Cardiac compartment-specific overexpression of a modified retinoic acid receptor produces dilated cardiomyopathy and congestive heart failure in transgenic mice

Journal of Clinical Investigation

Volumn 100, Issue 8, 1997, Pages 1958-1968

  Colbert, Melissa C ^a   Hall, D Greg ^b   Kimball, Thomas R ^c   Witt, Sandra A ^c   Lorenz, John N ^d   Kirby, Margaret L ^e   Hewett, Timothy E ^a   Klevitsky, Raisa ^a   Robbins, Jeffrey ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Dilated cardiomyopathy; Heart failure; Left ventricular function; Retinoic acid receptors; Transgenic mice

Indexed keywords

ACTIN; ATRIAL NATRIURETIC FACTOR; RETINOIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN VENTRICLE DILATATION; CONGENITAL HEART MALFORMATION; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; HEART DEVELOPMENT; HEART DILATATION; HEART MUSCLE CONTRACTILITY; M MODE ECHOCARDIOGRAPHY; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENE;

EID: 0030772185     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119727     Document Type: Article

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