Functional involvement of polypyrimidine tract-binding protein in translation initiation complexes with the internal ribosome entry site of foot-and-mouth disease virus

Journal of Virology

Volumn 71, Issue 11, 1997, Pages 8330-8339

  Niepmann, Michael ^a   Petersen, Anke ^a,b   Meyer, Karsten ^a,c   Beck, Ewald ^a  

^a Institut fur Biochemie   (Germany)

^b Innovex (Biodesign) GmbH   (Germany)

^c IQVIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN;

ARTICLE; BINDING SITE; FOOT AND MOUTH DISEASE VIRUS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; RIBOSOME; TRANSLATION INITIATION;

EID: 0030766564     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.11.8330-8339.1997     Document Type: Article

References (52)

1. Ali, N., and A. Siddiqui. 1995. Interaction of polypyrimidine tract binding protein with the 5′-noncoding region of the hepatitis C virus genome and its functional requirement in internal initiation of translation. J. Virol. 69:6367-6375.
2. Anthony, D. D., and W. C. Merrick. 1991. Eukaryotic initiation factor eIF-4F. J. Biol. Chem. 266:10218-10226.
3. Anthony, D. D., and W. C. Merrick. 1992. Analysis of 40S and 80S complexes with mRNA as measured by sucrose density gradients and primer extension inhibition. J. Biol. Chem. 267:1554-1562.
4. Belsham, G. J., and N. Sonenberg. 1496. RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol. Rev. 60:499-511.
5. Blyn, L. B., K. M. Swiderek, O. Richards, D. C. Stahl, B. L. Semler, and E. Ehrenfeld. 1996. Poly(rC) binding protein 2 binds to stem-loop IV of the poliovirus RNA 5′-noncoding region: identification by automated liquid chromatography-tandem mass spectrometry. Proc. Natl. Acad. Sci. USA 93:11115-11120.
6. Borman, A., M. T. Howell, J. G. Patton, and R. J. Jackson. 1993. The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. J. Gen. Virol. 74:1775-1788.
7. Borman, A. M., J.-L. Bailly, M. Girard, and K. M. Kean. 1995. Picornavirus internal ribosome entry segments: comparison of translation efficiency and the requirements for optimal internal initiation of translation in vitro. Nucleic Acids Res. 23:3656-3663.
8. Borovjagin, A. V., M. V. Ezrokhi, V. M. Rostapshov, T. Y. Ugarova, T. F. Bystrova, and I. N. Shatsky. 1991. RNA-protein interactions within the internal translation initiation region of encephalomyocarditis virus RNA. Nucleic Acids Res. 19:4999-5005.
9. Borovjagin, A. V., T. V. Pestova, and I. N. Shatsky. 1994. Pyrimidine tract binding protein strongly stimulates in vitro encephalomyocarditis virus RNA translation at the level of preinitiation complex formation. FEBS Lett 351:299-302.
10. Brown, B., and E. Ehrenfeld. 1979. Translation of poliovirus RNA in vitro: changes in cleavage pattern and initiation sites by ribosomal salt wash. Virology 97:396-405.
11. Cassinotti, P., and M. Weitz. 1994. Increasing the sensitivity of a common CAT assay. BioTechniques 17:36,38,40.
12. Gil, A., P. A. Sharp, S. F. Jamison, and M. A. Garçia-Blanco. 1991. Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev. 5:1224-1236.
13. Gingras, A.-C., Y. Svitkin, G. J. Belsham, A. Pause, and N. Sonenberg. 1996. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proc. Natl. Acad. Sci. USA 93: 5578-5583.
14. Glass, M. J., and D. F. Summers. 1993. Identification of a trans-cting activity from liver that stimulates hepatitis A virus translation in vitro. Virology 193:1047-1050.
15. Golini, F., S. S. Thach, C. H. Birge, B. Safer, W. C. Merrick, and R. E. Thach. 1976. Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory factor. Proc. Natl. Acad. Sci. USA 73:3040-3044.
16. Hellen, C. U. T., G. W. Witherell, M. Schmid, S. H. Shin, T. V. Pestova, A. Gil, and E. Wimmer. 1993. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc. Natl. Acad. Sci. USA 90:7642-7646.
17. Hellen, C. U. T., T. V. Pestova, M. Litterst, and E. Wimmer. 1994. The cellular polypeptide p57 (pyrimidine tract-binding protein) binds to multiple sites in the poliovirus 5′-nontranslated region. J. Virol. 68:941-950.
18. Jackson, R. J., and A. Kaminski. 1995. Internal initiation of translation in eukaryotes: the picornavirus paradigm and beyond. RNA 1:985-1000.
19. Jang, S. K., H. Kräusslich, M. J. Nicklin, G. M. Duke, A. C. Palmenberg, and E. Wimmer. 1988. A segment of the 5′ nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J. Virol. 62:2636-2643.
20. Jang, S. K., and E. Wimmer. 1990. Cap independent translation of encephalomyocarditis virus RNA: structural elements of the internal ribosomal entry site and involvement of a cellular 57 kDa RNA-binding protein. Genes Dev. 4:1560-1572.
21. Jen, G., and R. E. Thach. 1982. Inhibition of host translation in encephalomyocarditis virus-infected L cells: a novel mechanism. J. Virol. 43:250-261.
22. Junker-Niepmann, M., R. Bartenschlager, and H. Schaller. 1990. A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA. EMBO J. 9:3389-3396.
23. Kaminski, A., S. L. Hunt, J. G. Patton, and R. J. Jackson. 1995. Direct evidence that polypyrimidine tract-binding protein (PTB) is essential for internal initiation of translation of encephalomyocarditis virus RNA. RNA 1:924-938.
24. Kiledjian, M., and G. Dreyfuss. 1992. Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11: 2655-2664.
25. Kolupaeva, V. G., C. U. T. Hellen, and I. N. Shatsky. 1996. Structural analysis of the interaction of the pyrimidine tract binding protein with the internal ribosomal entry site of encephalomyocarditis virus and foot-and-mouth disease virus RNAs. RNA 2:1199-1212.
26. Kühn, R., N. Luz, and E. Beck. 1990. Functional analysis of the internal translation initiation site of foot-and-mouth disease virus. J. Virol. 64:4625-4631.
27. Kunkel, T. A. 1985. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. USA 82:488-492.
28. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
29. Luz, N., and E. Beck. 1990. A cellular 57 kDa protein binds two regions of the internal translation initiation site of foot-and-mouth disease virus. FEBS Lett. 269:311-314.
30. Luz, N., and E. Beck. 1991. Interaction of a cellular 57-kilodalton protein with the internal translation initiation site of foot-and-mouth disease virus. J. Virol. 65:6486-6494.
31. Meerovitch, K., Y. V. Svitkin, H. S. Lee, F. Lejbkowicz, D. J. Kenan, E. K. L. Chan, V. I. Agol, J. D. Keene, and N. Sonenberg. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:3798-3807.
32. Melton, D. A., P. A. Krieg, R. Rebagliati, T. Maniatis, K. Zinn, and M. R. Green. 1984. Efficient in vitro synthesis of biologically active RNA and RNA hybridization from plasmid containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:7035-7056.
33. Meyer, K., A. Petersen, M. Niepmann, and E. Beck. 1995. Interaction of eukaryotic initiation factor 4B with a picornaviral internal translation initiation site. J. Virol. 69:2819-2824.
34. Nelson, E. M., and M. M. Winkler. 1987. Regulation of mRNA entry into polysomes. J. Biol. Chem. 262:11501-11506.
35. Niepmann, M. 1996. Porcine polypyrimidine tract-binding protein stimulates translation initiation at the internal ribosome entry site of foot-and-mouth-disease virus. FEBS Lett. 388:39-12.
36. Niepmann, M. Unpublished results.
37. Pause, A., N. Méthot, Y. Svitkin, W. C. Merrick, and N. Sonenberg. 1994. Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation. EMBO J. 13:1205-1215.
38. Pelletier, J., and N. Sonenberg. 1988. Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA. Nature 334:320-325.
39. Pelletier, J., M. E. Flynn, G. Kaplan, V. R. Racaniello, and N. Sonenberg. 1988. Mutational analysis of upstream AUG codons of poliovirus RNA. J. Virol. 62:4486-4492.
40. Pestova, T. V., C. U. T. Hellen, and E. Wimmer. 1991. Translation of polio-virus RNA: role of an essential cis-acting oligopyrimidine element within the 5′ nontranslated region and involvement of a cellular 57-kilodalton protein. J. Virol. 65:6194-6204.
41. Pestova, T. V., C. U. T. Hellen, and I. N. Shatsky. 1996. Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry. Mol. Cell. Biol. 16:6859-6869.
42. Pestova, T. V., I. N. Shatsky, and C. U. T. Hellen. 1996. Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes. Mol. Cell. Biol. 16:6870-6878.
43. Pilipenko, E. V., V. M. Blinov, B. K. Chernow, T. M. Dmitrieva, and V. I. Agol. 1989. Conservation of the secondary structure elements of the 5′-untranslated region of cardio- and aphthovirus RNA. Nucleic Acids Res. 17:5701-5711.
44. Pilipenko, E. V., A. P. Gmyl, S. V. Maslova, G. A. Belov, A. N. Sinyakov, M. Huang, T. D. K. Brown, and V. I. Agol. 1994. Starting window, a distinct element in the cap-independent internal initiation of translation on picornaviral RNA. J. Mol. Biol. 241:398-414.
45. Scheper, G. C., H. O. Voorma, and A. A. M. Thomas. 1992. Eukaryotic initiation factors-4E and -4F stimulate 5′ cap-dependent as well as internal initiation of protein synthesis. J. Biol. Chem. 267:7269-7274.
46. Schultz, D. E., C. C. Hardin, and S. M. Lemon. 1996. Specific interaction of glyceraldehyde 3-phosphate dehydrogenase with the 5′-nontranslated RNA of hepatitis A virus. J. Biol. Chem. 271:14134-14142.
47. Seed, B., and J. Y. Sheen. 1988. A simple phase-extraction assay for chloramphenicol acetyltransferase activity. Gene 67:271-277.
48. Smith, D. B., and K. S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
49. Svitkin, Y. V., K. Meerovitch, H. S. Lee, J. N. Dholakia, D. J. Kenan, V. I. Agol, and N-Sonenberg. 1994. Internal translation initiation on poliovirus RNA: further characterization of La function in poliovirus translation in vitro. J. Virol. 68:1544-1550.
50. Svitkin, Y. V., L. P. Ovchinnikov, G. Dreyfuss, and N. Sonenberg. 1996. General RNA binding proteins render translation cap dependent. EMBO J. 15:7147-7155.
51. Timmer, R. T., L. A. Benkowski, J. M. Ravel, and K. S. Browning. 1995. Determination of the amounts of protein synthesis initiation factors required for translation of rabbit a-globin and β-globin mRNAs. Biochem. Biophys. Res. Commun. 210:370-377.
52. Witherell, G. W., A. Gil, and E. Wimmer. 1993. Interaction of polypyrimidine tract binding protein with the encephalomyocarditis virus mRNA internal ribosome entry site. Biochemistry 32:8268-8275.