Inhibition of mitosis and microtubule function through direct tubulin binding by a novel antiproliferative naphthopyran LY290181

Molecular Pharmacology

Volumn 52, Issue 3, 1997, Pages 437-444

  Wood, Dan L ^a   Panda, Dulal ^b   Wiernicki, Todd R ^a   Wilson, Leslie ^b   Jordan, Mary Ann ^b   Singh, Jai Pal ^a  

^a ELI LILLY AND COMPANY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 (3 PYRIDYL) 4H NAPHTHO[1,2 B]PYRAN 3 CARBONITRILE; 2 AMINO 4(3 PYRIDYL) (4H) NAPHTHO[1,2B]PYRAN 3 CARBONITRILE; 8 ANILINO 1 NAPHTHALENESULFONIC ACID; PYRAN DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DIABETIC ANGIOPATHY; DIABETIC RETINOPATHY; DRUG MECHANISM; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; HYPERTENSION; MICROTUBULE ASSEMBLY; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RESTENOSIS; SMOOTH MUSCLE FIBER;

EID: 0030768517     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.52.3.437     Document Type: Article

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