Regulation of myosin phosphatase through phosphorylation of the myosin- binding subunit in platelet activation

Blood

Volumn 90, Issue 10, 1997, Pages 3936-3942

  Nakai, Keiji ^b   Suzuki, Yoshinori ^b   Kihira, Hisakazu ^b   Wada, Hideo ^b   Fujioka, Masanori ^b   Ito, Masaaki ^b   Nakano, Takeshi ^b   Kaibuchi, Kozo ^b   Shiku, Hiroshi ^b   Nishikawa, Masakatsu ^a  

^a MIE UNIVERSITY   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SMOOTH MUSCLE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

EID: 0030775882     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v90.10.3936     Document Type: Article

References (31)

1. Fox JEB, Phillips DR: Role of phosphorylation in mediating the association of myosin with the cytoskeletal structures of human platelets. J Biol Chem 257:4120, 1982
2. 2+-calmodulin-dependent phosphorylation and platelet secretion. Nature 287:863, 1980
3. Daniel JL, Molish IR, Rigmaiden M, Stewart G: Evidence for a role of myosin phosphorylation in the initiation of the platelet shape change response. J Biol Chem 259:9826, 1984
4. Sellers JR: Regulation of cytoplasmic and smooth muscle myosin. Curr Biol 3:98, 1991
5. Nishikawa M, Toyoda H, Saito M, Morita K, Tawara I, Deguchi K, Kuno T, Shima H, Nagao M, Shirakawa S: Calyculin A and okadaic acid inhibit human platelet aggregation by blocking protein phosphatases types 1 and 2A. Cell Signal 6:59, 1994
6. Toyoda H, Nakai K, Omay SB, Shima H, Nagao M, Shiku H, Nishikawa M: Differential association of protein ser/thr phosphatase types 1 and 2A with the cytoskeleton upon platelet activation. Thromb Haemostas 76:1053, 1996
7. Alessi D, MacDougall LK, Sola MM, Ikebe M, Cohen P: The control of protein phosphatase-1 by targetting subunits. Eur J Biochem 210:1023, 1992
8. Shirazi A, Iizuka K, Fadden P, Mosse C, Somlyo AP, Somlyo AV, Haystead TAJ: Purification and characterization of the mammalian myosin light chain phosphatase holoenzyme. J Biol Chem 269:31598, 1994
9. Shimizu H, Ito M, Miyahara M, Ichikawa K, Okubo S, Konishi T, Naka M, Tanaka T, Hirano K, Hartshorne DJ, Nakano T: Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase. J Biol Chem 269:30407, 1994
10. Kubota Y, Nomura M, Kamm KE, Mumby MC, Stull JT: GTPγS-dependent regulation of smooth muscle contractile elements. Am J Physiol 263 (Cell Physiol 32):C403, 1992
11. Somlyo AP, Somlyo AV: Signal transduction and regulation in smooth muscle. Nature 372:231, 1994
12. Trinkle-Mulcahy L, Ichikawa K, Hartshorne DJ, Siegman MJ, Butler TM: Thiophosphorylation of the 130-kDa subunit is associated with a decreased activity of myosin light chain phosphatase in α-Toxin-permeabilized smooth muscle. J Biol Chem 270:18191, 1995
13. Ichikawa K, Ito M, Hartshorne DJ: Phosphorylation of the large subunit of myosin phosphatase and inhibition of phosphatase activity. J Biol Chem 271:4733, 1996
14. Takai Y, Sasaki T, Tanaka K, Nakanishi H: Rho as a regulator of the cytoskeleton. Trends Biochem Sci 20:227, 1995
15. Noda M, Yasuda-Fukazawa C, Moriishi K, Kato T, Okubo T, Kurokawa K, Takuwa Y: Involvement of rho in GTPγS-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells. FEBS Lett 367:246, 1995
16. Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K: Rho-associated kinase, a novel serine/threonine kinase, as a putative target for the small GTP binding protein Rho. EMBO J 15:2208, 1996
17. Kimura K, Ito M, Amano M, Chihara K, Fukata Y, Nakafuku M, Yamamori B, Feng J, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K: Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 273:245, 1996
18. 3,-induced monocytic differentiation of HL-60 cells. Cancer Res 55:774, 1995
19. Amano M, Chihara K, Kimura K, Fukata Y, Nakamura N, Matsuura Y, Kaibuchi K: Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase. Science 275:1308, 1997
20. Pato MD, Kerc E: Purification and characterization of a smooth muscle myosin phosphatase from turkey gizzards. J Biol Chem 260:12359, 1985
21. 3-induced upregulation of calcineurin during leukemic HL-60 cell differentiation. Blood 87:2947, 1996
22. 3-induced monocytic differentiation of leukemic HL-60 cells. FEBS Lett 375:299, 1995
23. Narumiya S: The small GTPase Rho: Cellular functions and signal transduction. J Biochem 120:215, 1996
24. Nemoto Y, Namba T, Teru-uchi T, Ushikubi F, Morii N, Narumiya S: A rho gene product in human blood platelets. I. Identification of the platelet substrate for botulinum C3 ADP-ribosyltrans-ferase as rhoA protein. J Biol Chem 267:20916, 1992
25. Watanabe G, Saito Y, Madaule P, Ishizaki T, Fujisawa K, Morii N, Mukai H, Ono Y, Kaizuka A, Narumiya S: Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science 271:645, 1996
26. Amano M, Mukai H, Ono Y, Chihara K, Matsui T, Hamajima Y, Okawa K, Iwamatsu A, Kaibuchi K: Identification of a putative target for Rho as the serine-threonine kinase protein kinase N. Science 271:648, 1996
27. Leung T, Manser E, Tan L, Lim L: A novel serine/threonine kinase binding the ras-related RhoA GTPase which translocates the kinase to peripheral membrane. J Biol Chem 270:29051, 1995
28. Nishikawa M, Komada F, Morita K, Deguchi K, Shirakawa S: Inhibition of platelet aggregation by the cAMP-phosphodiesterase inhibitor, cilostamide, may not be associated with activation of cAMP-dependent protein kinase. Cell Signal 4:453, 1992
29. Nishikawa M, Hidaka H, Shirakawa S: Possible involvement of direct stimulation of protein kinase C by unsaturated fatty acids in platelet activation. Biochem Pharmacol 37:3079, 1988
30. Morii N, Teru-uchi T, Tominaga T, Kumagai N, Kozaki S, Ushikubi F, Narumiya S: A rho gene product in human blood platelets. II. Effects of the ADP-ribosylation by botulinum C3 ADP-ribosyltransferase on platelet aggregation. J Biol Chem 267:20921, 1992
31. Carroll RC, Gerrard JM: Phosphorylation of platelet actin-binding protein during platelet activation. Blood 59:466, 1982