Neural nitric oxide mediates Edinger-Westphal nucleus evoked increase in choroidal blood flow in the pigeon

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 4, 1996, Pages 666-672

  Zagvazdin, Yuri S ^a   Fitzgerald, Malinda E C ^a   Sancesario, Giuseppe ^b   Reiner, Anton ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

7 NITROINDAZOLE; ARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN NUCLEUS; CHOROID; CILIARY GANGLION; CONTROLLED STUDY; EYE BLOOD FLOW; NONHUMAN; PIGEON; PRIORITY JOURNAL; VASODILATATION;

ANIMALS; ARGININE; BLOOD PRESSURE; CHOROID; COLUMBIDAE; ELECTRIC STIMULATION; ENZYME INHIBITORS; GANGLIA, PARASYMPATHETIC; INDAZOLES; LASER-DOPPLER FLOWMETRY; NEURONS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OCULOMOTOR NERVE; REGIONAL BLOOD FLOW;

EID: 0030005078     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Forstermann U, Pollock JS, Nakane M. Nitric oxide synthases in the cardiovascular system. Trends Cardiovasc Med. 1993;3:104-110.
2. Mann RM, Riva CE, Stone RA, Barnes GE, Cranstoun SD. Nitric oxide and choroidal blood flow regulation. Invest Ophthalmol Vis Sci. 1995;36:925-930.
3. Deussen A, Sonntag M, Vogel R. L-arginine-derived nitric oxide: A major determinant of uveal blood flow. Exp Eye Res. 1993;57:129-134.
4. Reiner A, Karten HJ, Gamlin PDR, Erichsen JT. Parasympathetic ocular control. Functional subdivision and circuitry of the avian nucleus of Edinger-Westphal. Trends Neurosci. 1983;6:140-145.
5. Sun W, Erichsen JT, May PJ. NADPH-diaphorase reactivity in ciliary ganglion neurons: A comparison of distributions in pigeon, cat and monkey. Visual Neurosci. 1994;11:1027-1031.
6. Fitzgerald MEC, Reiner A. NADPH-diaphorase positive neurons and fibers in the ciliary ganglion and choroid of the pigeon. Soc Neurosci Abstracts 1993;19:1202.
7. Bergua A, Neuhuber WL, Mayer B. Comparative anatomy of nitrinergic innervation in avian choroid. ARVO Abstracts. Invest Ophthalmol Visual Sci. 1995;36:S121.
8. Zagvazdin Y, Fitzgerald MEC, Sancesario G, Jackson B, Schmidt H, Reiner A. Neural nitric oxide mediates Edinger-Westphal nucleus evoked vasodilation of choroidal vessels in pigeon eye. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1994;35:S1287.
9. Cuthbertson S, Fitzgerald MEC, Shih YF, Toledo CB, Jackson B, Reiner A. Innervation of orbital and choroidal blood vessels by the pterygopalatine ganglion in birds. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1995;36:S121.
10. Yamamoto R, Bredt DS, Snyder SH, Stone RA. The localization of nitric oxide synthase in the rat eye and related cranial ganglia. Neuroscience. 1993;54:189-200.
11. Flugel-Koch C, Kaufman P, Lutjen-Drecoll E. Association of a choroidal ganglion cell plexus with the fovea centralis. Invest Ophthalmol Visual Sci. 1994;35:4268-4272.
12. Moore PK, Wallace P, Gaffen Z, Hart SL, Babbedge RC. Characterization of the novel nitric oxide synthase inhibitor 7-nitroindazole and related indazoles: Antinociceptive and cardiovascular effects. Br J Pharmacol. 1993;110:219-224.
13. Yoshida T, Limmroth V, Irikura K, Moskowitz MA. The NOS inhibitor, 7-Nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab. 1994;14:924-929.
14. Fitzgerald MEC, Vana BA, Reiner A. Control of choroidal blood flow by the nucleus of Edinger-Westphal in pigeons: A laser Doppler study. Invest Ophthalmol Visual Sci. 1990;31:2483-2492.
15. Gherezghiher T, Okubo H, Koss MC. Choroidal and ciliary body blood flow analysis: Application of laser Doppler flowmetry in experimental animals. Exp Eye Res. 1991;53:151-156.
16. Kiel JW, Shepherd AP. Autoregulation of choroidal blood flow in the rabbit. Invest Ophthalmol Vis Sci. 1992;33:2399-2410.
17. MacKenzie GM, Rose S, Bland-Ward PA, Moore PK, Jenner P, Marsden GD. Time course of inhibition of brain nitric oxide synthase by 7-nitro indazole. Neuroreport. 1994;5:1993-1996.
18. Scott TRD, Bennet MR. The effect of nitric oxide on the efficacy of synaptic transmission through the chick ciliary ganglion. Br J Pharmacol. 1993;110:627-632.
19. Gray DB, Scranton V, Pilar GR. Somatostatin inhibits transmitter release via nitric oxide and cGMP-dependent kinase in choroid nerve terminals. Soc Neurosci Abstracts. 1993;19:1177.
20. Wiencke AK, Nilsson H, Nielsen PJ, Nyborg NCB. Noradrenergic noncholinergic vasodilation in bovine ciliary artery involves CGRP and neurogenic nitric oxide. Invest Ophthalmol Visual Sci. 1994;35:3268-3277.
21. Nilsson SFE. Nitric oxide as a mediator of parasympathetic vasodilation in the uvea. ARVO Abstracts. Invest Ophthalmol Visual Sci. 1994;35:1288.