Cleavage of collagen RNA transcripts by hammerhead ribozymes in vitro is mutation-specific and shows competitive binding effects

Nucleic Acids Research

Volumn 25, Issue 17, 1997, Pages 3451-3458

  Grassi, Gabriele ^a   Forlino, Antonella ^a   Marini, Joan C ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; MESSENGER RNA; RIBOZYME;

ARTICLE; BINDING COMPETITION; CASE REPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENE MUTATION; HUMAN; OSTEOGENESIS IMPERFECTA; POINT MUTATION; PRIORITY JOURNAL; RNA CLEAVAGE;

ANIMALS; BASE SEQUENCE; BINDING, COMPETITIVE; COLLAGEN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE THERAPY; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; MUTATION; OSTEOGENESIS IMPERFECTA; POINT MUTATION; RNA; RNA, CATALYTIC;

EID: 0030796853     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.17.3451     Document Type: Article

References (28)

1. Kohn, D.B., Anderson, W.F. and Blaese, R.M. (1989) Cancer Invest. 7, 179-192.
2. Grassi, G. and Marini, J.C. (1996) Ann. Med. 28, 499-510.
3. Wang, Q. and Marini, J.C. (1996) J. Clin. Invest. 97, 448-454.
4. Marini, J.C. (1988) Adv. Pediatr. 35, 391-426.
5. Byers, P.H. (1993) In P.M. Royce and Steinmann, B., ed., Connective Tissue and its Heritable Disorders. John Wiley & Sons, New York, pp. 317-350.
6. Willing, M.C., Deschenes, S.P., Slayton, R.L. and Roberts, E. (1996) Am. J. Hum. Genet. 59, 799-809.
7. Melton, D.A. (1985) Proc. Natl. Acad. Sci. USA 82, 144-148.
8. Inouye, M. (1988) Gene 72, 25-34.
9. Rossi, J.J. (1995) Trends Biotechnol. 13, 301-306.
10. Sun, L.Q., Pyati, J., Smythe, J., Wang, L., MacPherson, J., Gerlach, W. and Symonds, G. (1995) Proc. Natl. Acad. Sci. USA 92, 7272-7276.
11. Zhou, C., Bahner, I.C., Larson, G.P., Zaia, J.A., Rossi, J.J. and Kohn, D.B (1994) Gene 149, 33-39.
12. Haseloff, J.G.W. and Gerlach, W.L. (1988) Nature 334, 585-591.
13. Ruffner, D.E., Stormo, G.D. and Uhlenbeck, O.C. (1990) Biochemistry 29, 10695-10702.
14. Symons, R.H. (1992) Annu. Rev. Biochem. 61, 641-671.
15. Bruening, G. (1990) Methods Enzymol. 180, 546-558.
16. Forster, A.C. and Symons, R.H. (1987) Cell 49, 211-220.
17. Perriman, R., Delves, A. and Gerlach, W.L. (1992) Gene 113, 157-163.
18. Zoumadakis, M. and Tabler, M. (1995) Nucleic Acids Res. 23, 1192-1196.
19. Wang, Q., Orrison, B.N. and Marini, J.C. (1993) J. Biol. Chem. 268, 25162-25167.
20. Wang, Q., Forlino, A. and Marini, J.C. (1996) J. Biol Chem. 271, 28617-28623.
21. Chomcynski, P. and Sacchi, N. (1987) Anal. Biochem. 162, 156-159.
22. Uhlenbeck, O.C. (1987) Nature 328, 596-600.
23. Kilpatrick, M.W., Phylactou, L.A., Godfrey, M., Wu, C.H., Wu, G.Y. and Tsipouras, P. (1996) Hum. Mol. Genet. 5, 1939-1944.
24. Bertrand, E.L. and Rossi, J.J. (1994) EMBO J. 13, 2904-2912.
25. Tsuchihashi, Z., Khosla, M. and Herschlag, D. (1993) Science 262, 99-102.
26. Papaphilis, A.D., Kamper, E.F., Grammenou, S., Kattamis, C. and Pangalis, G.A. (1990) Anticancer Res. 10, 1201-1212.
27. Wemer, M. and Uhlenbeck, O.C. (1995) Nucleic Acids Res. 23, 2092-2096.
28. Hertel, K.J., Herschlag, D. and Uhlenbeck, O.C. (1996) EMBO J. 15, 3751-3757.