Preliminary risk-benefit analysis of ropivacaine in labour and following surgery

Drug Safety

Volumn 16, Issue 6, 1997, Pages 391-402

  Cederholm, Ingemar ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; OPIATE; ROPIVACAINE;

ABDOMINAL SURGERY; ANALGESIA; BACKACHE; BRADYCARDIA; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM DISEASE; CESAREAN SECTION; CHOLECYSTECTOMY; CLINICAL TRIAL; DRUG PROTEIN BINDING; EPIDURAL DRUG ADMINISTRATION; FEVER; HERNIOPLASTY; HUMAN; HYPOTENSION; INSTRUMENTAL DELIVERY; INTRAVENOUS DRUG ADMINISTRATION; LABOR; LIPID SOLUBILITY; MOTOR NERVE BLOCK; NAUSEA; NERVE BLOCK; NONHUMAN; ORTHOPEDIC SURGERY; PAIN; PARESTHESIA; PKA; POSTOPERATIVE ANALGESIA; PREGNANCY; PRIORITY JOURNAL; REVIEW; RISK BENEFIT ANALYSIS; SENSORY NERVE; SHEEP; SUBCUTANEOUS DRUG ADMINISTRATION; URINE RETENTION;

EID: 0030803357     PISSN: 01145916     EISSN: None     Source Type: Journal    
DOI: 10.2165/00002018-199716060-00005     Document Type: Review

References (60)

1. af Ekenstam B, Egnér B, Pettersson G. Local anaesthetics I. N-alkyl pyrrolidine and N-alkyl piperidine carboxylic acid amides. Acta Chem Scand 1957; 11: 1183-90
2. Edde RR, Deutsch S. Cardiac arrest after interscalene brachial-plexus block. Anesth Analg 1977; 56: 446-7
3. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979; 51: 285-7
4. Covino BG. Clinical pharmacology of local anesthetic agents. In: Cousins MJ, Bridenbaugh PO, editors. Neural blockade in clinical anesthesia and management of pain. 2nd ed. Philadelphia: J B Lippincott Company, 1988: 111-44
5. Aps C, Reynolds F. An intradermal study of the local anaesthetic and vascular effects of the isomers of bupivacaine. Br J Clin Pharmacol 1978; 6: 63-8
6. Pryor M, Huang YF, Mather L. Comparison of the cardiac effects of S- and RS-bupivacaine in awake sheep [abstract]. 11th World Congress of Anaesthesiologists; 1996 Apr 14-20; Sydney, D457
7. Mather LE, Huang YF, Veering BT, et al. Comparative toxicity of bupivacaine and levobupivacaine in sheep: clinical implications [abstract]. 11th World Congress of Anaesthesiologists; 1996 Apr 14-20; Sydney, F135
8. International data sheet. Naropin® (ropivacaine HCl) product monograph. Oxford: Oxford Clinical Communications, 1996: 42-52
9. Oda Y, Furuichi K, Tanaka K, et al. Metabolism of a new local anesthetic, ropivacaine, by human hepatic cytochrome P450. Anesthesiology 1995; 82: 214-20
10. Lee A, Fagan D, Lamont M, et al. Disposition kinetics of ropivacaine in humans. Anesth Analg 1989; 69: 736-8
11. Rosenberg PH, Heinonen E. Differential sensitivity of A and C nerve fibres to long-acting amide local anaesthetics. Br J Anaesth 1983; 55: 163-7
12. Rosenberg PH, Kyttä J, Alila A. Absorption of bupivacaine, etidocaine, lignocaine and ropivacaine into N-heptane, rat sciatic nerve, and human extradural and subcutaneous fat. Br J Anaesth 1986; 58: 310-4
13. Forsberg T, Westman I, Akerman B. Differences in vasoactivity between ropivacaine and bupivacaine [abstract]. Reg Anesth 1988; 11: P12
14. Akerman B, Hellberg I-B, Trossvik C. Primary evaluation of the local anaesthetic properties of the amino amide agent ropivacaine (LEA 103). Acta Anaesthesiol Scand 1988; 32: 571-8
15. Cederholm I, Äkerman B, Evers H. Local analgesic and vascular effects of intradermal ropivacaine and bupivacaine in various concentrations with and without addition of adrenaline in man. Acta Anaesthesiol Scand 1994; 38: 322-7
16. Nolte H, Fruhstorfer H, Edström HH. Local anesthetic efficacy of ropivacaine (LEA 103) in ulnar nerve block. Reg Anesth 1990; 15: 118-24
17. Cederholm I, Anskär S, Bengtsson M. Sensory, motor and sympathetic blockade during epidural analgesia with 0.5% and 0.75% ropivacaine with and without epinephrine. Reg Anesth 1994; 19: 18-33
18. Hickey R, Candido K, Ramamurthy S, et al. Brachial plexus block with a new local anesthetic: 0.5% ropivacaine. Can J Anaesth 1990; 37: 732-8
19. Hickey R, Blanchard J, Hoffman J, et al. Plasma concentrations of ropivacaine given with or without epinephrine for brachial plexus block. Can J Anaesth 1990; 37: 878-82
20. Reiz S, Häggmark S, Johansson O, et al. Cardiotoxicity of ropivacaine; a new amide local anaesthetic agent. Acta Anaesthesiol Scand 1989; 33: 93-8
21. Feldman HS, Arthur GR, Covino BG. Comparative systemic toxicity of convulsant and supraconvulsant doses of intravenous ropivacaine, bupivacaine and lidiocaine in the conscious dog. Anesth Analg 1989; 69: 794-801
22. Nancarrow C, Rutten AJ, Runciman WB, et al. Myocardial and cerebral drug concentrations and the mechanisms of death after fatal intravenous doses of lidocaine, bupivacaine and ropivacaine in the sheep. Anesth Analg 1989; 69: 276-83
23. Moller R, Covino BG. Cardiac electrophysiologic properties of bupivacaine and lidocaine compared with those of ropivacaine, a new amide local anesthetic. Anesthesiology 1990; 72: 322-9
24. Scott DB, Lee A, Fagan D, et al. Acute toxicity of ropivacaine compared with that of bupivacaine. Anesth Analg 1989; 69: 563-9
25. Knudsen K, Beckman M, Blomberg S, et al. Central nervous and cardiovascular effects during intravenous infusions of ropivacaine, bupivacaine and placebo in healthy volunteers [abstract]. Int Monogr Reg Anesth 1995; Sep [Special abstract issue]: 15
26. Kopacz DJ, Emanuelsson BM, Thompson GE, et al. Pharmacokinetics of ropivacaine and bupivacaine for bilateral intercostal blockade in healthy male volunteers. Anesthesiology 1994; 81: 1139-48
27. Emanuelsson BM, Zaric D, Nydahl PA, et al. Pharmacokinetics of ropivacaine and bupivacaine during 21 hours of continuous epidural infusion in healthy male volunteers. Anesth Analg 1995; 81: 1163-8
28. van Kleef JW, Veering BT, Burm AG. Spinal anesthesia with ropivacaine: a double-blind study on the efficacy and safety of 0.5% and 0.75% solutions in patients undergoing minor lower limb surgery. Anesth Analg 1994; 78: 1125-30
29. McClure JH. Ropivacaine: review article. Br J Anaesth 1996; 76: 300-7
30. Santos AC, Arthur GR, Pedersen H, et al. Systemic toxicity of ropivacaine during ovine pregnancy. Anesthesiology 1991; 75: 137-41
31. Santos AC, Arthur GR, Wlody D, et al. Comparative systemic toxicity of ropivacaine and bupivacaine in nonpregnant and pregnant ewes. Anesthesiology 1995; 82: 734-40
32. Morishima HO, Pedersen H, Finster M, et al. Bupivacaine toxicity in pregnant and nonpregnant ewes. Anesthesiology 1985; 63: 134-9
33. Alahubta S, Rasanen J, Jouppila P, et al. The effects of epidural ropivacaine and bupivacaine for cesarean section on uteroplacental and fetal circulation. Anesthesiology 1995; 83: 23-32
34. Griffin RP, Reynolds F. Extradural anaesthesia for caesarean section: a double-blind comparison of 0.5% ropivacaine with 0.5% bupivacaine. Br J Anaesth 1995; 74: 512-6
35. Datta S, Camann W, Bader A, et al. Clinical effects and maternal and fetal plasma concentrations of epidural ropivacaine versus bupivacaine for cesarean section. Anesthesiology 1995; 82: 1346-52
36. McCrae AF, Jozwiak H, McClure JH. Comparison of ropivacaine and bupivacaine in extradural analgesia for the relief of pain in labour. Br J Anaesth 1995; 74: 261-5
37. Eddleston JM, Holland JJ, Griffin RP, et al. A double-blind comparison of 0.25% ropivacaine and 0.25% bupivacaine for extradural analgesia in labour. Br J Anaesth 1996; 76: 66-71
38. Stienstra R, Jonker TA, Bourdrez P, et al. Ropivacaine 0.25% versus bupivacaine 0.25% for continuous epidural analgesia in labor: a double-blind comparison. Anesth Analg 1995; 80: 285-9
39. Irestedt L, Ekblom A, Eriksson A-C, et al. Comparative actions and pharmacokinetics of ropivacaine and bupivacaine for epidural pain relief in labor [abstract]. Reg Anesth 1995; 20 Suppl. 2S: 68
40. Markham A, Faulds D. Ropivacaine: a review of its pharmacology and therapeutic use in regional anaesthesia. Drugs 1996; 52: 429-49
41. Zaric D, Nydahl P-A, Philipson L, et al. The effect of continuous lumbar epidural infusion of ropivacaine (0.1%, 0.2%, and 0.3%) and 0.25% bupivacaine on sensory and motor block in volunteers. Reg Anesth 1996; 21: 14-25
42. Zaric D. Quantitative methodological studies of motor and sensory blockade in epidural analgesia, with special reference to early mobilization and a new local anesthetic: ropivacaine [thesis]. Uppsala: University of Uppsala, 1995
43. Writer WD, Ahlen K, Hedlund C, et al. Ropivacaine compared to bupivacaine for epidural labour analgesia: a prospective meta-analysis [abstract]. International Symposium of Regional Anaesthesia: 1996 Apr 9-11; Auckland, New Zealand, 236
44. Schug SA, Scott DA, Payne S, et al. Postoperative analgesia by continuous extradural infusion of ropivacaine after upper abdominal surgery. Br J Anaesth 1996; 76: 487-91
45. Scott DA, Chamley DM, Mooney PH, et al. Epidural ropivacaine infusion for postoperative analgesia after major lower abdominal surgery; a dose finding study. Anesth Analg 1995; 81: 982-6
46. Finucaine BT, Yeh TW, O'Callaghan-Enright S, et al. Thoracic epidural infusions of ropivacaine (0.1, 0.2, 0.3%) vs placebo following upper abdominal surgery: a double-blind study [abstract]. Reg Anesth 1995; 20 Suppl. 2S: 35
47. Erichsen CJ, Sjövall J, Kehlet H, et al. Pharmacokinetics and analgesic effect of ropivacaine during continuous epidural infusion for postoperative pain relief. Anesthesiology 1996; 84: 834-42
48. Badner NH, Reid D, Sullivan P, et al. Continuous epidural infusion of ropivacaine for the prevention of postoperative pain after major orthopaedic surgery: a dose-finding study. Can J Anaesth 1996; 43: 17-22
49. Turner G, Blake D, Buckland M, et al. Continuous extradural infusion of ropivacaine for prevention of postoperative pain after major orthopaedic surgery. Br J Anaesth 1996; 76: 606-10
50. Johansson B, Glise H, Hallerback B, et al. Preoperative local infiltration with ropivacaine for postoperative pain relief after cholecystectomy. Anesth Analg 1994; 78: 210-4
51. Erichsen CJ, Vibits H, Dahl JB, et al. Wound infiltration with ropivacaine and bupivacaine for pain after inguinal herniotomy. Acta Anaesthesiol Scand 1995; 39: 67-70
52. Mulroy MF, Burgess KW, Carpenter RL, et al. Ropivacaine for postoperative wound infiltration following herniorrhaphy [abstract]. Anesthesiology 1994; 81 (3A): A1014
53. Stanton-Hicks M D' A. Cardiovascular effects of extradural anaesthesia. Br J Anaesth 1975; 47: 253-63
54. Covino BG. Cardiovascular effects of spinal and epidural anesthesia. Reg Anaesth 1978; 1: 23-6
55. Bengtsson M. Sensory and sympathetic blockade in connection with intradural and extradural analgesia. In: Löfström JB, Sjöstrand U, editors. Local anaesthesia and regional blockade, pharmacology, physiology and clinical effects. Amsterdam: Elsevier Science Publications, 1988: 105-33
56. Dahl JB, Simonsen L, Mogensen T, et al. The effect of 0.5% ropivacaine on epidural blood flow. Acta Anaesthesiol Scand 1990; 34: 308-10
57. Cederholm I, Evers H, Löfström JB. Skin blood flow after intradermal injection of ropivacaine in various concentrations with and without epinephrine evaluated by laser Doppler flowmetry. Reg Anesth 1992; 17: 322-8
58. Kopacz DJ, Carpenter RL, Mackey DC. Effect of ropivacaine on cutaneous capillary blood flow in pigs. Anesthesiology 1989; 71: 69-74
59. Nakamura K, Toda H, Kakuyama M, et al. Direct vascular effect of ropivacaine in femoral artery and vein of the dog. Acta Anaesthesiol Scand 1993; 37: 269-73
60. Gherardini G, Samuelson U, Jernbeck J, et al. Comparison of vascular effects of ropivacaine and lidocaine on isolated rings of human arteries. Acta Anaesthesiol Scand 1995; 39: 765-8