IL-12 synthesis by human Langerhans cells

Journal of Immunology

Volumn 156, Issue 4, 1996, Pages 1402-1407

  Kang, Kefei ^a,b   Kubin, Marek ^c   Cooper, Kevin D ^a,b,d   Lessin, Stuart R ^d,e   Trinchieri, Giorgio ^c   Rook, Alain H ^e  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c WISTAR INSTITUTE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12;

ARTICLE; CELLULAR DISTRIBUTION; DENDRITIC CELL; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LANGERHANS CELL; PRIORITY JOURNAL;

ADULT; BASE SEQUENCE; DNA PRIMERS; GENE EXPRESSION; HUMANS; INTERLEUKIN-12; LANGERHANS CELLS; MOLECULAR SEQUENCE DATA; RNA, MESSENGER;

EID: 0030067458     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Stingl, G., K. Tamaki, and S. I. Katz. 1980. Origin and function of epidermal Langerhans cells. Immunol. Rev 53:150.
2. Enk, A H , V. L. Angeloni, M C Udey, and S. I. Katz. 1993. An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin. J Immunol. 150:3698
3. Schreiber, S., O. Kilgus, E. Payer, R Kutil, A. Elbe, C. Mueller, and G. Stingl. 1992. Cytokine pattern of Langerhans cells isolated from murine epidermal cell cultures. J. Immunol. 149:3525.
4. Heufler, C., G Topar, F Koch, B. Trockenbacher, E. Kampgen, N. Romani, and G. Schuler. 1992. Cytokine gene expression in munne epidermal cell suspensions: interleukin 1 beta and macrophage inflammatory protein 1 alpha are selectively expressed in Langerhans cells but are differentially regulated in culture. J. Exp. Med. 176:1221.
5. Laub, R., S. Schreiber, and G. Stingl 1994. Functional significance of Langerhans cell derived IL-1 beta and IL-6 for the initiation of primary allogencic T-cell responses. J. Invest. Dermatol. 102:526.
6. Trinchieri, G 1993. Interleukin-12 and its role in the generation of TH1 cells. Immunol Today 14:335.
7. Kobayashi, M., L Fitz, M. Ryan, R M. Hewick, S. C. Clark, S. Chan, R. Loudon, F. Sherman, B. Perussia, and G, Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J. Exp. Med. 170.827.
8. Stern, A S., F. J. Podlaski, J. D. Hulmes, Y. C. Pan, P. M. Quinn, A. G. Wolitzky, P C Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, and et al 1990 Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells Proc. Natl. Acad. Sci. USA 87:6808.
9. D'Andrea, A., M. Rengaraju, N. M. Valiante, J. Chehimi, M. Kubin, M Aste, S. H. Chan, M Kobayashi, D. Young, E. Nickbarg, R. Chizzonite, S F Wolf, and G. Trinchieri. 1992. Production of natural killer cell stimulatory factor (Interlekin 12) by peripheral blood mononuclear cells. J. Exp. Med. 176:1387.
10. Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Pospisil, H. A, Young, S. F. Wolf, D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
11. Manetti, R , P. Parronchi, M. G. Giudizi, M.-P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper Type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J. Exp. Med. 177:1199.
12. + T cells through IL-12 produced by Listeria-induced macrophages Science 260:547.
13. Afonso, L. C. C., T. M. Scharton, L. Q. Vieira, M Wysocka, G. Trinchieri, and P. Scott. 1994. The adjuvant effect of interleukin-12 m a vaccine against Leishmania major. Science 263:235.
14. Meunier, L., J J Voorhees, and K. D Cooper. 1994. Retinoids modulate function, but not numbers, of antigen-presenting macrophages and keratinocytes in sunburned skin. J. Invest. Dermatol. 102:650.
15. + Langerhans cell-like interstitial dendritic antigen-presenting cells in murine dermis from dermal macrophages. J. Invest. Dermatol. 103.678.
16. Tamaki, K., H Fujiwara, and S. I. Katz. 1981. The role of epidermal cells m the induction and suppression of contact sensitivity. J. Invest. Dermatol. 76: 275.
17. + cells are capable of initiating delayed-type hypersensitivity responses. J. Invest. Dermatol 94: 267.
18. Cher, D J , and T. R. Mosmann. 1987. Two types of murine helper T cell clone. II Delayed-type hypersensitivity is mediated by Th1 clones. J Immunol. 138: 3688.
19. Roberts, L. K., G. J. Spangrude, R. A Daynes, and G G. Krueger. 1985. Correlation between keratinocyte expression of Ia and the intensity and duration of contact hypersensitivity responses in mice. J. Immunol. 135:2929.
20. Volc-Platzer, B., A. Steiner, T. H Radaszkiewicz, and K. Wolff. 1988. Recombinant gamma interferon and in vivo induction of HLA-DR antigens. Br. J. Dermatol. 119:155
21. + cells in human dermal cell suspensions: identification of a small subset responsible for potent dermal antigen-presenting cell activity with features analogous to Langerhans cells. J. Immunol. 151: 4067.
22. + macrophages that infiltrate human epidermis after in vivo ultraviolet exposure patently produce IL-10 and represent the major secretory source of epidermal IL-10 protein. J Immunol. 153:5256.
23. D'Andrea, A, M. Aste-Amezaga, N. M. Valiante, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
24. Inaba, K., G. Schuler, M. D. Witmer, J. Valinksy, B. Atassi, and R. M. Steinman. 1986. Immunologic properties of purified epidermal langerhans cells, distinct requirements for stimulation of unprimed and sensitized T lymphocytes J. Exp. Med. 164.605.
25. Klausner, R D , J. G. Donaldson, and J. Lippincott-Schwartz 1992. Brefeldin A, insights into the control of membrane traffic and organelle structure. J. Cell Biol 116:1071.
26. Aragane, Y., H. Riemann, R. S. Bhardwaj, A. Schwarz, Y. Sawada, H. Yamada, T. A. Luger, M. Kubin, G. Trinchieri, and T. Schwarz. 1994 IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines J Immunol 153:5366.
27. + T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. Int Immunol. 5:1119
28. Macatonia, S. E., N. A Hosken, M Litton, P. Vieira, C.-S. Hsieh, J. A. Culpepper, M. Wysocka, G. Trinchieri, K. M. Murphy, and A O'Garra. 1995. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J. of Immunol. 154:5071
29. Ohmen, J. D , J. M Hanifin, B. J. Nickoloff, T H. Rea, R Wyzykowski, J. Kim, D. Jullien, T. McHugh, A. S. Nassif, S. C Chan, and R. L. Modlin. 1995. Overexpression of IL-10 in atopic dermatitis: contrasting cytokine patterns with delayed-type hypersensitivity reactions. J. Immunol. 154:1956.
30. Hauser, C , C. M. Snapper, J. Ohara, W. E. Paul, and S. I. Katz. 1989. T helper cells grown with hapten-modified cultured Langerhans'cells produce interleukin 4 and stimulate IgE production by B cells. Eur. J. Immunol. 19:245.
31. Riemann, H., S Grabbe, A. Schwarz, Y. Aragane, T. A. Luger, M. Wysocka, M. Kubin, G. Trinchieri, and T. Schwarz. 1995. In vivo application of an interleukin 12 antibody induces hapten specific tolerance. J Invest. Dermatol. 104: 571.
32. Muller, G., J. Saloga, T Germann, I. Bellinghausen, M. Mohamadzadeh, J. Knop, and A. H Enk. 1994. Identification and induction of human keratinocyte-derived IL-12. J. Clin. Invest. 94:1799.
33. Bergstresser, P. R., G. B. Toews, and J. W. Streilein. 1980. Natural and perturbed distributions of Langerhans cells: responses to ultraviolet light, heterotopic skin grafting, and dinitrofluorobenzene sensitization. J Invest. Dermatol. 75:73.
34. Aberer, G., G. Schuler, G. Stingl, H. Honigsmann, and K. Wolff 1981. Ultraviolet light depletes surface markers of Langerhans cells. J. Invest. Dermatol. 76: 202.
35. Meunier, L., A. Gonzalez-Ramos, L. Oberhelman, C. Hammerberg, and K. D Cooper. 1992. UV-induced epidermal macrophages derive from a small dermal macrophage subset which undergoes marked expansion after UV injury. J Invest. Dermatol. 98.509.
36. + suppressor/cytatoxic lymphocytes J Immunol. 140:1738.
37. - CD11b (bright) monocytic/ macrophagic cells J. Immunol. 153:4915.
38. Chomarat, P., M.-C. Rissoan, J. Banchereau, and P. Miossec. 1993 Interferon gamma inhibits interleukin 10 production by monocytes. J. Exp Med. 177.523.
39. Romani, N., A Lenz, H. Glassei, and G Schuler. 1989. Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and function. J Invest. Dermatol 93:600
40. Streilein, J W., and S. F. Grammer. 1989. In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes. J. Immunol. 143:3925