메뉴 건너뛰기




Volumn 85, Issue 2, 1997, Pages 195-201

Signals transduced through the CD4 molecule interfere with TCR/ CD3-mediated ras activation leading to T cell anergy/apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; FAS ANTIGEN; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 160; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; TYROSINE;

EID: 0030815339     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1997.4424     Document Type: Article
Times cited : (23)

References (43)
  • 3
    • 0025835006 scopus 로고
    • T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1
    • Secrist, J. P., Karnitz, L., and Abraham, R. T., T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1. J. Biol. Chem. 266, 12135, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12135
    • Secrist, J.P.1    Karnitz, L.2    Abraham, R.T.3
  • 4
    • 0025255387 scopus 로고
    • Transmission of signals from the T lymphocyte antigen receptor to the gene responsible for cell proliferation and immune function: The missing link
    • Ullman, K. S., Norhtrop, J. P., Verweij, C. L., and Crabtree, G. R., Transmission of signals from the T lymphocyte antigen receptor to the gene responsible for cell proliferation and immune function: the missing link. Annu. Reu. Immunol. 8, 421-452, 1990.
    • (1990) Annu. Reu. Immunol. , vol.8 , pp. 421-452
    • Ullman, K.S.1    Norhtrop, J.P.2    Verweij, C.L.3    Crabtree, G.R.4
  • 5
    • 0027207287 scopus 로고
    • Tyrosine kinase stimulated guanine nucleotide exchange activity of vav in T cell activation
    • Gulbins, E., Coggeshall, K M., Gottfried, B., Katzav, S., Burn, P., and Altman, A., Tyrosine kinase stimulated guanine nucleotide exchange activity of vav in T cell activation. Science 260, 822, 1993.
    • (1993) Science , vol.260 , pp. 822
    • Gulbins, E.1    Coggeshall, K.M.2    Gottfried, B.3    Katzav, S.4    Burn, P.5    Altman, A.6
  • 6
    • 0026484267 scopus 로고
    • P21 ras mediates control of IL-2 gene promoter function in T cell activation
    • Rayter, S. I., Woodrow, M., Lucas, S. C., Cantrell, D. A., and Downward, J., p21 ras mediates control of IL-2 gene promoter function in T cell activation. EMBO J. 11, 4549-4556, 1992.
    • (1992) EMBO J. , vol.11 , pp. 4549-4556
    • Rayter, S.I.1    Woodrow, M.2    Lucas, S.C.3    Cantrell, D.A.4    Downward, J.5
  • 7
    • 0028209548 scopus 로고
    • Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
    • Iwashima, M., Irving, B. A., van Oers, N. S. C., Chan, A. C., and Weiss, A., Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 263, 1136-1139, 1994.
    • (1994) Science , vol.263 , pp. 1136-1139
    • Iwashima, M.1    Irving, B.A.2    Van Oers, N.S.C.3    Chan, A.C.4    Weiss, A.5
  • 8
    • 0028168647 scopus 로고
    • Characterization of p59-mediated signal transduction on T cell activation
    • Fusaki, N., Semba, K, Katagiri, T., Suzuki, G., Matsuda, S., and Yamamoto, T., Characterization of p59-mediated signal transduction on T cell activation. Int. Immunol. 6, 1245-1255, 1994.
    • (1994) Int. Immunol. , vol.6 , pp. 1245-1255
    • Fusaki, N.1    Semba, K.2    Katagiri, T.3    Suzuki, G.4    Matsuda, S.5    Yamamoto, T.6
  • 9
    • 0028339169 scopus 로고
    • Vav cooperates with ras to transform rodent fibroblasts but is not a ras GDP/GTP exchange factor
    • Bustelo, X. R., Suen, K. L., Leftheris, K., Meyers, C. A., and Barbacid, M., Vav cooperates with ras to transform rodent fibroblasts but is not a ras GDP/GTP exchange factor. Oncogene 9, 2405-2413, 1994.
    • (1994) Oncogene , vol.9 , pp. 2405-2413
    • Bustelo, X.R.1    Suen, K.L.2    Leftheris, K.3    Meyers, C.A.4    Barbacid, M.5
  • 11
    • 0026669001 scopus 로고
    • Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn
    • Appleby, M.W., Gross, J.A., Cooke, M.P., Levin, S.D., Qian, X., and Perlmutter, R. M., Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70, 751-763, 1992.
    • (1992) Cell , vol.70 , pp. 751-763
    • Appleby, M.W.1    Gross, J.A.2    Cooke, M.P.3    Levin, S.D.4    Qian, X.5    Perlmutter, R.M.6
  • 12
    • 0026612411 scopus 로고
    • Pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
    • Stein, P. L., Lee, H. M., Rich, S., and Soriano, P., pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70, 741-750, 1992.
    • (1992) Cell , vol.70 , pp. 741-750
    • Stein, P.L.1    Lee, H.M.2    Rich, S.3    Soriano, P.4
  • 14
    • 0026164170 scopus 로고
    • The co-receptor function of CD4
    • Janeway, C. A., The co-receptor function of CD4. Semin. Immunol. 3, 153-160, 1991.
    • (1991) Semin. Immunol. , vol.3 , pp. 153-160
    • Janeway, C.A.1
  • 15
    • 0024520882 scopus 로고
    • Identification of the residues in human CD4 critical for binding of human immunodeficiency virus
    • Arthos, J., Deen, C. K., Chaikan, M. A., Fornwald, J. A., Sattentau, Q. J., Clapham, P. R., and Weiss, R. A., Identification of the residues in human CD4 critical for binding of human immunodeficiency virus. Cell 57, 469-481, 1989.
    • (1989) Cell , vol.57 , pp. 469-481
    • Arthos, J.1    Deen, C.K.2    Chaikan, M.A.3    Fornwald, J.A.4    Sattentau, Q.J.5    Clapham, P.R.6    Weiss, R.A.7
  • 16
    • 0024786954 scopus 로고
    • Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: Independence of CD4+ cell numbers and clinical staging
    • Clerici, M., Stocks, N.I., Zajac, R.A., Boswell, R.N., Lucey, D. R., Via, C. S., and Shearer, G. M., Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients: Independence of CD4+ cell numbers and clinical staging. J. Clin. Invest. 84, 1892-1899, 1989.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1892-1899
    • Clerici, M.1    Stocks, N.I.2    Zajac, R.A.3    Boswell, R.N.4    Lucey, D.R.5    Via, C.S.6    Shearer, G.M.7
  • 17
    • 0025058349 scopus 로고
    • Inhibition of functional properties of tetanus antigen specific T cell clones by envelope glycoproteins of HFV-1
    • Chirmule, N., Kalyanaraman, V. S., Oyaizu, N., Slade, H., and Pahwa, S., Inhibition of functional properties of tetanus antigen specific T cell clones by envelope glycoproteins of HFV-1. Blood 75, 152-159, 1990.
    • (1990) Blood , vol.75 , pp. 152-159
    • Chirmule, N.1    Kalyanaraman, V.S.2    Oyaizu, N.3    Slade, H.4    Pahwa, S.5
  • 18
    • 0025218885 scopus 로고
    • Human immunodeficiency virus type 1 envelope glycoprotein gp!20 provides immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA
    • Oyaizu, N., Chirmule, N., Kalyanaraman, V. S., and Pahwa, S., Human immunodeficiency virus type 1 envelope glycoprotein gp!20 provides immune defects in CD4+ T lymphocytes by inhibiting interleukin 2 mRNA. Proc. Natl. Acad. Sei. USA 87, 23792383, 1990.
    • (1990) Proc. Natl. Acad. Sei. USA , vol.87 , pp. 23792383
    • Oyaizu, N.1    Chirmule, N.2    Kalyanaraman, V.S.3    Pahwa, S.4
  • 19
    • 0028785967 scopus 로고
    • Role of apoptosis in HW disease pathogenesis
    • Oyaizu, N., and Pahwa, S., Role of apoptosis in HW disease pathogenesis. J. Clin. Immunol. 15, 217-231, 1995.
    • (1995) J. Clin. Immunol. , vol.15 , pp. 217-231
    • Oyaizu, N.1    Pahwa, S.2
  • 20
    • 0030008309 scopus 로고    scopus 로고
    • Envelope glycoproteins of human immunodeficiency virus type 1: Profound influence on immune functions
    • Chirmule, N., and Pahwa, S., Envelope glycoproteins of human immunodeficiency virus type 1: Profound influence on immune functions. Microbiol. Rev. 60, 386-406, 1996.
    • (1996) Microbiol. Rev. , vol.60 , pp. 386-406
    • Chirmule, N.1    Pahwa, S.2
  • 21
    • 0030838701 scopus 로고    scopus 로고
    • CD4 crosslinking (CD4XL) induces ras activation and TNF-a secretion in CD4+ T cells
    • Lakshmi Tamma, S. M., Chirmule, N., Yagura, H., Oyaizu, N., Kalyanaraman, V. S., and Pahwa, S., CD4 crosslinking (CD4XL) induces ras activation and TNF-a secretion in CD4+ T cells. Blood 90, 1588-1593, 1997.
    • (1997) Blood , vol.90 , pp. 1588-1593
    • Lakshmi Tamma, S.M.1    Chirmule, N.2    Yagura, H.3    Oyaizu, N.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 22
    • 0029118573 scopus 로고
    • HP/-1 envelope glycoproteins induce-activation of activated protein-1 in CD4+ T cells
    • Chirmule, N., Goonewardena, H., Pahwa, S., Pesieka, R., Kalyanaraman, V. S., and Pahwa, S., HP/-1 envelope glycoproteins induce-activation of activated protein-1 in CD4+ T cells. J. Biol. Chem. 270(33), 19364-19369, 1995.
    • (1995) J. Biol. Chem. , vol.270 , Issue.33 , pp. 19364-19369
    • Chirmule, N.1    Goonewardena, H.2    Pahwa, S.3    Pesieka, R.4    Kalyanaraman, V.S.5    Pahwa, S.6
  • 23
    • 0028107790 scopus 로고
    • Signal transduction through the CD4 molecule on T lymphocytes activate NF-K B
    • Chirmule, N., Kalyanaraman, V. S., and Pahwa, S., Signal transduction through the CD4 molecule on T lymphocytes activate NF-K B. Biochem. Biophys. Res. Commun. 203, 498-505, 1994.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 498-505
    • Chirmule, N.1    Kalyanaraman, V.S.2    Pahwa, S.3
  • 25
    • 0030236534 scopus 로고    scopus 로고
    • HIV-1 gp!20 blocks Jacalin-induced proliferative response in CD4+ T cells: Jacalin as a useful surrogate marker for qualitative and quantitative deficiency of CD4+ T cells in HIV-1 infection
    • Lakshmi Tamma, S. M., Oyaizu, N., McCloskey, T. W., Kalyanaraman, V. S., and Pahwa, S., HIV-1 gp!20 blocks Jacalin-induced proliferative response in CD4+ T cells: Jacalin as a useful surrogate marker for qualitative and quantitative deficiency of CD4+ T cells in HIV-1 infection. Clin. Immunol. Immunopathol. 80, 290-329, 1996.
    • (1996) Clin. Immunol. Immunopathol. , vol.80 , pp. 290-329
    • Lakshmi Tamma, S.M.1    Oyaizu, N.2    McCloskey, T.W.3    Kalyanaraman, V.S.4    Pahwa, S.5
  • 26
    • 0028168072 scopus 로고
    • Gp!20 ligation of CD4 induces p561ck activation and TCR desensitization independent of TCR tyrosine phosphorylation
    • Goldman, F., Jensen, W. A., Heasley, L., and Cambier, J. C., gp!20 ligation of CD4 induces p561ck activation and TCR desensitization independent of TCR tyrosine phosphorylation. J. Immunol. 153, 2905-2917, 1994.
    • (1994) J. Immunol. , vol.153 , pp. 2905-2917
    • Goldman, F.1    Jensen, W.A.2    Heasley, L.3    Cambier, J.C.4
  • 27
    • 0028258624 scopus 로고
    • Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes
    • McCloskey, T. W., Oyaizu, N., Coronesi, M., and Pahwa, S., Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes. Clin. Immunol. Immunopathol. 71, 14-18, 1994.
    • (1994) Clin. Immunol. Immunopathol. , vol.71 , pp. 14-18
    • McCloskey, T.W.1    Oyaizu, N.2    Coronesi, M.3    Pahwa, S.4
  • 28
    • 0029041822 scopus 로고
    • Expression of the fas antigen in patients infected with human immunodeficiency virus
    • McCloskey, T. W., Oyaizu, N., Kaplan, M., and Pahwa, S., Expression of the fas antigen in patients infected with human immunodeficiency virus. Cytometry 22, 111-114, 1995.
    • (1995) Cytometry , vol.22 , pp. 111-114
    • McCloskey, T.W.1    Oyaizu, N.2    Kaplan, M.3    Pahwa, S.4
  • 29
    • 0026747810 scopus 로고
    • Role of CD4 molecule in the induction of IL-2 and interleukin 2 receptor in class II major histocompatibility complex-Restricted antigen specific T helper clones
    • Oyaizu, N., Chirmule, N., and Pahwa, S., Role of CD4 molecule in the induction of IL-2 and interleukin 2 receptor in class II major histocompatibility complex-Restricted antigen specific T helper clones. J. Clin. Invest. 89, 1807-1816, 1992.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1807-1816
    • Oyaizu, N.1    Chirmule, N.2    Pahwa, S.3
  • 30
    • 0027960659 scopus 로고
    • Crosslinking of CD4 molecules upregulates fas antigen expression in lymphocytes by inducing interferon gamma and tumor necrosis factor alpha
    • Oyaizu, N., McCloskey, T., Kalyanaraman, V. S., Coronesi, M., and Pahwa, S., Crosslinking of CD4 molecules upregulates fas antigen expression in lymphocytes by inducing interferon gamma and tumor necrosis factor alpha. Blood 84, 2622-2631, 1994.
    • (1994) Blood , vol.84 , pp. 2622-2631
    • Oyaizu, N.1    McCloskey, T.2    Kalyanaraman, V.S.3    Coronesi, M.4    Pahwa, S.5
  • 32
    • 0030001318 scopus 로고    scopus 로고
    • Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
    • Marengere, L. E. M., Waterhouse, P., Duncan, G. S., Hans-Willi Mittrucker, Feng, G.-S., and Mak, T. W., Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science 272, 1170-1173.
    • Science , vol.272 , pp. 1170-1173
    • Marengere, L.E.M.1    Waterhouse, P.2    Duncan, G.S.3    Mittrucker, H.-W.4    Feng5    G-S6    Mak, T.W.7
  • 33
    • 0029328342 scopus 로고
    • Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
    • Karin, M., and Hunter, T., Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr. Biol. 5, 747, 1995.
    • (1995) Curr. Biol. , vol.5 , pp. 747
    • Karin, M.1    Hunter, T.2
  • 34
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and HA-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I-H., Barret, T., Su, B., Deng, T., Karin, M., and Davis, R. A., JNK1: A protein kinase stimulated by UV light and HA-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037, 1994.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3    Barret, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.A.8
  • 35
    • 0028144846 scopus 로고
    • C-fos transcriptional activity stimulated by H protein kinase distinct from JNK and ERK
    • Deng, T., and Karim, M., c-fos transcriptional activity stimulated by H protein kinase distinct from JNK and ERK. Nature (London) 371, 171-175, 1994.
    • (1994) Nature (London) , vol.371 , pp. 171-175
    • Deng, T.1    Karim, M.2
  • 36
    • 0025720735 scopus 로고
    • Fos and the AP-1 complex in cell proliferation and transformation
    • Angel, P., and Karin, M., The role of Jun, Fos and the AP-1 complex in cell proliferation and transformation. Biochem. Biophys. Acta 1072, 129-157, 1991.
    • (1991) Biochem. Biophys. Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2    Jun, T.R.O.3
  • 37
    • 0026667860 scopus 로고
    • Transactivation by AP-1 is a molecular target of T cell clonal anergy
    • Kang, S. M., Beverley, B., Tran, A. G., Brorson, K., Schwartz, R., and Leonardo, M., Transactivation by AP-1 is a molecular target of T cell clonal anergy. Science 257, 1134-1138, 1992.
    • (1992) Science , vol.257 , pp. 1134-1138
    • Kang, S.M.1    Beverley, B.2    Tran, A.G.3    Brorson, K.4    Schwartz, R.5    Leonardo, M.6
  • 38
    • 0027214557 scopus 로고
    • Promoter specific trans-activation and inhibition mediated by Jun B
    • Hsu, J. C., Cressman, D. E., and Taub, R., Promoter specific trans-activation and inhibition mediated by Jun B. Cancer Res. 53, 3789-3794, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3789-3794
    • Hsu, J.C.1    Cressman, D.E.2    Taub, R.3
  • 39
    • 0025085508 scopus 로고
    • Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen
    • Newell, M. K., Haughn, L., Maroun, C. R., and Julius, M. H., Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen. Nature (London) 347, 286-289, 1990.
    • (1990) Nature (London) , vol.347 , pp. 286-289
    • Newell, M.K.1    Haughn, L.2    Maroun, C.R.3    Julius, M.H.4
  • 40
    • 0026784923 scopus 로고
    • T. H. Crosslinking of CD4 by human immunodeficiency virus gp!20 primes T cells for activation-induced apoptosis
    • Banda, N. K, Bernier, J., Kurahara, D. K., Kurrle, R., Haigwood, N., Sekaly, R. P., and Finkell, T. H.( Crosslinking of CD4 by human immunodeficiency virus gp!20 primes T cells for activation-induced apoptosis. J. Exp. Med. 176, 1099-1106, 1992.
    • (1992) J. Exp. Med. , vol.176 , pp. 1099-1106
    • Banda, N.K.1    Bernier, J.2    Kurahara, D.K.3    Kurrle, R.4    Haigwood, N.5    Sekaly, R.P.6
  • 41
    • 0026165453 scopus 로고
    • Functional consequences of CD4-TCR/CD3-interactions
    • Julius, M., Newell, K, Maroun, C., and Haughn, L., Functional consequences of CD4-TCR/CD3-interactions. Semin. Immunol. 3, 161-166, 1991.
    • (1991) Semin. Immunol. , vol.3 , pp. 161-166
    • Julius, M.1    Newell, K.2    Maroun, C.3    Haughn, L.4
  • 42
    • 0028147233 scopus 로고
    • Requirement for kinase activity of CD4-associated p561ck in antibody-triggered T cell signal transduction
    • Chu, K., and Littman, D. R., Requirement for kinase activity of CD4-associated p561ck in antibody-triggered T cell signal transduction. J. Biol. Chem. 269, 24095-24101, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24095-24101
    • Chu, K.1    Littman, D.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.