Influence of indoles(melatonin, serotonin and tryptophan) on the porphyrin metabolism in vitro

Skin Pharmacology and Physiology

Volumn 10, Issue 4, 1997, Pages 221-224

  Kalka, K ^a   Fritsch, C ^a   Bolsen, K ^a   Verwohlt, B ^a   Goerz, G ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Melatonin; Porphyrin metabolism; Serotonin; Tryptophan; aminolevulinic acid

Indexed keywords

AMINOLEVULINIC ACID; MELATONIN; PORPHYRIN; SEROTONIN; TRYPTOPHAN;

ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CULTURE MEDIUM; HUMAN; HUMAN CELL; PORPHYRIN METABOLISM; PRIORITY JOURNAL;

5-AMINOLEVULINATE SYNTHETASE; ANIMALS; CELL LINE; FEMALE; HUMANS; KERATINOCYTES; LIVER; MELATONIN; PORPHYRINS; RATS; RATS, WISTAR; SEROTONIN; SKIN; TRYPTOPHAN;

EID: 0030779192     PISSN: 16605527     EISSN: 16605535     Source Type: Journal    
DOI: 10.1159/000211507     Document Type: Article

References (16)

1. Arcndt J: Melatonin and the Mammalian Pineal Gland, London, Chapman & Hall, 1995.
2. Reinberg A, Smolensky M: Biological Rhythms in Medicine, New York, Springer, 1983.
3. Touitou Y, Arendt J, Pevet P: Melatonin and the pineal gland: From basic science to clinical application, Amsterdam, Exccrpta Medica, 1993.
4. Nebert DW: Proposed role of drug-metabolizing enzymes: Regulation of steady-state levels of the ligands that effect growth, homeostasis, differentiation and neuroendocrine functions, Mol Endocrinol 1991;5: 1203-1214.
5. Nebert DW: Drug-metabolizing enzymes in ligand-modulated transcription, Biochem Pharmacol 1994; 47:25-37.
6. Tosini G, Menaker M: Circadian rhythms in cultured mammalian retina, Science 1996:272:419-421.
7. Itoh MT, Hattori A, Nomura T, Sumi Y, Suzuki T: Melatonin and arylalkylamine-N- acetyltransferase activity in the silkworm, Bombyx mori, Mol Cell Endocrirnol 1995; 115:59-64.
8. Leone RM, Silman RE: Melatonin can be differentially metabolized in the rat to produce N-acetylseroto-nin in addition to 6-hydroxymelato-nin, Endocrinology 1984; 114:1825-1831.
9. Olesce J, Wesche A: The Harderian gland (mini review), Comp Biochem Physiol 1989;93A:655-665.
10. Menendez-Pelacz A, Rodriguez C, Dominguez P: 5-Aminolevulinatc synthase mRNA levels in the harderian gland of Syrian hamsters: Correlation with porphyrin concentrations and regulation by androgens and melatonin, Mol Cell Endocrinol 1991;80:177-182.
11. Rodriguez C, Kotler M, Menendez-Pclaez A, Antolin I, Uria H, Reiter RJ: Circadian rhythm in 5-amino-laevulinate synthase mRNA levels in the harderian gland of the Syrian hamster: Involvement of light-dark cycle and pineal function, Endocrine 1994:2:863-868.
12. Puy H, Deybach JC, Baudry P, Cal-lebert J, Touitou Y, Nordmann Y: Decreased nocturnal plasma melatonin levels in patients with recurrent acute intermittent porphyria attacks, Life Sci 1993;53:621-627.
13. Piomelli S, Young P, Gay G: Anti-cromethod for free erythrocyte porphyrins: The FEP test, J Lab Clin Med 1973;81:932-940.
14. Lowry OH, Roscbrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent, J Biol Chem 1951;193:265-275.
15. Marver HS, Tschudy DP, Perlroth MG, Collins A: 8-Aminolaevulinic acid synthetase, J Biol Chem 1966; 241:2803-2809.
16. Rannug U, Agurell E, Rannug A, Cederberg H: Certain tryptophan photoproducts arc inhibitors of cytochrome Pjso-depcndcnt mutagenicity, Environ Mol Mutagen 1992; 20:289-292.