Predictive value of electrophoretically detected lipoprotein(a) for coronary heart disease and cerebrovascular disease in a community-based cohort of 9936 men and women

Circulation

Volumn 96, Issue 5, 1997, Pages 1390-1397

  Nguyen, Tu T ^a   Ellefson, Ralph D ^a   Hodge, David O ^a   Bailey, Kent R ^a   Kottke, Thomas E ^a   Abu Lebdeh, Haitham S ^a  

^a MAYO CLINIC   (United States)

Author keywords

Cerebrovascular disorders; Coronary disease; Lipoproteins; Risk factors

Indexed keywords

CHOLESTEROL; LIPOPROTEIN A; TRIACYLGLYCEROL;

ADULT; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CORONARY ARTERY DISEASE; DIABETES MELLITUS; ELECTROPHORESIS; FEMALE; HUMAN; HYPERTENSION; IMMUNOASSAY; ISCHEMIC HEART DISEASE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RISK FACTOR; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0030774676     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.5.1390     Document Type: Article

References (62)

1. Scanu AM, Lawn RM, Berg K. Lipoprotein(a) and atherosclerosis. Ann Intern Med. 1991;115:209-218.
2. Wald NJ, Law M, Watt HC, Wu T, Bailey A, Johnson AM, Craig WY, Ledue TB, Haddorn JE. Apolipoproteins and ischemic heart disease: implications for screening. Lancet. 1994;343:75-79.
3. Rosengren A, Whilhelmsen L, Eriksson E, Risberg B, Wedel H. Lipoprotein(a) and coronary heart disease: a prospective control study in a general population sample of middle aged men. Br Med J. 1990;301:1248-1251.
4. Sigurdsson G, Baldursdottir A, Sigvaldason H, Agnarsson U, Thorgeirsson G, Sigfusson N. Predictive value of apolipoproteins in a prospective survey of coronary artery disease in men. Am J Cardiol. 1992;69:1251-1254.
5. Cremer P, Nagel D, Mann H, Labrot B, Muller-Berninger R, Thiery J, Seidel D. Ranking of Lp(a) as a cardiovascular risk factor: results from a 10-year prospective study. In: Woodford FP, Davignon J, Sniderman A, eds. Atherosclerosis X. Amsterdam, Netherlands: Elsevier Science BV; 1995:903-907.
6. Schaefer EJ, Lamon-Fava S, Jenner JL, McNamara JR, Ordovas JM, Davis CE, Abolafia JM, Lippel K, Levy RI. Lipoprotein(a) levels and risk of coronary heart disease in men: the Lipid Research Clinics Coronary Primary Prevention Trial. JAMA. 1995;271: 999-1003.
7. Assmann G, Schulte H, von Eckardstein A. Hypertriglyceridemia and elevated lipoprotein(a) are risk factors for major coronary events in middle-aged men. Am J Cardiol. 1996;77:1179-1184.
8. Jauhiainen M, Koskinen P, Ehnholm C, Frick MH, Manttari M, Manninen V, Huttunen JK. Lipoprotein(a) and coronary heart disease risk: a nested case-control study of the Helsinki Heart Study participants. Atherosclerosis. 1991;89:59-67.
9. Ridker PM, Hennekens CH, Stampfer MJ. A prospective study of lipoprotein(a) and the risk of myocardial infarction. JAMA. 1993; 270:2195-2199.
10. Alfthan G, Pekkanen J, Jauhiainen M, Pitkaniemi J, Karvonen M, Tuomilehto J, Salonen JT, Ehnholm C. Relation of serum homocysteine and lipoprotein(a) concentrations to atherosclerotic disease in a prospective Finnish population based study. Atherosclerosis. 1994;106:9-19.
11. Ridker PM, Stampfer MJ, Hennekens CH. Plasma concentration of lipoprotein(a) and the risk of future stroke. JAMA. 1995;273: 1269-1273.
12. Dahlen GH, Guyton JR, Attar M, Farmer JA, Kautz JA, Gotto AM Jr. Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography. Circulation. 1986;74:758-765.
13. Bostom AG, Gagnon DR, Cupples A, Wilson PW, Jenner JL, Ordovas JM, Schaefer EJ, Castelii WP. A prospective investigation of elevated lipoprotein(a) detected by electrophoresis and cardiovascular disease in women: the Framingham Heart Study. Circulation. 1994;90:1688-1695.
14. Bostom A, Cupples A, Jenner J, Ordovas J, Seman L, Schaefer E, Wilson PW, Castelli W. Elevated plasma lipoprotein(a) and coronary heart disease in men aged 55 and younger. JAMA. 1996;276: 544-548.
15. WHO Study Group on Diabetes Mellitus. Technical Report Series 727. Geneva, Switzerland: World Health Organization; 1985.
16. Kurland LT, Elveback LR, Nobrega FT. Population studies in Rochester and Olmsted County, Minnesota, 1900-1968. In: Kessler II, Levin ML, eds. The Community as an Epidemiologic Laboratory: A Casebook of Community Studies. Baltimore, Md: Johns Hopkins University Press; 1970:47-70.
17. Kurland LT, Molgaard CA. The patient record in epidemiology. Sci Am. 1981;245:54-63.
18. Ellefson RD, Elveback LR, Hodgson PA, Weidman WH. Cholesterol and triglycerides in serum lipoproteins of young persons in Rochester, Minnesota. Mayo Clin Proc. 1978;53:307-320.
19. 2 lipoprotein of high density in human blood. Mayo Clin Proc. 1971;46:328-332.
20. Genest JJR, Jenner JL, McNamara JR, Ordovas JM, Silberman SR, Wilson PW, Schaefer EJ. Prevalence of lipoprotein(a) excess in coronary artery disease. Am J Cardiol. 1991;67:1039-1045.
21. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457-481.
22. Peto R, Peto J. Asymptotically efficient rank invariant procedures (with discussion). J R Stat Soc A. 1972;135:185-207.
23. Cox DR. Regression models and life-tables (with discussion). J R Stat Soc B. 1972;34:187-220.
24. Kostner GM, Avogaro P, Cazzolato G, Marth E, Bittolo-Bon G, Qunici GB. Lipoprotein Lp(a) and the risk for myocardial infarction. Atherosclerosis. 1981;38:51-61.
25. Dahlen GH, Guyton JR, Attar M, Farmer JA, Kautz JA, Gotto AM. Association of lipoprotein Lp(a) plasma lipids and other lipoproteins with coronary artery disease documented by angiography. Circulation. 1986;74:758-765.
26. Bruckert E, Truffert J, De Gennes JL, Lagaared JP, Bernard C, Federspiel MC, Giral P, Dairou F. Does electrophoresis reliably screen for high serum lipoprotein Lp(a)? Clin Chim Acta. 1990;188: 71-78.
27. Schultz JS, Shreffler DC, Harvie NR. Genetic and antigenic studies and partial purification of a human serum lipoprotein carrying the Lp antigenic determinant. Proc Natl Acad Sci U S A. 1968;61: 963-970.
28. Harvie NR, Schultz JS. Studies of Lp-lipoprotein as a quantitative genetic trait. Proc Natl Acad Sci U S A. 1970;66:99-103.
29. Rider AK, Levy RI, Fredrickson DS. 'Sinking' pre-β lipoprotein and the Lp antigen. Circulation. 1970;42(suppl III):III-10. Abstract.
30. Dahlen G, Ericson C, Furberg C, Lindkvist L, Svardsudd K. Studies on an extra pre-beta lipoprotein fraction. Acta Med Scand Suppl. 1972;531:1-29.
31. Frick MH, Dahlen G, Furberg C, Ericson C, Wiljasalo M. Serum pre-beta-1 lipoprotein fraction in coronary atherosclerosis. Acta Med Scand. 1974;195:337-340.
32. Heiberg A, Berg K. On the relationship between Lp(a) lipoprotein, 'sinking pre-beta lipoprotein,' and inherited hyperbetalipoproteinemia. Clin Genet. 1974;5:144-156.
33. Dahlen G, Ramberg UB. Pre-beta-1 lipoprotein and early detection of risk factors for coronary heart disease. Acta Med Scand. 1974; 195:341-344.
34. Albers JJ, Hazzard WR. Immunochemical quantification of human plasma Lp(a) lipoprotein. Lipids. 1974;9:15-26.
35. Albers JJ, Cabana VG, Warnick GR, Hazzard WR. Lp(a) lipoprotein: relationship to sinking pre-beta lipoprotein, hyperlipoproteinemia, and apolipoprotein B. Metabolism. 1975;24:1047-1054.
36. Linden L, Kallberg M, Gustafson A, Dahlen G. Studies on an additional pre-beta lipoprotein, sinking prebeta, I: isolation and characterization. Scand J Clin Lab Invest. 1976;36:51-58.
37. Dahlen G, Frick MH, Berg K, Valle M, Wiljasalo M. Further studies of Lp(a) lipoprotein/pre-beta-1-lipoprotein in patients with coronary heart disease. Clin Genet. 1975;8:183-189.
38. Petek W, Kostner G, Knoetgen U. Immunochemical characterization of the 'pre-' band in lipoprotein electrophoresis. Clin Chim Acta. 1972;38:460-462.
39. Ballantyne D, Jubb JS, Morgan HG, Lawrie TD. Study of the pedigree of a patient with type 3 hyperlipoproteinemia and sinking pre-beta lipoprotein. J Clin Pathol. 1973;26:163-166.
40. Hewitt D, Milner J, Breckenridge C, Maguire G. Heritability of 'sinking' pre-beta lipoprotein level: a twin study. J Clin Pathol. 1977;11:224-226.
41. Breckenridge WC, Maguire GF. Quantification of sinking pre-beta lipoprotein in human plasma. Clin Biochem. 1981;14:82-86.
42. Hewitt D, Milner J, Owen AR, Breckenridge WC, Maguire GF, Jones GJ, Little JA. The inheritance of sinking pre-beta lipoprotein and its relation to the Lp(a) antigen. Clin Genet. 1982;21:301-308.
43. Rhoads GG, Morton NE, Gulbrandsen CL, Kagan A. Sinking pre-beta lipoprotein and coronary heart disease in Japanese-American men in Hawaii. Am J Epidemiol. 1978;108:350-356.
44. Morton NE, Gulbrandsen CL, Rhoads GG, Kagan A. The Lp lipoprotein in Japanese. Clin Genet. 1978;14:207-212.
45. Avogaro G, Cazzolato G. 'Sinking' lipoprotein in normal, hyperlipoproteinemic, and atherosclerotic patients. Clin Chim Acta. 1975; 61:239-246.
46. Pagnan A, Kostner G, Braggion M, Ziron L. Relationship between 'sinking pre-beta lipoprotein' [Lp(a) lipoprotein] and age in a family kindred. Gerontology. 1982;28:381-385.
47. Pagnan A, Kostner G, Braggion M, Ziron L, Bittolo-Bon G, Avogaro P. Familial study on 'sinking pre-beta,' the Lp(a) lipoprotein and its relationship with serum lipids, apolipoprotein A-1 and B and clinical atherosclerosis. J Clin Chem Clin Biochem. 1983;21:267-272.
48. Gambert P, Lallement C, Padieu P. Cholesterol gas-liquid chromatographic microassay in serum lipoproteins separated by polyacrylamide gel electrophoresis. Clin Chim Acta. 1980;100:99-105.
49. Walden CE, Wahl PW, Kopp RH, Warnick GR, Oglivie JT, Hazzard WR, Hoover JJ, Albers JJ. Hyperlipidemia in the Pacific Northwest Bell Telephone Company Health Survey, part 1. Arteriosclerosis. 1983;3:117-124.
50. Kawakami K, Tsukada A, Okubo M, Tsukada T, Kobayashi Y, Yamaeda N, Murasa T. A rapid electrophoretic method for the detection of serum Lp(a) lipoprotein. Clin Chim Acta. 1989;185: 147-156.
51. McNamara JR, Campos H, Adolphson JL, Ordovas JM, Wilson PW, Albers JJ, Usher DC, Schaefer EJ. Screening for lipoprotein(a) elevations in plasma and assessment of size heterogeneity using gradient gel electrophoresis. J Lipid Res. 1989;30:747-755.
52. Pearson TA, Kwiterovich PO. Sinking pre-beta lipoprotein. Circulation. 1989;80(suppl II):II-102. Abstract.
53. Alvarez JJ, Lasuncion MA, Olmos JM, Herrera E. Interindividual variation in the partition of lipoprotein(a) into lipoprotein subfractions. Clin Biochem. 1993;26:399-408.
54. Nauck M, Winkler K, Wittmann C, Mayer H, Luley C, Marz W, Wieland W. Direct determination of lipoprotein(a) cholesterol by ultracentrifugation and agarose gel electrophoresis with enzymatic staining for cholesterol. Clin Chem. 1995;41:731-738.
55. Berg K, Dahlen G, Frick MH. Lp(a) lipoprotein in patients with coronary heart disease. Clin Genet. 1974;6:230-235.
56. Guyton JR, Dahlen GH, Patsch W, Kautz JA, Gotto AM Jr. Relationship of plasma lipoprotein Lp(a) levels to race and apolipoprotein B. Arteriosclerosis. 1985;5:265-272.
57. Brown SA, Morrisett JD, Boerwinkle E, Hutchinson R, Patsch W. The relation of lipoprotein(a) concentrations and apolipoprotein(a) phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk In Communities (ARIC) Study. Arterioscler Thromb. 1993;13:1558-1566.
58. Kottke BA, Bren ND. A particle concentration fluorescence immunoassay for Lp(a). In: Gotto AM Jr, Morrisett JD, eds. Chemistry and Physics of Lipids. Shannon, Ireland: Elsevier Science, Ireland Ltd; 1994;67/68:249-256.
59. Schaefer EJ, Jenner JL, Seman LJ, McNamara JR, Contois JH, Genest JJ, Wilson PW, Ordovas JM. Lp(a) and coronary heart disease. In: Woodford FP, Davignon J, Sniderman A, eds. Atherosclerosis X. Amsterdam, Netherlands: Elsevier Science BV; 1995: 79-82.
60. Ridker PM, Hennekens CH. Lipoprotein(a) and risks of cardiovascular disease. Ann Epidemiol. 1994;4:360-362.
61. Berg K. Lp(a) lipoprotein: an important genetic risk factor for atherosclerosis. In: Lusis AJ, Rotter JI, Sparkes RS, eds. Molecular Genetics of Coronary Artery Disease: Candidate Genes and Process in Atherosclerosis. Basel, Switzerland: Karger; 1992;14:189-207. Monographs in Human Genetics.
62. Vernon SM, Sarembock IJ, Ayers CR, Powers ER, Gimple LW. Lipoprotein(a) assayed from frozen serum degrades with time in storage. J Am Coll Cardiol. 1995;76A:917-992.