Both T and B cells shed infectious mouse mammary tumor virus

Journal of Virology

Volumn 71, Issue 8, 1997, Pages 6044-6048

  Dzuris, John L ^a   Golovkina, Tatyana V ^a   Ross, Susan R ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BREAST CELL; CONTROLLED STUDY; MILK; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS SHEDDING; VIRUS TRANSMISSION;

EID: 0030787736     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.8.6044-6048.1997     Document Type: Article

References (21)

1. Acha-Orbea, H., and H. R. MacDonald. 1995. Superantigens of mouse mammary tumor virus. Annu. Rev. Immunol. 13:459-486.
2. Beutner, U., E. Draus, D. Kitamura, K. Rajewsky, and B. T. Huber. 1994. B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens. J. Exp. Med. 179:1457-1466.
3. Chirgwin, J. M., A. E. Prxybyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299.
4. Desaymard, C., C. L. Tucek, B. Rocha, A. J. Korman, and M. Papiernik. 1993. Tissue distribution of Mtv-7-like exogenous retroviral transcripts and clonal deletion of Vβ6+ T cells in M1s1b BALB/c mice. Int. Immunol. 5:217-222.
5. Golovkina, T. V., A. Chervonsky, J. P. Dudley, and S. R. Ross. 1992. Transgenic mouse mammary tumor virus superantigen expression prevents viral infection. Cell 69:637-645.
6. Golovkina, T. V., A. Chervonsky, J. A. Prescott, C. A. Janeway, and S. R. Ross. 1994. The mouse mammary tumor virus envelope gene product is required for superantigen presentation to T cells. J. Exp. Med. 179:439-446.
7. Golovkina, T. V., J. P. Dudley, A. Jaffe, and S. R. Ross. 1995. Mouse mammary tumor viruses with functional superantigen genes are selected during in vivo infection. Proc. Natl. Acad. Sci. USA 92:4828-4832.
8. Golovkina, T. V., A. Jaffe, and S. R. Ross. 1994. Coexpression of exogenous and endogenous mouse mammary tumor virus RNA in vivo results in viral recombination and broadens the virus host range. J. Virol. 68:5019-5026.
9. Golovkina, T. V., I. Piazzon, I. Nepomnaschy, V. Buggiano, M. de Olano Vela, and S. R. Ross. 1997. Generation of a tumorigenic milk-borne mouse mammary tumor virus by recombination between endogenous and exogenous viruses. J. Virol. 71:3895-3903.
10. + T cells are required to stimulate B cells after infection with mouse mammary tumor virus. J. Exp. Med. 177:359-366.
11. Held, W., G. Waanders, A. N. Shakhov, L. Scarpellino, H. Acha-Orbea, and H. Robson-MacDonald. 1993. Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission. Cell 74:529-540.
12. Held, W., G. A. Waanders, H. Acha-Orbea, and H. R. MacDonald. 1994. Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: implications for superantigen function. J. Exp. Med. 180:2347-2351.
13. Ignatowicz, L., J. Kappler, and P. Marrack. 1992. The effects of chronic infection with a superantigen-producing virus. J. Exp. Med. 175:917-923.
14. Karapetian, O., A. N. Shakhov, J.-P. Kraehenbuhl, and H. Acha-Orbea. 1994. Retroviral infection of neonatal Peyer's patch lymphocytes: the mouse mammary tumor virus model. J. Exp. Med. 180:1511-1516.
15. Nandi, S., and C. M. McGrath. 1973. Mammary neoplasia in mice. Adv. Cancer Res. 17:353-414.
16. Nusse, R., L. van der Ploeg, L. van Duijn, R. Michalides, and J. Hilgers. 1979. Impaired maturation of mouse mammary tumor virus precursor polypeptides in lymphoid leukemia cells, producing intracytoplasmic A particles and no extracellular B-type virions. J. Virol. 32:251-258.
17. Scherer, M. T., L. Ignatowicz, G. M. Winslow, J. W. Kappler, and P. Marrack. 1993. Superantigens: bacterial and viral proteins that manipulate the immune system. Annu. Rev. Cell Biol. 9:101-128.
18. Schochetman, G., L. O. Arthur, C. W. Long, and R. J. Massey. 1979. Mice with spontaneous mammary tumors develop type-specific neutralizing and cytotoxic antibodies against the mouse mammary tumor virus envelope protein gp52. J. Virol. 32:131-139.
19. Shackleford, G. M., and H. E. Varmus. 1988. Construction of a clonable, infectious, and tumorigenic mouse mammary tumor virus provirus and a derivative genetic vector. Proc. Natl. Acad. Sci. USA 85:9655-9659.
20. Tsubura, A., M. Inaba, S. Imai, A. Murakami, N. Oyaizu, R. Yasumizu, Y. Ohnishi, H. Tanaka, S. Morii, and S. Ikehara. 1988. Intervention of T-cells in transportation of mouse mammary tumor virus (milk factor) to mammary gland cells in vivo. Cancer Res. 48:6555-6559.
21. Waanders, G. A., A. N. Shakhov, W. Held, P. Karapetian, H. Acha-Orbea, and H. R. MacDonald. 1993. Peripheral T cell activation and deletion induced by transfer of lymphocyte subsets expressing endogenous or exogenous mouse mammary tumor virus. J. Exp. Med. 177:1359-1366.