Retinol kinetics in the isolated retina determined by retinoid extraction and HPLC

Experimental Eye Research

Volumn 65, Issue 3, 1997, Pages 331-340

  Okajima, Ting Ing L ^a   Pepperberg, David R ^a,b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Photoreceptors; Retinoid visual cycle; Retinol dehydrogenase; Rhodopsin bleaching

Indexed keywords

RETINAL; RETINOL DEHYDROGENASE; RHODOPSIN;

ANIMAL TISSUE; ARTICLE; DARK ADAPTATION; HORMONE METABOLISM; LIGHT ADAPTATION; NONHUMAN; PHOTORECEPTOR; PHOTOTRANSDUCTION; PRIORITY JOURNAL; RETINA; TOAD;

EID: 0030800707     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1997.0331     Document Type: Article

References (47)

1. Adler, A. J., Evans, C. D. and Stafford, W. F., III. (1985). Molecular properties of bovine interphotoreceptor retinol-binding protein. J. Biol. Chem. 260, 4850-5.
2. Baumann, C. (1972). Kinetics of slow thermal reactions during the bleaching of rhodopsin in the perfused frog retina. J. Physiol. 222, 643-63.
3. Baumann, C. and Reinheimer, R. (1973). Temperature dependence of slow thermal reactions during the bleaching of rhodopsin in the frog retina. In Biochemistry and physiology of visual pigments (Ed. Langer, H.), Pp. 89-99. Springer-Verlag : New York, NY, U.S.A.
4. Bennett, N. and Sitaramayya, A. (1988). Inactivation of photoexcited rhodopsin in retinal rods: the roles of rhodopsin kinase and 48-kDa protein (arrestin). Biochemistry 27, 1710-15.
5. Blazynski, C. and Ostroy, S. E. (1984). Pathways in the hydrolysis of vertebrate rhodopsin. Vis. Res. 24, 459-70.
6. Bridges, C. D. B. (1976). Vitamin A and the role of the pigment epithelium during bleaching and regeneration of rhodopsin in the frog eye. Exp. Eye Res. 22, 435-55.
7. Brin, K. P. and Ripps, H. (1977). Rhodopsin photoproducts and rod sensitivity in the skate retina. J. Gen. Physiol. 69, 97-120.
8. Broekhuyse, R. M., Tolhuizen, E. F. J., Janssen, A. P. M. and Winkens, H. J. (1985). Light induced shift and binding of S-antigen in retinal rods. Curr. Eye Res. 4, 613-18.
9. Chen, Y. and Noy, N. (1994). Retinoid specificity of interphotoreceptor retinoid-binding protein. Biochemistry 33, 10658-65.
10. Crouch, R. K., Chader, G. J., Wiggert, B. and Pepperberg, D. R. (1996). Retinoids and the visual process. Photochem. Photobiol. 64, 613-21.
11. Donner, K. O. and Reuter, T. (1969). The photoproducts of rhodopsin in the isolated retina of the frog. Vis. Res. 9, 815-47.
12. Dowling, J. E. (1960). Chemistry of visual adaptation in the rat. Nature 188, 114-8.
13. Ernst, W., Kemp, C. M. and White, H. A. (1978). Studies on the effects of bleaching amphibian rod pigments in situ. II. The kinetics of the slow bleaching reactions in axolotl red rods. Exp. Eye Res. 26, 337-50.
14. Fukada, Y. and Yoshizawa, T. (1981). Activation of phosphodiesterase in frog rod outer segment by an intermediate of rhodopsin photolysis. II. Biochim. Biophys. Acta 675, 195-200.
15. Futterman, S. (1963). Metabolism of the retina. III. The role of reduced triphosphopyridine nucleotide in the visual cycle. J. Biol Chem. 238, 1145-50.
16. Hárosi, F. (1975). Absorption spectra and linear dichroism of some amphibian photoreceptors. J. Gen. Physiol. 66, 357-82.
17. Ho, M.-T. P., Massey, J. B., Pownall, H. J., Anderson, R. E. and Hollyfield, J. G. (1989). Mechanism of vitamin A movement between rod outer segments, interphotoreceptor retinoid-binding protein, and liposomes. J. Biol. Chem. 264, 928-35.
18. Hofmann, K. P., Pulvermüller, A., Buczylko, J., Van Hooser, P. and Palczewski, K. (1992). The role of arrestin and retinoids in the regeneration pathway of rhodopsin. J. Biol. Chem. 267, 15701-6.
19. Hollyfield, J. G., Fliesler, S. J., Rayborn, M. E., Fong, S.-L., Landers, R. A. and Bridges, C. D. (1985). Synthesis and secretion of interstitial retinol-binding protein by the human retina. Invest. Ophthalmol. Vis. Sci. 26, 58-67.
20. Hubbard, R., Brown, P. K. and Bownds, D. (1971). Methodology of vitamin A and visual pigments. Meth. Enzymol. 18, 615-53.
21. Ishiguro, S., Suzuki, Y., Tamai, M. and Mizuno, K. (1991). Purification of retinol dehydrogenase from bovine retinal rod outer segments.J. Biol. Chem. 266, 15520-4.
22. Jäger, S., Palczewski, K. and Hofmann, K. P. (1996). Opsin/all-trans retinal complex activates transducin by different mechanisms than photolyzed rhodopsin. Biochemistry 35, 2901-8.
23. Langlois, G., Chen, C.-K., Palczewski, K., Hurley, J. B. and Vuong, T. M. (1996). Responses of the phototransduction cascade to dim light. Proc. Natl. Acad. Sci. U.S.A. 93, 4677-82.
24. i. J. Gen. Physiol. 107, 19-34.
25. Mangini, N. J., Garner, G. L., Okajima, T.-I. L., Donoso, L. A. and Pepperberg, D. R. (1994). Effect of hydroxylamine on the subcellular distribution of arrestin (S-antigen) in rod photoreceptors. Vis. Neurosci. 11, 561-8.
26. Mangini, N. J. and Pepperberg, D. R. (1988). Immunolocalization of 48K in rod photoreceptors: light and ATP increase OS labeling. Invest. Ophthalmol. Vis. Sci. 29, 1221-34.
27. McGinnis, J. F., Whelan, J. P. and Donoso, L. A. (1992). Transient, cyclic changes in mouse visual cell gene products during the light-dark cycle. J. Neurosci. Res. 31, 584-90.
28. Ohguro, H., Rudnicka-Nawrot, M., Buczylko, J., Zhao, X., Taylor, J. A., Walsh, K. A. and Palczewski, K. (1996). Structural and enzymatic aspects of rhodopsin phosphorylation. J. Biol. Chem. 271, 5215-24.
29. Okajima, T.-I. L., Pepperberg, D. R., Ripps, H., Wiggert, B. and Chader, G. J. (1989). Interphotoreceptor retinoid-binding protein: role in delivery of retinol to the pigment epithelium. Exp. Eye Res. 49, 629-44.
30. Okajima, T.-I. L., Pepperberg, D. R., Ripps, H., Wiggert, B. and Chader, G. J. (1990). Interphotoreceptor retinoid-binding protein promotes rhodopsin regeneration in toad photoreceptors. Proc. Natl. Acad. Sci. U.S.A. 87, 6907-11.
31. Okajima, T.-I. L., Wiggert, B., Chader, G. J. and Pepperberg, D. R. (1994). Retinoid processing in retinal pigment epithelium of toad (Bufo marinus). J. Biol. Chem. 269, 21983-9.
32. Palczewski, K., Jäger, S., Buczyłko, J., Crouch, R. K., Bredberg, D. L., Hofmann, K. P., Asson-Batres, M. A. and Saari, J. C. (1994). Rod outer segment retinol dehydrogenase : substrate specificity and role in phototransduction. Biochemistry 33, 13741-50.
33. Palczewski, K., McDowell, J. H., Jakes, S., Ingebritsen, T. S. and Hargrave, P. A. (1991). Regulation of rhodopsin dephosphorylation by arrestin. J. Biol. Chem. 264, 15770-3.
34. Pepperberg, D. R., Cornwall, M. C., Kahlert, M., Hofmann, K. P., Jin, J., Jones, G. J. and Ripps, H. (1992). Light-dependent delay in the falling phase of the retinal rod photoresponse. Vis. Neurosci. 8, 9-18.
35. Pepperberg, D. R. and Okajima, T.-I. L. (1995). Quantitation of retinoids in unbleached vs. bleached isolated retina. Invest. Ophthalmol. Vis. Sci. 36, S124 (Abstr.)
36. Pittler, S. J., Fliesler, S. J. and Baehr, W. (1992). Primary structure of frog rhodopsin. FEBS Lett. 313, 103-8.
37. Rando, R. R. (1992). Molecular mechanisms in visual pigment regeneration. Photochem. Photobiol. 56, 1145-56.
38. Redmond, T. M., Wiggert, B., Robey, F. A., Nguyen, N. Y., Lewis, M. S., Lee, L. and Chader, G. J. (1985). Isolation and characterization of monkey interphotoreceptor retinoid-binding protein, a unique extracellular matrix component of the retina. Biochemistry 24, 787-93.
39. Saari, J. C. (1994). Retinoids in photosensitive systems. In The retinoids: biology, chemistry, and medicine, Second Edition (Eds Sporn, M. B., Roberts, A. B. and Goodman, D. S.), Pp. 351-85. Raven Press: New York, NY, U.S.A.
40. Saari, J. C., Bredberg, D. L., Garwin, G. G., Buczyłko, J., Wheeler, T. and Palczewski, K. (1993). Assays of retinoid dehydrogenase by phase partition. Analyt. Biochem. 213, 128-32.
41. Saari, J. C., Teller, D. C., Crabb, J. W. and Bredberg, L. (1985). Properties of an interphotoreceptor retinoid-binding protein from bovine retina. J. Biol. Chem. 260, 195-201.
42. Sears, R. C. and Kaplan, M. W. (1989). Axial diffusion of retinol in isolated frog rod outer segments following substantial bleaches of visual pigment. Vis. Res. 29, 1485-92.
43. Stryer, L. (1991). Visual excitation and recovery. J. Biol. Chem. 266, 10711-14.
44. Suzuki, T., Fujita, Y., Noda, Y. and Miyata, S. (1986). A simple procedure for the extraction of the native chromophore of visual pigments: the formaldehyde method. Vis. Res. 26, 425-9.
45. Suzuki, T., Maeda, Y., Toh, Y. and Eguchi, E. (1988). Retinyl and 3-dehydroretinyl esters in the crayfish retina. Vis. Res. 28, 1061-70.
46. Wilden, U., Hall, S. W. and Kühn, H. (1986). Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Proc. Natl. Acad. Sci. U.S.A. 83, 1174-8.
47. Zimmerman, W. F. (1974). The distribution and proportions of vitamin A compounds during the visual cycle in the rat. Vis. Res. 14, 795-802.