Effect of arachidonate on lipid metabolism in ethanol-treated rats fed with lard

Journal of Nutritional Science and Vitaminology

Volumn 43, Issue 3, 1997, Pages 311-326

  Okita, Misako ^a   Suzuki, Kazuhiko ^a   Sasagawa, Takayo ^a   Yamamoto, Junko ^b   Miyamoto, Ayumu ^c   Wakabayashi, Hiroyuki ^c   Watanabe, Akiharu ^c  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^b Chugoku Junior College   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

6 Keto prostaglandin F(1 ); Arachidonic acid ethyl ester; Ethanol feeding; Fatty acid

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ALANINE AMINOTRANSFERASE; ALCOHOL; ARACHIDONIC ACID; FATTY ACID; LARD; LEUKOTRIENE B4; LIPID; PHOSPHOLIPID; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FAT INTAKE; LIPID METABOLISM; LIVER; MALE; NONHUMAN; RAT;

ANIMALIA;

EID: 0030801458     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.43.311     Document Type: Article

References (27)

1. Reitz RC. 1993. Dietary fatty acid and alcohol: Effects on cellular membranes. Alcohol-Alcohol 28: 59-71.
2. Nakamura MT, Tang AB, Villanueva J, Halsted CH, Phinney SD. 1992. Reduced tissue arachidonic acid concentration with chronic ethanol feeding in miniature pigs. Am J Clin Nutr 56: 467-474.
3. Nakamura MT, Tang AB, Villanueva J, Halsted CH, Phinney SD. 1994. Selective reduction of Δ6 and Δ5 desaturase activities but not Δ9 desaturase in micropigs chronically fed ethanol. J Clin Invest 93: 450-454.
4. Goheen SC, Larkin EC, Ananda Rao G. 1983. Severe fatty liver in rats fed a fat-free ethanol diet, and its prevention by small amounts of dietary arachidonate. Lipids 18: 285-290.
5. Folch J, Lees M, Sloane-Stanley GH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509.
6. Okita M, Yoshida S, Yamamoto J, Suzuki K, Kaneyuki T, Kubota M, Sasagawa T. 1995. N-3 and n-6 fatty acid intake and serum phospholipid fatty acid composition in middle-aged women living in rural and urban areas in Okayama Prefecture. J Nutr Sci Vitaminol 41: 313-323.
7. Kawada N, Mizoguchi Y, Kobayashi K, Yamamoto S, Morisawa S. 1990. Arachidonic acid metabolites in carbon tetrachloride-induced liver injury. Gastroenterol Jpn 25: 363-368.
8. Lowry OH, Roseburge NJ, Farr AL, Randall RT. 1951. Protein measurement with Folin phenol reagent. J Biol Chem 193: 265-275.
9. Simpson KJ, Venkatesan S, Peters TJ. 1994. Fatty acid synthesis by rat liver after chronic ethanol feeding with a low-fat diet. Clin Sci 87: 441-446.
10. Smith TL, Vickers AE, Brendel K, Gerhart MJ. 1982. Effects of ethanol diets on cholesterol content and phospholipid acyl composition of rat hepatocytes. Lipids 17: 124-128.
11. Nanji AA, French SW. 1989. Dietary linoleic acid is required for development of experimental alcoholic liver disease. Life Sci 44: 223-227.
12. Salem N, Reyzer M, Karanian J. 1996. Losses of arachidonic acid in rat liver after alcohol inhalation. Lipids 31: s-153-s-156.
13. Wang DL, Reitz RC. 1983. Ethanol ingestion and polyunsaturated fatty acids: Effects on the acyl-CoA desaturases. Alcohol Clin Exp Res 7: 220-226.
14. Nanji AA, Hossein Sadrzadeh SM, Dannenberg A. 1994. Liver microsomal fatty acid composition in ethanol-fed rats: Effect of different dietary fats and relationship to liver injury. Alcohol Clin Exp Res 18: 1024-1028.
15. Zidenberg-Cherr S, Olin KL, Villanueva J, Tang A, Phinney SD, Halsted CH, Keen CL. 1991. Ethanol-induced changes in hepatic free radical defence mechanisms and fatty-acid composition in the miniature pig. Hepatology 13: 1185-1192.
16. Tsukamoto H, Lew G, Larkin EC, Largman C, Ro GA. 1984. Hepatic origin of triglycerides in fatty livers produced by the continuous intragastric infusion of an ethanol diet. Lipids 19: 419-422.
17. Whelan J, Surette ME, Li-Stiles B, Bailey JW. 1995. Evidence that dietary arachidonic acid increases circulating triglycerides. Lipids 30: 425-429.
18. Williams MA, Tinoco J, Yang Y-T, Bird MI, Hincenbergs I. 1989. Feeding pure docosahexaenoate or arachidonate decreases plasma triacylglycerol secretion in rats. Lipids 24: 753-758.
19. 2. Am J Pathol 142: 367-373.
20. Liu P, Kawada N, Mizoguchi Y, Morisawa S. 1992. Arachidonate metabolism in D-galactosamine or carbon tetrachloride-induced acute and chronic liver injuries in rats. Gastroenterol Jpn 27: 624-631.
21. Flisiak R, Boraona E, Li J, Lieber CS. 1993. Effects of ethanol on prostanoid production by liver fat-storing cells. Hepatology 18: 153-159.
22. 4-induced lipid peroxidation in rat liver and its significance for hepato-protection. Hepatology 9: 830-838.
23. Nanji AA, Khwaja S, Sadrzadeh H. 1994. Decreased prostacyclin production by liver non-parenchymal cells precedes liver injury in experimental alcoholic liver disease. Life Sci 54: 455-461.
24. Mann NJ, Warrick GE, O'Dea K, Knapp HR, Sinclair AJ. 1994. The effect of linoleic, arachidonic and eicosapentaenoic acid supplementation on prostacyclin production in rats. Lipids 29: 157-162.
25. Decker K. 1985. Eicosanoids, signal molecules of liver cells. Semin Liver Dis 5: 175-190.
26. Keppler D, Hagmann W, Rapp S, Denzlinger C, Koch HK. 1985. The relation of leukotrienes to liver injury. Hepatology 5: 883-891.
27. Chedid A, Mendenhall CL, Moritz TE, French SW, Chen TS, Morgan TR, Roselle GA, Nemchausky BA, Tamburro CH, Schiff ER, McClain CJ, Marsano LS, Allen JI, Samanta A, Weesner RE, Henderson WG, Veterans Affairs Cooperative Study Group 275. 1993. Cell-mediated hepatic injury in alcoholic liver disease. Gastroenterology 105: 254-266.