Will the 'good fairies' please prove to us that vitamin E lessens human degenerative disease?

Free Radical Research

Volumn 26, Issue 6, 1997, Pages 565-583

  Diplock, Anthony T ^a  

^a GUY S HOSPITAL   (United Kingdom)

Author keywords

Human degenerative disease; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; FREE RADICAL; LIPOPROTEIN; MEMBRANE LIPID; OXYGEN RADICAL; UNSATURATED FATTY ACID;

AGING; ANTIOXIDANT ACTIVITY; ARTERIOSCLEROSIS; CANCER; CARCINOGENESIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; DEGENERATIVE DISEASE; DIET SUPPLEMENTATION; DIETARY INTAKE; DNA DAMAGE; HUMAN; ISCHEMIC HEART DISEASE; LIPID PEROXIDATION; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; QUALITY OF LIFE; REVIEW;

EID: 0030792848     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.3109/10715769709097827     Document Type: Review

References (85)

1. H. M. Evans (1962). The pioneer history of vitamin E. Vitamins and Hormones, 20, 379-387.
2. H. M. Evans, G. O. Burr and T. Althausen (1927). Memoirs University of California, 8, 1-23.
3. H. M. Evans and K. S. Bishop (1922). On the existence of a hitherto unrecognized dietary factor essential for reproduction. Science, 56, 650-651.
4. H. M. Evans and K. S. Bishop (1923). Existence of a hitherto unknown factor essential for reproduction. Journal of the American Medical Association, 81, 889-892.
5. E. Fernholtz (1937). Journal of the American Chemical Society, 59, 1154-1155.
6. E. Fernholtz (1938). Journal of the American Chemical Society, 60, 700-705.
7. P. Karrer, H. Fritzsche, B. H. Ringier and A. Salomon (1938). Helvetica Chimica Acta, 21, 820-825.
8. E. C. Slater, H. Rudney, J. Bouman and J. Links (1960). The possible role of α-tocopherol in the respiratory chain III. The tocopherol and ubiquinone content of heart-muscle preparation. Biochimica et Biophysica Acta, 47, 497-514.
9. H. Dam (1957). Influence of antioxidants and redox substances on signs of vitamin E deficiency. Pharmacological Reviews, 9, 1-16.
10. A. L. Tappel (1962). Vitamin E as the biological lipid antioxidant. Vitamins and Hormones, 20, 237-253.
11. A. K. Ghoshal and R. O. Recknagel (1967). Liver damage caused by carbon tetrachloride. Life Science, 4, 121-128.
12. M. Comporti (1985). Lipid peroxidation and cellular damage in toxic liver injury. Laboratory Investigation, 53, 599-614.
13. T. F. Slater and B. C. Sawyer (1971). The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum. Biochemical Journal, 123, 815-821.
14. T. F. Slater and B. C. Sawyer (1971). The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Inhibitory effects of free-radical scavengers and other agents. Biochemical Journal, 123, 823-828.
15. T. F. Slater and B. C. Sawyer (1971). The stimulatory effects of carbon tetrachloride and other halogenoalkanes on peroxidative reactions in rat liver fractions in vitro. Biochemical Journal, 123, 805-814.
16. J. Green, J. Bunyan, M. A. Cawthorne and A. T. Diplock (1969). Vitamin E and hepatotoxic agents.1. Carbon tetrachloride and lipid peroxidation in the rat. British Journal of Nutrition, 23, 297-307.
17. J. Bunyan, M. A. Cawthorne, A. T. Diplock and J. Green (1969). Vitamin E and hepatotoxic agents.2.Lipid peroxidation and poisoning with orotic acid, ethanol and thioacetamide in rats. British Journal of Nutrition, 23, 309-317.
18. C. A. Rice-Evans (1994). Formation of free radicals and mechanisms of action in normal biochemical processes and pathological states, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdons, Editors. Elsevier: Amsterdam, London, New York and London. p. 129-151.
19. B. Babior (1978). New England Journal of Medicine, 298, 659-668.
20. A. Cross and O. G. Jones (1991). Review. Enzymic mechanisms of superoxide production. Biochimica et Biophysica Acta, 1057, 281-291.
21. S. Moncada, R. M. J. Palmer and E. A. Higgs (1990). Relationship between prostacyclin and nitric oxide in the thrombotic process. Thrombosis Research, 11, 3-13.
22. B. Halliwell and J. M. C. Gutteridge (1989). Free Radicals in Biology and Medicine. 2nd ed. Oxford: Clarendon Press. 543.
23. A. T. Diplock (1992). The role of antioxidant nutrients in defence systems, in Encylopaedia of Food Science, Food Technology and Nutrition, R. Macrae, R. Robinson, and M. Sadlers, Editors. Academic Press: London. p. 211-216.
24. B. N. Ames, M. K. Shingenaga and E. M. Park (1991). DNA damage by endogenous oxidants as a cancer of aging and cancer in Oxidation Damage and Repair: Chemical, Biological and Medical Aspects, K. J. A. Davies, Editor. Pergamon: New York. p. 181-187.
25. B. Halliwell and O. I. Aruoma (1993). DNA and Free Radicals. New York, London: Ellis Horwood. p. 332.
26. B. N. Ames and M. K. Shigenaga, Oxidants are a major contributor to cancer and aging, in DNA and Free Radicals, B. Halliwell and O. I. Aruoma, Editors. Ellis Horwood: New York and London. p. 1-15.
27. L. Marnett, H. K. Hurd, M. K. Hollenstein, D. E. Levin, H. Esterbauer and B. H. Ames (1985). Naturally occurring carbonyl compounds and nutagens in Salmonella tester strain T A 104. Mutation Research, 148, 25-34.
28. H. Esterbauer, R. J. Schaur and H. Zollner (1991). Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and releted aldehydes. Free Radicals in Biology and Medicine, 11, 81-128.
29. M. Dizdaroglu (1993). Chemistry of free radical damage to DNA and nucleoproteins, in DNA and Free Radicals, B. Halliwell and O. I. Aruoma, Editors. Ellis Horwood: New York and London. p. 19-39.
30. R. Meneghini and E. L. Martins (1993). Hydrogen peroxide and DA damage, in DNA and Free Radicals, B. Haliwell and O. I. Aruoma, Editors. Ellis Horwood: New York and London. p. 83-93.
31. K. Thorsten and I. Romslo (1984). Uptake of iron from transferrin by isolated hepatocytes. Biochimica et Biophysica Acta, 804, 200-208.
32. H. Wiseman and B. Halliwell (1996). Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochemical Journal, 313, 17-29.
33. K. H. Cheeseman (1993). Lipid peroxidation and cancer, in DNA and Free Radicals, B. Halliwell and O. I. Aruoma, Editors. Ellis Horwood: New York and London. p. 109-144.
34. A. L. Tappel and C. J. Dillard (1981). In vivo lipid peroxidation: measurement via exhaled pentane and protection by vitamin E. Federation Proceedings, 40, 174-178.
35. H. Esterbauer (1985). Lipid peroxidation products. Formation chemical properties and biological activities. Free Radicals in Liver Injury, 29-47.
36. H. Esterbauer, E. Koller, P. Heckenast, R. Moser and C. Celotto (1987). Cytotoxic lipid peroxidation products. First Vienna Shock Forum, 245-252.
37. C Rice-Evans and K. R. Bruckdorfer (1992). Free radicals, lipoproteins and cardiovascular dysfunction. Molecular Aspects of Medicine, 13, 1-111.
38. A. L. Tappel (1955). Studies of the effects of free radical damage to proteins. Archives of Biochemistry and Biophysics, 54, 266-280.
39. E. R. Stadtman (1993). Oxidation of free amino acids and amino acid residues in proteins by radiolysis and by metal-catalyzed reactions. Annual Reviews of Biochemistry, 62, 797-821.
40. E. R. Stadtman (1992). Protein oxidation and aging. Science, 257, 1220-1224.
41. A. T. Diplock (1985). Fat soluble vitamins: their biochemistry and applications: Heinemann. p. 319.
42. A. T. Diplock and J. A. Lucy (1973). The biochemical modes of action of vitamin E and selenium: a hypothesis. FEBS Letters, 29, 205-210.
43. A. T. Diplock (1994). Antioxidants and free radical scavengers, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdon, Editor. Elsevier: Amsterdam, London, New York and Tokyo. p. 111-127.
44. G. W. Burton, U. Wronska, L. Stone, D. O. Foster and K. U. Ingold (1990). Biokinetics of dietary RRR-α-tocopherol in male guinea pigs at three dietary levels of vitamin C and vitamin E. Evidence that vitamin C does not "spare" vitamin E in vivo. Lipids, 25, 199-210.
45. J. C. FrucHart and P. Duriez (1944). Free radicals and atherosclerosis, in Free Radical Damage and Its Control, C. A. Rico-Evans and R. H. Burdon, Editors. Elsevier: Amsterdam, London, New York and Tokyo. p. 253-276.
46. B. Kalyanaraman, E. A. Konorev, J. Joseph and J. E. Baker (1994). Radical generation and detection in myocardial injury, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdon, Editors. Elsevier: Amserdam, London, New York and Tokyo. p. 329-355.
47. R. Burdon (1994). Free Radicals and cell proliferation, in Free Radical Damage and Its control, C. A. Rice-Evans and R. H. Burdons, Editors. Elsevier: Amsterdam, London, New York and Tokyo. p. 153-183.
48. P. F. Jacques and L. T. Chylack (1991). Epidemiological evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. American Journal of Clinical Nutrition, 53, 352S-355S.
49. P. Knekt, M. Heliovaara, A. Rissanen, A. Aromaa and R. K. Aaran (1992). Serum antioxidant vitamins and risk of cataract. British Medical Journal, 305(6866), 1392-4.
50. A. Taylor (1993). Cataract: relationship between nutrition and oxidation. Journal of the American College of Nutrition, 12(2), 138-16.
51. N. M. Finer, K. L. Peters, R. F. Schindler and G. D. Grant (1985). Vitamin E and retrolental fibroplasia, in Biology of Vitamin E, R. Porter and J. Whelan, Editors. Pitman: London. p. 147-164.
52. H. Hitner, F. L. Kretzer and A. J. Rudolph (1984). Prevention and managment of retrolental fibroplasia. Hospital Practice, 19, 85-99.
53. L. Johnson (1981). Retrolental fibroplasia: a new look at an unsolved problem. Hospital Practice, 109-121.
54. B. J. Parsons (1994). Chemical aspects of free radical reactions in connective tissue, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdon, Editors. Elsevier: Amsterdam, London, New York and Tokyo. p. 277-296.
55. P. G. Winyard, C. J. Morris, V. R. Winrow, M. Zaidi and D. R. Blake (1994). Free radical pathways in the inflammatory response, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdon, Editors. Elsevie: Amsterdam, London, New York and Tokyo. p. 357-379.
56. E. D. Hall (1994). Free radicals in central nervous system injury, in Free Radical Damage and Its Control, C. A. Rice-Evans and R. H. Burdon, Editors. Elsevier: Amsterdam, London, New York and Tokyo. p. 213-234.
57. R. Morrero and L. J. Marnett (1993). The role of organic peroxyl radicals in carcinogenesis, in DNA and Free Radicals, B. Halliwell and O. I. Aruoma, Editors. Ellis Horwood: New York and London. p. 145-161.
58. G. Barrera, C. D. Mauro, R. Maraca, D. Ferrero, G. Cavalli, V. M. Fazio, L. Paradisi and M. U. Dianzani, (1991). Experimental Cellular Research, 197, 148-152.
59. T. F. Slater, C. Benedetto, K. H. Cheeseman, M. Collins, M. J. Davies, S. Flatman, M. Hayashi, J. S. Hurst, R. G. McDonald-Gibson, A. Morgan, S. Nigam and K. Proudfoot (1986). in Free Radicals, Cell Damage and Disease, C. Rice-Evans, Editor. Reichlieu Press: London. p. 57-72.
60. U. P. Steinbrecher (1987). Oxidation of human low density lipoprotein results in derivatisation of lysine residues of apolipoprotein β by lipid peroxidation decomposition products. Journal of Biological Chemistry, 262, 3603-3608.
61. H. Esterbauer, M. Rotheneder, G. Striegl, G. Waeg, A. Ashy, W. Sattler and C. Jurgens (1989). Vitamin E and other lipophylic antioxidants protect LDL against oxidation. Fat Science and Technology, 91, 316-324.
62. R. W. Wissler (1978). in Atherosclerosis Reviews, R. Paoletti and A. M. Gottos, Editors. Raven Press: New York. p. 213-247.
63. D. H. Blankenhorn, S. A. Nessim, R. D. Johnson, M. E. Sammarco, S. P. Azen and L. Cashin-Hemphill (1987). Journal of American Medical Association, 257, 3233-.
64. G. Block and M. Menkes (1989). Ascorbic acid in cancer prevention, in Diet and cancer prevention: investigating the role of micronutrients, T. E. Moon and M. S. Micozzis, Editors. Marcel Dekker: New York. p. 341-388.
65. G. Block (1991). Vitamin C and cancer prevention: the epidemiologic evidence. American Journal of Clinical Nutrition, 53, 270S-282S.
66. R. G. Ziegler (1989). A review of epidemiologic evidence that carotenoids reduce the risk of cancer. Journal of Nutrition, 119, 116-122.
67. T. K. Basu, N. J. Temple and A. M. Hodgson (1988). Vitamin A, beta-carotene and cancer. Progress in Clinical Biological Research, 259, 255-267.
68. G. Block, B. Patterson and A. Subar (1992). Fruit vegetables and cancer prevention: a review of the epidemiological evidence. Nutrition and Cancer, 18, 1-29.
69. N. I. Ellis, B. Lloyd, R. S. Lloyd and B. E. Clayton (1984). Selenium and vitamin E in relation to risk factors for coronary heart disease. Journal of Clinical Pathology, 37, 200-6.
70. R. Cherniauskene, L. E. Margiavichene, Z. Z. Varshkiavichene and P. S. Gribauskas (1984). Vitamin E and serum lipids in ischemic heart disease (In Russian). Vopr Med Khim, 30, 102-5.
71. K. F. Gey (1986). On the antioxidant hypothesis with regard to arteriosclerosis. Bibliotheca Nutritica Dietetica, 37, 53-91.
72. M. K. Horwitt, C. C. Harvey, C. H. Dahm and M. T. Searcy (1972). Relationship between tocopherol and serum lipid levels for determination of nutritional adequacy. Annals of the New York Academy of Sciences, 203, 223-236.
73. WHO, (1989). World Health Organization. The WHO MONICA Project. World Health Statistics, 42, 27-149.
74. K. F. Gey, P. Puska, P. Jordan and U. K. Moser (1991). Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. American Journal of Clinical Nutrition, 53, 326S-334S.
75. R. A. Riemersma, D. A. Wood, C. C. Macintyre, R. A. Elton, K. F. Gey and M. F. Oliver (1991). Risk of angina pectoris and plasma concentrations of vitamins A, C, and E, and carotene. Lancet, 337, 1-5.
76. E. B. Rimm, M. J. Stampfer, A. Ascherio, E. Giovannucci, G. A. Colditz and W. C. Willett (1993). Vitamin E consumption and the risk of coronary heart disease in men. New England Journal of Medicine, 328, 1450-6.
77. M. J. Stampfer, C. H. Hennekens, J. E. Manson, G. A. Colditz, B. Rosner and W. C. Willett (1943). Vitamin E consumption and the risk of coronary disease in women. New England Journal of Medicine, 328, 1444-9.
78. J. T. Salonen, S. Yla-Herttuala, R. Yamamoto, S. Butler, H. Korpela, R. Salonen, K. Nyyssonen, W. Palinski and J. L. Witztum (1992). Autoantibody against oxidised LDL and progression of carotid atherosclerosis. The Lancet, 339, 883-888.
79. M. E. Haberland, D. Fong and L. Cheng (1988). Malondialdehyde-altered protein occurs in atheroma of Watanabe heritable hyperlipidaemic rabbits. Science, 241, 215-218.
80. H. C. Boyd, A. M. Gown, G. Wolfbauer and A. Chait (1989). Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanbe heritable hyperlipidaemic rabbit. American Journal of Pathology, 135, 815-825.
81. W. Palinski, M. E. Rosenfeld and S. Yla-Herrtuala (1989). Low density lipoprotoin undergoes oxidative modification in vivo. Proceedings of the National Academy of Science USA, 86, 1372-1376.
82. J. M. Gaziano, J. E. Manson, P. M. Ridker, J. E. Burling and C. E. Hennekens (1990). Beta carotene therapy for chronic stable angina. Circulation, 82, 201.
83. N. G. Stephens, A. Parsons, P. M. Schofield, F. Kelly, K. Cheeseman and M. J. Mitchinson (1996). Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet, 347, 781-6.
84. K. F. Gey, U. K. Moser, P. Jordan, H. B. Stahelin, M. Eichholzer and E. Ludin (1993). Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C. American Journal of Clinical Nutrition, 57, 787S-797S.
85. D. Steinberg (1993). Antioxidant vitamins and coronary heart disease [editorial; comment]. New England Journal of Medicine, 328, 1487-9.