-
1
-
-
0025028960
-
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
-
Stem AS, Podlaski FJ, Hulmes JD, Pan YC, Quinn PM, Wolitzky AG, Familletti PC, Stremlo DL, Truitt T, Chizzonite R, and Gately, MK: Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc Natl Acad Sci USA 1990;87:6808-6812.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6808-6812
-
-
Stem, A.S.1
Podlaski, F.J.2
Hulmes, J.D.3
Pan, Y.C.4
Quinn, P.M.5
Wolitzky, A.G.6
Familletti, P.C.7
Stremlo, D.L.8
Truitt, T.9
Chizzonite, R.10
Gately, M.K.11
-
2
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chan S, Loudon R, Sherman F, Perussia B, and Trinchieri G: Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med 1989;170:827-845.
-
(1989)
J Exp Med
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
Loudon, R.7
Sherman, F.8
Perussia, B.9
Trinchieri, G.10
-
3
-
-
0026693587
-
Assignment of genes encoding a unique cytokine (IL-12) composed of two unrelated subunits to chromosomes 3 and 5
-
Sieburth D, Jabs EW, Warrington JA, Li X, Lasota J, LaForgia S, Kelleher K, Huebner K, Wasmuth JJ, and Wolf SF: Assignment of genes encoding a unique cytokine (IL-12) composed of two unrelated subunits to chromosomes 3 and 5. Genomics 1992;14:59-62.
-
(1992)
Genomics
, vol.14
, pp. 59-62
-
-
Sieburth, D.1
Jabs, E.W.2
Warrington, J.A.3
Li, X.4
Lasota, J.5
LaForgia, S.6
Kelleher, K.7
Huebner, K.8
Wasmuth, J.J.9
Wolf, S.F.10
-
4
-
-
0025783528
-
Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor
-
Gearing DP, and Cosman D: Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor [letter]. Cell 1991;66:9-10.
-
(1991)
Cell
, vol.66
, pp. 9-10
-
-
Gearing, D.P.1
Cosman, D.2
-
5
-
-
0026567028
-
Sequence similarity between NKSF and the IL-6/G-CSF family
-
Merberg DM, Wolf SF, and Clark SC: Sequence similarity between NKSF and the IL-6/G-CSF family [letter]. Immunol Today 1992;13:77-78.
-
(1992)
Immunol Today
, vol.13
, pp. 77-78
-
-
Merberg, D.M.1
Wolf, S.F.2
Clark, S.C.3
-
6
-
-
0026588207
-
Cloning and expression of murine IL-12
-
Schoenhaut DS, Chua AO, Wolitzky AG, Quinn PM, Dwyer CM, McComas W, Familletti PC, Gately MK, and Gubler U: Cloning and expression of murine IL-12. J Immunol 1992;148:3433-3440.
-
(1992)
J Immunol
, vol.148
, pp. 3433-3440
-
-
Schoenhaut, D.S.1
Chua, A.O.2
Wolitzky, A.G.3
Quinn, P.M.4
Dwyer, C.M.5
McComas, W.6
Familletti, P.C.7
Gately, M.K.8
Gubler, U.9
-
7
-
-
0026701132
-
Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells
-
D'Andrea A, Rengaraju M, Valiante NM, Chehimi J, Kubin M, Aste-Amezaga M, Chan SH, Kobayashi M, Young D, Nickbarg E, Chizzonite R, Wolf SF, Trinchieri and G: Production of natural killer cell stimulatory factor (NKSF/IL-12) by peripheral blood mononuclear cells. J Exp Med 1992;176:1387-1398.
-
(1992)
J Exp Med
, vol.176
, pp. 1387-1398
-
-
D'Andrea, A.1
Rengaraju, M.2
Valiante, N.M.3
Chehimi, J.4
Kubin, M.5
Aste-Amezaga, M.6
Chan, S.H.7
Kobayashi, M.8
Young, D.9
Nickbarg, E.10
Chizzonite, R.11
Wolf, S.F.12
Trinchieri, G.13
-
8
-
-
0028130251
-
Identification and induction of human keratinocyte-derived IL-12
-
Müller G, Saloga J, Germann T, Bellinghausen I, Mohamadzadeh M, Knop J, and Enk AH: Identification and induction of human keratinocyte-derived IL-12. J Clin Invest 1994;94:1799-1805.
-
(1994)
J Clin Invest
, vol.94
, pp. 1799-1805
-
-
Müller, G.1
Saloga, J.2
Germann, T.3
Bellinghausen, I.4
Mohamadzadeh, M.5
Knop, J.6
Enk, A.H.7
-
9
-
-
0028135018
-
IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines
-
Aragane Y, Riemann H, Bhardwaj RS, Schwarz A, Sawada Y, Yamada H, Luger TA, Kubin M, Trinchieri G, and Schwarz T: IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines. J Immunol 1994;153:5366-5372.
-
(1994)
J Immunol
, vol.153
, pp. 5366-5372
-
-
Aragane, Y.1
Riemann, H.2
Bhardwaj, R.S.3
Schwarz, A.4
Sawada, Y.5
Yamada, H.6
Luger, T.A.7
Kubin, M.8
Trinchieri, G.9
Schwarz, T.10
-
10
-
-
0030067458
-
IL-12 synthesis by human Langerhans cells
-
Kang KF, Kubin M, Cooper KD, Lessin SR, Trinchieri G, Rook AH: IL-12 synthesis by human Langerhans cells. J Immunol 1996;156:1402-1407.
-
(1996)
J Immunol
, vol.156
, pp. 1402-1407
-
-
Kang, K.F.1
Kubin, M.2
Cooper, K.D.3
Lessin, S.R.4
Trinchieri, G.5
Rook, A.H.6
-
11
-
-
0028906439
-
Interleukin-12 production by human polymorphonuclear leukocytes
-
Cassatella MA, Meda L, Gasperini S, D'Andrea A, Ma X, and Trinchieri G: Interleukin-12 production by human polymorphonuclear leukocytes. Eur J Immunol 1995;25:1-5.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1-5
-
-
Cassatella, M.A.1
Meda, L.2
Gasperini, S.3
D'Andrea, A.4
Ma, X.5
Trinchieri, G.6
-
12
-
-
0028967287
-
Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist
-
Gillessen S, Carvajal D, Ling P, Podlaski FJ, Stremlo DL, Familletti PC, Gubler U, Presky DH, Stem AS, and Gately MK: Mouse interleukin-12 (IL-12) p40 homodimer: A potent IL-12 antagonist. Eur J Immunol 1995;25:200-206.
-
(1995)
Eur J Immunol
, vol.25
, pp. 200-206
-
-
Gillessen, S.1
Carvajal, D.2
Ling, P.3
Podlaski, F.J.4
Stremlo, D.L.5
Familletti, P.C.6
Gubler, U.7
Presky, D.H.8
Stem, A.S.9
Gately, M.K.10
-
13
-
-
0027200981
-
The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer
-
Mattner F, Fischer S, Guckes S, Jin S, Kaulen H, Schmitt E, Rude E, and Germann T: The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer. Eur J Immunol 1993;23:2202-2208.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2202-2208
-
-
Mattner, F.1
Fischer, S.2
Guckes, S.3
Jin, S.4
Kaulen, H.5
Schmitt, E.6
Rude, E.7
Germann, T.8
-
14
-
-
0028819316
-
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity
-
Ling P, Gately MK, Gubler U, Stern AS, Lin P, Hollfelder K, Su C, Pan Y-CE, and Hakimi J: Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J Immunol 1995;154:116-127.
-
(1995)
J Immunol
, vol.154
, pp. 116-127
-
-
Ling, P.1
Gately, M.K.2
Gubler, U.3
Stern, A.S.4
Lin, P.5
Hollfelder, K.6
Su, C.7
Pan, Y.-C.E.8
Hakimi, J.9
-
15
-
-
43949163341
-
Interleukin-12 and its role in the generation of TH1 cells
-
Trinchieri G: Interleukin-12 and its role in the generation of TH1 cells. Immunol Today 1993;14:335-338.
-
(1993)
Immunol Today
, vol.14
, pp. 335-338
-
-
Trinchieri, G.1
-
16
-
-
0025819340
-
Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers
-
Chan SFI, Perussia B, Gupta JW, Kobayashi M, Pospisil M, Young HA, Wolf SF, Young D, Clark SC, and Trinchieri G: Induction of interferon gamma production by natural killer cell stimulatory factor: Characterization of the responder cells and synergy with other inducers. J Exp Med 1991;173:869-879.
-
(1991)
J Exp Med
, vol.173
, pp. 869-879
-
-
Chan, S.F.I.1
Perussia, B.2
Gupta, J.W.3
Kobayashi, M.4
Pospisil, M.5
Young, H.A.6
Wolf, S.F.7
Young, D.8
Clark, S.C.9
Trinchieri, G.10
-
17
-
-
0025873502
-
Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)
-
Gately MK, Desai BB, Wolitzky AG, Quinn PM, Dwyer CM, Podlaski FJ, Familletti PC, Sinigaglia F, Chizonnite R, Gubler U, and Stem, AS: Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J Immunol 1991;147:874-882.
-
(1991)
J Immunol
, vol.147
, pp. 874-882
-
-
Gately, M.K.1
Desai, B.B.2
Wolitzky, A.G.3
Quinn, P.M.4
Dwyer, C.M.5
Podlaski, F.J.6
Familletti, P.C.7
Sinigaglia, F.8
Chizonnite, R.9
Gubler, U.10
Stem, A.S.11
-
18
-
-
0026441372
-
Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells
-
Perussia B, Chan SH, D'Andrea A, Tsuji K, Santoli D, Pospisil M, Young D, Wolf SF, and Trinchieri G: Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells. J Immunol 1992;149:3495-3502.
-
(1992)
J Immunol
, vol.149
, pp. 3495-3502
-
-
Perussia, B.1
Chan, S.H.2
D'Andrea, A.3
Tsuji, K.4
Santoli, D.5
Pospisil, M.6
Young, D.7
Wolf, S.F.8
Trinchieri, G.9
-
19
-
-
0026520178
-
Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF
-
Robertson MJ, Soiffer RJ, Wolf SF, Manley TJ, Donahue C, Young D, Herrmann SH, and Ritz J: Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): Cytolytic activity and proliferation of NK cells are differentially regulated by NKSF. J Exp Med 1992;175:779-788.
-
(1992)
J Exp Med
, vol.175
, pp. 779-788
-
-
Robertson, M.J.1
Soiffer, R.J.2
Wolf, S.F.3
Manley, T.J.4
Donahue, C.5
Young, D.6
Herrmann, S.H.7
Ritz, J.8
-
20
-
-
0028096083
-
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo
-
Gately MK, Warrier RR, Honasoge S, Carvajal DM, Faherty DA, Connaughton SE, Anderson TD, Sarimento U, Hubbard BR, and Murphy M: Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo. Int Immunol 1994;6:157-167.
-
(1994)
Int Immunol
, vol.6
, pp. 157-167
-
-
Gately, M.K.1
Warrier, R.R.2
Honasoge, S.3
Carvajal, D.M.4
Faherty, D.A.5
Connaughton, S.E.6
Anderson, T.D.7
Sarimento, U.8
Hubbard, B.R.9
Murphy, M.10
-
21
-
-
0028908520
-
Antitumour effects of interleukin-12 (IL-12): Applications for the immunotherapy and gene therapy of cancer
-
Tahara H, and Lotze MT: Antitumour effects of interleukin-12 (IL-12): Applications for the immunotherapy and gene therapy of cancer. Gene Therapy 1995;2:96-106.
-
(1995)
Gene Therapy
, vol.2
, pp. 96-106
-
-
Tahara, H.1
Lotze, M.T.2
-
22
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR, Wright RB, Hubbard BR, Murphy M, Wolf SF, and Gately MK: Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 1993;178:1223-1230.
-
(1993)
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
Wright, R.B.4
Hubbard, B.R.5
Murphy, M.6
Wolf, S.F.7
Gately, M.K.8
-
23
-
-
0027953555
-
Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induced antitumor immunity to a murine melanoma in vivo
-
Tahara H, Zeh HJ, III, Storkus WJ, Pappo I, Watkins SC, Gubler U, Wolf SF, Robbins PD, and Lotze MT: Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induced antitumor immunity to a murine melanoma in vivo. Cancer Res 1994;54:182-19.
-
(1994)
Cancer Res
, vol.54
, pp. 182-219
-
-
Tahara, H.1
Zeh III, H.J.2
Storkus, W.J.3
Pappo, I.4
Watkins, S.C.5
Gubler, U.6
Wolf, S.F.7
Robbins, P.D.8
Lotze, M.T.9
-
24
-
-
0030068953
-
Characterization of anti-mouse IL-12 monoclonal antibodies and measurement of mouse IL-12 by ELISA
-
Wilkinson VL, Warrier RR, Truitt TP, Nunes P, Gately MK, and Presky DH: Characterization of anti-mouse IL-12 monoclonal antibodies and measurement of mouse IL-12 by ELISA. J Immunol Meth 1996;189:15-24.
-
(1996)
J Immunol Meth
, vol.189
, pp. 15-24
-
-
Wilkinson, V.L.1
Warrier, R.R.2
Truitt, T.P.3
Nunes, P.4
Gately, M.K.5
Presky, D.H.6
-
26
-
-
0029040855
-
Regulation of interleukin-12 expression in human monocytes: Selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes
-
Hayes MP, Wang J, and Norcross MA: Regulation of interleukin-12 expression in human monocytes: Selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. Blood 1995;86:646-650.
-
(1995)
Blood
, vol.86
, pp. 646-650
-
-
Hayes, M.P.1
Wang, J.2
Norcross, M.A.3
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