Deletion of the S component inverted repeat sequence c' and the nonessential genes U(S)1 through U(S)5 from the herpes simplex virus type 1 genome substantially impairs productive viral infection in cell culture and pathogenesis in the rat central nervous system

Journal of NeuroVirology

Volumn 3, Issue 4, 1997, Pages 247-264

  Rasty, Siyamak ^a,c   Poliani, P Luigi ^a,b   Fink, David J ^a   Glorioso, Joseph C ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c Genovo Inc   (United States)

Author keywords

Central nervous system; Gene transfer vector; HSV pathogenesis

Indexed keywords

REPETITIVE DNA; VIRUS DNA; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CENTRAL NERVOUS SYSTEM INFECTION; GENE DELETION; GENE TRANSFER; HERPES SIMPLEX VIRUS 1; HIPPOCAMPUS; INOCULATION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; VERO CELL; VIRUS ATTENUATION; VIRUS GENOME; VIRUS REPLICATION;

ANIMALIA; DNA VIRUSES; HERPES; HUMAN HERPESVIRUS 1; RODENTIA;

EID: 0030773904     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289709029466     Document Type: Article

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