Identification of G protein-coupled receptors potently stimulating migration of human transitional-cell carcinoma cells

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 356, Issue 6, 1997, Pages 769-776

  Lümmen, Gerd ^a   Virchow, Sebastian ^a   Rümenapp, Ulrich ^a   Schmidt, Martina ^a   Wieland, Thomas ^a   Otto, Thomas ^a   Rübben, Herbert ^a   Jakobs, Karl H ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Bladder cancer cells; J82 cells; LPA; Migration; Thrombin

Indexed keywords

BOMBESIN; BRADYKININ; CYCLIC AMP; CYTOCHALASIN B; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTAMINE; PHOSPHOLIPASE C; THROMBIN;

ANIMAL CELL; ARTICLE; BLADDER CANCER; CALCIUM MOBILIZATION; CONTROLLED STUDY; CYTOSKELETON; METASTASIS POTENTIAL; NONHUMAN; SIGNAL TRANSDUCTION; TRANSITIONAL CELL CARCINOMA;

EID: 0030777695     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005117     Document Type: Article

References (37)

1. Ahmed S, Lee J, Kozma R, Best A, Monfries C, Lim L (1993) A novel functional target for tumor-promoting phorbol esters and lysophosphatidic acid. The p21rac-GTPase activating protein n-chimaerin. J Biol Chem 268:10709-10712
2. Berridge MJ, Downes CP, Hanley MR (1982) Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J 206:587-595
3. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgramm quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
4. Brown KD, Blakeley DM, Hamon MH, Laurie MS, Corps AN (1987) Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells. Biochem J 245:631-639
5. Della Bianca V, Grzeskowiak M, Cassatella MA, Zeni L, Rossi F (1986) Phorbol 12,myristate 13,acetate potentiates the respiratory burst while inhibits phosphoinositide hydrolysis and calcium mobilization by formyl-methionyl-leucyl-phenylalanine in human neutrophils. Biochem Biophys Res Commun 135: 556-565
6. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
7. Hall A (1994) Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu Rev Cell Biol 10:31-54
8. Hepler JR, Earp HS, Harden TK (1988) Long-term phorbol ester treatment down-regulates protein kinase C and sensitizes the phosphoinositide signaling pathway to hormone and growth factor stimulation. Evidence for a role of protein kinase C in agonist-induced desensitization. J Biol Chem 263:7610-7619
9. Huttenlocher A, Sandborg RR, Horwitz AF (1995) Adhesion in cell migration. Curr Opinion Cell Biol 7:697-706
10. Imamura F, Horai T, Mukai M, Shinkai K, Sawada M, Akedo H (1993) Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D. Biochem Biophys Res Commun 193:497-503
11. Just I, Fritz G, Aktories K, Giry M, Popoff MR, Boquet P, Hegenbarth S, von Eichel-Streiber C (1994) Clostridium difficile toxin B acts on the GTP-binding protein Rho. J Biol Chem 269: 10706-10712
12. Just I, Selzer J, Wilm M, von Eichel-Streiber C, Mann M, Aktories K (1995) Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature 375:500-503
13. Kawabata S, Tsutsumi R, Kohara A, Yamaguchi T, Nakanishi S, Okada M (1996) Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors. Nature 383:89-92
14. 2+ fluctuations modulate the rate of neuronal migration. Neuron 17:275-285
15. Korn ED (1978) Biochemistry of actomyosin-dependent cell motility (a review). Proc Natl Acad Sci USA 75:588-599
16. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacterophage T4. Nature 227:680-685
17. Lauffenburger DA, Horwitz AF (1996) Cell migration: A physically integrated molecular process. Cell 84:359-369
18. Liotta LA, Starcke ML, Aznavoorian SA, Beckner ME, Schiffmann E (1991) Tumour cell motility. Semin Cancer Biol 2: 111-114
19. Moolenaar WH (1995) Lysophosphatidic acid signalling. Curr Opinion Cell Biol 7:203-210
20. 13 deficiency. Science 275:533-536
21. O'Toole C, Price ZH, Ohnuki Y, Unsgaard B (1978) Ultrastructure, karyology and immunology of a cell line originated from a human transitional-cell carcinoma. Br J Cancer 38:64-76
22. Otto T, Birchmeier W, Schmidt U, Hinke A, Schipper J, Rübben H, Raz A (1994) Inverse relation of E-cadherin and autocrine motility factor receptor expression as a prognostic factor in patients with bladder carcinomas. Cancer Res 54:3120-3123
23. Raghavan D, Shipley WU, Garnick MB, Russell PJ, Richie JP (1990) Biology and management of bladder cancer. N Engl J Med 322:1129-1138
24. Ruff M, Schiffmann E, Terranova V, Pert CB (1985) Neuropeptides are chemoattractants for human tumor cells and monocytes: A possible mechanism for metastasis. Clin Immunol Immunopathol 37:387-396
25. Schmidt M, Bienek C, van Koppen CJ, Michel MC, Jakobs KH (1995) Differential calcium signalling by m2 and m3 muscarinic acetylcholine receptors in a single cell type. NaunynSchmiedeberg's Arch Pharmacol 352:469-476
26. Schmidt M, Bienek C, Rümenapp U, Zhang C, Lümmen G, Jakobs KH, Just I, Aktories K, Moos M, von Eichel-Streiber C (1996) A role for Rho in receptor- and G protein-stimulated phospholipase C. Reduction in phosphatidylinositol 4,5-bisphosphate by Clostridium difficile toxin B. Naunyn-Schmiedeberg's Arch Pharmacol 354:87-94
27. Stasia M-J, Jouan A, Bourmeyster N, Boquet P, Vignais PV (1991) ADP-ribosylation of a small size GTP-binding protein in bovine neutrophils by the C3 exoenzyme of Clostridium botulinum and effect on the cell motility. Biochem Biophys Res Commun 180:615-622
28. Stoker M, Gherardi E (1991) Regulation of cell movement: the motogenic cytokines. Biochim Biophys Acta 1072:81-102
29. Stossel TP (1993) On the crawling of animal cells. Science 260: 1086-1094
30. Takai Y, Sasaki T, Tanaka K, Nakanishi H (1995) Rho as a regulator of the cytoskeleton. Trends Biochem Sci 20:227-231
31. Takaishi K, Kikuchi A, Kuroda S, Kotani K, Sasaki T, Takai Y (1993) Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility. Mol Cell Biol 13:72-79
32. Takaishi K, Sasaki T, Kato M, Yamochi W, Kuroda S, Nakamura T, Takeichi M, Takai Y (1994) Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility. Oncogene 9:273-279
33. 1 receptors. J Cell Biol 110: 1211-1215
34. Van Roy F, Vareel M (1992) Tumour invasion: effects of cell adhesion and motility. Trends Cell Biol 2:163-169
35. 1-adrenoceptor subtypes. Mol Pharmacol 50:17-22
36. 1 subunits to the cytoskeleton in myeloid differentiated human leukemia (HL-60) cells. Eur J Biochem 239:752-758
37. Zigmond SH (1996) Signal transduction and actin filament organization. Curr Opinion Cell Biol 8:66-73