-
1
-
-
0029043838
-
Linkage of cardiac left - right asymmetry and dorso-anterior development in Xenopus
-
Danos MC, Yost HJ. Linkage of cardiac left - right asymmetry and dorso-anterior development in Xenopus. Development. 121:1995;1467-1474.
-
(1995)
Development
, vol.121
, pp. 1467-1474
-
-
Danos, M.C.1
Yost, H.J.2
-
2
-
-
0025364567
-
The development of handedness in left/right assembly
-
Brown NA, Wolpert L. The development of handedness in left/right assembly. Development. 109:1990;1-9.
-
(1990)
Development
, vol.109
, pp. 1-9
-
-
Brown, N.A.1
Wolpert, L.2
-
3
-
-
0001929568
-
Breaking symmetry: Left - right development in Xenopus laevis
-
E.B. Clark, R.R. Markwald, Takao A. Armonk, New York: Futura Publishing Co
-
Yost HJ. Breaking symmetry: left - right development in Xenopus laevis. Clark EB, Markwald RR, Takao A. Developmental Mechanisms of Heart Diseases. 1995;505-511 Futura Publishing Co, Armonk, New York.
-
(1995)
Developmental Mechanisms of Heart Diseases
, pp. 505-511
-
-
Yost, H.J.1
-
4
-
-
0030668717
-
Two molecular models of initial left - right asymmetry generation
-
The authors present two speculative models to explain how the asymmetric expression of certain genes is initiated in the process of L - R patterning in vertebrates. These hypotheses are based on experimental data suggesting two independent molecules as candidates for the primary steps of L - R determination: a dynein-like motor protein may transport a chiral determinant to one side of the cell, establishing a distinction between the right and the left sides. This cell asymmetry may then be used to establish broad cell fields of differential gene expression by a gap junction protein with asymmetric activity. of special interest
-
Levin M, Nascone N. Two molecular models of initial left - right asymmetry generation. of special interest Med Hyp. 1997; The authors present two speculative models to explain how the asymmetric expression of certain genes is initiated in the process of L - R patterning in vertebrates. These hypotheses are based on experimental data suggesting two independent molecules as candidates for the primary steps of L - R determination: a dynein-like motor protein may transport a chiral determinant to one side of the cell, establishing a distinction between the right and the left sides. This cell asymmetry may then be used to establish broad cell fields of differential gene expression by a gap junction protein with asymmetric activity.
-
(1997)
Med Hyp
-
-
Levin, M.1
Nascone, N.2
-
5
-
-
0029089617
-
A molecular pathway determining left - right asymmetry in chick embryogenesis
-
Levin M, Johnson RL, Stern CD, Kuehn M, Tabin C. A molecular pathway determining left - right asymmetry in chick embryogenesis. Cell. 82:1995;803-814.
-
(1995)
Cell
, vol.82
, pp. 803-814
-
-
Levin, M.1
Johnson, R.L.2
Stern, C.D.3
Kuehn, M.4
Tabin, C.5
-
6
-
-
0025153882
-
Activin can reduce the formation of axial structures and is expressed in the hypoblast of the chick
-
Mitrani E, Ziv T, Thomsen G, Shimoni Y, Melton DA, Bril A. Activin can reduce the formation of axial structures and is expressed in the hypoblast of the chick. Cell. 63:1990;495-501.
-
(1990)
Cell
, vol.63
, pp. 495-501
-
-
Mitrani, E.1
Ziv, T.2
Thomsen, G.3
Shimoni, Y.4
Melton, D.A.5
Bril, A.6
-
7
-
-
0028886965
-
Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo
-
Stern CD, Yu RT, Kakizuka A, Kintner CR, Matthews LS, Vale WW, Evans RM, Umesono K. Activin and its receptors during gastrulation and the later phases of mesoderm development in the chick embryo. Dev Biol. 172:1995;192-205.
-
(1995)
Dev Biol
, vol.172
, pp. 192-205
-
-
Stern, C.D.1
Yu, R.T.2
Kakizuka, A.3
Kintner, C.R.4
Matthews, L.S.5
Vale, W.W.6
Evans, R.M.7
Umesono, K.8
-
8
-
-
0027760995
-
Sonic hedgehog mediates the polarizing activity of the ZPA
-
Riddle RD, Johnson RL, Laufer E, Tabin C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell. 75:1993;1401-1416.
-
(1993)
Cell
, vol.75
, pp. 1401-1416
-
-
Riddle, R.D.1
Johnson, R.L.2
Laufer, E.3
Tabin, C.4
-
9
-
-
0031051863
-
Control of vertebrate left-right asymmetry by a Snail-related zinc finger gene
-
of outstanding interest. This paper reports the identification of a new molecular component of the L - R handedness pathway in chick that appears to participate in regulating heart looping. The chick Snail-related gene (cSnr) is expressed on the right side of the lateral plate mesoderm, opposite to the nodal expression domain. Onset and persistence of expression is slightly delayed temporally with respect to nodal. Alteration of cSnR using antisense oligonucleotides is associated with randomization of the direction of heart looping. cSnR is most likely downstream of nodal.
-
Isaac A, Sargent MG, Cooke J. Control of vertebrate left-right asymmetry by a Snail-related zinc finger gene. of outstanding interest Science. 275:1997;1301-1304 This paper reports the identification of a new molecular component of the L - R handedness pathway in chick that appears to participate in regulating heart looping. The chick Snail-related gene (cSnr) is expressed on the right side of the lateral plate mesoderm, opposite to the nodal expression domain. Onset and persistence of expression is slightly delayed temporally with respect to nodal. Alteration of cSnR using antisense oligonucleotides is associated with randomization of the direction of heart looping. cSnR is most likely downstream of nodal.
-
(1997)
Science
, vol.275
, pp. 1301-1304
-
-
Isaac, A.1
Sargent, M.G.2
Cooke, J.3
-
10
-
-
0028180752
-
A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
-
Conlon FL, Lyons KM, Takaesu N, Barth KS, Kispert A, Herrmann B, Robertson EJ. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development. 120:1994;1919-1928.
-
(1994)
Development
, vol.120
, pp. 1919-1928
-
-
Conlon, F.L.1
Lyons, K.M.2
Takaesu, N.3
Barth, K.S.4
Kispert, A.5
Herrmann, B.6
Robertson, E.J.7
-
11
-
-
0029993646
-
Relationship between asymmetric nodal expression and the direction of embryonic turning
-
of outstanding interest. This paper describes genes involved in the pathway determining the L - R body axis in the developing mouse embryo. Nodal is expressed asymmetrically on the left side of the node and in the lateral plate mesoderm at early somite stages. Its expression pattern is perturbed in invlinv mutant embryos in which body situs is reversed, indicating a strong correlation between the sidedness of nodal expression and the direction of heart looping and axial rotation. Experiments uncover a genetic interaction between nodal and the transcription factor HNF3β as embryos heterozygous for both genes show marked alterations of the nodal expression domain that are associated with ambiguities in embryonic body situs in later development.
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Collignon J, Varlet I, Robertson EJ. Relationship between asymmetric nodal expression and the direction of embryonic turning. of outstanding interest Nature. 381:1996;155-158 This paper describes genes involved in the pathway determining the L - R body axis in the developing mouse embryo. Nodal is expressed asymmetrically on the left side of the node and in the lateral plate mesoderm at early somite stages. Its expression pattern is perturbed in invlinv mutant embryos in which body situs is reversed, indicating a strong correlation between the sidedness of nodal expression and the direction of heart looping and axial rotation. Experiments uncover a genetic interaction between nodal and the transcription factor HNF3β as embryos heterozygous for both genes show marked alterations of the nodal expression domain that are associated with ambiguities in embryonic body situs in later development.
-
(1996)
Nature
, vol.381
, pp. 155-158
-
-
Collignon, J.1
Varlet, I.2
Robertson, E.J.3
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12
-
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0029913091
-
Conserved left - right asymmetry of nodal expression and alterations in murine situs inversus
-
of outstanding interest. Expression of the TGF-β genes nodal and Xnr-1, examined in mouse and Xenopus embryos respectively, are shown to be left sided. nodal expression is altered in the two mouse mutant strains, iv and inv, characterized by randomization or inversion of body situs, suggesting that nodal acts downstream of these mutations.
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Lowe LA, Supp DM, Sampath K, Yokoyama T, Wright CVE, Potter SS, Overbeek P, Kuehn MR. Conserved left - right asymmetry of nodal expression and alterations in murine situs inversus. of outstanding interest Nature. 381:1996;158-161 Expression of the TGF-β genes nodal and Xnr-1, examined in mouse and Xenopus embryos respectively, are shown to be left sided. nodal expression is altered in the two mouse mutant strains, iv and inv, characterized by randomization or inversion of body situs, suggesting that nodal acts downstream of these mutations.
-
(1996)
Nature
, vol.381
, pp. 158-161
-
-
Lowe, L.A.1
Supp, D.M.2
Sampath, K.3
Yokoyama, T.4
Wright, C.V.E.5
Potter, S.S.6
Overbeek, P.7
Kuehn, M.R.8
-
13
-
-
0028787260
-
Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation
-
Jones CM, Kuehn MR, Hogan BLM, Smith JC, Wright CVE. Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development. 121:1995;3651-3662.
-
(1995)
Development
, vol.121
, pp. 3651-3662
-
-
Jones, C.M.1
Kuehn, M.R.2
Hogan, B.L.M.3
Smith, J.C.4
Wright, C.V.E.5
-
14
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0029417162
-
A novel TGF-β-like gene, fugacin, specifically expressed in the Spemann organizer of Xenopus
-
Ecochard V, Cayrol C, Foulquier F, Zaraisky A, Duprat A-M. A novel TGF-β-like gene, fugacin, specifically expressed in the Spemann organizer of Xenopus. Dev Biol. 172:1995;699-703.
-
(1995)
Dev Biol
, vol.172
, pp. 699-703
-
-
Ecochard, V.1
Cayrol, C.2
Foulquier, F.3
Zaraisky, A.4
Duprat, A.-M.5
-
15
-
-
0029049830
-
A nodal-related gene defines a physical and functional domain within the Spemann organizer
-
Smith WC, McKendry R, Ribisi S Jr, Harland RM. A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell. 82:1995;37-46.
-
(1995)
Cell
, vol.82
, pp. 37-46
-
-
Smith, W.C.1
McKendry, R.2
Ribisi S., Jr.3
Harland, R.M.4
-
16
-
-
0029809261
-
A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation
-
Lustig KD, Kroll K, Sun E, Ramos R, Elmendorf H, Kirschner MW. A Xenopus nodal-related gene that acts in synergy with noggin to induce complete secondary axis and notochord formation. Development. 122:1996;3275-3282.
-
(1996)
Development
, vol.122
, pp. 3275-3282
-
-
Lustig, K.D.1
Kroll, K.2
Sun, E.3
Ramos, R.4
Elmendorf, H.5
Kirschner, M.W.6
-
17
-
-
0031569878
-
Xnr4: A Xenopus nodal-related gene expressed in the Spemann organizer
-
Joseph EM, Melton DA. Xnr4: a Xenopus nodal-related gene expressed in the Spemann organizer. Dev Biol. 183:1997;367-372.
-
(1997)
Dev Biol
, vol.183
, pp. 367-372
-
-
Joseph, E.M.1
Melton, D.A.2
-
18
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0029932564
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Left - right asymmetric expression of the TGF-β family member lefty in mouse embryos
-
of outstanding interest. A new member of the TGF-β family has been identified in mouse that is involved in the establishment of L - R handedness. Lefty is expressed transiently on the left side of the prospective floor plate and the lateral mesoderm with a timing similar to that described for nodal, prior to the first morphological sign of asymmetry in the embryo ([11,12). Asymmetric expression of lefty is altered in the two situs inversus mouse mutants, iv and inv.
-
Meno C, Saijoh Y, Fujii H, Ikeda M, Yokoyama T, Yokoyama M, Toyoda Y, Hamada H. Left - right asymmetric expression of the TGF-β family member lefty in mouse embryos. of outstanding interest Nature. 381:1996;151-155 A new member of the TGF-β family has been identified in mouse that is involved in the establishment of L - R handedness. Lefty is expressed transiently on the left side of the prospective floor plate and the lateral mesoderm with a timing similar to that described for nodal, prior to the first morphological sign of asymmetry in the embryo ([11,12). Asymmetric expression of lefty is altered in the two situs inversus mouse mutants, iv and inv.
-
(1996)
Nature
, vol.381
, pp. 151-155
-
-
Meno, C.1
Saijoh, Y.2
Fujii, H.3
Ikeda, M.4
Yokoyama, T.5
Yokoyama, M.6
Toyoda, Y.7
Hamada, H.8
-
19
-
-
0030932236
-
Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
-
Varlet I, Collignon J, Robertson EJ. Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development. 124:1997;1033-1044.
-
(1997)
Development
, vol.124
, pp. 1033-1044
-
-
Varlet, I.1
Collignon, J.2
Robertson, E.J.3
-
20
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature. 383:1996;407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
Young, K.E.4
Corden, J.L.5
Westphal, H.6
Beachy, P.A.7
-
21
-
-
0028176755
-
Activin/inhibin β B subunit gene disruption leads to defects in eyelid development and female reproduction
-
Vassalli A, Matzuk MM, Gardner HA, Lee KF, Jaenisch R. Activin/inhibin β B subunit gene disruption leads to defects in eyelid development and female reproduction. Genes Dev. 8:1994;414-427.
-
(1994)
Genes Dev
, vol.8
, pp. 414-427
-
-
Vassalli, A.1
Matzuk, M.M.2
Gardner, H.A.3
Lee, K.F.4
Jaenisch, R.5
-
22
-
-
0028929864
-
Different phenotypes for mice deficient in either activins or activin receptor type II
-
Matzuk MM, Kumar TR, Bradley A. Different phenotypes for mice deficient in either activins or activin receptor type II. Nature. 374:1995;356-360.
-
(1995)
Nature
, vol.374
, pp. 356-360
-
-
Matzuk, M.M.1
Kumar, T.R.2
Bradley, A.3
-
23
-
-
0028929863
-
Functional analysis of activins during mammalian development
-
Matzuk MM, Kumar TR, Vassalli A, Bickenbach JR, Roop DR, Jaenisch R, Bradley A. Functional analysis of activins during mammalian development. Nature. 374:1995;354-356.
-
(1995)
Nature
, vol.374
, pp. 354-356
-
-
Matzuk, M.M.1
Kumar, T.R.2
Vassalli, A.3
Bickenbach, J.R.4
Roop, D.R.5
Jaenisch, R.6
Bradley, A.7
-
24
-
-
0030022980
-
Left - right asymmetric localization of flectin in the extracellular matrix during heart looping
-
of outstanding interest. An extracellular matrix protein named Flectin is shown to be expressed asymmetrically on the left side of the heart-forming region of the developing chick embryo. This molecule seems to be regulated by RA and is expressed on the reverse side of the body in embryos showing spontaneous inversion in the heart looping, implying a functional relationship with cardiac looping.
-
Tsuda T, Philp N, Zile MH, Linask KK. Left - right asymmetric localization of flectin in the extracellular matrix during heart looping. of outstanding interest Dev Biol. 173:1996;39-50 An extracellular matrix protein named Flectin is shown to be expressed asymmetrically on the left side of the heart-forming region of the developing chick embryo. This molecule seems to be regulated by RA and is expressed on the reverse side of the body in embryos showing spontaneous inversion in the heart looping, implying a functional relationship with cardiac looping.
-
(1996)
Dev Biol
, vol.173
, pp. 39-50
-
-
Tsuda, T.1
Philp, N.2
Zile, M.H.3
Linask, K.K.4
-
25
-
-
0031081234
-
Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry
-
of special interest. Two extracellular matrix proteins expressed asymmetrically in precardiac fields and which appear to be linked with subsequent heart looping in the chick embryo have been identified. hLAMP-1 expression predominates on the left side of the precardiac populations, whereas JB3, a fibrillin-associated protein, is expressed more strongly within the right precardiac region at stage 5. Moreover, their sided expression is altered by retinoic acid treatment and correlates with a randomization in the direction of heart looping.
-
Smith SM, Dickman ED, Thompson RP, Sinning AR, Wunsch AM, Markwald RR. Retinoic acid directs cardiac laterality and the expression of early markers of precardiac asymmetry. of special interest Dev Biol. 182:1997;162-171 Two extracellular matrix proteins expressed asymmetrically in precardiac fields and which appear to be linked with subsequent heart looping in the chick embryo have been identified. hLAMP-1 expression predominates on the left side of the precardiac populations, whereas JB3, a fibrillin-associated protein, is expressed more strongly within the right precardiac region at stage 5. Moreover, their sided expression is altered by retinoic acid treatment and correlates with a randomization in the direction of heart looping.
-
(1997)
Dev Biol
, vol.182
, pp. 162-171
-
-
Smith, S.M.1
Dickman, E.D.2
Thompson, R.P.3
Sinning, A.R.4
Wunsch, A.M.5
Markwald, R.R.6
-
26
-
-
0029549692
-
A subclass of bHLH proteins required for cardiac morphogenesis
-
Srivastava D, Cserjesi P, Olson EN. A subclass of bHLH proteins required for cardiac morphogenesis. Science. 270:1995;1995-1999.
-
(1995)
Science
, vol.270
, pp. 1995-1999
-
-
Srivastava, D.1
Cserjesi, P.2
Olson, E.N.3
-
27
-
-
0028205003
-
Induction of a second neural axis by the mouse node
-
Beddington RSP. Induction of a second neural axis by the mouse node. Development. 120:1994;613-620.
-
(1994)
Development
, vol.120
, pp. 613-620
-
-
Beddington, R.S.P.1
-
28
-
-
0027985756
-
Morphogenesis of the murine node and notochordal plate
-
Sulik K, Dehart DB, Inagaki T, Vrablic JL, Gesteland K, Schoenwolf GC. Morphogenesis of the murine node and notochordal plate. Dev Dyn. 201:1994;260-278.
-
(1994)
Dev Dyn
, vol.201
, pp. 260-278
-
-
Sulik, K.1
Dehart, D.B.2
Inagaki, T.3
Vrablic, J.L.4
Gesteland, K.5
Schoenwolf, G.C.6
-
31
-
-
0026563136
-
Mesoderm movement and fate during avian gastrulation and neurulation
-
Schoenwolf GC, Garcia-Martinez V, Dias MS. Mesoderm movement and fate during avian gastrulation and neurulation. Dev Dyn. 193:1992;235-248.
-
(1992)
Dev Dyn
, vol.193
, pp. 235-248
-
-
Schoenwolf, G.C.1
Garcia-Martinez, V.2
Dias, M.S.3
-
32
-
-
0028905285
-
Vertebrate embryo handedness
-
Cooke J. Vertebrate embryo handedness. Nature. 374:1995;681.
-
(1995)
Nature
, vol.374
, pp. 681
-
-
Cooke, J.1
-
34
-
-
0030578449
-
Role of notochord in specification of cardiac left - right orientation in zebrafish and Xenopus
-
of outstanding interest. This paper shows that L - R cardiac orientation is dependent on dorso-anterior structures including notochord and is specified during neurulation stages in Xenopus laevis. Zebrafish no tail and floating head mutants with defective notochord development also have randomized cardiac L - R asymmetry
-
Danos MC, Yost HU. Role of notochord in specification of cardiac left - right orientation in zebrafish and Xenopus. of outstanding interest Dev Biol. 177:1996;96-103 This paper shows that L - R cardiac orientation is dependent on dorso-anterior structures including notochord and is specified during neurulation stages in Xenopus laevis. Zebrafish no tail and floating head mutants with defective notochord development also have randomized cardiac L - R asymmetry.
-
(1996)
Dev Biol
, vol.177
, pp. 96-103
-
-
Danos, M.C.1
Yost, H.U.2
-
35
-
-
0029854744
-
Initiation of vertebrate left - right axis formation by maternal Vg1
-
of special interest. Injection of BVg1 RNA into the right-hand side of the Nieuwkoop centre in Xenopus randomizes cardiac and visceral L - R asymmetry and alters Xnr-1 expression. The authors propose that endogenous Vg1, a maternal gene, is differentially regulated on the left and right sides of blastula and is part of the molecular pathway for L - R development.
-
Hyatt BA, Lohr JL, Yost HJ. Initiation of vertebrate left - right axis formation by maternal Vg1. of special interest Nature. 384:1996;62-65 Injection of BVg1 RNA into the right-hand side of the Nieuwkoop centre in Xenopus randomizes cardiac and visceral L - R asymmetry and alters Xnr-1 expression. The authors propose that endogenous Vg1, a maternal gene, is differentially regulated on the left and right sides of blastula and is part of the molecular pathway for L - R development.
-
(1996)
Nature
, vol.384
, pp. 62-65
-
-
Hyatt, B.A.1
Lohr, J.L.2
Yost, H.J.3
-
36
-
-
0031238780
-
Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo
-
of special interest
-
Levin M, Pagan S, Roberts DJ, Cooke J, Kuehn MR, Tabin C. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. of special interest Dev Biol. 1997; Extending previous results [5] on lateral asymmetry in chick embryos, this study shows a correlation between asymmetrically expressed genes, activin βB, Shh and nodal, and both heart looping and embryonic axial rotation. Moreover, manipulations that perturb cardiac orientation independently alter body situs.
-
(1997)
Dev Biol
-
-
Levin, M.1
Pagan, S.2
Roberts, D.J.3
Cooke, J.4
Kuehn, M.R.5
Tabin, C.6
-
37
-
-
77957211015
-
Visceral inversion and associated anomalies in the mouse
-
Hummel KP, Chapman DB. Visceral inversion and associated anomalies in the mouse. J Hered. 50:1959;9-23.
-
(1959)
J Hered
, vol.50
, pp. 9-23
-
-
Hummel, K.P.1
Chapman, D.B.2
-
38
-
-
0017050268
-
Random determination of a developmental process
-
Layton WMJ. Random determination of a developmental process. J Hered. 67:1976;336-338.
-
(1976)
J Hered
, vol.67
, pp. 336-338
-
-
Layton, W.M.J.1
-
39
-
-
0027158027
-
Reversal of left - right asymmetry: A situs inversus mutation
-
Yokoyama T, Copeland NG, Jenkins NA, Montgomery CA, Elder FF, Overbeek PA. Reversal of left - right asymmetry: a situs inversus mutation. Science. 260:1993;679-682.
-
(1993)
Science
, vol.260
, pp. 679-682
-
-
Yokoyama, T.1
Copeland, N.G.2
Jenkins, N.A.3
Montgomery, C.A.4
Elder, F.F.5
Overbeek, P.A.6
-
40
-
-
0030907502
-
Left - right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development
-
of outstanding interest. This paper shows that Xnr-1 expression is altered by treatments that disrupt dorso-anterior development and that are known to perturb normal L - R development in Xenopus. In addition, cultured explants of lateral plate mesoderm derived from both sides of the body express Xnr-1, suggesting that Xnr-1 expression may normally be repressed on the right side by dorso-anterior midline cells.
-
Lohr JL, Danos MC, Yost HJ. Left - right asymmetry of a nodal-related gene is regulated by dorsoanterior midline structures during Xenopus development. of outstanding interest Development. 124:1997;1465-1472 This paper shows that Xnr-1 expression is altered by treatments that disrupt dorso-anterior development and that are known to perturb normal L - R development in Xenopus. In addition, cultured explants of lateral plate mesoderm derived from both sides of the body express Xnr-1, suggesting that Xnr-1 expression may normally be repressed on the right side by dorso-anterior midline cells.
-
(1997)
Development
, vol.124
, pp. 1465-1472
-
-
Lohr, J.L.1
Danos, M.C.2
Yost, H.J.3
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