메뉴 건너뛰기




Volumn 8, Issue 1, 1996, Pages 72-77

Gene therapy strategies for novel cancer therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTISENSE OLIGONUCLEOTIDE; CARBOXYPEPTIDASE G2; COLONY STIMULATING FACTOR 1; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYTOCHROME P450 ISOENZYME; CYTOKINE; CYTOSINE DEAMINASE; GANCICLOVIR; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; PLASMID DNA; PROTEIN P53; PURINE NUCLEOSIDE PHOSPHORYLASE; RIBOZYME; SOMATOMEDIN C RECEPTOR; THYMIDINE KINASE; TOXIN; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0029945583     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001622-199601000-00013     Document Type: Review
Times cited : (20)

References (73)
  • 3
    • 0027988666 scopus 로고
    • Development of ribozymes for gene therapy
    • Sullivan SM: Development of ribozymes for gene therapy. J Invest Dermatol 1994, 103:85S-89S.
    • (1994) J Invest Dermatol , vol.103
    • Sullivan, S.M.1
  • 4
    • 0029294009 scopus 로고
    • Intracellular antibodies (intrabodies) as research reagents and therapeutic molecules for gene therapy
    • Marasco W: Intracellular antibodies (intrabodies) as research reagents and therapeutic molecules for gene therapy. Immunotechnology 1995, 1:1-19. This review provides a comprehensive update on the use of intracellular antibodies with the focus on gene therapy for HIV and cancer.
    • (1995) Immunotechnology , vol.1 , pp. 1-19
    • Marasco, W.1
  • 5
    • 0028037219 scopus 로고
    • Antisense oligonucleotides absorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice
    • Schwab G, Chavany C, Duroux I, Goubin G, Lebeau J, Helene C, Saison-Behmoaras T: Antisense oligonucleotides absorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice. Proc Natl Acad Sci U S A 1994, 91:10460-10464.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 10460-10464
    • Schwab, G.1    Chavany, C.2    Duroux, I.3    Goubin, G.4    Lebeau, J.5    Helene, C.6    Saison-Behmoaras, T.7
  • 6
    • 0028924955 scopus 로고
    • Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol
    • Wang S, Lee RJ, Cauchon G, Gorenstein DG, Low PS: Delivery of antisense oligodeoxyribonucleotides against the human epidermal growth factor receptor into cultured KB cells with liposomes conjugated to folate via polyethylene glycol. Proc Natl Acad Sci U S A 1995, 92:3318-3322.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3318-3322
    • Wang, S.1    Lee, R.J.2    Cauchon, G.3    Gorenstein, D.G.4    Low, P.S.5
  • 7
    • 0028102004 scopus 로고
    • Inhibition of tumor growth in liver epithelial cells transfected with a transforming growth factor α antisense gene
    • Laird AD, Brown PI, Fausto N: Inhibition of tumor growth in liver epithelial cells transfected with a transforming growth factor α antisense gene. Cancer Res 1994, 54: 4224-4232.
    • (1994) Cancer Res , vol.54 , pp. 4224-4232
    • Laird, A.D.1    Brown, P.I.2    Fausto, N.3
  • 8
    • 0028904465 scopus 로고
    • Inhibition of proliferation by L-myc antisense DNA for the translational initiation site in human small cell lung cancer
    • Dosaka-Akita H, Akie K, Hiroumi H, Kinoshita I, Kawakami Y, Murakami A: Inhibition of proliferation by L-myc antisense DNA for the translational initiation site in human small cell lung cancer. Cancer Res 1995, 55:1559-1564.
    • (1995) Cancer Res , vol.55 , pp. 1559-1564
    • Dosaka-Akita, H.1    Akie, K.2    Hiroumi, H.3    Kinoshita, I.4    Kawakami, Y.5    Murakami, A.6
  • 9
    • 0028659793 scopus 로고
    • Episomal expression of sense and antisense insulin-like growth factor (IGF)-blnding protein-4 complementary DNA alters the mltogenlc response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-1
    • Singh P, Dai B, Dhruva B, Widen SG: Episomal expression of sense and antisense insulin-like growth factor (IGF)-blnding protein-4 complementary DNA alters the mltogenlc response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-1. Cancer Res 1994, 54:6563-6570.
    • (1994) Cancer Res , vol.54 , pp. 6563-6570
    • Singh, P.1    Dai, B.2    Dhruva, B.3    Widen, S.G.4
  • 10
    • 0028086553 scopus 로고
    • Antisense-mediated reduction in insulin-like growth factor-1 receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma
    • Shapiro DN, Jones BG, Shapiro LH, Dias P, Houghton PJ: Antisense-mediated reduction in insulin-like growth factor-1 receptor expression suppresses the malignant phenotype of a human alveolar rhabdomyosarcoma. J Clin Invest 1994, 94:1235-1242.
    • (1994) J Clin Invest , vol.94 , pp. 1235-1242
    • Shapiro, D.N.1    Jones, B.G.2    Shapiro, L.H.3    Dias, P.4    Houghton, P.J.5
  • 11
    • 0028050256 scopus 로고
    • Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor
    • Resnicoff M, Coppola D, Sell C, Rubin R, Ferrone S, Baserga R: Growth inhibition of human melanoma cells in nude mice by antisense strategies to the type 1 insulin-like growth factor receptor. Cancer Res 1994, 54:4848-4850.
    • (1994) Cancer Res , vol.54 , pp. 4848-4850
    • Resnicoff, M.1    Coppola, D.2    Sell, C.3    Rubin, R.4    Ferrone, S.5    Baserga, R.6
  • 12
    • 0028920352 scopus 로고
    • Loss of the metastatic phenotype in murine carcinoma cells expressing an antisense RNA to the insulin-like growth factor receptor
    • Long L, Rubin R, Baserga R, Brodt P: Loss of the metastatic phenotype in murine carcinoma cells expressing an antisense RNA to the insulin-like growth factor receptor. Cancer Res 1995, 55:1006-1009.
    • (1995) Cancer Res , vol.55 , pp. 1006-1009
    • Long, L.1    Rubin, R.2    Baserga, R.3    Brodt, P.4
  • 13
    • 0028340397 scopus 로고
    • Specific reduction in osteopontin synthesis by antisense RNA inhibits the tumorigenicity of transformed Rat1 fibroblasts
    • Gardner HAR, Berse B, Senger DR: Specific reduction in osteopontin synthesis by antisense RNA inhibits the tumorigenicity of transformed Rat1 fibroblasts. Oncogene 1994, 9:2321-2326.
    • (1994) Oncogene , vol.9 , pp. 2321-2326
    • Gardner, H.A.R.1    Berse, B.2    Senger, D.R.3
  • 14
    • 0029050664 scopus 로고
    • A single-injection protein kinase A-directed antisense treatment to inhibit tumor growth
    • Nesterova M, Cho-Chung YS: A single-injection protein kinase A-directed antisense treatment to inhibit tumor growth. Nat Med 1995, 1:528-533.
    • (1995) Nat Med , vol.1 , pp. 528-533
    • Nesterova, M.1    Cho-Chung, Y.S.2
  • 15
    • 0028700483 scopus 로고
    • Ribozyme-mediated in vitro cleavage of transcripts arising from the major transforming genes of human Papillomavirus type 16
    • Lu D, Chatterjee S, Brar D, Wong KK Jr: Ribozyme-mediated in vitro cleavage of transcripts arising from the major transforming genes of human Papillomavirus type 16. Cancer Gene Ther 1994, 1:267-277.
    • (1994) Cancer Gene Ther , vol.1 , pp. 267-277
    • Lu, D.1    Chatterjee, S.2    Brar, D.3    Wong Jr., K.K.4
  • 16
    • 0028939524 scopus 로고
    • Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias
    • Leopold LH, Shore SK, Newkirk TA, Reddy RMV, Reddy EP: Multi-unit ribozyme-mediated cleavage of bcr-abl mRNA in myeloid leukemias. Blood 1995, 85:2162-2170.
    • (1995) Blood , vol.85 , pp. 2162-2170
    • Leopold, L.H.1    Shore, S.K.2    Newkirk, T.A.3    Reddy, R.M.V.4    Reddy, E.P.5
  • 17
    • 0029069106 scopus 로고
    • Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme
    • Feng M, Cabrera G, Deshane J, Scanlon KJ, Curiel DT: Neoplastic reversion accomplished by high efficiency adenoviral-mediated delivery of an anti-ras ribozyme. Cancer Res 1995, 55:2024-2028. Use of a recombinant adenoviral vector to efficiently deliver a H-RAS ribozyme was reported to revert the neoplastic phenotype in mutant H-RAS-expressing cells.
    • (1995) Cancer Res , vol.55 , pp. 2024-2028
    • Feng, M.1    Cabrera, G.2    Deshane, J.3    Scanlon, K.J.4    Curiel, D.T.5
  • 18
    • 0028471332 scopus 로고
    • Dominant negative mutants: Tools for the study of protein function in vitro and in vivo
    • Sheppard D: Dominant negative mutants: tools for the study of protein function in vitro and in vivo. Am J Respir Cell Mol Biol 1994, 11:1-6. This review covers recent strategies for studying protein function based on dominant negative mutants. It provides a comprehensive overview and includes a variety of clinically relevant examples.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 1-6
    • Sheppard, D.1
  • 19
    • 0028833699 scopus 로고
    • Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF
    • Claffey KP, Senger DR, Spiegelman BM: Structural requirements for dimerization, glycosylation, secretion, and biological function of VPF/VEGF. Biochim Biophys Acta 1995, 1246:1-9.
    • (1995) Biochim Biophys Acta , vol.1246 , pp. 1-9
    • Claffey, K.P.1    Senger, D.R.2    Spiegelman, B.M.3
  • 20
    • 0028533575 scopus 로고
    • Suppression of various human tumor cell lines by a dominant negative H-ras mutant
    • Ogiso Y, Sakai N, Watari H, Yokoyama T, Kuzumaki N: Suppression of various human tumor cell lines by a dominant negative H-ras mutant. Gene Ther 1994, 1:403-407.
    • (1994) Gene Ther , vol.1 , pp. 403-407
    • Ogiso, Y.1    Sakai, N.2    Watari, H.3    Yokoyama, T.4    Kuzumaki, N.5
  • 21
    • 0028500163 scopus 로고
    • Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines
    • Deshane J, Loechel F, Conry RM, Siegal GP, King CR, Curiel DT: Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines. Gene Ther 1994, 1:332-337. An intracellular single-chain antibody, targeted to the endoplasmic reticulum was directed against the erbB-2 oncogene.
    • (1994) Gene Ther , vol.1 , pp. 332-337
    • Deshane, J.1    Loechel, F.2    Conry, R.M.3    Siegal, G.P.4    King, C.R.5    Curiel, D.T.6
  • 22
    • 0028148050 scopus 로고
    • Intracellular expression of single chain antibodies reverts erbB-2 transformation
    • Beerli RR, Weis W, Hynes NE: Intracellular expression of single chain antibodies reverts erbB-2 transformation. J Biol Chem 1994, 269:23931-23936.
    • (1994) J Biol Chem , vol.269 , pp. 23931-23936
    • Beerli, R.R.1    Weis, W.2    Hynes, N.E.3
  • 23
    • 0028030096 scopus 로고
    • Autocrine inhibition of the epidermal growth factor receptor by intracellular expression of a single-chain antibody
    • Beerli RR, Wels W, Hynes NE: Autocrine inhibition of the epidermal growth factor receptor by intracellular expression of a single-chain antibody. Biochem Biophys Res Commun 1994, 2:666-672.
    • (1994) Biochem Biophys Res Commun , vol.2 , pp. 666-672
    • Beerli, R.R.1    Wels, W.2    Hynes, N.E.3
  • 24
    • 0029033815 scopus 로고
    • Development and characterization of three recombinant single chain antibody fragments (scFvs) directed against the CD19 antigen
    • Bejcek BE, Wang D, Berven E, Pennell CA, Peiper SC, Poppema S, Uckun FM, Kersey JH: Development and characterization of three recombinant single chain antibody fragments (scFvs) directed against the CD19 antigen. Cancer Res 1995, 55:2346-2351.
    • (1995) Cancer Res , vol.55 , pp. 2346-2351
    • Bejcek, B.E.1    Wang, D.2    Berven, E.3    Pennell, C.A.4    Peiper, S.C.5    Poppema, S.6    Uckun, F.M.7    Kersey, J.H.8
  • 25
    • 0028955535 scopus 로고
    • Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the a subunit of the receptor
    • Richardson JH, Sodroski JG, Waldman TA, Marasco WA: Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the a subunit of the receptor. Proc Natl Acad Sci U S A 1995, 92:3137-3141.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 3137-3141
    • Richardson, J.H.1    Sodroski, J.G.2    Waldman, T.A.3    Marasco, W.A.4
  • 27
    • 0028143201 scopus 로고
    • Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model
    • Fujiwara T, Cai DW, Georges RN, Mukhopadhyay T, Grimm EA, Roth JA: Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model. J Natl Cancer Inst 1994, 86:1458-1462. This paper demonstrates that direct administration of a retroviral vector-expressing wild-type p53 may inhibit local growth of human lung cancer cells that are deficient in wild-type p53.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1458-1462
    • Fujiwara, T.1    Cai, D.W.2    Georges, R.N.3    Mukhopadhyay, T.4    Grimm, E.A.5    Roth, J.A.6
  • 30
    • 0028897315 scopus 로고
    • Tumor suppressive role of an androgen-regulated epithelial cell adhesion molecule (E-CAM) in prostate carcinoma cell revealed by sense and antisense approaches
    • Hsieh J-T, Luo W, Song W, Wang Y, Kleinerman DI, Van NT, Lin S-H: Tumor suppressive role of an androgen-regulated epithelial cell adhesion molecule (E-CAM) in prostate carcinoma cell revealed by sense and antisense approaches. Cancer Res 1995, 55:190-197.
    • (1995) Cancer Res , vol.55 , pp. 190-197
    • Hsieh, J.-T.1    Luo, W.2    Song, W.3    Wang, Y.4    Kleinerman, D.I.5    Van, N.T.6    Lin, S.-H.7
  • 35
    • 0028919172 scopus 로고
    • Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice
    • Mueller BM, YU YB, Laug WE: Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice. Proc Natl Acad Sci U S A 1995, 92:205-209.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 205-209
    • Mueller, B.M.1    Yb, Y.U.2    Laug, W.E.3
  • 36
    • 0028908860 scopus 로고
    • Cytotoxic activity of chimeric toxins containing the epidermal growth factor-like domain of heregulins fused to PE38KDEL, a truncated recombinant form of Pseudomonas exotoxin
    • Kihara A, Pastan I: Cytotoxic activity of chimeric toxins containing the epidermal growth factor-like domain of heregulins fused to PE38KDEL, a truncated recombinant form of Pseudomonas exotoxin. Cancer Res 1995, 55:71-77.
    • (1995) Cancer Res , vol.55 , pp. 71-77
    • Kihara, A.1    Pastan, I.2
  • 37
    • 0027935422 scopus 로고
    • Epidermal growth factor receptors in human breast carcinoma cells: A potential selective target for transforming growth factor α-Pseudomonas exotoxin 40 fusion protein
    • Arteaga CL, Hurd SD, Dugger TC, Winnier AR, Robertson JB: Epidermal growth factor receptors in human breast carcinoma cells: a potential selective target for transforming growth factor α-Pseudomonas exotoxin 40 fusion protein. Cancer Res 1994, 54:4703-4709.
    • (1994) Cancer Res , vol.54 , pp. 4703-4709
    • Arteaga, C.L.1    Hurd, S.D.2    Dugger, T.C.3    Winnier, A.R.4    Robertson, J.B.5
  • 38
    • 0028702018 scopus 로고
    • Drug sensitivity ("suicide") genes for selective cancer chemotherapy
    • Moolten FL: Drug sensitivity ("suicide") genes for selective cancer chemotherapy. Cancer Gene Ther 1994, 1:279-287.
    • (1994) Cancer Gene Ther , vol.1 , pp. 279-287
    • Moolten, F.L.1
  • 40
    • 0025291567 scopus 로고
    • Mosaicism induced by gene insertion as a means of improving chemotherapeutic selectivity
    • Moolten FL: Mosaicism induced by gene insertion as a means of improving chemotherapeutic selectivity. Crit Rev Immunol 1990, 10:203-233.
    • (1990) Crit Rev Immunol , vol.10 , pp. 203-233
    • Moolten, F.L.1
  • 41
    • 0026599586 scopus 로고
    • Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5 fluorocytosine: A negative selection system
    • Mullen CA, Kilstrup M, Blaese RM: Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5 fluorocytosine: a negative selection system. Proc Natl Acad Sci U S A 1992, 89:33-37.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 33-37
    • Mullen, C.A.1    Kilstrup, M.2    Blaese, R.M.3
  • 42
    • 0028989592 scopus 로고
    • 5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory
    • Consalvo M, Mullen CA, Modesti A, Musiani P, Allione A, Cavallo F, Giovarelli M, Forni G: 5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory. J Immunol 1995, 154:5302-5312.
    • (1995) J Immunol , vol.154 , pp. 5302-5312
    • Consalvo, M.1    Mullen, C.A.2    Modesti, A.3    Musiani, P.4    Allione, A.5    Cavallo, F.6    Giovarelli, M.7    Forni, G.8
  • 43
    • 0028465423 scopus 로고
    • Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines
    • Sorscher EJ, Peng S, Bebok Z, Allan PW, Bennett LL Jr, Parker WB: Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines. Gene Ther 1994, 1:233-238. The bacterial DEOD gene was used to catalyze the conversion of a normally nontoxic adenine analogue. A bystander killing effect was reported in colon carcinoma cells expressing DeoD and treated with the 6-methylpurine substrate.
    • (1994) Gene Ther , vol.1 , pp. 233-238
    • Sorscher, E.J.1    Peng, S.2    Bebok, Z.3    Allan, P.W.4    Bennett Jr., L.L.5    Parker, W.B.6
  • 44
    • 0027942213 scopus 로고
    • Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p185
    • Eccles SA, Court WJ, Box GA, Dean CJ, Melton RG, Springer CJ: Regression of established breast carcinoma xenografts with antibody-directed enzyme prodrug therapy against c-erbB2 p185. Cancer Res 1994, 54:5171-5177. The bacterial carboxypeptidase G2 enzyme was targeted to malignant breast cells overexpressing erbB-2 via a rat monoclonal antibody against the external domain of the human erbB-2 receptor. The authors used a mustard alkylating agent as a prodrug, and a dose-dependent tumor stasis or regression was reported.
    • (1994) Cancer Res , vol.54 , pp. 5171-5177
    • Eccles, S.A.1    Court, W.J.2    Box, G.A.3    Dean, C.J.4    Melton, R.G.5    Springer, C.J.6
  • 45
    • 0029161615 scopus 로고
    • The "bystander effect": Association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice
    • Colombo BM, Benedetti S, Ottolenghi S, Mora M, Polio B, Poli G, Finocchiaro G: The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice. Hum Gene Ther 1995, 6:763-772.
    • (1995) Hum Gene Ther , vol.6 , pp. 763-772
    • Colombo, B.M.1    Benedetti, S.2    Ottolenghi, S.3    Mora, M.4    Polio, B.5    Poli, G.6    Finocchiaro, G.7
  • 47
    • 0028016249 scopus 로고
    • Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1
    • Jia WW-G, McDermott M, Goldie J, Cynader M, Tan J, Tufaro F: Selective destruction of gliomas in immunocompetent rats by thymidine kinase-defective herpes simplex virus type 1. J Natl Cancer Inst 1994, 86:1209-1215.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1209-1215
    • Jia, W.W.-G.1    McDermott, M.2    Goldie, J.3    Cynader, M.4    Tan, J.5    Tufaro, F.6
  • 48
    • 0028071271 scopus 로고
    • The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats
    • Ram Z, Walbridge S, Shawker T, Culver KW, Blaese RM, Oldfield EH: The effect of thymidine kinase transduction and ganciclovir therapy on tumor vasculature and growth of 9L gliomas in rats. J Neurosurg 1994, 81:256-260.
    • (1994) J Neurosurg , vol.81 , pp. 256-260
    • Ram, Z.1    Walbridge, S.2    Shawker, T.3    Culver, K.W.4    Blaese, R.M.5    Oldfield, E.H.6
  • 49
    • 0028075655 scopus 로고
    • Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component
    • Vile RG, Nelson JA, Castleden S, Chong H, Hart IR: Systemic gene therapy of murine melanoma using tissue specific expression of the HSVtk gene involves an immune component. Cancer Res 1994, 54:6228-6234. This paper provides evidence that an immune component may play a role in the bystander effect seen in murine melanoma cells expressing the HSVTK gene from the tyrosinase promoter in a retroviral construct.
    • (1994) Cancer Res , vol.54 , pp. 6228-6234
    • Vile, R.G.1    Nelson, J.A.2    Castleden, S.3    Chong, H.4    Hart, I.R.5
  • 50
    • 0028116059 scopus 로고
    • Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene
    • Osaki T, Tanio Y, Tachibana I, Hosoe S, Kumagai T, Kawase I, Oikawa S, Kishimoto T: Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene. Cancer Res 1994, 54:5258-5261.
    • (1994) Cancer Res , vol.54 , pp. 5258-5261
    • Osaki, T.1    Tanio, Y.2    Tachibana, I.3    Hosoe, S.4    Kumagai, T.5    Kawase, I.6    Oikawa, S.7    Kishimoto, T.8
  • 52
    • 0028127077 scopus 로고
    • Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir
    • Manome Y, Abe M, Hagen MF, Fine HA, Kufe DW: Enhancer sequences of the DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir. Cancer Res 1994, 54:5408-5413. Enhanced sensitivity of breast cancer cells to ganciclovir was achieved via transcriptional regulation of HSVTK expression with an enhancer sequence from the breast specific DF3 promoter. Evidence for a bystander effect was also shown.
    • (1994) Cancer Res , vol.54 , pp. 5408-5413
    • Manome, Y.1    Abe, M.2    Hagen, M.F.3    Fine, H.A.4    Kufe, D.W.5
  • 55
    • 0028907668 scopus 로고
    • Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model
    • O'Malley BW Jr, Chen S-H, Schwartz MR, Woo SLC: Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model. Cancer Res 1995, 55:1080-1085.
    • (1995) Cancer Res , vol.55 , pp. 1080-1085
    • O'Malley Jr., B.W.1    Chen, S.-H.2    Schwartz, M.R.3    Woo, S.L.C.4
  • 56
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector producer cells for treatment of experimental brain tumors
    • Culver KW, Ram Z, Walbridge S, Ishii H, Oldfield EH, Blaese RM: In vivo gene transfer with retroviral vector producer cells for treatment of experimental brain tumors. Science 1992, 256:1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Walbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 57
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy
    • Bi LW, Parysek LM, Warnick R, Stambrook PJ: In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy. Hum Gene Ther 1993, 4:725-731.
    • (1993) Hum Gene Ther , vol.4 , pp. 725-731
    • Bi, L.W.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 58
    • 9444241799 scopus 로고
    • The Gene Therapy of Cancer
    • Edited by VT DeVita Jr, S Hellman, SA Rosenberg. Philadelphia: JB Lipincott
    • Hwu P: The Gene Therapy of Cancer. In Principles and Practice of Oncology. Edited by VT DeVita Jr, S Hellman, SA Rosenberg. Philadelphia: JB Lipincott; 1995: 1-13.
    • (1995) Principles and Practice of Oncology , pp. 1-13
    • Hwu, P.1
  • 59
    • 0028911381 scopus 로고
    • Cytokine gene-modified vaccines for immunotherapy of cancer
    • Bubenik J: Cytokine gene-modified vaccines for immunotherapy of cancer [review]. Int J Oncol 1995, 6:45-49.
    • (1995) Int J Oncol , vol.6 , pp. 45-49
    • Bubenik, J.1
  • 60
    • 0028940375 scopus 로고
    • In vivo cytokine gene transfer by gene gun reduces tumor growth in mice
    • Sun WH, Burkholder JK, Sun J, Culp J, Turner J, Lu XG, Pugh TD, Ershler WB, Yang N-S: In vivo cytokine gene transfer by gene gun reduces tumor growth in mice. Proc Natl Acad Sci U S A 1995, 92:2889-2893. This paper describes an in vivo cancer gene therapy approach to introduce cytokine genes into tumor-bearing animals by Accell (Agracetus) particle-mediated gene transfer. This "gene gun" was reported to achieve up to 100-fold higher transgene expression.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2889-2893
    • Sun, W.H.1    Burkholder, J.K.2    Sun, J.3    Culp, J.4    Turner, J.5    Lu, X.G.6    Pugh, T.D.7    Ershler, W.B.8    Yang, N.-S.9
  • 61
    • 0027964373 scopus 로고
    • In vitro modulation of the invasive and metastatic potentials of human renal cell carcinoma by interteukin-2 and/or interferon-alpha gene transfer
    • Hathorn RW, Tso C-L, Kaboo R, Pang S, Figlin R, Sawyers C, deKernion JB, Belldegrun A: In vitro modulation of the invasive and metastatic potentials of human renal cell carcinoma by interteukin-2 and/or interferon-alpha gene transfer. Cancer 1994, 74:1904-1911.
    • (1994) Cancer , vol.74 , pp. 1904-1911
    • Hathorn, R.W.1    Tso, C.-L.2    Kaboo, R.3    Pang, S.4    Figlin, R.5    Sawyers, C.6    DeKernion, J.B.7    Belldegrun, A.8
  • 62
    • 0028504791 scopus 로고
    • Suppression of in vivo tumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-α cDNA
    • Han SK, Brody SL, Crystal RG: Suppression of in vivo tumorigenicity of human lung cancer cells by retrovirus-mediated transfer of the human tumor necrosis factor-α cDNA. Am J Respir Cell Mol Biol 1994, 11:270-278.
    • (1994) Am J Respir Cell Mol Biol , vol.11 , pp. 270-278
    • Han, S.K.1    Brody, S.L.2    Crystal, R.G.3
  • 64
    • 0028978033 scopus 로고
    • Cytokine gene therapy with interleukin-2-transduced fibroblasts: Effects of IL-2 dose on anti-tumor immunity
    • Fakhrai H, Shawler DL, Gjerset R, Naviaux RK, Koziol J, Royston I, Sobol RE: Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity. Hum Gene Ther 1995, 6:591-601.
    • (1995) Hum Gene Ther , vol.6 , pp. 591-601
    • Fakhrai, H.1    Shawler, D.L.2    Gjerset, R.3    Naviaux, R.K.4    Koziol, J.5    Royston, I.6    Sobol, R.E.7
  • 66
    • 0029037056 scopus 로고
    • Macrophage colony-stimulating factor complementary DNA: A candidate for gene therapy in metastatic melanoma
    • Walsh P, Dorner A, Duke RC, Su L-J, Glode LM: Macrophage colony-stimulating factor complementary DNA: a candidate for gene therapy in metastatic melanoma. J Natl Cancer Inst 1995, 87:809-816. This paper reports that genetic induction of murine melanoma cells to express macrophage colony-stimulating factor elicited an efficient antitumor response in vivo and prolonged survival.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 809-816
    • Walsh, P.1    Dorner, A.2    Duke, R.C.3    Su, L.-J.4    Glode, L.M.5
  • 67
    • 0027992479 scopus 로고
    • In vivo delivery of interleukin-4 by a recombinant vaccinia virus prevents tumor development in mice
    • Elkins KL, Ennist DL, Winegar RK, Weir JP: In vivo delivery of interleukin-4 by a recombinant vaccinia virus prevents tumor development in mice. Hum Gene Ther 1994, 5:809-820.
    • (1994) Hum Gene Ther , vol.5 , pp. 809-820
    • Elkins, K.L.1    Ennist, D.L.2    Winegar, R.K.3    Weir, J.P.4
  • 68
    • 0028991827 scopus 로고
    • Enhancement of Interleukin-4 mediated tumor regression in athymic mice by in situ retroviral gene transfer
    • Wei MX, Tamiya T, Hurford RK Jr, Boviatsis EJ, Tepper RI, Chiocca EA: Enhancement of Interleukin-4 mediated tumor regression in athymic mice by in situ retroviral gene transfer. Hum Gene Ther 1995, 6:437-443.
    • (1995) Hum Gene Ther , vol.6 , pp. 437-443
    • Wei, M.X.1    Tamiya, T.2    Hurford Jr., R.K.3    Boviatsis, E.J.4    Tepper, R.I.5    Chiocca, E.A.6
  • 70
    • 0028036728 scopus 로고
    • Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules
    • Hodge JW, Abrams S, Schlom J, Kantor JA: Induction of antitumor immunity by recombinant vaccinia viruses expressing B7-1 or B7-2 costimulatory molecules. Cancer Res 1994, 54:5552-5555.
    • (1994) Cancer Res , vol.54 , pp. 5552-5555
    • Hodge, J.W.1    Abrams, S.2    Schlom, J.3    Kantor, J.A.4
  • 71
    • 0028646191 scopus 로고
    • Specificity and longevity of antitumor immune responses induced by B7-transfected tumors
    • Townsend SE, Su FW, Atherton JM, Allison JP: Specificity and longevity of antitumor immune responses induced by B7-transfected tumors. Cancer Res 1994, 54:6477-6483.
    • (1994) Cancer Res , vol.54 , pp. 6477-6483
    • Townsend, S.E.1    Su, F.W.2    Atherton, J.M.3    Allison, J.P.4
  • 72
    • 0028853124 scopus 로고
    • A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity
    • Conry RM, LoBuglio AF, Loechel F, Moore SE, Sumerel LA, Barlow DL, Curiel DT: A carcinoembryonic antigen polynucleotide vaccine has in vivo antitumor activity. Gene Ther 1995, 2:59-65. A plasmid encoding the cDNA for CEA functioned as a polynucleotide vaccine to elicit humor and cellular immune responses and protected against syngenic CEA-expressing colon cancer cells.
    • (1995) Gene Ther , vol.2 , pp. 59-65
    • Conry, R.M.1    Lobuglio, A.F.2    Loechel, F.3    Moore, S.E.4    Sumerel, L.A.5    Barlow, D.L.6    Curiel, D.T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.