Effects of extracts of Tanacetum species on human polymorphonuclear leucocyte activity in vitro

Phytotherapy Research

Volumn 11, Issue 7, 1997, Pages 479-484

  Brown, A M G ^a   Edwards, C M ^a   Davey, M R ^a   Power, J B ^a   Lowe, K C ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Fractionation; Parthenolide; PMNL chemiluminescence; Tanacetum

Indexed keywords

PARTHENOLIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; TANACETUM EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE ACTIVATION; NEUTROPHIL; NORMAL HUMAN;

EID: 0030778754     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199711)11:7<479::AID-PTR129>3.0.CO;2-W     Document Type: Article

References (25)

1. Abad, M. J., Bermejo, P., and Villar, A. (1995). An approach to the genus Tanacetum L. (Compositae): Phytochemical and pharmacological review. Phytother. Res. 9, 79-92.
2. Abad, M. J., Bermejo, P., Valverde, S., and Villar, A. (1994). Anti-inflammatory activity of hydroxyachillin, a sesquiterpene lactone from Tanacetum microphyllum. Planta Med. 60, 228-231.
3. Abad, M. J., Bermejo, P., Villar, A., and Valverde, S. (1993). Anti-inflammatory activity of two flavonoids from Tanacetum microphyllum. J. Nat. Prod. 56, 1164-1167.
4. Barsby, R. W. J., Knight, D. W., and McFadzean, I. (1993a). A chloroform extract of the herb feverfew blocks voltage-dependent potassium currents recorded from single smooth muscle cells. J. Pharm. Pharmacol. 45, 641-645.
5. Barsby, R. W. J., Salan, U., Knight, D. W., and Hoult, J. R. S. (1993b). Feverfew and vascular smooth muscle: extracts from fresh and dried plants show opposing pharmacological profiles, dependent upon sesquiterpene lactone content. Planta Med. 59, 20-25.
6. Bramwell, D., and Bramwell, Z. I. (1974). Wild Flowers of the Canary Islands, pp. 24. Stanley Thornes (Publishers) Ltd., London.
7. Bremer, K. (1994). Asteraceae: Cladistics and Classification. Timber Press Inc., Cambridge.
8. Bremer, K., and Humphries, C. J. (1993). Generic monograph of the Asteraceae-Anthemideae. Bull. Nat. Hist. Mus. Lond. (Bot.) 23, 71-177.
9. Brown, A. M. G., Edwards, C. M., Power, J. B., Davey, M. R., and Lowe, K. C. (1997). Pharmacological activity of feverfew [Tanacetum parthenium (L.) Schultz-Bip.]: Assessment by inhibition of human polymorphonuclear leucocyte chemiluminescence in vitro. J. Pharm. Pharmacol. 49, 558-561.
10. Brown, A. M. G., Lowe, K. C., Davey, M. R., and Power, J. B. (1996a). Feverfew (Tanacetum parthenium L.). Tissue culture and parthenolide synthesis. Plant Sci. 116, 223-232.
11. Brown, A. M. G., Lowe, K. C., Davey, M. R., Power, J. B., Knight, D. W., and Heptinstall, S. (1996b). Comparison of extraction procedures for parthenolide in feverfew (Tanacetum parthenium). Phytochem. Anal. 7, 86-91.
12. Gershenzon, J., and Croteau, R. (1991). Terpenoids. In, Herbivores: Their Interactions with Secondary Plant Metabolites. Volume 1: The Chemical Participants, 2nd edn, ed. by G. A. Rosenthal and M. R. Berenbaum, pp. 165-219. Academic Press, Inc, London.
13. González, A. G., Barrera, J. B., Méndez, J. T., Sánchez, M. L., and Martínez, J. L. E. (1992). Sesquiterpene lactones and other constituents of Tanacetum species. Phytochemistry 31, 1821-1822.
14. Groenewegen, W. A., and Heptinstall, S. (1990). A comparison of the effects of feverfew and parthenolide, a component of feverfew, on human platelet activity in vitro. J. Pharm. Pharmacol. 42, 553-557.
15. Groenewegen, W. A., Knight, D. W., and Heptinstall, S. (1986). Compounds extracted from feverfew that have anti-secretory activity contain an α-methylene butyrotactone unit. J. Pharm. Pharmacol. 38, 709-712.
16. Harborne, J. B., Heywood, V. H., and Saleh, N. A. M. (1970). Chemosystematics of the Compositae: Flavonoid patterns in the Chrysanthemum complex of the tribe Anthemideae. Phytochemistry 9, 2011-2017.
17. Hayes, N. A., and Foreman, J. C. (1987). The activity of compounds extracted from feverfew on histamine release from rat mast cells. J. Pharm. Pharmacol. 39, 466-470.
18. Heptinstall, S., Awang, D. V. C., Dawson, B. A., Kindack, D., Knight, D. W., and May, J. (1992). Parthenolide content and bioactivity of feverfew [Tanacetum parthenium (L.) Schultz-Bip.]. Estimation of commercial and authenticated feverfew products. J. Pharm. Pharmacol. 44, 391-395.
19. Heptinstall, S., White, A., Williamson, L., and Mitchell, J. R. A. (1985). Extracts of feverfew inhibit granule secretion in blood platelets and polymorphonuclear leucocytes. Lancet 1071-1073.
20. Holopainen, M., Hiltunen, R., and von Schantz, M. (1987a). A study of tansy chemotypes. Planta Med. 53, 284-287.
21. Holopainen, M., Hiltunen, R., Lokki, J., Forsén, K., and von Schantz, M. (1987b). Model for the genetic control of thujone, sabinene and umbellone in tansy (Tanacetum vulgare L.). Hereditas 106, 205-208.
22. Loesche, W., Michel, E., Heptinstall, S., Krause, S., Groenewegen, W. A., Pescarmona, G. P., and Thielmann, K. (1988). Inhibition of the behaviour of human polynuclear leukocytes by an extract of Chrysanthemum parthenium. Planta Med. 54, 381-384.
23. Morel, F., Doussiere, J., and Vignais, P. V. (1991). The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects. Eur. J. Biochem. 201, 523-546.
24. Neilson, C. P., Crowley, J. J., Vestal, R. E., and Connolly, M. J. (1992). Impaired beta-adrenoreceptor function, increased leukocyte respiratory burst, and broncial hyper-responsiveness. J. Allergy Clin. Immunol. 90, 825-832.
25. Williams, C. A., Hoult, J. R. S., Harborne, J. B., Greenham, J., and Eagles, J. (1995). Biologically active lipophilic flavonol from Tanacetum parthenium. Phytochemistry 38, 267-270.