A laboratory approach to the evaluation of hereditary hypercoagulability

American Journal of Clinical Pathology

Volumn 108, Issue 4, 1997, Pages 434-449

  Adcock, Dorothy M ^a,b   Fink, Louis ^c   Marlar, Richard A ^b,d  

^a University of Colorado Health Sciences Center   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Coagulation; Hypercoagulability; Thrombosis

Indexed keywords

ACTIVATED PROTEIN C; ANTITHROMBIN III; BLOOD CLOTTING FACTOR 5; COUMARIN ANTICOAGULANT; HOMOCYSTEINE; PROTEIN C; PROTEIN S;

COST EFFECTIVENESS ANALYSIS; FAMILY HISTORY; GENE MUTATION; GENETIC DISORDER; HUMAN; HYPERCOAGULABILITY; HYPERHOMOCYSTEINEMIA; LABORATORY TEST; ORAL DRUG ADMINISTRATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; PROTEIN S DEFICIENCY; REVIEW; RISK FACTOR; SKIN NECROSIS; VEIN THROMBOSIS;

EID: 0030798660     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/108.4.434     Document Type: Review

References (9)

1. Hirsh J, Hoak J. Management of deep vein thrombosis and pulmonary embolism. Circulation. 1996;93:2212-2245.
2. van den Belt AGM, Prins MH, Huisman MV, Hirsh J. Familial thrombophilia: a review analysis. Clin Appl Thromb Hemost. 1996;2:227-236.
3. DeStefano V, Finazzi G, Mannucci PM. Inherited thrombophilia: pathogenesis, clinical syndromes, and management. Blood. 1996;87:3531-3544.
4. Hirsh J, Prins MH, Samama M. An approach to the thrombophilic patient. In: Colman RW, Hirsh J, Marder VJ, Salzman EW, eds. Hemostasis and Thrombosis: Basic Principles and Clinical Practice. Philadelphia, Pa: JB Lippincott; 1994:1543-1561.
5. Lewis R. Multifactorial traits. In: Human Genetics: Concepts and Applications. Dubuque, Iowa: WC Brown Publishers; 1994:93-109.
6. Bertina RM, Koeleman BPC, Koster T, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature. 1994;369:64-67.
7. Greengard JS, Xi S, Xiao X, Fernandez JA, Griffin JH, Evatt B. Activated protein C resistance caused by Arg 506Gln mutation in factor V. Lancet. 1994;343:1361-1362.
8. 506 of factor V. Lancet. 1994;343:1536.
9. Zöller B, Svensson PJ, He X, Dahlbäck B. Identification of the same factor V gene mutation in 47 out of 50 thrombosisprone families with inherited resistance to activated protein C. J Clin Invest. 1994;94:2521-2524.