Brain and plasma levels of cocaine and benzoylecgonine in lead-exposed and cadmium-exposed rats following acute or chronic intraperitoneal administration of cocaine

Toxicology Letters

Volumn 92, Issue 1, 1997, Pages 47-57

  Nation, Jack R ^a   Wellman, Paul J ^a   Livermore, Christina L ^a   Miller, Dennis K ^a   Bratton, Gerald R ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Cadmium; Cocaine; Lead; Pharmacokinetics

Indexed keywords

BENZOYLECGONINE; CADMIUM; COCAINE; LEAD ACETATE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; BRAIN LEVEL; CONTROLLED STUDY; DOSE RESPONSE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; TOXICOLOGY;

ANIMALS; BODY WEIGHT; BRAIN; CADMIUM CHLORIDE; COCAINE; CORPUS STRIATUM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EATING; INJECTIONS, INTRAPERITONEAL; MALE; NARCOTICS; NUCLEUS ACCUMBENS; ORGANOMETALLIC COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030797339     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)00033-7     Document Type: Article

References (30)

1. Blum, K., Cull, J.G., Braverman, E.R., Comings, D.E., 1996. Reward deficiency syndrome. Amer. Scient. 84, 132-145.
2. Busselberg, D., Michael, D., Platt, B., 1994. Pb2+ reduces voltage- and N-methyl-D-aspartate (NMDA)-activated calcium channel currents. Cell Mol. Neurobiol. 14, 711-722.
3. Cass, W.A., Zahniser, N.R., 1993. Cocaine levels in striatum and nucleus accumbens: augmentation following challenge injection in rats withdrawn from repeated cocaine administration. Neurosci. Lett. 152, 177-180.
4. Centers for Disease Control (CDC), 1991. Preventing lead poisoning in young children: A statement by the Centers for Disease Control. Atlanta, CDC.
5. Cory-Slechta, D.A., Widzowski, D.V., 1991. Low level lead exposure increases sensitivity to the stimulus properties of dopamine D1 and D2 agonists. Brain Res. 553, 65-74.
6. Costall, B., Naylor, R.J., 1977. Mesolimbic and extrapyramidal sites for the mediation of stereotyped behavior patterns and hyperactivity by amphetamine and apomorphine in the rat. In: Ellinwood, E.H. Jr., Kilbey, M.M. (Eds.), Cocaine and other stimulants, Advances in Behavioral Biology, Vol. 21. Plenum, New York, pp. 47-76.
7. Crouch, D.J, Alburges, M.E., Spanbauer, A.C., Rollins, D.E., Moody, D.E., 1995. Analysis of cocaine and its metabolites from biological specimens using solid-phase extraction and positive ion chemical ionization mass spectrometry. J. Anal. Toxicol. 19, 352-358.
8. Grace, A.A., 1995. The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcoh. Depend. 37, 111-129.
9. Grover, C.A., Nation, J.R., Bratton, G.R., 1993. Chronic exposure to lead attenuates cocaine-induced behavioral activation. Pharmacol. Biochem. Behav. 44, 221-225.
10. Ho, B.T., Taylor, D.L., Estevez, V.S., Englert, L/F., McKenna, M.L., 1977. Behavioral effects of cocaine: a metabolic and neurochemical approach. In: Ellinwood, E.H. Jr., Kilbey, M.M. (Eds.), Cocaine and other stimulants, Advances in Behavioral Biology, Vol. 21. Plenum, New York, pp. 229-240.
11. Kalivas, P.W., 1995. Interactions between dopamine and excitatory amino acids in behavioral sensitization to psychostimulants. Drug Alcoh. Depend. 37, 95-100.
12. Lasley, S.M., 1992. Regulation of dopaminergic activity, but not tyrosine hydroxylase is diminished after chronic inorganic lead exposure. Neurotoxicol. 13, 625-636.
13. Lasley, S.M., Lane, J.D., 1988. Diminished regulation of mesolimbic dopaminergic activity in the rat after chronic lead exposure. Toxicol. Appl. Pharmacol. 95, 474-483.
14. Legendre, P., Westbrook, G.L., 1990. The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurons. J. Physiol. 429, 429-449.
15. Maranelli, G., Apostoli, P., Ferrari, P., 1990. Influence of smoking, alcohol, and dietary habits on blood Pb and Cd levels. Bull. Environ. Contam. Toxicol. 45, 804-810.
16. Nation, J.R., Burkey, R.T., 1994. Attenuation of cocaine-induced elevation of nucleus accumbens dopamine in lead-exposed rats. Brain Res. Bull. 35, 101-104.
17. Nation, J.R., Grover, C.A., Salinas, J.A., Pugh, C.K., Peltier, R., Horger, B., Bratton, G.R., 1991. Effects of cadmium on cocaine-induced changes in activity. Behav. Neurosci. 105, 998-1003.
18. Nation, J.R., Livermore, C.L., Bratton, G.R., 1995. Cadmium exposure attenuates the initiation of behavioral sensitization to cocaine. Brain Res. 702, 223-232.
19. Nation, J.R., Livermore, C.L., Bratton, G.R., Schenk, S., 1996a. Chronic cadmium exposure alters cocaine self-administration in adult male rats. Exp. Clin. Psychopharmacol. 4, 264-270.
20. Nation, J.R., Livermore, C.L., Burkey, R.T., 1996b. Chronic lead exposure attenuates sensitization to the locomotor-stimulating effects of cocaine. Drug Alcoh. Depend. 41, 143-149.
21. 3H]cocaine in acutely and chronically treated rats. J. Pharmacol. Exp. Ther. 196, 556-569.
22. Olivier, V., Guibert, B., Leviel, V., 1995. Direct in vivo comparison of two mechanisms releasing dopamine in the rat striatum. Brain Res. 695, 1-9.
23. Pan, H., Menacherry, S., Justice, J.B., 1991. Differences in pharmacokinetics of cocaine in naive and cocaine-experienced rats. Neurochem. 56, 1299-1306.
24. Pettit, H.O., Pettit, A.J., 1994. Disposition of cocaine in blood and brain after a single pretreatment. Brain Res. 651, 261-268.
25. Reith, M.E.A., Benuck, M., Lajtha, A., 1987. Cocaine disposition in the brain after continuous or intermittent treatment and locomotor stimulation in mice. J. Pharmacol. Exp. Ther. 243, 281-287.
26. Ritz, M.C., Lamb, R.J., Goldberg, S.R., Kuhar, M.J., 1987. Cocaine receptors on dopamine transporters are related to self-administration of cocaine. Science 237, 1219-1223.
27. Robinson, S.E., Enters, E.K., Jackson, G.F., Chinchilli, V.M., Maher, J.R., McDowell, K.P., Allen, H.M., Guo, H., 1994. Maternal and fetal brain and plasma levels of cocaine and benzoylecgonine after acute and chronic maternal intravenous administration of cocaine. J. Pharmacol. Exp. Ther. 271, 1234-1239.
28. Schenk, S., Valadez, A., Worley, C.M., McNamara, C., 1993. Blockade of acquisition of cocaine self-administration by the NMDA antagonist MK-801 (dizocilpine). Behav. Pharmacol. 4, 652-659.
29. Spear, L.P., Frambes, N.A., Kirstein, C.L., 1989. Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following subcutaneous administration of cocaine during gestation in rats. Psychopharmacol. 97, 427-431.
30. Wise, R.A., Bozarth, M.A., 1987. A psychomotor stimulant theory of addiction. Psychol. Rev. 94, 469-492.