Exclusion of expansion of 50 CAG/CTG trinucleotide repeats in bipolar disorder

American Journal of Psychiatry

Volumn 154, Issue 8, 1997, Pages 1146-1147

  Guy, Carol ^b   Bowen, Timothy ^b   Daniels, Johanna K ^b   Speight, Graham ^b   McKeon, Patrick ^b   Mynett Johnson, Lesley ^b   Claffey, Eileen ^b   McGuffin, Peter ^b   Owen, Michael J ^b   Craddock, Nick ^b   O'Donovan, Michael C ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

TRINUCLEOTIDE;

ALLELISM; ARTICLE; CLINICAL ARTICLE; DIAGNOSTIC APPROACH ROUTE; GENETIC SCREENING; HUMAN; HUMAN CELL; MANIC DEPRESSIVE PSYCHOSIS; NUCLEOTIDE REPEAT; PATHOGENESIS; PRIORITY JOURNAL; X CHROMOSOMAL INHERITANCE;

EID: 0030811514     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.154.8.1146     Document Type: Article

References (8)

1. O'Donovan MC, Owen MJ: Dynamic mutations and psychiatric genetics (editorial). Psychol Med 1996; 26:1-6
2. O'Donovan MC, Guy C, Craddock N, Murphy KC, Cardno AG, Jones LA, Owen MJ, McGuffin P: Expanded CAG repeats in schizophrenia and bipolar disorder. Nat Genet 1995; 10:380-381
3. Lindblad K, Nylander P-O, De Bruyn A, Sourey D, Zander C, Engstrom C, Holmgren G, Hudson T, Chotai J, Mendlewicz J, Van Broeckhoven C, Schalling M, Adolfsson R: Detection of expanded CAG repeats in bipolar affective disorder using the repeat expansion detection (RED) method. Neurobiology of Disease 1995; 2:55-62
4. O'Donovan MC, Guy C, Craddock N, Bowen T, McKeon P, Macedo A, Maier W, Wildenauer D, Aschauer HN, Sorbi S, Feldman E, Mynett-Johnson L, Claffey E, Nacmias B, Valente J, Dourado A, Grassi E, Lenzinger E, Heiden AM, Moorhead S, Harrison D, Williams J, McGuffin P, Owen MJ: Confirmation of association between expanded CAG/CTG repeats and both schizophrenia and bipolar disorder. Psychol Med 1996; 26: 1145-1153
5. Vincent JB, Klempan T, Parikh SS, Sasaki T, Meltzer HY, Sirugo G, Cola P, Petronis A, Kennedy JE: Frequency analysis of large CAG/CTG trinucleotide repeats in schizophrenia and bipolar affective disorder. Mol Psychiatry 1996; 1:141-148
6. Bowen T, Guy C, Speight G, Jones L, Cardno A, Murphy K, McGuffin P, Owen MJ, O'Donovan MC: Expansion of 50 CAG/ CTG repeats excluded in schizophrenia by application of a highly efficient approach using RED and a PCR screening set. Am J Hum Genet 1996; 59:912-917
7. Gastier JM, Brody T, Pulido JC, Businga T, Sunden S, Hu X, Maitra S, Buetow KH, Murray JC, Sheffield VC, Boguski M, Duyk GM, Hudson TJ: Development of a screening set for new (CAG/CTG)n dynamic mutations. Genomics 1996; 32:74-85
8. Jacobsen N, Daniels J, Moorhead S, Harrison D, Feldman E, McGuffin P, Owen MJ, Craddock N: Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23-q24.1. Psychiatr Genet 1996; 6:195-199