Protective immunity against HSV-2 in the mouse vagina

Journal of Reproductive Immunology

Volumn 36, Issue 1-2, 1997, Pages 77-92

  Parr, Margaret B ^a   Parr, Earl L ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Herpes simplex virus; Immunoglobulin G (IgG); Mucosal immunity; Secretory immunoglobulin A (S IgA); T cell immunity; Vagina

Indexed keywords

VIRUS VACCINE;

ARTICLE; CELLULAR IMMUNITY; FEMALE; FEMALE GENITAL TRACT INFECTION; HERPES SIMPLEX VIRUS 2; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PRIORITY JOURNAL; VAGINA; VIRUS IMMUNITY;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; MICE; PROGESTERONE; T-LYMPHOCYTES; VAGINA;

EID: 0030772304     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0378(97)00055-7     Document Type: Article

References (72)

1. Allardyce R., Rademaker M. Female genital tract immunity and infertility after oral vaccination with sperm antigens in mice. Adv. Exp. Med. Biol. 216B:1987;1807-1813.
2. Baker D.A., Plotkin S.A. Enhancement of vaginal infection in mice by herpes simplex virus type II with progesterone. Proc. Soc. Exp. Biol. Med. 158:1978;131-134.
3. Baker M.B., Larson C.L., Ushijima R.N., Anderson F.D. Resistance of female mice to vaginal infection induced by herpesvirus hominis type 2: effects of immunization with Mycobacterium bovis, intravenous injection of specific herpesvirus hominis type 2 antiserum and a combination of these procedures. Infect. Immun. 10:1974;1230-1234.
4. Bourne N., Milligan G.N., Schleiss M.R., Berstein D.I., Stanberry L.R. DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2. Vaccine. 14:1996;1230-1234.
5. Briese V., Pohl W.-D., Noack K., Tischner H., Waldman R.H. Influenza specific antibodies in the female genital tract of mice after oral administration of live influenza vaccine. Arch. Gynecol. 240:1987;153-157.
6. Burns J.W., Siadat-Pajouh M., Krishnaney A.A., Breenberg H.B. Protective effect of rotavirus VP6-specific IgA monoclonal antibodies that lack neutralizing activity. Science. 272:1996;104-107.
7. Corbeil L.B. Vaccination strategies against Tritrichomanas foetus. Parasitol. Today. 10:1994;103-106.
8. Corey L., Spear P.G. Infections with herpes simplex viruses. Part 1. New Engl. J. Med. 314:1986;686-691.
9. Corey L., Spear P.G. Infections with herpes simplex viruses. Part 2. New Engl. J. Med. 314:1986;749-757.
10. Curtiss, R., Tinge, S.A., 1993. Recombinant avirulent salmonella vaccines and prospects for an antifertility vaccine. In: Griffin, P.D., Johnson, P.M. (Eds.), Local Immunity in Reproductive Tract Tissues. Oxford University Press, Oxford, pp. 459-476.
11. Di Tommaso A., Saletti G., Pizza M., Rappuoli R., Dougan G., Alrignani S., Douce G., DeMagistris M. Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant. Infect. Immun. 64:1996;974-979.
12. Drew M.D., Estradacorrea A., Underdown B.J., McDermott M.R. Vaccination by cholera toxin conjugated to a herpes simplex virus type 2 glycoprotein D-peptide. J. Gen. Virol. 73:1992;2357-2366.
13. Drew, M.D., Rosenthal, K.L., McDermott, M.R., 1993. The design of vaccines for inducing secretory immunity in the reproductive tract. In: Griffin, P.D., Johnson, P.M. (Eds.), Local Immunity in Reproductive Tract Tissues. Oxford University Press, Oxford, pp. 483-514.
14. Eis-Hubinger A.M., Schmidt D.S., Schneweis K.E. Anti-glycoprotein B monoclonal antibody protects T cell depleted mice against herpes simplex virus infection by inhibition of virus replication at the inoculated mucous membrane. J. Gen. Virol. 74:1993;379-385.
15. Estrada A., McDermott M.R., Underdown B.J., Snider D.P. Intestinal immunization of mice with antigen conjugated to anti-MHC class II antibodies. Vaccine. 13:1995;901-907.
16. Gallichan W.S., Rosenthal K.L. Specific secretory immune responses in the female genital tract following intranasal immunization with a recombinant adenovirus expressing glycoprotein B of herpes simplex virus. Vaccine. 13:1995;1589-1595.
17. Gallichan W.S., Rosenthal K.L. Effects of the estrous cycle on local humoral immune responses and protection of intranasally immunized female mice against herpes simplex virus type 2 infection in the genital tract. Virology. 224:1996;487-497.
18. Gallichan W.S., Rosenthal K.L. Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization. J. Exp. Med. 184:1996;1879-1890.
19. Greenblatt R.M., Lukehart S.A., Plummer F.A.et al. Genital ulceration as a risk factor for human immunodeficiency virus infection. AIDS. 2:1988;47-50.
20. Hazama M., Mayumiaono A., Miyazaki T., Hinuma S., Fujisawa Y. Intranasal immunization against herpes simplex virus infection by using a recombinant glycoprotein-D fused with immunomodulating proteins, the B-subunit of Escherichia-coli heat-labile enterotoxin and interleukin-2. Immunology. 78:1993;643-649.
21. Heritage P.L., Loomes L.M., Jianxiong J., Brook M.A., Underdown B.J., McDermott M.R. Novel polymer-grafted starch microparticles for mucosal delivery of vaccines. Immunology. 88:1996;162-168.
22. Holmgren J. Mucosal immunity and vaccination. FEMS Microbiol. Immunol. 89:1991;1-9.
23. Holmgren J., Clemens J., Sack D.A., Sanchez J., Svennerholm A.M. Oral immunization against cholera. Curr. Top. Microbiol. Immunol. 146:1989;197-204.
24. Kilian M., Mestecky J., Russell M.W. Defense mechanisms involving Fc-dependent functions of immunoglobulin A and their subversion by bacterial immunoblobulin A proteases. Microbiol. Rev. 52:1988;296-303.
25. Killian, M., Russell, M.W., 1994. Function of mucosal immunoglobulins. In: Ogra, P.L., Lamm, M.E., McGhee, J.R., Mestecky, J., Strober, W., Bienenstock, J. (Eds.), Handbook of Mucosal Immunology. Academic Press, San Diego, CA, pp. 127-137.
26. Kraehenbuhl J.P., Neutra M.R. Molecular and cellular basis of immune protection of mucosal surfaces. Physiol. Rev. 72:1992;853-879.
27. Kuklin N., Daheshia M., Karem K., Manickan E., Rouse B.T. Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization. J. Virol. 71:1997;3138-3145.
28. Lehner T., Wang Y.F., Cranage M., Bergmeier L.A., Mitchell E., Tao L., Hall G., Dennis M., Cook N., Brookes R., Klavinskis L., Doyle C., Ward R. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat. Med. 2:1996;767-775.
29. Liew F.Y., Russell S.M., Appleyard G., Brand C.M., Beale J. Cross protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity. Eur. J. Immunol. 14:1984;350-356.
30. Magnusson K., Stjernstrom I. Mucosal barrier mechanisms: interplay between secretory IgA (S-IgA), IgG and mucins on the surface properties and association of salmonellae with intestine and granulocytes. Immunology. 45:1982;239-248.
31. Markowitz, A., Lehner, A.M., 1978. Virus infections of the vagina. In: Hafez, E.S.E., Evans, T.N. (Eds.), The Human Vagina. Elsevier/North Holland Biomedical Press, pp. 451-467.
32. Marx P.A., Spira A.I., Gettie A., Dailey P.J., Veazey R.S., Lackner A.A., Mahoney C.J., Miller C.J., Claypool L.E., Ho D.D., Alexander N.J. Progesterone implants enhance SIV vaginal transmission and early virus load. Nat. Med. 2:1996;1084-1089.
33. Mazanec M.B., Coudret C.L., Fletcher D.R. Intracellular neutralization of influenza virus by immunoglobulin A anti-hemagglutinin monoclonal antibodies. J. Virol. 69:1995;1339-1343.
34. McDermott M.R., Smiley B.J., Brais P.L.J., Rudzroga H., Bienenstock J. Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2. J. Virol. 51:1984;247-253.
35. McDermott M.R., Brais L.J., Goettsche G.C., Evelegh M.J., Goldsmith C.H. Expression of immunity to intravaginal herpes simplex virus type 2 infection in the genital tract and associated lymph nodes. Arch. Virol. 93:1987;51-68.
36. McDermott M.R., Brais L.J., Evelegh M.J. Mucosal and systemic antiviral antibodies in mice inoculated intravaginally with herpes simplex virus type 2. J. Gen. Virol. 71:1990;1497-1504.
37. McGhee J.R., Mestecky J. In defense of mucosal surfaces: development of novel vaccines for IgA responses protective at the portals of entry of microbial pathogens. Infect. Dis. Clin. North. Am. 4:1990;315-341.
38. Mestecky J., Kutteh W.H., Jackson S. Mucosal immunity in the female genital tract: relevance to vaccination efforts against the human immunodeficiency virus. AIDS Res. Hum. Retroviruses. 10:1994;S11-S20.
39. Miller C.J., McChesney M.B., Lu X. Mucosal immune responses to SIV infection. Semin. Virol. 7:1996;139-145.
40. Milligan G.N., Bernstein D.I. Analysis of herpes simplex virus-specific T cells in the murine female genital tract following genital infection with herpes simples virus type 2. Virology. 212:1995;481-489.
41. Milligan G.N., Bernstein D.I. Generation of humoral immune responses against herpes simplex virus type 2 in the murine female genital tract. Virology. 206:1995;234-241.
42. Milligan G.N., Bernstein D.I. Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract. Virology. 229:1997;259-268.
43. Mogens, K., Russell, M.W., 1994. Function of mucosal immunoglobulins. In: Ogra, P.L., Lamm, M.E., McGhee, J.R., Mestecky, J., Strober, W., Bienenstock, J. (Eds.), Handbook of Mucosal Immunology. Academic Press, San Diego, CA, pp. 127-137.
44. Murdin A.D., Su H., Klein M.H., Caldwell H.D. Poliovirus hybrids expressing neutralization epitopes from variable domains I and IV of the major outer membrane protein of Chlamydia trachomatis elicit broadly cross-reactive C. trachomatis-neutralizing antibodies. Infect. Immun. 63:1995;1116-1121.
45. Murphy, B.R., 1994. Mucosal immunity to viruses. In: Ogra, P.L., Lamm, M.E., McGhee, J.R., Mestecky, J., Strober, W., Bienenstock, J. (Eds.), Handbook of Mucosal Immunology. Academic Press, San Diego, CA, pp. 333-343.
46. Muster T., Ferko B., Klima A., Purtscher M., Trkola A., Schulz P., Grassauer A., Engelhard O.G., Garcia-Sastre A., Palese P., Katinger H. Mucosal model of immunization against human immunodeficiency virus type 1 with a chimeric influenza virus. J. Virol. 69:1995;6678-6686.
47. Nahmias A.J., Lee F.K., Bechman-Nahmias S. Sero-epidemiological and -sociological patterns of herpes simplex virus infection in the world. Scand. J. Infect. Dis. Suppl. 69:1990;19-36.
48. O'Hagan D., Palin K., Davis S., Artursson P., Sjoholm I. Microparticles as potentially orally active immunological adjuvants. Vaccine. 7:1989;421-424.
49. Oggioni M.R., Manganelli R., Pozzi G. Immunization of mice by oral colonization with live recombinant commensal streptococci. Vaccine. 13:1995;775-779.
50. Ogra, P.L. (1996) Mucosal immunology: past, present and future. In: Vaccinia, Vaccination, Vaccinology: Jenner, Pasteur and Their Successors. Elsevier, Paris.
51. Overall J.D., Kern E.R., Schlitzer R.L., Friedman S.B., Glasgow L.A. Genital herpesvirus hominis infection in mice. I. Development of an experimental model. Infect. Immun. 11:1975;476-480.
52. Parr M.B., Parr E.L. Antigen recognition in the female reproductive tract: I. Uptake of intraluminal protein tracers in the mouse vagina. J. Reprod. Immunol. 17:1990;101-114.
53. Parr, M.B. and Parr, E.L., 1994. Mucosal immunity in the female and male reproductive tracts. In: Ogra, P.L., Lamm, M.E., McGhee, J.R., Mestecky, J., Strober, W., Bienenstock, J. (Eds.), Handbook of Mucosal Immunology. Academic Press, San Diego, CA, pp. 677-689.
54. Parr, M.B. and Parr, E.L., 1996. Immunoglobulins in the female genital tract. In: Bronson, R.A., Alexander, N.J., Anderson, D., Ware Branch, D., Kutteh, W.H. (Eds.), Reproductive Immunology. Blackwell Scientific, Cambridge, MA, pp. 275-308.
55. Parr M.B., Parr E.L. The role of T cells in immunity to HSV-2 infection in the mouse vagina. Immunol. Cell Biol. 75:1997;A10.
56. Parr, M.B., Parr, E.L., 1997b. Immunoglobulin G is the main protective antibody in mouse vaginal secretions after vaginal immunization with attenuated HSV-2. J. Virol. (in press).
57. Parr M.B., Kepple L., McDermott M.R., Drew M.D., Bozzola J.J., Parr E.L. A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2. Lab. Invest. 70:1994;369-380.
58. Parr E.L., Bozzola J.J., Parr M.B. Immunoglobulin concentrations in mouse vaginal mucus and immunity to HSV-2 infection. Clin. Immunol. Immunopathol. 76:1995;S57.
59. Quinnan G.V., Masur H., Rook A.H., Armstrong G., Frederick W.R., Epstein J., Manischewitz J.F., Macher A.M., Jackson L., Ames J., Smith H.A., Parker M., Pearson G.R., Parrillo J., Mitchell C., Straus S.E. Herpesvirus infections in the acquired immune deficiency syndrome. J. Am. Med. Assoc. 252:1984;72-77.
60. Sparling P.F., Elkins C., Wyrick P.B., Cohen M.S. Vaccines for bacterial sexually transmitted infections: a realistic goal. Proc. Soc. Exp. Biol. Med. 91:1994;2456-2456.
61. Srinivasan J., Tinge S., Wright R., Herr J.C., Curtiss III R. Oral immunization with attenuated Salmonella expressing human sperm antigen induces antibodies in serum and reproductive tract. Biol. Reprod. 53:1995;462-471.
62. Staats H.F., Jackson R.J., Marinaro M., Takahashi I., Kiyono H., McGhee J.R. Mucosal immunity to infection with implications for vaccine development. Curr. Opin. Immunol. 6:1994;572-583.
63. Staats H.F., Nichols W.G., Palker T.J. Mucosal immunity to HIV-1: systemic and vaginal antibody responses after intranasal immunization with the HIV-1 C4/V3 peptide T1SP10 MN(A). J. Immunol. 157:1996;462-472.
64. Stanberry L.R. Evaluation of herpes simplex virus vaccines in animals: the guinea pig vaginal model. Rev. Infect. Dis. 13:1991;S920-923.
65. Stanberry L.R., Kit S., Myers M.G. Thymidine kinase deficient herpes simplex virus type 2 infection in guinea pigs. J. Virol. 55:1985;322-328.
66. Starr S.E., Visintine A.M., Tomeh M.O., Nahmias A.J. Effects of immunostimulants on resistance of newborn mice to herpes simplex type 2 infection. Proc. Soc. Exp. Biol. Med. 152:1976;57-60.
67. Thapar M., Parr E.L., Parr M.B. Secretory immune responses in mouse vaginal fluid after pelvic, parenteral, or vaginal immunization. Immunology. 70:1990;121-125.
68. Tuffrey M., Taylor-Robinson D. Progesterone as a key factor in the development of a mouse model for genital tract infection with Chlamydia trachomatis. FEMS Microbiol. Lett. 12:1981;111-115.
69. Underdown B., Shiff J. Immunoglobulin A: strategic defense initiative at the mucosal surface. Annu. Rev. Immunol. 4:1986;389-417.
70. Ward M.E. The immunobiology and immunopathology of chlamydial infections. APMIS. 103:1995;769-796.
71. Whitley R., Arvin A., Prober C. Predictors of morbidity and mortality in neonates with herpes simplex virus infection. New Engl. J. Med. 154:1991;415-421.
72. Zhang X., Ya-Huan L., Koopman M., Doggett T., Tung K.S.K., Curtiss R. Antibody responses and infertility in mice following oral immunization with attenuated Salmonella typhimurium expressing recombinant murine ZP3. Biol. Reprod. 56:1997;33-41.