Metastatic potential of human melanoma cells in nude mice - Characterisation of phenotype, cytokine secretion and tumour-associated antigens

British Journal of Cancer

Volumn 74, Issue 2, 1996, Pages 194-199

  Schadendorf, D ^a,d   Fichtner, I ^b   Makki, A ^a   Alijagic, S ^a   Kupper M ^c   Mrowietz, U ^c   Henz, B M ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Integrin expression; Interleukin 8; Liver metastases; Spontaneous metastasis; Xenograft model

Indexed keywords

CYTOKINE; INTERLEUKIN 8; TUMOR ANTIGEN; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; GENE TARGETING; GENE THERAPY; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; MALE; MELANOMA CELL; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUDE MOUSE; PHENOTYPE; PLEURA EFFUSION; PRIORITY JOURNAL; SKIN METASTASIS; TUMOR XENOGRAFT;

ANIMALS; ANTIGENS, NEOPLASM; BASE SEQUENCE; CELL ADHESION MOLECULES; CELL DIVISION; FEMALE; FLOW CYTOMETRY; HLA ANTIGENS; HUMANS; INTERLEUKIN-8; MALE; MELANOMA; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; PHENOTYPE; PIGMENTS, BIOLOGICAL; SKIN NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030035709     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.337     Document Type: Article

References (44)

1. AHMANN DL, CREAGAN ET, HAHN RG, EDMONSON JH, BISEL HF AND SCHAID DJ. (1989). Complete responses and long-term survivals after systemic chemotherapy for patients with advanced malignant melanoma. Cancer, 63, 224-227.
2. ARTUC M, NÜRNBERG W, CZARNETZKI BM AND SCHADENDORF D. (1995). Characterization of gene regulatory elements for selective gene expression in human melanoma cells. Biochem. Biophys. Res. Comm., 213, 699-705.
3. BŌHM M, MÖLLER P, KALBFLEISCH U, WORM M, CZARNETZKI BM AND SCHADENDORF D. (1994). Lysis of allogeneic and autologous melanoma cells by IL-7-induced lymphokine-activated killer cells. Br. J. Cancer, 70, 54-59.
4. BONFIL RD, VINYALS A, BUSTUOABAD OD, LLORENS A, BENAVIDES FJ, GONZALEZGARRIGUES M AND FABRA A. (1994). Stimulation of angiogenesis as an explanation of matrigel-enhanced tumorigenicity. Int. J. Cancer, 58, 233-239.
5. BOUCHARD B, DEL MARMOL V, JACKSON IJ, CHERIF D AND DUBERTRET L. (1994). Molecular characterization of a human tyrosinase-related-protein-2 cDNA. Patterns of expression in melanocytic cells. Eur. J. Biochem., 219, 127-134.
6. COULIE PG, BRICHARD V, VAN PEL A, WÖLFEL T, SCHNEIDER J, TRAVERSARI C, MATTEI S, DE PLAEN E, LURQUIN C, SZIKORA JP, RENAULD J-C AND BOON T. (1994). A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med., 180, 35-42.
7. 3 vibronectin- receptor expression in melanocytic tumour progression. Histopathology, 24, 249-256.
8. 5 are related to tumor progression in situ but not to metastatic capacity of cell lines in nude mice. Int. J. Cancer, 61, 491-496.
9. D'URSO, CM, WANG Z, CAO Y, TATAKE R, ZEFF RA AND FERRONE S. (1991). Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in β2m gene expression. J. Clin. Invest., 87, 284-292.
10. FIDLER IJ. (1986). Rationale and methods for the use of nude mice to study the biology and therapy of human metastasis. Cancer Metastasis Rev., 5, 29-49.
11. FODSTAD O, KJONNIKSEN I, AAMDAL S, NESLAND JM, BOYD MR AND PHIL A. (1988). Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-1 melanoma. Cancer Res., 48, 4382-4388.
12. GAUGLER B, VAN DEN EYNDE B, VAN DER BRUGGEN P, ROMERO P, GAFORIO JJ, DE PLAEN E, LETHE' B, BRASSEUR F AND BOON T. (1994). Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. J. Exp. Med., 179, 921-930.
13. HAMBY CV, LIAO S-K, KANAMARU T AND FERRONE S. (1987). Immunogenicity of human melanoma-associated antigens defined by murine monoclonal antibodies in allogeneic and xenogeneic hosts. Cancer Res., 47, 5284-5289.
14. HEARING VJ AND TSUKAMOTO K. (1991). Enzymatic control of pigmentation in mammals. FASEB J., 5, 2902-2909.
15. HERLYN M. (1990). Human melanoma: development and progression. Cancer Metastasis Rev., 9, 101-112.
16. HERLYN M, THURIN J, BALABAN G, BENNICELLI JL, HERLYN D, ELDER DE, BONDI E, GUERY D, NOWELL P, CLARK WH AND KOPROWSKI H. (1985). Characteristics of cultured human melanocytes isolated from different stages of tumor progression. Cancer Res., 45, 5670-5676.
17. HOFFMANN RM. (1994). Orthotopic is orthodox: why are orthotopic-transplant metastatic models different from all other models? J. Cell Biochem., 56, 1-3.
18. HOUGHTON AN. (1994). Cancer antigens: immune recognition of self and altered self. J. Exp. Med., 180, 1-4.
19. JUHASZ I, ALBELDA SM, ELDER DE, MURPHY GF, ADACHI K, HERLYN D, VALYI-NAGY IT AND HERLYN M. (1993). Growth and invasion of human melanomas in human skin grafted to immunodeficient mice. Am. J. Pathol., 143, 528-537.
20. KAWAKAMI Y, ELIYAHU S, SAKAGUCHI K, ROBBINS P, RIVOLTINI L, YANELLI JR, APELLA E AND ROSENBERG SA. (1994). Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J. Exp. Med., 180, 347-352.
21. KWON BS, CHINTAMANENI C, KOZAK CA, COPELAND NG, GILBERT DJ, JENKINS N, BARTON D, FRANCKE U, KOBAYASHI Y AND KIM KK. (1991). A melanocyte-specific gene, Pmel 17, maps near the silver coat color locus on mouse chromosome 10 and is in a syntenic region on human chromosome 12. Proc. Natl Acad. Sci. USA, 88, 9228-9232.
22. LIOTTA LA AND STETLER-STEVENSON WG. (1991). Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res., 51, 5054s-5059s.
23. LU C AND KERBEL RS. (1993). Interleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression. J. Cell Biol., 120, 1281-1288.
24. METHA RR, GRAVES JM, SHILKAITES A, HART GD AND GUPTA TKD. (1995). Breast carcinoma cell lines with metastatic potential in mice. Int. J. Oncol., 6, 731-736.
25. MILLER N AND VILE R. (1995). Targeted vectors for gene therapy. FASEB J., 9, 190-199.
26. 1 integrin receptor in the proliferative response to quiescent human melanoma cells to fibronectin. Cancer Res., 52, 4499-4506.
27. RAUTH S, KICHINA J, GREEN A, BRATESCU L AND DAS GUPTA TK. (1994). Establishment of a human melanoma cell line lacking p53 expression and spontaneously metastasizing in nude mice. Anticancer Res., 14, 2457-2464.
28. RODOLFO M, BALSARI A, CLEMENTE C, PARMIANI G AND FOSSATI G. (1988). Tumorigenicity and dissemination of primary and metastatic human melanomas implanted into different sites in athymic nude mice. Invasion Metastasis, 8, 317-331.
29. RUOSLATHI E. (1991). Integrins. J. Clin. Invest., 87, 1-5.
30. SCHADENDORF D, MÖLLER A, ALGERMISSEN B, WORM M, STICHERLING M AND CZARNETZKI BM. (1993a). Interleukin 8 (IL-8) produced by human melanoma cells in vitro is an essential autocrine growth factor. J. Immunol., 151, 2667-2675.
31. SCHADENDORF D, GAWLIK C, HANEY U, OSTMEIER H, SUTER L AND CZARNETZKI BM. (1993b). Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours. J. Pathol., 170, 429-434.
32. SHIBATA K, TAKEDA K, TOMITA Y, TAGAMI H AND SHIBAHARA S. (1992). Downstream region of the human tyrosinase-related protein gene enhances its promoter activity. Biochem. Biophys. Res. Comm., 184, 568-575.
33. SINGH RK, GUTMAN M, RADINSKY R, BUCANA CD AND FIDLER IJ. (1994). Expression of interleukin 8 correlates with metastatic potential of human melanoma cells in nude mice. Cancer Res., 54, 3242-3247.
34. SHOEMAKER RH, DYKES DJ, PLOWMAN J, HARRISON SD, GRISWOLD DP Jr, ABBOT BJ, MAYO JG, FOGSTAD O AND BOYD MR. (1991). Practical spontaneous metastasis model for in vivo therapeutic studies using a human melanoma. Cancer Res., 51, 2837-2841.
35. SMITH B, SELBY P, SOUTHGATE J, PITTMAN K, BRADLEY C AND BLAIR GE. (1991). Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction. Lancet, 338, 1227-1229.
36. STICHERLING M, SCHRÖDER J-M AND CHRISTOPHERS E. (1989). Production and characterization of monoclonal antibodies against the novel neutrophil activating peptide NAP/IL-8. J. Immunol., 143, 1628-1634.
37. TAGLIAN A AND HUANG P. (1995). The nude and SCID mice as a tumor model in experimental cancer biology. Cancer J., 8, 52-58.
38. VAN DER BRUGGEN P, TRAVERSARI C, CHOMEZ P, LURQUIN C, DE PLAEN E, VAN DEN EYNDE B, KNUTH A AND BOON T. (1991). A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science, 254, 1643-1647.
39. VAN MUIJEN GNP, JANSEN KFJ, CORNELISSEN IMHA, SMEETS DFCM, BECK JLM AND RUITER DJ. (1991). Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice. Int. J. Cancer, 48, 85-91.
40. VAN MUIJEN GNP, DANEN EHJ, VEERKAMP JH, RUITER DJ, LESLEY J AND DEN HEUVEL LPWJ. (1995). Glycoconjugate profile and CD44 expression in human melanoma cell lines with different metastatic capacity. Int. J. Cancer, 61, 241-248.
41. WAGNER SN, WAGNER C, HÖFLER H, ATKINSON MJ AND GOOS M. (1995). Expression cloning of the cDNA encoding a melanoma associated Ag recognized by mAb HMB-45. Lab. Invest., 73, 229-235.
42. WANG Z, CAO Y, ALBINO AP, ZEFF RA, HOUGHTON AN AND FERRONE S. (1993). Lack of HLA class I antigen expression by melanoma cells SK-Mel-33 caused by a reading frameshift in β2-microglobulin messenger RNA. J. Clin. Invest., 91, 684-692.
43. WELCH DR, BISI JE, MILLER BE, CONAWAY D, SEFTOR EA, YOHEN KH, GILMORE LB, SEFTOR REB, NAKAJIMA M AND HENDRIX MJC. (1991). Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line. Int. J. Cancer, 47, 227-237.
44. XIE, X, BRUNNER N, JENSEN G, ALBRECTSEN J, GOTTHARDSEN B AND RYGAARD J. (1992). Comparative studies between nude mice and SCID mice on the growth and metastatic behaviour of xenografted human tumors. Clin Exp. Metastasis, 10, 201-210.