A ring opening rearrangement reaction of 6β-hydroxytropinone

Tetrahedron Letters

Volumn 38, Issue 39, 1997, Pages 6823-6824

  Chen, Zhengming ^a   Gonzalez, Mario D ^a   Blundell, Paul ^a   Meltzer, Peter C ^a  

^a ORGANIX INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6BETA HYDROXYTROPINONE; OXAZOLIDINE DERIVATIVE; TROPANE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS;

EID: 0030796702     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01604-3     Document Type: Article

References (11)

1. Lautens, M. Synlett 1993, 177.
2. Momose, T.; Ṫoshima, M.; Seki, S.; Koike, Y.; Toyooka, N.; Hirai, Y. J. Chem. Soc., Perkin Trans. 1, 1997, 1307.
3. Momose, T.; Toshima, M.; Toyooka, N.; Hirai, Y.; Eugster, C. H. J. Chem. Soc., Perkin Trans. 1, 1997, 1315.
4. Majewski, M.; Lazny, R. Synlett 1996, 785.
5. Chen, Z.; Meltzer, P. C., Tetrahedron Lett. 1997, 38, 1121.
6. Syntheses of 6β-hydroxytropinone have been reported: a) Sheehan, J. C.; Bloom, B. M. J. Am. Chem. Soc. 1952, 74, 3825.
7. b) Murr, B. L.; Parkhill, B. J.; Nickon, A. Tetrahedron. 1992, 48, 4845.
8. Greene, T. W.: Wuts, P. G. M. in Protective Groups in Organic Synthesis. John Wiley and Sons, Inc.: New York, 1991, p 17.
9. 3), δ 209.1, 72.2, 63.6, 58.6, 44.5, 39.3, 38.4, 35.9.
10. Fodor, G; Chastain, R. V.; Frehel, D.: Cooper, M. J.; Mandava, N.; and Gooden, E. J. Am. Chem. Soc. 1971, 93, 403.
11. Bergmann, E. D. Chem. Rev. 1953, 53, 309.