P-Glycoprotein-independent decrease in drug accumulation by phorbol ester treatment of tumor cells

Biochemical Pharmacology

Volumn 54, Issue 7, 1997, Pages 791-799

  Wielinga, Peter R ^a   Heijn, Marc ^a   Broxterman, Henk J ^a   Lankelma, Jan ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Drug transport; Multidrug resistance; P glycoprotein; Phorbol ester; Protein phosphorylation

Indexed keywords

CALCEIN ACETOXYMETHYL ESTER; DAUNORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; PHORBOL ESTER; PROTEIN KINASE C; STAUROSPORINE; UNCLASSIFIED DRUG; VERAPAMIL;

ARTICLE; CELL PH; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG TRANSPORT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR CELL;

ANTINEOPLASTIC AGENTS; DAUNORUBICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; ETOPOSIDE; FLUORESCEINS; HUMANS; HYDROGEN-ION CONCENTRATION; KB CELLS; P-GLYCOPROTEIN; PROTEIN KINASE C; TETRADECANOYLPHORBOL ACETATE;

EID: 0030774488     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00247-5     Document Type: Article

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