The discovery, characterization and crystallographically determined binding mode of an FMOC-containing inhibitor of HIV-1 protease

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 7, 1997, Pages 1311-1320

  Rutenber, Earl E ^a   De Voss, James J ^a   Hoffman, Lucas ^a   Stroud, Robert M ^a   Lee, Kwan H ^a   Alvarez, Juan ^a   McPhee, Fiona ^a   Craik, Charles ^a   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE DERIVATIVE; ENZYME INHIBITOR; PROTEINASE; PROTEINASE INHIBITOR;

ARTICLE; BINDING SITE; COMPUTER SIMULATION; CRYSTAL STRUCTURE; DATA BASE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME CONFORMATION; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; ARGININE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; FLUORENES; HALOPERIDOL; HIV PROTEASE; HIV PROTEASE INHIBITORS; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030769406     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00078-3     Document Type: Article

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