Role of P-selectin in endotoxin-induced uveitis

Investigative Ophthalmology and Visual Science

Volumn 38, Issue 8, 1997, Pages 1610-1618

  Suzuma, Kiyoshi ^a   Mandai, Michiko ^a   Kogishi, Jun Ichi ^a   Tojo, Shinichiro J ^b   Honda, Yoshihito ^a   Yoshimura, Nagahisa ^c  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aqueous humor; Endotoxin induced uveitis; Iris ciliary body; P selectin; Sialyl Lewis X oligosaccharide

Indexed keywords

ENDOTOXIN; PADGEM PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTIC INFILTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; UVEITIS; VASCULAR ENDOTHELIUM;

ANIMALS; AQUEOUS HUMOR; ENDOTHELIUM, VASCULAR; ENDOTOXINS; EYE PROTEINS; IMMUNOENZYME TECHNIQUES; IRIS; LIPOPOLYSACCHARIDES; MALE; MICROCIRCULATION; OSMOLAR CONCENTRATION; P-SELECTIN; RATS; RATS, INBRED LEW; TIME FACTORS; UVEITIS;

EID: 0030816704     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Bhattacherjee P, Williams RN, Eakins KE. An evaluation of ocular inflammation following the injection of bacterial endotoxin into the rat foot pad. Invest Ophthalmol Vis Sci. 1983;24:196-202.
2. Rosenbaum JT, McDevitt HO, Guss RB, Egbert PR. Endotoxin-induced uveitis in rats as a model for human disease. Nature. 1980;286:611-613.
3. Whitcup SM, DeBarge LR, Rosen H, Nussenblatt RB, Chan CG. Monoclonal antibody against CD11b/GD18 inhibits endotoxin-induced uveitis. Invest Ophthalmol Vis SCi. 1993;34:673-681.
4. Whitcup SM, Hikita N, Shirao M, et al. Monoclonal antibodies against CD54 (ICAM-1) and CD11a (LFA1) prevent and inhibit endotoxin-induced uveitis. Exp Eye Res. 1995;60:597-601.
5. Rosenbaum JT, Boney RS. Efficacy of antibodies to adhesion molecules, CD11a or GD18, in rabbit models of uveitis. Curr Eye Res. 1993;12:827-831.
6. Ley K, Gaehtgens P, Fennie C, Singer MS, Lasky LA, Rosen SD. Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo. Blood. 1991;77:2553-2555.
7. Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins. Cell 1991;65:859-873.
8. von Andrian UH, Chambers JD, McEvoy LM, Bargatze RF, Arfors KE, Butcher EC. Two-step model of leukocyte-endothelial cell interaction in inflammation: Distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo. Proc Natl Acad Sci USA. 1991;88:7538-7542.
9. Pober JS, Cotran RS. The role of endothelial cells in inflammation. Transplantation. 1990;50:537-544.
10. Butcher EC. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity. Cell. 1991;67:1033-1036.
11. Springer TA. Adhesion receptors of the immune system. Nature. 1990;346:425-434.
12. Zimmerman GA, Prescott SM, McIntyre TM. Endothelial cell interactions with granulocytes: Tethering and signaling molecules. Immunol Today. 1992;13:93-100.
13. Shimizu Y, Newman W, Tanaka Y, Shaw S. Lymphocyte interactions with endothelial cells. Immunol Today. 1992;13:106-112.
14. Bevilacqua MP, Stengelin S, Gimbrone M Jr, Seed B. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science. 1989;243:1160-1165.
15. Bevilacqua MP, Pober JS, Mendrick DL, Cotran RS, Gimbrone M Jr. Identification of an inducible endothelial-leukocyte adhesion molecule. Proc Natl Acad Sci USA. 1987;84:9238-9242.
16. Geng JG, Bevilacqua MP, Moore KL, et al. Rapid neutrophil adhesion to activated endothelium mediated by GMP-140. Nature. 1990;343:757-760.
17. Etingin OR, Silverstein RL, Hajjar DP. Identification of a monocyte receptor on herpesvirus-infected endothelial cells, Proc Natl Acad Sci USA. 1991;88:7200-7203.
18. Toothill VJ, Van Mourik JA, Niewenhuis HK, Metzelaar MJ, Pearson JD, Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells. J Immunol. 1990;145:283-291.
19. Handa K, Nudelman ED, Stroud MR, Shiozawa T, Hakomori S. Selectin GMP-140 (CD62; PADGEM) binds to sialosyl-Le(a) and sialosyl-Le(x), and sulfated glycans modulate this binding. Biochem Biophys Res Commun. 1991;181:1223-1230.
20. Phillips ML, Nudelman E, Gaeta FC, et al. ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. Science. 1990:250:1130-1132.
21. Walz G, Aruffo A, Kolanus W, Bevilacqua M, Seed B. Recognition by ELAM-1 of the sialyl-Lex determinant myeloid and tumor cells. Science. 1990;250:1132-1135.
22. Imai Y, Lasky LA, Rosen SD. Sulphation requirement for GlyCAM-1, an endothelial ligand for L-selectin. Nature. 1993;361:555-557.
23. Baumheter S, Singer MS, Henzel W, et al. Binding of L-selectin to the vascular sialomucin CD34. Science, 1993;262:436-438.
24. Tedder TF, Steeber DA, Chen A, Engel P. The selectins: Vascular adhesion molecules. FASEB J. 1995;9:866-873.
25. Dore M, Korthuis RJ, Granger DN, Entman ML, Smith CW. P-selectin mediates spontaneous leukocyte rolling in vivo. Blood. 1993;82:1308-1316.
26. Mayadas TN, Johnson RC, Rayburn H, Hynes RO, Wagner DD. Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell. 1993;74:541-554.
27. Patel KD, Zimmerman GA, Prescott SM, McEver RP, McIntyre TM. Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils. J Cell Biol. 1991;112:749-759.
28. Hattori R, Hamilton KK, McEver RP, Sims PJ. Complement proteins C5b-9 induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface. J Biol Chem. 1989;264:9053-9060.
29. Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem. 1989;264:7768-7771.
30. McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF. GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular en- dothelial cells and is localized in Weibel-Palade bodies. J Clin Invest. 1989;84:92-99.
31. Bonfanti R, Furie BC, Furie B, Wagner DD. PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells. Blood. 1989;73:1109-1112.
32. Tojo SJ, Yokota S, Koike H, et al. Reduction of rat myocardial ischemia and reperfusion injury by sialyl Lewis x oligosaccharide and anti-rat P-selectin anti-bodies. Glycobiology. 1996;6:463-469.
33. Ohnishi M, Koike H, Kawamura N, Tojo JS, Hayashi M, Morooka S. Role of P-selectin in the early stage of the arthus reaction. Immunopharmacology. 1996;34:161-170.
34. McMenamin PG, Crewe J. Endotoxin-induced uveitis. Kinetics and phenotype of the inflammatory cell infiltrate and the response of the resident tissue macrophages and dendritic cells in the iris and ciliary body. Invest Ophthalmol Vis Sci. 1995;36:1949-1959.
35. McMenamin PG, CreweJ, Morrison S, Holt PG. Immunomorphologic studies of macrophages and MHC class II-positive dendritic cells in the iris and ciliary body of the rat, mouse, and human eye. Invest Ophthalmol Vis Sci. 1994;35:3234-3250.
36. Robinson JM, Batten BE. Detection of diaminobenzidine reactions using scanning laser confocal reflectance microscopy. J Histochem Cytochem. 1989;37:1761-1765.
37. Mulligan MS, Paulson JC, De Frees S, Zheng ZL, Lowe JB, Ward PA. Protective effects of oligosaccharides in P-selectin-dependent lung injury. Nature. 1993;364:149-151.
38. Hoekzema R, Verhagen C, van Haren M, Kijlstra A, Endotoxin-induced uveitis in the rat. The significance of intraocular interleukin-6. Invest Ophthalmol Vis Sci. 1992;33:532-539.
39. Hoekzema R, Murray PI, van Haren MA, Helle M, Kijlstra A. Analysis of interleukin-6 in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1991;32:88-95.
40. Mandai M, Mittag TW, Kogishi J, Iwaki M, Hangai M, Yoshimura N. Role of nitric oxide synthase isozymes in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1996;37:826-832.
41. Whitcup SM, Lobanoff M, Gery I, et al. Role of selectins and integrins in the pathogenesis of endotoxin-induced uveitis (EIU). ARVO Abstracts. Invest Ophthalmol Vis Sci. 1995;36:S385.
42. Tilton RG, Sherwood SJ, Bjercke RJ, et al. Entotoxin-induced leukocyte accumulation in aqueous fluid of rats is decreased by a small molecule selectin antagonist. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1996;37:S918.
43. Suzuma K, Kogishi J, Tojo S, Mandai M, Honda Y, Yoshimura N. The role of P-selectin in endotoxin-in- duced uveitis. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1996;37:S542.
44. Kanwar S, Woodman RC, Poon MC, et al. Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules. Blood, 1995;86:2760-2766.
45. Coughlan AF, Hau H, Dunlop LC, Berndt MC, Hancock WW. P-selectin and platelet-activating factor mediate initial endotoxin-induced neutropenia. J Exp Med. 1994;179:329-334.
46. Nakamura S, Ohtani H, Watanabe Y, et al. In situ expression of the cell adhesion molecules in inflammatory bowel disease. Evidence of immunologic activation of vascular endothelial cells. Lab Invest. 1993;69:77-85.
47. Sanders WE, Wilson RW, Ballantyne CM, Beaudet AL. Molecular cloning and analysis of in vivo expression of murine P-selectin. Blood. 1992;80:795-800.
48. Baatz H, Pleyer U, Thiel HJ, Hammer C. In vivo study of leukocyte-endothelium interaction in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1995;36:1960-1967.
49. Weyrich AS, Buerke M, Albertine KH, Lefer AM. Time course of coronary vascular endothelial adhesion molecule expression during reperfusion of the ischemic feline myocardium. J Leukoc Biol. 1995;57:45-55.
50. Chen LY, Nichols WW, Hendricks JB, Yang BC, Mehta JL. Monoclonal antibody to P-selectin (PB1.3) protects against myocardial reperfusion injury in the dog. Cardiovasc Res. 1994;28:1414-1422.
51. Buerke M, Weyrich AS, Zheng Z, Gaeta FC, Forrest MJ, Lefer AM. Sialyl Lewisx-containing oligosaccharide attenuates myocardial reperfusion injury in cats. J Clin Invest. 1994;93:1140-1148.
52. Lefer DJ, Flynn DM, Phillips ML, Ratcliffe M, Buda AJ. A novel sialyl LewisX analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion. Circulation. 1994;90:2390-2401.
53. Winn RK, Liggitt D, Vedder NB, Paulson JC, Harlan JM. Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J Clin Invest. 1993;92:2042-2047.
54. Mulligan MS, Policy MJ, Bayer RJ, Nunn MF, Paulson JC, Ward PA. Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140). J Clin Invest. 1992;90:1600-1607.
55. Adams RD, Victor M, Ropper AH. Principles of Neurology. 6th ed. New York: McGraw-Hill; 1997:1312-1318.
56. Yoshida M, Yoshimura N, Hangai M, Tanihara H, Honda Y. Interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor gene expression in endotoxin-induced uveitis. Invest Ophthalmol Vis Sci. 1994;35:1107-1113.