Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells

Blood

Volumn 90, Issue 9, 1997, Pages 3735-3742

  Terpstra, Wim ^b   Rozemuller, Henk ^b   Breems, Dimitri A ^b   Rombouts, Elwin U C ^b   Prins, Arie ^b   Fitzgerald, David J P ^b   Kreitman, Robert J ^b   Wielenga, Jenne J ^b   Ploemacher, Rob E ^b   Löwenberg, Bob ^b   Hagenbeek, Anton ^b   Martens, Anton C M ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTILEUKEMIC AGENT; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; INTERLEUKIN 3; STEM CELL FACTOR; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CULTURE; BURST FORMING UNIT E; CELL KILLING; CELL PROLIFERATION; CLONOGENIC ASSAY; COLONY FORMING UNIT GM; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE;

EID: 0030781919     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.9.3735     Document Type: Article

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