighiero P, Reux I, Hauw JJ, Fillet AM, Courtois Y, Goureau O (1994): Expression of inducible nitric oxide synthase in cytomegalovirus-infected glial cells of retinas from AIDS patients. Neurosci Lett 166:31-34.
18. Donati G, Pournaras CJ, Munoz J-L, Poitry S, Poitry-Yamate CL, Tsacopoulos M (1995): Nitric oxide controls arteriolar tone in the retina of the miniature pig. Invest Ophthalmol Vis Sci 36:2228-2237.
19. Endoh M, Maiese K, Wagner J (1994): Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res 651:92-100.
20. Faraci FM, Brian JE (1994): Nitric oxide and the cerebral circulation. Stroke 25:692-703.
21. Flügel C, Tamm ER, Mayer B, LütjenDrecoll E (1994): Species differences in choroidal vasodilative innervation: Evidence for specific intrinsic nitrergic and VIP-positive neurons in the human eye. Invest Ophthalmol Vis Sci 35:592-599.
22. Garthwaite J, Charles SL, Chess-Williams R (1988): Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 336:385-388.
23. Garthwaite J, Garthwaite G, Palmer RMJ, Moncada S (1989): NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 172:413-416.
24. Geyer O, Almog J, Lupu-Meiri M, Lazar M, Oron Y (1995): Nitric oxide synthase inhibitors protect rat retina against ischemic injury. FEBS Lett 374:399-402.
25. Gidday JM, Zhu Y (1995): Nitric oxide does not mediate autoregulation of retinal blood flow in newborn pig. Am J Physiol 269:H1065-H1072.
26. Goureau O, Hicks D, Courtois Y, De Kozak Y (1994a): Induction and regulation of nitric oxide synthase in retinal Müller glial cells. J Neurochem 63:310-317.
27. Goureau O, Bellot J, Thillaye B, Courtois Y, De Kozak Y (1995a): Increased nitric oxide production in endotoxin-induced uveitis: Reduction of uveitis by an inhibitor of nitric oxide synthase. J Immunol 154:6518-6523.
28. Goureau O, Faure V, Courtois Y (1995b): Fibroblast growth factors decrease inducible nitric oxide synthase mRNA accumulation in bovine retinal pigmented epithelial cells. Eur J Biochem 230:1046-1052.
29. Goureau O, Hicks D, Courtois Y (1994b): Human retinal pigmented epithelial cells produce nitric oxide in response to cytokines. Biochem Biophys Res Commun 198:120-126.
30. Goureau O, Lepoivre M, Becquet F, Courtois Y (1993): Differential regulation of inducible nitric oxide synthase by fibroblast growth factors and transforming growth factor β in bovine retinal pigmented epithelial cells: Inverse correlation with cellular proliferation. Proc Natl Acad Sci USA 90:4276-4280.
31. Goureau O, Lepoivre M, Courtois Y (1992): Lipopolysaccharide and cytokines induced macrophage-type of nitric oxide synthase in bovine retinal pigmented epithelial cells. Biochem Biophys Res Commun 186:854-859.
32. Guevara-Guzman R, Emson PC, Kendrick KM (1994): Modulation of in vivo striatal transmitter release by nitric oxide and cyclic GMP. J Neurochem 62:807-810.
33. Haefliger IO, Zschauer A, Anderson DR (1994): Relaxation of retinal pericyte contractile tone through the nitric oxidecyclic guanosine monophosphate pathway. Invest Ophthalmol Vis Sci 35:991-997.
34. Haley JE, Wilcox GL, Chapman PF (1992): The role of nitric oxide in hippocampal long-term potentiation. Neuron 8:211-216.
35. Hangai M, Yoshimura N, Mandai M, Honda Y (1994): Nitric oxide synthase (NOS) gene expression after retinal ischemia in rats (abstract). Invest Ophthalmol Vis Sci 35:1642.
36. Huang PL, Dawson TM, Bredt DS, Snyder SH, Fishman MC (1993): Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75:1273-1286.
37. Huang Z, Huang PL, Panahian N, Dalkara T, Fishman MC, Moskowitz MA (1994): Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 265:1883-1885.
38. Iadecola C, Xu X, Zhang F, El-Fakahany EE, Ross ME (1995a): Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia. J Cereb Blood Flow Metab 15: 52-59.
39. Iadecola C, Zhang F, Xu S, Casey R, Ross ME (1995b): Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab 15:378-384.
40. Johnson NF, Foulds WS (1978): The effects of total acute ischaemia on the structure of the rabbit retina. Exp Eye Res 27: 45-59.
41. Jones BE, Cole EA, Bator JM, Berkowitz PA, McDonald TB, Shapiro MJ (1996): Effects of nitric oxide synthase inhibition on oxygen-induced retinopathy in a rat model of retinopathy of prematurity (abstract). Invest Ophthalmol Vis Sci 37:628.
42. Kashii S, Mandai M, Takahashi M, Kikuchi M, Honda Y, Akaike A (1994): Involvement of nitric oxide in glutamate neurotoxicity in cultured retinal neurons (abstract). Invest Ophthalmol Vis Sci 35:164.
43. Kitakaze M, Hori M, Takahashi M, Morioka T, Minamino T, Sato H, Okazaki Y, Inoue M, Kamada T (1993): Superoxide dismutase enhances both adenosine release and coronary hyperemic flow through protection of 5′-nucleotidase against its degradation during reperfusion following ischemia in dogs. Biorheology 30: 359-370.
44. Koistinaho J, Swanson RA, Vente JD, Sagar SM (1993): NADPH-diaphorase (nitric oxide synthase)-reactive amacrine cells of rabbit retina: Putative target cells and stimulation by light. Neuroscience 57: 587-597.
45. Koppenol WH, Moreno JJ, Pryor WA, Ischiropoulos H, Beckman JS (1992): Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide. Chem Res Toxicol 5:834-842.
46. Kostic MM, Schrader J (1992): Role of nitric oxide in reactive hyperemia of the guinea pig heart. Circ Res 70:208-212.
47. Kuo PC, Schroeder RA (1995): The emerging multifaceted roles of nitric oxide. Ann Surg 221:220-235.
48. Kurenny DE, Moroz LL, Turner RW, Sharkey KA, Barnes S (1994): Modulation of ion channels in rod photoreceptors by nitric oxide. Neuron 13:315-324.
49. Kutty RK, Kutty G, Hooks JJ, Wiggert B, Nagineni CN (1995): Transforming growth factor-β inhibits the cytokine-mediated expression of the inducible nitric oxide synthase mRNA in human retinal pigment epithelial cells. Biochem Biophys Res Commun 215:386-393.
50. Lees GJ (1993): The possible contribution of microglia and macrophages to delayed neuronal death after ischemia. J Neurol Sci 114:119-122.
51. Lefer AM, Lefer DJ (1993): Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock. Annu Rev Pharmacol Toxicol 33:71-90.
52. Lipton SA, Rosenberg PA (1994): Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 330:613-622.
53. Lipton SA, Choi Y-B, Pan Z-H, Lei SZ, Chan H-SV, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS (1993): A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364: 626-632.
54. Lonart G, Wang J, Johnson KM (1992): Nitric oxide induces neurotransmitter release from hippocampal slices. Eur J Pharmacol 220:271-272.
55. Lorant DE, Patel KD, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA (1991): Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: A juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 115:223-234.
56. Maynard KI, Yanez P, Ogilvy CS (1995): Nitric oxide modulates light-evoked compound action potentials in the intact rabbit retina. Neuroreport 6:850-852.
57. Morris SM, Billiar TR (1994): New insights into the regulation of inducible nitric oxide synthesis. Am J Physiol 266:E829-E839.
58. Nathan C, Xie Q-W (1994): Regulation of biosynthesis of nitric oxide. J Biol Chem 269:13725-13728.
59. Neal MJ, Cunningham JR, Hutson PH, Hogg J (1994): Effects of ischaemia on neurotransmitter release from the isolated retina. J Neurochem 62:1025-1033.
60. Nelson RJ, Demas GE, Huang PL, Fishman MC, Dawson VL, Dawson TM, Snyder SH (1995): Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature 378:383-386.
61. Olney JW (1982): The toxic effects of glutamate and related compounds in the retina and brain. Retina 2:341-359.
62. Ophir A, Berenshtein E, Kitrossky N, Berman ER, Photiou S, Rothman Z, Chevion M (1993): Hydroxyl radical generation in the cat retina during reperfusion following ischemia. Exp Eye Res 57:351-357.
63. Ostwald P, Goldstein IM, Pachnanda A, Roth S (1995): Effects of nitric oxide synthase inhibition on retinal blood flow and the electroretinogram following retinal ischemia. Invest Ophthalmol Vis Sci 36:2396-2403.
64. Ostwald P, Park SS, Roth S (1997): Adenosine receptor blockade and nitric oxide synthase inhibition in the cat retina: Impact upon post-ischemic hyperemia and the electroretinogram. Vision Res (in press).
65. Park C-S, Pardhasaradhi K, Gianotti C, Villegas E, Krishna G (1994): Human retina expresses both constitutive and inducible isoforms of nitric oxide synthase mRNA. Biochem Biophys Res Commun 205:85-91.
66. Pelligrino DA (1993): Saying NO to cerebral ischemia. J Neurosurg Anesthesiol 5:221-231.
67. Phillis JW (1994): A "radical" view of cerebral ischemic injury. Prog Neurobiol 42:441-448.
68. Rosenbaum PS, Lupu VD, Park SS, Pelligrino DA, Roth S (1996): Nitric oxide synthase inhibition and retinal ischemia (abstract). Invest Ophthalmol Vis Sci 37:675.
69. Roth S (1995): Post-ischemic hyperemia in the retina: The effect of adenosine receptor blockade. Curr Eye Res 14:323-328.
70. Roth S, Pietrzyk Z (1994): Blood flow after retinal ischemia in cats. Invest Ophthalmol Vis Sci 35:3209-3217.
71. Roufail E, Stringer M, Rees S (1995): Nitric oxide synthase immunoreactivity and NADPH diaphorase staining are colocalised in neurons closely associated with vasculature in rat and human retina. Brain Res 684:36-46.
72. Rowe GT, Eaton LR, Hess ML (1984): Neutrophil-derived oxygen free radical mediated cardiovascular dysfunction. Cell Cardiol 6:1075-1079.
73. Samuni A, Black CDV, Krishna CM, Malech HL, Bernstein EF, Russo A (1988): Hydroxyl radical production by stimulated neutrophils reappraised. J Biol Chem 263:13797-13801.
74. Schousboe A (1981): Transport and metabolism of glutamate and GABA in neurons and glial cells. Int Rev Neurobiol 22: 1-45.
75. G-nitro-L-arginine methyl ester on the cardiovascular system of the anaesthetized rabbit and on the cardiovascular response to thyrotropin-releasing hormone. Br J Pharmacol 109:1219-1225.
76. Shakib M, Ashton N (1966): Part II. Ultrastructural changes in focal retinal ischemia. Br J Ophthalmol 50:325-354.
77. Snodderly DM (1995): Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 62:14485-1461S.
78. Snyder SH, Bredt DS (1992): Biological roles of nitric oxide. Sci Am 266:68-77.
79. Stamler JS, Singel DJ, Loscalzo J (1992): Biochemistry of nitric oxide and its redox-activated forms. Science 258:1898-1902.
80. Stewart AG, Phan LH, Grigoriadis G (1994): Physiological and pathophysiological roles of nitric oxide. Microsurgery 15: 693-702.
81. Szabo M, Dray-Lefaix M, Daly M, Carre C, Braquet P (1991): Ischemia and reperfusion-induced histologic changes in the rat retina. Demonstration of a free radical-mediated mechanism. Invest Ophthalmol Vis Sci 32:1471-1478.
82. Tilton RG, Chang K, Hasan KS, Smith SR, Petrash JM, Misko TP, Moore WM, Currie MG, Corbett JA, McDaniel ML, Williamson JR (1993): Prevention of diabetic vascular dysfunction by guanidines: Inhibition of nitric oxide synthase versus advanced glycation end-product formation. Diabetes 42:221-232.
83. Toda N, Kitamura Y, Okamura T (1994): Role of nitroxidergic nerve in dog retinal arterioles in vivo and arteries in vitro. Am J Physiol 266:H1985-H1992.
84. Traystman RJ, Kirsch JR, Koehler RC (1991): Oxygen free radical mechanisms of brain injury following ischemia and reperfusion. J Appl Physiol 71:1185-1195.
85. Tsukahara Y, Blair NP, Spellman-Eappen DC, Moy JJ, Takahashi A, Shah GK, Viana MAG (1992): Ketamine suppresses ischemic injury in the rabbit retina. Invest Ophthalmol Vis Sci 33: 1822-1825.
86. Ujihara H, Akaike A, Tamura Y, Yokota T, Sasa M, Kashii S, Honda Y (1993): Blockade of retinal NMDA receptors by sodium nitroprusside is probably due to nitric oxide formation. Jpn J Pharmacol 61:375-377.
87. Veriac S, Tissie G, Bonne C (1993): Oxygen free radicals adversely affect the regulation of vascular tone by nitric oxide in rabbit retina under high intraocular pressure. Exp Eye Res 56:85-88.
88. Vincent SR, Hope BT (1992): Neurons that say NO. Trends Neurosci 15:108-113.
89. Wiencke AK, Nilsson H, Nielson PJ, Nyborg NCBB (1994): Nonadrenergic noncholinergic vasodilation in bovine ciliary artery involves CGRP and neurogenic nitric oxide. Invest Ophthalmol Vis Sci 35:3268-3277.
90. Wilson CA, Hatchell DL (1991): Photodynamic retinal vascular thrombosis: Rate and duration of vascular occlusion. Invest Ophthalmol Vis Sci 32:2357-2365.
91. Yamamoto R, Bredt DS, Dawson TM, Snyder SH, Stone RA (1993a): Enhanced expression of nitric oxide synthase by rat retina following pterygopalatine parasympathetic denervation. Brain Res 631:83-88.
92. Yamamoto R, Bredt DS, Snyder SH, Stone RA (1993b): The localization of nitric oxide synthase in the rat eye and related cranial ganglia. Neuroscience 54;189-200.
93. Yao K, Tschudi M, Flammer J, Lüscher TF (1991): Endothelium-dependent regulation of vascular tone of the porcine ophthalmic artery. Invest Ophthalmol Vis Sci 32:1791-1798.
94. Yoon YH, Marmor MF (1989): Dextromethorphan protects retina against ischemic injury in vivo. Arch Ophthalmol 107: 409-411.
95. Zagvazdin YS, Fitzgerald MEC, Sancesario G, Reiner A (1996): Neural nitric oxide mediates Edinger-Westphal nucleus evoked increase in choroidal blood flow in the pigeon. Invest Ophthalmol Vis Sci 37:666-672.
96. Zeevalk GD, Nicklas WJ (1990): Chemically induced hypoglycemia and anoxia: Relationship to glutamate receptor-mediated toxicity in retina. J Pharmacol Exp Ther 253:1285-1292.
97. Zeevalk GD, Nicklas WJ (1994): Nitric oxide in retina: Relation to excitatory amino acids and excitotoxicity. Exp Eye Res 58:343-350.
98. Zeevalk GD, Hyndman AG, Nicklas WJ (1989): Excitatory amino acid-induced toxicity in chick retina: Amino acid release, histology, and the effects of chloride channel blockers. J Neurochem 53:1610-1619.