Neuropharmacological assessment of growth hormone secretion

Acta Paediatrica, International Journal of Paediatrics, Supplement

Volumn 86, Issue 423, 1997, Pages 12-16

  Carro, E ^a   Senaris R ^a   Peino, R ^b   Leal Cerro, A ^b   Popovic, V ^c   Micic, D ^c   Dieguez, C ^a   Casanueva, F F ^a,d  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^c CLINICAL CENTER OF SERBIA   (Serbia)

^d NONE   (Spain)

Author keywords

Growth hormone secretagogue; Growth hormone releasing hormone; Growth hormone releasing peptide 6; Somatostatin

Indexed keywords

GROWTH HORMONE; GROWTH HORMONE RECEPTOR; GROWTH HORMONE RELEASING FACTOR; SOMATOSTATIN;

CONFERENCE PAPER; FEEDBACK SYSTEM; GROWTH HORMONE RELEASE; HYPOTHALAMUS; NUTRITIONAL STATUS; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0030781033     PISSN: 08035326     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (32)

1. Casanueva FF. Diagnosis of growth hormone deficiency in adulthood. Eur J Endocrinol 1996;135:168-70
2. Rosenfeld RG. Is growth hormone deficiency a viable diagnosis? (Editorial). J Clin Endocrinol Metab 1997;82:349-51
3. Marin G, Domene HM, Barnes KM, Blackwell BJ, Cassorla FG, Cutler GB. The effects of estrogen priming and puberty on the growth hormone response to standardized treadmill exercise and arginine-insulin in normal girls and boys. J Clin Endocrinol Metab 1994;79:537-41
4. Frohman LA. Cellular physiology of growth hormone releasing hormone. In: Bercu BB, Walker RF, editors. Growth hormone secretagogues. New York: Springer-Verlag, 1996:137-46
5. Howard AD, Feighner SD, Cully DF, Arena JP, Liberator PA, Rosenblum CI, et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science 1996;273:974-7
6. Bowers CY, Momany FA, Chang D, Hong A, Chang K. Structure-activity relationships of a synthetic pentapeptide that specifically releases GH in vitro. Endocrinology 1980;106:663-7
7. Bowers CY, Sartor AO, Reynolds GA, Badger TM. On the actions of the growth hormone-releasinc hexapeptide, GHRP-6. Endocrinology 1991;128:2027-35
8. Casanueva FF. Physiology of growth hormone secretion and action. Endocrinol Metab Clin North Am 1992;21:483-517
9. Dieguez C, Casanueva FF. Influence of metabolic substrates and obesity on growth hormone secretion. Trends Endocrinol Metab 1995;6:55-9
10. Tannenbaum GS, Ling N. The interrelationship of growth hormone (GH)-releasing hormone and somatostatin in generation of the ultradian rhythm of GH secretion. Endocrinology 1984;115:1952-7
11. Frohman LA. The role of hypothalamic hormones in the control of growth hormone secretion and of growth. Acta Paediatr Scand Suppl 1988;343:3-8
12. Robinson ICAF, Clark RG. The secretory pattern of GH and its significance for growth in the rat. In: Isaksson O, editor. Growth hormone, basic and clinical aspects. Amsterdam: Elsevier, 1987:109-27
13. Imaki T, Shibasaki T, Masuda A, Hotta M, Yamauchi N, Demura H, et al. The effect of glucose and free fatty acids on growth hormone (GH)-releasing factor-mediated GH secretion in rats. Endocrinology 1986;118:2390-4
14. Jaffe CA, De Mott R, Frohman LA, Barkan AL. Suppression of growth hormone (GH) hypersecretion due to ectopic GH-releasing hormone (GHRH) by a selective GHRH antagonist. J Clin Endocrinol Metab 1997;82:634-7
15. Burguera B, Muruais C, Peñalva A, Dieguez C, Casanueva FF. Dual and selective action of glucocorticoids upon basal and stimulated growth hormone release in man. Neuroendocrinology 1990;51:51-8
16. Casanueva FF, Buguera B, Muruais C, Dieguez C. Acute administration of corticoids: a new and peculiar stimulus of growth hormone secretion in man. J Clin Endocrinol Metab 1990;70:234-7
17. Martul P, Pineda J, Dieguez C, Casanueva FF. Corticoid-induced growth hormone (GH) secretion in GH deficient and normal children. J Clin Endocrinol Metab 1992;75:536-9
18. Pineda J, Martul P, Casanueva FF, Dieguez C, Rica I, Loridan L. Oral dexamethasone administration: a new pharmacological test for the assessment of growth hormone secretion. Eur J Endocrinol 1994;131:598-601
19. Vance, ML. Metabolic status and growth hormone secretion in man. J Paediatr Endocrinol 1993;6:3-4
20. Casanueva FF, Villanueva L, Dieguez C, Diaz Y, Cabranes JA, Szoke B, et al. Free fatty acids block growth hormone (GH) releasing hormone-stimulated GH secretion in man directly at the pituitary. J Clin Endocrinol Metab 1987;65:634-42
21. Alvarez CV, Mallo F, Burguera B, Cacicedo L, Dieguez C, Casanueva FF. Evidence for a direct pituitary inhibition by free fatty acids of in vivo growth hormone responses to growth hormone-releasing factor in the rat. Neuroendocrinology 1991;53:185-9
22. Casabiell X, Zugaza JL, Pombo CM, Pandiella A, Casanueva FF. Oleic acid blocks epidermal growth factor-activated early intracellular signals without altering the ensuing mitogenic response. Exp Cell Res 1993;205:365-73
23. 2+ release without altering cellular metabolism in fibroblast EGFR T17. Biochem Biophys Res Commun 1995;207:105-10
24. Peino R, Cordido F, Peñalva A, Alvarez CV, Dieguez C, Casanueva FF. Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli. J Clin Endocrinol Metab 1996;81:909-13
25. Pontiroli AE, Lanzi R, Monti LD, Sandoli E, Pozza G. Growth hormone (GH) auto feedback on GH response to GH-releasing hormone. Role of free fatty acids and somatostatin. J Clin Endocrinol Metab 1991;72:492-5
26. Leal A, Jimenez L, Astorga R, Fernandez J, Dieguez C, Casanueva FF. Acute pharmacological reduction of free fatty acids restored to normal the GHRH-mediated GH secretion in Cushing's syndrome. J Clin Endocrinol Metab 1997 (in press)
27. Peñalva A, Pombo M, Carballo A, Barreiro J, Casanueva FF, Dieguez C. Influence of sex, age and adrenergic pathways on the growth hormone response to GHRP-6. Clin Endocrinol 1993;38:87-91
28. Bowers CY, Reynolds GA, Durham D, Barrera CM, Pezzoli SS, Thorner MO. Growth hormone (GH)-releasing peptide stimulates GH release in normal men and acts synergistically with GH-releasing hormone. J Clin Endocrinol Metab 1990;70:975-82
29. Pombo M, Barreiro J, Peñalva A, Peino R, Dieguez C, Casanueva FF. Absence of growth hormone (GH) secretion after the administration of either GH-releasing hormone (GHRH), GH-releasing peptide (GHRP-6) or GURU plus GHRP-6, in children with neonatal pituitary stalk transection. J Clin Endocrinol Metab 1995;80:3180-4
30. Cordido F, Peñalva A, Dieguez C, Casanueva FF. Massive growth hormone (GH) discharge in obese subjects after the combined administration of GH-releasing hormone and GHRP-6: evidence for a marked somatotroph secretory capability in obesity. J Clin Endocrinol Metab 1993;76:819-23
31. Micic D, Popovic V, Kendereski A, Macut D, Casanueva FF, Dieguez C. Growth hormone secretion after the administration of GHRP-6, or GHRP-6 combined with GHRH does not decline in late adulthood. Clin Endocrinol 1995;42:191-4
32. Leal A, Garcia E, Astorga R, Casanueva FF, Dieguez C. Growth hormone (GH) responses to the combined administration of GH-releasing hormone plus GH-releasing peptide 6 in adults with GH deficiency. Eur J Endocrinol 1995;132:712-15