HIV-1-Tat modulates the function of monocytes and alters their interactions with microvessel endothelial cells: A mechanism of HIV pathogenesis

Journal of Immunology

Volumn 156, Issue 4, 1996, Pages 1638-1645

  Lafrenie, Robert M ^a   Wahl, Larry M ^a   Epstein, Jay S ^b   Hewlett, Indira K ^b   Yamada, Kenneth M ^a   Dhawan, Subhash ^b  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; METALLOPROTEINASE; TRANSACTIVATOR PROTEIN;

ANTIGEN EXPRESSION; ARTICLE; ENDOTHELIUM CELL; ENZYME RELEASE; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOMODULATION; IMMUNOPATHOGENESIS; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; LEUKOCYTE AGGREGATION; MONOCYTE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

EID: 0030059596     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Meltzer, M. S , D. R Skillman, P J Gomatos, D. C Kalter, and H. E. Gendelman. 1990. Role of mononuclear phagocytes in the pathogenesis of human immunodeficiency virus infection. Annu. Rev. Immunol 8:169
2. Griffin, G. E., K. Leung, T. M. Folks, S. Kunkel, and G. J Nabel. 1989. Activation of HIV sene expression during monocyte differentiation by induction of NF-κB Nature 339 218.
3. Koenig, S . H. E Gendelman, J M. Orenstein, M. C. Del Canto, G H. Peezeshkpour, M. Youngbluth, F Jannota, A. Aksamit, M. A. Martin, and A S. Fauci. 1986 Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233:1089.
4. White, D. A., and R. A. Matthay. 1989 Noninfectious pulmonary complications of infections with the human immunodeficiency virus. Am. Rev. Respir Dis. 140:1763
5. Dhawan, S., B. S. Weeks, C Soderland, H. W. Schnaper, L. A. Toro, S P. Asthana, I. K. Hewlett, W. G. Stetler-Stevenson, S. S. Yamada, K. M Yamada. and M. S. Meltzer 1995. HIV-1 infection alters monocyte interactions with human microvascular endothelial cells J. Immunol 154 422
6. Springer, T A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration the multistep paradigm. Cell 76:301.
7. Kuijpers, T. W . and J M Harlan. 1993. Monocyte-endothelial interactions insights and questions. J. Lab Clin Med. 122 641.
8. Beekhuizen, H . and R. van Furth 1993 Monocyte adherence to human vascular endothelium. J. Leukocyte Biol. 54:363
9. Vaishnav, Y. N., and F. Wong-Staal 1991 The biochemistry of AIDS Annu Rev. Biochem 60:577.
10. Ensoli, B., G. Barillari, S. Z. Salahuddin, R. C. Gallo, and F. Wong-Staal. 1990. Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature 345:84.
11. Green, M., and P. M. Loewenstein. 1988. Autonomous functional domains of chemically synthesized human immunodeficiency virus Tat transactivator protein. Cell 55:1179.
12. Brake, D. A., C. Debouck, and G. Biesecker. 1990. Identification of an Arg-Gly-Asp (RGD) cell adhesion site in human immunodeficiency virus type 1 transactivation protein, Tat J. Cell Biol. 111:1275
13. Roy, S., M G. Katze, N. T Parkin, I. Edery, A. G. Hovanessian, and N. Sonenberg 1990. Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product. Science 238:491.
14. Sharp, P. A., and R. A. Marciniak. 1990. HIV TAR: and RNA enhanced? Cell 59: 229
15. Green, W. C. 1991. The molecular biology of human immunodeficiency type 1 infection. New. Engl. J. Med. 324:308
16. Viscidi, R. P., K. Mayur, H. M Lederman, and A. D. Frankel. 1989. Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1. Science 246:1606.
17. Meyaard, L., S. A. Otto, R. R. Jonker, M J. Mijnster, R. P. M. Keet, and F. Miedema. 1992. Programmed death of T cells in HIV-1 infection. Science 257:217
18. Buonaguro, L., G Barillari, H. K. Chang, C A. Bohan, V. Kao, R. Morgan, R. C. Gallo, and B Ensoli. 1992 Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines. J Virol. 66:7159
19. Weeks, B. S., M. R Klotman, E Holloway, W. G Stetler-Stevenson, H. K. Kleinman, and P. E. Klotman. 1993. HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase. AIDS Res. Hum. Retroviruses 9:513.
20. Scala, G., M. R Ruocco, C Ambrosino, M. Mallardo, V. Giordano, F. Baldassarre, E. Dragonetti, I Quinto, and S. Venuta. 1994. The expression of the interleukin-6 gene is induced by the human immunodeficiency virus 1 Tat protein. J. Exp. Med. 179:961.
21. Westendorp, M O., V. A. Shatrov, K. Schulze-Osthoff, R. Frank, M Kraft, M. Los, P. H. Krammer, W. Droge, and V. Lehmann. 1994. HIV-1 Tat potentiates TNF-induced NF-kB activation and cytotoxicity by altering the cellular redox state. EMBO J. 14:546.
22. Gibellini, D., G. Zauli, M. C. Re, D. Milani, G. Furlini, E. Caramelli, S Capitani, and M. La Placa. 1994. Recombinant human immunodeficiency virus type-1 (HIV-1) Tat protein sequentially up-regulates IL-6 and TGF-beta-1 mRNA expression and protein synthesis in peripheral blood monocytes. Br. J. Haematol. 88 261.
23. Taylor, J P , C. Cupp, A. Diaz, M. Chowdhury, K. Khalili, S. A. Jimenez, and S Amini. 1992. Activation of expression of genes coding for extracellular matrix proteins in Tat-producing glioblastoma cells. Proc. Nad. Acad Sci USA 89:9617.
24. Howcroft, T. K., K Strebel, M. A. Martin, and D S. Singer. 1993. Repression of MHC class I gene promoter activity by two-exon Tat of HIV. Science 260:1320.
25. Purvis, S. F.. D. L. Georges, T. M. Williams, and M M. Lederman. 1992 Suppression of interleukin-2 and interleukin-2 receptor expression in Jurkat cells stably expressing the human immunodeficiency virus Tat protein. Cell Immunol 144.32.
26. Pocsik, E, M Higuchi, and B. B. Aggarwal. 1992. Down-modulation of cell surface expression of the p80 form of the tumor necrosis factor receptor by human immunodeficiency virus-1 tat gene. Lymphokine Cytokine Res. 11:317.
27. Herrmann, C. H., and A P Rice. 1993 Specific interaction of the human immunodeficiency virus Tat proteins with a cellular protein kinase Virology 197: 601.
28. Rhim, H , C. O. Echetebu, C. H Herrmann, and A. P Rice. 1994 Wild-type and mutant HIV-1 and HIV-2 Tat proteins expressed in Escherichia coli as fusions with glutathione S-transferase. J. Acquired Immune Defic. Syndr. 7:1116.
29. Wahl, L. M., I. M Katona, R L. Wilder, C. C. Winter, B. Haraoui, I. Scher, and S. M. Wahl. 1984. Isolation of human mononuclear cell subsets by counterflow centrifugal elutriation (CCE). Cell Immunol. 85:373
30. Liotta, L. A., and W. G. Stetler-Stevenson 1990 Metalloproteinases and cancer invasion. Semin. Cancer Biol 1:99
31. Birkedal-Hansen, H., and R. E. Taylor 1982. Detergent activation of latent collagenase and resolution of its component molecules. Biochem. Biophys. Res Commun 107:1173.
32. Chomczynski, P , and N. Sacchi 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162: 156.
33. Wilhelm, S. M., I E. Collier, B L. Marmer, A Z. Eisen, G. A. Grant, and G. I Goldberg. 1989. SV-40-transformed human lung fibroblasts secrete a 92 kDa type IV collagenase, which is identical to that secreted by normal human macrophages J. Biol. Chem. 264:17213.
34. Gutheil, W. G , M. Subramanyam, G. R. Flentke, D. G. Sanford, E. Munoz, B. T. Huber, and W. W Bachovchin. 1994 Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity Proc. Natl. Acad Sci USA 91:6594.
35. Barillari, G., R. Gendelman, R. C. Gallo, and B. Ensoli. 1993. The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD ammo acid sequence Proc. Natl. Acad. Sci. USA 90:7941.
36. 5 integrin to the basic domain of the HIV Tat protein and vitronectin. J. Cell Biol. 121:461.
37. Weeks, B. S., K Desai, P. M. Loewenstein, M. E. Klotman, P. E. Klotman, M. Green, and H. K. Kleinman. 1993. Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein. J. Biol. Chem. 268:5279.
38. Stein, H., R. Schwarting, and G. Niedobiek. 1989 Cluster report. CD26. In Leukocyte Typing IV. White Cell Differentiation Antigens W. Knapp, B. Dorken, W. R. Gilks, E P. Rieber, R. E. Schmidt, H. Stein, and A. E G Kr. von dem Borne, eds. Oxford University Press, London, p. 412
39. Krissansen, G. W., M. J. Elliot, C M. Lucas, F. C. Stomski, M. C. Berndt, D. A Cheresh, A. F. Lopez, and G. F. Burns. 1990. Identification of a novel integrin β subunit expressed on cultured monocytes (macrophages). J Biol Chem 265:823.
40. Busso, M, J. Thornthwaite, and L. Resnick. 1991. HIV-induced syncytium formation requires the formation of conjugates between virus-infected and uninfected T-cells in vitro. AIDS 5:1425.
41. Jonjic, N., P. Jilek, S Bernasconi, G. Peri, I. Martin-Padura, S. Cenzuales, E. Dejana, and A. Mantovani 1992. Molecules involved in the adhesion and cytotoxicity of activated monocytes on endothelial cells. J. Immunol. 148:2080.
42. Hober, D., A. Haque, P. Wattre, G. Beaucaire, Y. Mouton, and A. Capron. 1989. Production of tumor necrosis factor and interleukin-1 in patients with AIDS. Enhanced level of TNF is related to a higher cytotoxic activity. Clin Exp. Immunol. 78:329.
43. Albini, A., G Barillari, R. Benelli, R C. Gallo, and B. Ensoli. 1995. Angiogenic properties of human immunodeficiency virus type 1 Tat protein. Proc. Natl. Acad Sci. USA 92:4838.
44. Ward, P. A., and J. Varani. 1990. Mechanisms of neutrophil-mediated killing of endothelial cells J. Leukocyte Biol. 48:97.
45. Lafrenie, R. M., S. G. Shaughnessy, and F. W. Orr. 1992 Cancer cell interactions with injured or activated endothelium. Cancer Metastasis Rev. 11:377.
46. Westlin, W F , and M. A. Gimbrone, Jr 1993. Neutrophil-mediated damage to human vascular endothelium: role of cytokine activation Am. J Pathol. 142:117.
47. Pluznik, D. H , R Fridman and R. Reich. 1992 Correlation in the expression of type IV collagenase and the invasive and chemotactic abilities of myelomonocytic cells during differentiation into macrophages. Exp. Hematol. 20:57.
48. Bernhard, E. J , R J Muschel, and E. N. Hughs. 1990 Mr 92,000 gelatinase release correlates with the metastatic phenotype in transformed rat embryo cells. Cancer Res 50:3872.
49. Merril, J. E., and I. S. Chen. 1991 HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease. FASEB J. 5:2391.
50. Rosenberg, Z F , and A. S. Fauci. 1991. Immunopathogenesis of HIV infection. FASEB J. 5:2382.