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Volumn 11, Issue 11, 1997, Pages 1608-1617

Analysis of the role of E2A-encoded proteins in insulin gene transcription

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; GLUCAGON; HELIX LOOP HELIX PROTEIN; INSULIN; OVALBUMIN; SOMATOSTATIN; TRANSCRIPTION FACTOR;

EID: 0030768351     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.11.0004     Document Type: Article
Times cited : (17)

References (49)
  • 1
    • 0027308886 scopus 로고
    • Factors regulating insulin gene transcription
    • Stein R 1993 Factors regulating insulin gene transcription. Trends Endocrinol Metab 4:96-100
    • (1993) Trends Endocrinol Metab , vol.4 , pp. 96-100
    • Stein, R.1
  • 2
    • 0026602931 scopus 로고
    • The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes
    • German MS, Moss LG, Wang, J, Rutter, WJ 1992 The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical β-cell nuclear complexes. Mol Cell Biol 12:1777-1788
    • (1992) Mol Cell Biol , vol.12 , pp. 1777-1788
    • German, M.S.1    Moss, L.G.2    Wang, J.3    Rutter, W.J.4
  • 3
    • 0028206319 scopus 로고
    • XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor
    • Peshavaria M, Gamer L, Henderson E, Teitelman G, Wright CVE, Stein R 1994 XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol 8:806-816
    • (1994) Mol Endocrinol , vol.8 , pp. 806-816
    • Peshavaria, M.1    Gamer, L.2    Henderson, E.3    Teitelman, G.4    Wright, C.V.E.5    Stein, R.6
  • 4
    • 0027944249 scopus 로고
    • Transcriptional regulation of the human insulin gene is dependent of the homeodomain proteins STF1/IPF1 acting through the CT boxes
    • Petersen HV, Serup P, Leonard J, Michelsen BK, Madsen OD 1994 Transcriptional regulation of the human insulin gene is dependent of the homeodomain proteins STF1/IPF1 acting through the CT boxes. Proc Natl Acad Sci USA 91:10465-10469
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10465-10469
    • Petersen, H.V.1    Serup, P.2    Leonard, J.3    Michelsen, B.K.4    Madsen, O.D.5
  • 5
    • 0025994835 scopus 로고
    • Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene
    • Shieh S-Y, Tsai M-J 1991 Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene. J Biol Chem 266:16708-16714
    • (1991) J Biol Chem , vol.266 , pp. 16708-16714
    • Shieh, S.-Y.1    Tsai, M.-J.2
  • 6
    • 0023477391 scopus 로고
    • A mutational analysis of the insulin gene transcription control region: Expression in beta cells is dependent on two related sequences within the enhancer
    • Karlsson O, Edlund T, Moss JB, Rutter, WJ, Walker MD 1987 A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer. Proc Natl Acad Sci USA 84:8819-8823
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 8819-8823
    • Karlsson, O.1    Edlund, T.2    Moss, J.B.3    Rutter, W.J.4    Walker, M.D.5
  • 7
    • 0024328366 scopus 로고
    • Pancreatic β-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative transcriptional elements
    • Whelan J, Poon D, Weil PA, Stein R 1989 Pancreatic β-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative transcriptional elements. Mol Cell Biol 9:3253-3259
    • (1989) Mol Cell Biol , vol.9 , pp. 3253-3259
    • Whelan, J.1    Poon, D.2    Weil, P.A.3    Stein, R.4
  • 8
    • 0024596435 scopus 로고
    • Mutagenesis of the rat insulin II 5′-flanking region defines sequences important for expression in HIT cells
    • Crowe DT, Tsai, M-J 1989 Mutagenesis of the rat insulin II 5′-flanking region defines sequences important for expression in HIT cells. Mol Cell Biol 9:1784-1789
    • (1989) Mol Cell Biol , vol.9 , pp. 1784-1789
    • Crowe, D.T.1    Tsai, M.-J.2
  • 10
    • 0027384997 scopus 로고
    • IPF-1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T 1993 IPF-1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12:4251-4259
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 11
    • 0028567837 scopus 로고
    • Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1
    • Peers B, Leonard J, Sharma S, Teitelman G, Montiminy MR 1995 Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF-1. Mol Endocrinol 8:1798-1806
    • (1995) Mol Endocrinol , vol.8 , pp. 1798-1806
    • Peers, B.1    Leonard, J.2    Sharma, S.3    Teitelman, G.4    Montiminy, M.R.5
  • 12
    • 0028869514 scopus 로고
    • Expression of murine STF-1, a putative insulin gene transcription factor, in β-cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny
    • Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CVE, Teitelman G 1995 Expression of murine STF-1, a putative insulin gene transcription factor, in β-cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121:11-18
    • (1995) Development , vol.121 , pp. 11-18
    • Guz, Y.1    Montminy, M.R.2    Stein, R.3    Leonard, J.4    Gamer, L.W.5    Wright, C.V.E.6    Teitelman, G.7
  • 13
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard J, Peers B, Johnson T, Ferrere K, Lee S, Montminy M 1993 Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 7:1275-1283
    • (1993) Mol Endocrinol , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferrere, K.4    Lee, S.5    Montminy, M.6
  • 14
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller CP, McGehee Jr RE, Habener JF 1994 IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13:1145-1156
    • (1994) EMBO J , vol.13 , pp. 1145-1156
    • Miller, C.P.1    McGehee Jr., R.E.2    Habener, J.F.3
  • 15
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H 1994 Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371:606-609
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 17
    • 0025822963 scopus 로고
    • Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes
    • Aronheim A, Ohlsson H, Park CW, Edlund T, Walker MD 1991 Distribution and characterization of helix-loop-helix enhancer-binding proteins from pancreatic beta cells and lymphocytes. Nucleic Acids Res 19:3893-3899
    • (1991) Nucleic Acids Res , vol.19 , pp. 3893-3899
    • Aronheim, A.1    Ohlsson, H.2    Park, C.W.3    Edlund, T.4    Walker, M.D.5
  • 18
    • 0025971911 scopus 로고
    • Pancreatic β-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins
    • Cordle SR, Henderson E, Masuoka H, Weil PA, Stein R 1991 Pancreatic β-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins. Mol Cell Biol 11:1734-1738
    • (1991) Mol Cell Biol , vol.11 , pp. 1734-1738
    • Cordle, S.R.1    Henderson, E.2    Masuoka, H.3    Weil, P.A.4    Stein, R.5
  • 19
    • 0026016780 scopus 로고
    • Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer
    • German MS, Blanar MA Nelson C, Moss LG, Rutter WJ 1991 Two related helix-loop-helix proteins participate in separate cell-specific complexes that bind the insulin enhancer. Mol Endocrinol 5:292-299
    • (1991) Mol Endocrinol , vol.5 , pp. 292-299
    • German, M.S.1    Blanar, M.A.2    Nelson, C.3    Moss, L.G.4    Rutter, W.J.5
  • 20
    • 0027960493 scopus 로고
    • Two distinct class a helix-loop-helix transcription factors, E2A and BETA 1, form separate DNA-binding complexes on the insulin E-box
    • Peyton M, Moss L, Tsai, M-J 1994 Two distinct class A helix-loop-helix transcription factors, E2A and BETA 1, form separate DNA-binding complexes on the insulin E-box. J Biol Chem 269:25936-25941
    • (1994) J Biol Chem , vol.269 , pp. 25936-25941
    • Peyton, M.1    Moss, L.2    Tsai, M.-J.3
  • 21
    • 0028050241 scopus 로고
    • A novel, pancreatic islet specific transcription factor that binds to and activates expression mediated through insulin enhancer ICE sequences
    • Robinson GLWG, Cordle SR, Henderson E, Weil PA, Teitelman G, Stein R 1994 A novel, pancreatic islet specific transcription factor that binds to and activates expression mediated through insulin enhancer ICE sequences. Mol Cell Biol 14:6704-6714
    • (1994) Mol Cell Biol , vol.14 , pp. 6704-6714
    • Robinson, G.L.W.G.1    Cordle, S.R.2    Henderson, E.3    Weil, P.A.4    Teitelman, G.5    Stein, R.6
  • 22
    • 0028941181 scopus 로고
    • Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor
    • Naya FJ, Stellrecht CMM, Tsai M-J 1995 Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev 9:1009-1019
    • (1995) Genes Dev , vol.9 , pp. 1009-1019
    • Naya, F.J.1    Stellrecht, C.M.M.2    Tsai, M.-J.3
  • 23
    • 0029068316 scopus 로고
    • Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
    • Lee JE, Hollenberg SM, Snider L, Turner DL, Lipnick N, Weintraub H 1995 Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268:836-844
    • (1995) Science , vol.268 , pp. 836-844
    • Lee, J.E.1    Hollenberg, S.M.2    Snider, L.3    Turner, D.L.4    Lipnick, N.5    Weintraub, H.6
  • 24
    • 0025034673 scopus 로고
    • Two distinct transcription factors that bind the immunoglobulin enhancer μE5/κE2 motif
    • Henthorn P, Kiledjian M, Kadesch T 1990 Two distinct transcription factors that bind the immunoglobulin enhancer μE5/κE2 motif. Science 247:467-470
    • (1990) Science , vol.247 , pp. 467-470
    • Henthorn, P.1    Kiledjian, M.2    Kadesch, T.3
  • 25
  • 26
    • 0001032841 scopus 로고
    • McKnight SL, Yamamoto KR (eds), Cold Spring Harbor Laboratory Press, Plainview, NY
    • Murre C, Baltimore D 1992 In: McKnight SL, Yamamoto KR (eds), Transcriptional Regulation. Cold Spring Harbor Laboratory Press, Plainview, NY, pp 861-879
    • (1992) Transcriptional Regulation , pp. 861-879
    • Murre, C.1    Baltimore, D.2
  • 28
    • 0026606084 scopus 로고
    • Fos and Jun repress transcriptional activation by myogenin and MyoD: The amino terminus of jun can mediate repression
    • Li Ll, Chambard J-C, Karin M, Olson EN 1992 Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of jun can mediate repression. Genes Dev 6:676-689
    • (1992) Genes Dev , vol.6 , pp. 676-689
    • Li, Ll.1    Chambard, J.-C.2    Karin, M.3    Olson, E.N.4
  • 29
    • 0028838079 scopus 로고
    • c-Jun inhibits Insulin Control Element mediated transcription by affecting the transactivation potential of the E2A gene products
    • Robinson, GLWG, Henderson E, Massari ME, Murre C, Stein R 1995 c-Jun inhibits Insulin Control Element mediated transcription by affecting the transactivation potential of the E2A gene products. Mol Cell Biol 15:1398-1404
    • (1995) Mol Cell Biol , vol.15 , pp. 1398-1404
    • Robinson, G.L.W.G.1    Henderson, E.2    Massari, M.E.3    Murre, C.4    Stein, R.5
  • 30
    • 0027472051 scopus 로고
    • A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells
    • Quong MW, Massari ME, Zwart R, Murre C 1993 A new transcriptional-activation motif restricted to a class of helix-loop-helix proteins is functionally conserved in both yeast and mammalian cells. Mol Cell Biol 13:792-800
    • (1993) Mol Cell Biol , vol.13 , pp. 792-800
    • Quong, M.W.1    Massari, M.E.2    Zwart, R.3    Murre, C.4
  • 31
    • 0027204066 scopus 로고
    • The E2A gene product contains two separable and functionally distinct transcription activation domains
    • Aronheim A, Shiran R, Rosen A, Walker MD 1993 The E2A gene product contains two separable and functionally distinct transcription activation domains. Proc Natl Acad Sci USA 90:8063-8067
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8063-8067
    • Aronheim, A.1    Shiran, R.2    Rosen, A.3    Walker, M.D.4
  • 32
    • 0029655318 scopus 로고    scopus 로고
    • The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells
    • Massari ME, Jennings PA, Murre C 1996 The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells. Mol Cell Biol 16:121-129
    • (1996) Mol Cell Biol , vol.16 , pp. 121-129
    • Massari, M.E.1    Jennings, P.A.2    Murre, C.3
  • 33
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang Y, Soriano P, Weintraub H 1994 The helix-loop-helix gene E2A is required for B cell formation. Cell 79:875-884
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 35
    • 0029896451 scopus 로고    scopus 로고
    • B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
    • Zhuang Y, Cheng P, Weintraub H 1996 B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol Cell Biol 16:2898-2905
    • (1996) Mol Cell Biol , vol.16 , pp. 2898-2905
    • Zhuang, Y.1    Cheng, P.2    Weintraub, H.3
  • 36
    • 0028831207 scopus 로고
    • The Pan basic heleix-loop-helix proteins are required for insulin gene expression
    • Vierra, CA, Nelson C 1995 The Pan basic heleix-loop-helix proteins are required for insulin gene expression. Mol Endocrinol 9:64-71
    • (1995) Mol Endocrinol , vol.9 , pp. 64-71
    • Vierra, C.A.1    Nelson, C.2
  • 37
    • 0031013331 scopus 로고    scopus 로고
    • Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice
    • Stellrecht CMM, Demayo FJ, Finegold MJ, Tsai M-J 1997 Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice. J Biol Chem 272:3567-3572
    • (1997) J Biol Chem , vol.272 , pp. 3567-3572
    • Stellrecht, C.M.M.1    Demayo, F.J.2    Finegold, M.J.3    Tsai, M.-J.4
  • 38
    • 0029912857 scopus 로고    scopus 로고
    • Phosphorylation of E47 as a potential determinant of B-cell-specific activity
    • Sloan SR, Shen CP, McCarrick-Walmsley R, Kadesch, T 1996 Phosphorylation of E47 as a potential determinant of B-cell-specific activity. Mol Cell Biol 16:6900-6908
    • (1996) Mol Cell Biol , vol.16 , pp. 6900-6908
    • Sloan, S.R.1    Shen, C.P.2    McCarrick-Walmsley, R.3    Kadesch, T.4
  • 40
    • 0026020867 scopus 로고
    • An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not E12 heterodimers
    • Sun X-H, Baltimore D 1991 An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not E12 heterodimers. Cell 64: 459-470
    • (1991) Cell , vol.64 , pp. 459-470
    • Sun, X.-H.1    Baltimore, D.2
  • 41
    • 0025060420 scopus 로고
    • Sequence of the cDNA encoding ITF-1, a positive-acting transcription factor
    • Henthorn P, McCarrick-Walmsley R, Kadesch T 1990 Sequence of the cDNA encoding ITF-1, a positive-acting transcription factor. Nucleic Acids Res 18:677
    • (1990) Nucleic Acids Res , vol.18 , pp. 677
    • Henthorn, P.1    McCarrick-Walmsley, R.2    Kadesch, T.3
  • 42
    • 0025256997 scopus 로고
    • Identification of a pancreatic β-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: Its possible relationship to other cellular factors that bind to a common insulin gene sequence
    • Whelan J, Cordle SR, Henderson E, Weil PA, Stein R 1990 Identification of a pancreatic β-cell insulin gene transcription factor that binds to and appears to activate cell-type-specific expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence. Mol Cell Biol 10:1564-1572
    • (1990) Mol Cell Biol , vol.10 , pp. 1564-1572
    • Whelan, J.1    Cordle, S.R.2    Henderson, E.3    Weil, P.A.4    Stein, R.5
  • 43
    • 0026331306 scopus 로고
    • Insulin gene expression in non-expressing cells appears to be regulated by multiple, distinct, negative acting control elements
    • Cordle S, Whelan J, Henderson E, Masuoka H, Weil PA, Stein R 1991 Insulin gene expression in non-expressing cells appears to be regulated by multiple, distinct, negative acting control elements. Mol Cell Biol 11: 2881-2886
    • (1991) Mol Cell Biol , vol.11 , pp. 2881-2886
    • Cordle, S.1    Whelan, J.2    Henderson, E.3    Masuoka, H.4    Weil, P.A.5    Stein, R.6
  • 44
    • 0028136103 scopus 로고
    • Analysis of transcription regulatory signals of the insulin gene: Expression of the trans-active factor that stimulates insulin control element mediated expression precedes insulin gene transcription
    • Robinson GLWG, Cordle SR, Henderson E, Weil PA, Teitelman G, Stein R 1994 Analysis of transcription regulatory signals of the insulin gene: expression of the trans-active factor that stimulates insulin control element mediated expression precedes insulin gene transcription. J Biol Chem 269:2452-2460
    • (1994) J Biol Chem , vol.269 , pp. 2452-2460
    • Robinson, G.L.W.G.1    Cordle, S.R.2    Henderson, E.3    Weil, P.A.4    Teitelman, G.5    Stein, R.6
  • 45
    • 0029763995 scopus 로고    scopus 로고
    • mRNA profiling of rat islet tumors reveals Nkx 6.1 as a beta-cell-specific homeodomain transcription factor
    • Jensen J, Serup P, Karlsen C, Nielsen TF, Madsen OD 1996 mRNA profiling of rat islet tumors reveals Nkx 6.1 as a beta-cell-specific homeodomain transcription factor. J Biol Chem 271:18749-18758
    • (1996) J Biol Chem , vol.271 , pp. 18749-18758
    • Jensen, J.1    Serup, P.2    Karlsen, C.3    Nielsen, T.F.4    Madsen, O.D.5
  • 47
    • 0023127059 scopus 로고
    • Laboratory Methods. A Rapid, Sensitive, and Inexpensive Assay for Chloramphenicol Acetyltransferase
    • Nordeen SK, Green PPI II, Fowles DM 1987 Laboratory Methods. A Rapid, Sensitive, and Inexpensive Assay for Chloramphenicol Acetyltransferase. DNA 6: 173-178
    • (1987) DNA , vol.6 , pp. 173-178
    • Nordeen, S.K.1    Green II, P.P.I.2    Fowles, D.M.3
  • 48
    • 0024394549 scopus 로고
    • Cloning, structure and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
    • Andersson S, Davis DL, Dahlback H, Jornvall H, Russell DW 1989 Cloning, structure and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem 264:8222-8229
    • (1989) J Biol Chem , vol.264 , pp. 8222-8229
    • Andersson, S.1    Davis, D.L.2    Dahlback, H.3    Jornvall, H.4    Russell, D.W.5
  • 49
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W 1989 Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells. Nucleic Acids Res 17:6419
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4


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