Telomerase activity and metastasis: Expansion of cells having higher telomerase activity within culture lines and tumor tissues

Japanese Journal of Cancer Research

Volumn 88, Issue 8, 1997, Pages 732-737

  Saito, Yoshiyuki ^a   Kosugi, Shin Ichi ^a   Suda, Takeshi ^a   Wakabayashi, Yuichi ^a   Mishima, Yukio ^a   Hatakeyama, Katsuyoshi ^a   Kominami, Ryo ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

Metastasis; Telomerase activity; Telomere

Indexed keywords

REPETITIVE DNA; TELOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER TRANSPLANTATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FIBROSARCOMA; MALE; METASTASIS; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL;

EID: 0030764390     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1997.tb00444.x     Document Type: Article

References (45)

1. Moyzis, R. K., Buckingham, J. M., Cram, S., Dani, M., Deaven, L. L., James, M. D., Meyne, J., Ratliff, R. L. and Wu, J. R. A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomere of human chromosomes. Proc. Natl. Acad. Sci. USA, 85, 6622-6626 (1988).
2. Blackburn, E. H. Structure and function of telomeres. Nature, 350, 569-573 (1991).
3. Zakian, V. A. Structure and function of telomeres. Annu. Rev. Genet., 23, 579-604 (1989).
4. Rhyu, M. S. Telomeres, telomerase, and immortality. J. Natl. Cancer Inst., 87, 884-895 (1995).
5. Harley, C. B., Futcher, A. B. and Greider, C. W. Telomeres shorten during aging of human fibroblasts. Nature, 345, 458-460 (1990).
6. Hastie, N. D., Dempster, M., Dunlop, M. G., Thompson, A. M., Green, D. K. and Allshire, R. C. Telomere reduction in human colorectal carcinoma and with aging. Nature, 346, 866-868 (1990).
7. Lundbald, V. and Szostak, J. W. A mutant with a defect in telomere elongation leads to senescence in yeast. Cell, 57, 633-643 (1989).
8. Greider, C. W. and Blackburn, E. H. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell, 51, 887-898 (1987).
9. Morin, G. B. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell, 59, 521-529 (1989).
10. Kim, N. W., Piatyszek, M. A., Prowse, K. R., Harley, C. B., West, M. D., Ho, P. L. C., Coviello, G. M., Wright, W. E., Weinrich, S. L. and Shay, J. W. Specific association of human telomerase activity with immortal cells and cancer. Science, 266, 2011-2015 (1994).
11. Counter, C. M., Hirte, H. W., Bacchetti, S. and Halrey, C. Telomerase activity in human ovarian carcinoma. Proc. Natl. Acad. Sci. USA, 91, 2900-2904 (1994).
12. Hiyama, K., Hiyama, E., Ishioka, S., Yamada, M., Inai, K., Gazdar, A. F., Piatyszek, M. A. and Shay, J. W. Telomerase activity in small-cell and non-small-cell lung cancers. J. Natl. Cancer Inst., 87, 895-902 (1995).
13. Chadeneau, C., Hay, K., Hirte, H. W., Steven, G. and Silvia, B. Telomerase activity associated with acquisition of malignancy in human colorectal cancer. Cancer Res., 55, 2533-2536 (1995).
14. Tahara, H., Nakanishi, T., Kitamoto, M., Nakashio, R., Shay, J. W., Tahara, E., Kajiyama, G. and Ide, T. Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res., 55, 2734-2736 (1995).
15. Hiyama, E., Yokoyama, T., Tatsumoto, N., Hiyama, K., Imamura, Y., Murakami, Y., Kodama, T., Piatyszek, M. A., Shay, J. W. and Matsuura, Y. Telomerase activity in gastric cancer. Cancer Res., 55, 3258-3262 (1995).
16. Hiyama, E., Gollahon, L., Takaoka, T. and Shay, J. Telomerase activity in human breast tumors. J. Natl. Cancer Inst., 88, 116-122 (1996).
17. Hiyama, K., Hirai, Y., Kyoizumi, S., Akiyama, M., Hiyama, E., Piatyszek, M. A., Shay, J. W., Ishikawa, S. and Yamada, M. Activation of telomerase in human lymphocytes and hematopoietic progenitor. J. Immunol., 155, 3711-3715 (1995).
18. Broccoli, D., Youneg, J. W. and de Lange, T. Telomerase activity in normal and malignant hematopoietic cells. Proc. Natl. Acad. Sci. USA, 92, 9082-9086 (1995).
19. Hiyama, E., Hiyama, K., Yokoyama, T., Yokoyama, T., Matsuura, Y., Piatyszek, M. A. and Shay, J. W. Correlating telomerase activity levels with human neuroblastoma outcomes. Nat. Med., 1, 249-255 (1995).
20. Chadeneau, C., Siegel, P., Harley, C. B., Muller, W. J. and Bacchetti, S. Telomerase activity in normal and malignant murine tissues. Oncogene, 11, 893-898 (1995).
21. Broccoli, D., Godley, L. A., Donehower, L. A., Varmus, H. E. and de Lange, T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation. Mol. Cell. Biol., 16, 3765-3772 (1996).
22. Blasco, M., Rizen, M., Greider, C. W. and Hanahan, D. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nat. Genet., 12, 200-204 (1996).
23. Ogoshi, M., Takashima, A. and Taylor, R. S. Mechanisms regulating telomere activity in murine T cells. J. Immunol., 158, 622-628 (1997).
24. Ohtsuka, H., Mafune, Y., Tsunashima, K., Takahashi, H. and Kominami, R. Difference in allelic expression of genes probably associated with tumor progression in murine fibrosarcomas and cell lines. Jpn. J. Cancer Res., 85, 1015-1022 (1994).
25. Ohyashiki, J. H., Ohyashiki, K., Sano, T. and Toyama, K. Non-radioisotopic and semi-quantitative procedure for terminal repeat amplification protocol. Jpn. J. Cancer Res., 87, 329-331 (1996).
26. Hayashi, T., Mafune, Y., Takada, T., Hatakeyama, K., Takagi, N. and Kominami, R. Telomere change and loss of heterozygosity of mouse primary tumors and cell lines. Jpn. J. Cancer Res., 84, 1292-1299 (1993).
27. Hayashi, T., Ohtsuka, H., Kuwabara, K., Mafune, Y., Miyashita, N., Moriwaki, K., Takahashi, Y. and Kominami, R. A variant family of mouse minor satellite located on the centromeric region of chromosome 2. Genomics, 17, 490-492 (1993).
28. Mitani, K., Takahashi, Y. and Kominami, R. A GGCAGG motif in minisatellites affecting their germline instability. J. Biol. Chem., 265, 15203-15210 (1990).
29. Kipling, D. and Cooke, H. J. Hypervariable ultra-long telomeres in mice. Nature, 347, 400-402 (1990).
30. Starling, J. A., Maule, J., Hastie, N. D. and Allshire, R. C. Extensive telomere repeat arrays in mouse are hypervariable. Nucleic Acids Res., 18, 6881-6888 (1990).
31. Kipling, D., Ackford, H. E., Taylor, B. A. and Cooke, H. J. Mouse minor satellite DNA genetically maps to the centromere and is physically linked to the proximal telomere. Genomics, 11, 235-241 (1991).
32. Nowell, P. Mechanisms of tumor progression. Cancer Res., 46, 2203-2207 (1986).
33. Wainscoat, J. S. and Fey, M. F. An assessment of clonality in human tumors: a review. Cancer Res., 50, 1355-1360 (1990).
34. Mafune, Y., Asakura, H. and Kominami, R. Allelic losses and metastatic ability of mouse tumor cell clones derived from a heterozygous mouse. Oncogene, 9, 2191-2196 (1994).
35. Holt, S. H., Wright, W. and Shay, J. W. Regulation of telomerase activity in immortal cell lines. Mol. Cell. Biol., 16, 2932-2939 (1996).
36. Chadeneau, C., Siegel, P., Harley, C. B., Müller, J. W. and Bacchetti, S. Telomerase activity in normal and malignant murine tissues. Oncogene, 11, 893-898 (1995).
37. Burger, A. M., Bibby, M. C. and Double, J. A. Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy. Br. J. Cancer, 75, 516-522 (1997).
38. Zakian, V. A. Saccharomyces telomeres: function, structure and replication. In "Telomeres," ed. E. H. Blackburn and C. W. Greider, pp. 107-138 (1995). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
39. Conrad, M. N., Wright, J. H., Wolf, A. J. and Zakian, A. RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell, 63, 739-750 (1990).
40. Sandell, L. L. and Zakian, V. A. Loss of yeast telomere: arrest, recovery, and chromosome loss. Cell, 75, 729-739 (1993).
41. de Lange, T. Activation of telomerase in a human tumor. Proc. Natl. Acad. Sci. USA, 91, 2882-2885 (1994).
42. van Steensel, B. and de Lange, T. Control of telomere length by the human telomere binding protein TRF1. Nature, 385, 740-743 (1997).
43. Kyrion, G., Boakye, K. A. and Lustig, A. J. C-Terminal truncation of RAP1 results in the deregulatation of telomere size, stability, and function in Saccharomyces cerevisiae. Mol. Cell. Biol., 12, 5159-5173 (1992).
44. Greenwell, P. W., Kronmal, S. L., Porter, S. E., Gassenhuber, J., Obermaier, B. and Peters, T. D. TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. Cell, 82, 823-829 (1995).
45. Cooper, J. P., Nimmo, E. R., Allshire, R. C. and Cech, T. R. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature, 385, 744-747 (1997).