메뉴 건너뛰기




Volumn 80, Issue 3 A, 1997, Pages 41A-49A

Multiple signaling pathways involved in the metabolic effects of insulin

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CASEIN KINASE III; EPIDERMAL GROWTH FACTOR; FATTY ACID; GLYCOGEN; GLYCOGEN SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHODIESTERASE; PROTEIN KINASE; PYRUVATE DEHYDROGENASE; RAPAMYCIN; RAS PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0030763751     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(97)00457-8     Document Type: Conference Paper
Times cited : (66)

References (62)
  • 1
    • 0342860512 scopus 로고
    • Actions of insulin on intracellular processes
    • K.G.M.M. Alberti, R.A. DeFronzo, H. Keen, & P. Zimmet. Chichester, UK: John Wiley
    • Denton RM, Tavaré JM. Actions of insulin on intracellular processes. Alberti KGMM, DeFronzo RA, Keen H, Zimmet P. International Textbook of Diabetes Mellitus. 1992;385-408 John Wiley, Chichester, UK.
    • (1992) International Textbook of Diabetes Mellitus , pp. 385-408
    • Denton, R.M.1    Tavaré, J.M.2
  • 2
    • 0028085078 scopus 로고
    • The insulin signaling system
    • White MF, Kahn CR. The insulin signaling system. J Biol Chem. 269:1994;1-4.
    • (1994) J Biol Chem , vol.269 , pp. 1-4
    • White, M.F.1    Kahn, C.R.2
  • 3
    • 0027170056 scopus 로고
    • Mutational analysis of insulin receptor function - Consensus and controversy
    • Tavaré JM, Siddle K. Mutational analysis of insulin receptor function - consensus and controversy. Biochim Biophys Acta. 1178:1993;21-39.
    • (1993) Biochim Biophys Acta , vol.1178 , pp. 21-39
    • Tavaré, J.M.1    Siddle, K.2
  • 4
    • 0029924856 scopus 로고    scopus 로고
    • Insulin signal transduction and the IRS proteins
    • Myers MG, White MF. Insulin signal transduction and the IRS proteins. Annu Rev Pharmacol Toxicol. 36:1996;615-658.
    • (1996) Annu Rev Pharmacol Toxicol , vol.36 , pp. 615-658
    • Myers, M.G.1    White, M.F.2
  • 5
    • 0028891049 scopus 로고
    • Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against
    • Denton RM, Tavaré JM. Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against. Eur J Biochem. 227:1995;597-611.
    • (1995) Eur J Biochem , vol.227 , pp. 597-611
    • Denton, R.M.1    Tavaré, J.M.2
  • 6
    • 0028223704 scopus 로고
    • Dissociation between the activation of Raf-1 kinase and the MAP-kinase cascade in the insulin/Ras pathway of adipocyte differentiation of 3T3 L1 cells
    • Porras A, Muszynski K, Rapp UR, Santos E. Dissociation between the activation of Raf-1 kinase and the MAP-kinase cascade in the insulin/Ras pathway of adipocyte differentiation of 3T3 L1 cells. J Biol Chem. 269:1994;12741-12748.
    • (1994) J Biol Chem , vol.269 , pp. 12741-12748
    • Porras, A.1    Muszynski, K.2    Rapp, U.R.3    Santos, E.4
  • 7
    • 0030581475 scopus 로고    scopus 로고
    • Raf gets it together
    • Marshall CJ. Raf gets it together. Nature. 388:1996;127-128.
    • (1996) Nature , vol.388 , pp. 127-128
    • Marshall, C.J.1
  • 8
    • 0028095620 scopus 로고
    • Structure, regulation and function of phosphoinositide 3-kinases
    • Fry MJ. Structure, regulation and function of phosphoinositide 3-kinases. Biochim Biophys Acta. 1226:1994;237-268.
    • (1994) Biochim Biophys Acta , vol.1226 , pp. 237-268
    • Fry, M.J.1
  • 9
    • 0029143388 scopus 로고
    • Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing Ser/Thr kinase
    • Kohn AB, Kovacina KS, Roth RA. Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing Ser/Thr kinase. EMBO J. 14:1995;4288-4295.
    • (1995) EMBO J , vol.14 , pp. 4288-4295
    • Kohn, A.B.1    Kovacina, K.S.2    Roth, R.A.3
  • 11
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin-mediated by protein kinase B
    • Cross DAE, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin-mediated by protein kinase B. Nature. 378:1995;785-789.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 12
    • 0029810181 scopus 로고    scopus 로고
    • Akt, a pleckstrin homology domain containing kinase is activated primarily by phosphorylation
    • Kohn AD, Takeuchi F, Roth RA. Akt, a pleckstrin homology domain containing kinase is activated primarily by phosphorylation. J Biol Chem. 271:1996;21920-21926.
    • (1996) J Biol Chem , vol.271 , pp. 21920-21926
    • Kohn, A.D.1    Takeuchi, F.2    Roth, R.A.3
  • 13
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BMT, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 376:1995;599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 15
    • 0028032895 scopus 로고
    • Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene
    • Araki E, Lipes MA, Patti M, Bruning JC, Haag B, Johnson RS, Kahn CR. Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene. Nature. 372:1994;186-190.
    • (1994) Nature , vol.372 , pp. 186-190
    • Araki, E.1    Lipes, M.A.2    Patti, M.3    Bruning, J.C.4    Haag, B.5    Johnson, R.S.6    Kahn, C.R.7
  • 21
    • 0027935491 scopus 로고
    • Activation of ribosomal protein S6 kinases does not increase glycogen synthesis or glucose transport in rat adipocytes
    • Lin TA, Lawrence JC. Activation of ribosomal protein S6 kinases does not increase glycogen synthesis or glucose transport in rat adipocytes. J Biol Chem. 269:1994;21255-21261.
    • (1994) J Biol Chem , vol.269 , pp. 21255-21261
    • Lin, T.A.1    Lawrence, J.C.2
  • 22
    • 0027485031 scopus 로고
    • Increasing cAMP concentration attenuates activation of MAP-kinase
    • Sevetson BR, Kong XM, Lawrence JC. Increasing cAMP concentration attenuates activation of MAP-kinase. Proc Natl Acad Sci USA. 90:1993;10305-10309.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10305-10309
    • Sevetson, B.R.1    Kong, X.M.2    Lawrence, J.C.3
  • 23
    • 0027978816 scopus 로고
    • The inhibition of glycogen synthase kinase 3 by insulin or insulin-like growth factor-1 in rat skeletal muscle cell line L6 is blocked by wortmannin, but not rapamycin
    • Cross DAE, Alessi DR, Vandenheede JR, McDowell HE, Hundel HS, Cohen P. The inhibition of glycogen synthase kinase 3 by insulin or insulin-like growth factor-1 in rat skeletal muscle cell line L6 is blocked by wortmannin, but not rapamycin. Biochem J. 303:1994;21-26.
    • (1994) Biochem J , vol.303 , pp. 21-26
    • Cross, D.A.E.1    Alessi, D.R.2    Vandenheede, J.R.3    McDowell, H.E.4    Hundel, H.S.5    Cohen, P.6
  • 24
    • 0027991899 scopus 로고
    • Wortmannin inhibits the effect of insulin and serum on the activities of glycogen synthase kinase-3 and MAP-kinase
    • Welsh GI, Foulstone EJ, Young SW, Tavaré JM, Proud CG. Wortmannin inhibits the effect of insulin and serum on the activities of glycogen synthase kinase-3 and MAP-kinase. Biochem J. 303:1994;15-20.
    • (1994) Biochem J , vol.303 , pp. 15-20
    • Welsh, G.I.1    Foulstone, E.J.2    Young, S.W.3    Tavaré, J.M.4    Proud, C.G.5
  • 25
    • 0027374488 scopus 로고
    • Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
    • Yano H, Nakanishi S, Kimura K, Hanai N, Saiton Y, Fukui Y, Nonomura Y, Matsuda Y. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J Biol Chem. 268:1993;25846-25856.
    • (1993) J Biol Chem , vol.268 , pp. 25846-25856
    • Yano, H.1    Nakanishi, S.2    Kimura, K.3    Hanai, N.4    Saiton, Y.5    Fukui, Y.6    Nonomura, Y.7    Matsuda, Y.8
  • 27
    • 0028124189 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin induced glucose transport and antilipolysis in rat adipocytes - Studies with a selective inhibitor wortmannin
    • Okada T, Kawano Y, Sakakibara T, Hazeki O, Ui M. Essential role of phosphatidylinositol 3-kinase in insulin induced glucose transport and antilipolysis in rat adipocytes - studies with a selective inhibitor wortmannin. J Biol Chem. 269:1994;3568-3573.
    • (1994) J Biol Chem , vol.269 , pp. 3568-3573
    • Okada, T.1    Kawano, Y.2    Sakakibara, T.3    Hazeki, O.4    Ui, M.5
  • 28
    • 0028308412 scopus 로고
    • Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
    • Cheatham B, Vlahos CJ, Cheatham L, Wang L, Blenis J, Kahn CR. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol Cell Biol. 14:1994;4902-4911.
    • (1994) Mol Cell Biol , vol.14 , pp. 4902-4911
    • Cheatham, B.1    Vlahos, C.J.2    Cheatham, L.3    Wang, L.4    Blenis, J.5    Kahn, C.R.6
  • 31
    • 0029981389 scopus 로고    scopus 로고
    • Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves MAP-kinase independent and rapamycin-sensitive pathways
    • Azpiazu I, Saltiel AR, DePaoli-Roach AA, Lawrence JC. Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves MAP-kinase independent and rapamycin-sensitive pathways. J Biol Chem. 271:1996;5033-5039.
    • (1996) J Biol Chem , vol.271 , pp. 5033-5039
    • Azpiazu, I.1    Saltiel, A.R.2    Depaoli-Roach, A.A.3    Lawrence, J.C.4
  • 33
    • 0027420730 scopus 로고
    • The glucose transporter family - Structure, function and tissue-specific expression
    • Gould GW, Holman GD. The glucose transporter family - structure, function and tissue-specific expression. Biochem J. 295:1993;329-341.
    • (1993) Biochem J , vol.295 , pp. 329-341
    • Gould, G.W.1    Holman, G.D.2
  • 34
    • 0024955859 scopus 로고
    • Studies into the mechanism whereby insulin activates pyruvate dehydrogenase complex in adipose tissue
    • Denton RM, Midgley PJN, Rutter GA, Thomas AP, McCormack JG. Studies into the mechanism whereby insulin activates pyruvate dehydrogenase complex in adipose tissue. Ann N Y Acad Sci. 573:1989;285-296.
    • (1989) Ann N Y Acad Sci , vol.573 , pp. 285-296
    • Denton, R.M.1    Midgley, P.J.N.2    Rutter, G.A.3    Thomas, A.P.4    McCormack, J.G.5
  • 35
    • 77956902317 scopus 로고
    • Acetyl-CoA carboxylase
    • Brownsey RW, Denton RM. Acetyl-CoA carboxylase. Enzymes. 18B:1987;123-146.
    • (1987) Enzymes , vol.18 , pp. 123-146
    • Brownsey, R.W.1    Denton, R.M.2
  • 36
    • 0025708333 scopus 로고
    • Protein serine kinase from rat epididymal adipose tissue which phosphorylates and activates acetyl-CoA carboxylase. Possible role in insulin action
    • Borthwick AC, Edgell NJ, Denton RM. Protein serine kinase from rat epididymal adipose tissue which phosphorylates and activates acetyl-CoA carboxylase. Possible role in insulin action. Biochem J. 270:1990;795-801.
    • (1990) Biochem J , vol.270 , pp. 795-801
    • Borthwick, A.C.1    Edgell, N.J.2    Denton, R.M.3
  • 37
    • 0027194749 scopus 로고
    • Dissection of the protein phosphorylation cascades involved in insulin and growth factor action
    • Cohen P. Dissection of the protein phosphorylation cascades involved in insulin and growth factor action. Biochem Soc Trans. 21:1993;555-567.
    • (1993) Biochem Soc Trans , vol.21 , pp. 555-567
    • Cohen, P.1
  • 38
    • 0026591098 scopus 로고
    • Signal transduction and protein phosphorylation in the regulation of cellular metabolism by insulin
    • Lawrence JC. Signal transduction and protein phosphorylation in the regulation of cellular metabolism by insulin. Annu Rev Physiol. 54:1992;177-193.
    • (1992) Annu Rev Physiol , vol.54 , pp. 177-193
    • Lawrence, J.C.1
  • 39
    • 0020585165 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle: Effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo
    • Parker PJ, Caudwell FB, Cohen P. Glycogen synthase from rabbit skeletal muscle: effect of insulin on the state of phosphorylation of the seven phosphoserine residues in vivo. Eur J Biochem. 130:1983;297-303.
    • (1983) Eur J Biochem , vol.130 , pp. 297-303
    • Parker, P.J.1    Caudwell, F.B.2    Cohen, P.3
  • 40
    • 0019025978 scopus 로고
    • Glycogen synthase from rabbit skeletal muscle: Amino acid sequence of the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase
    • Rylatt DB, Aitken A, Bilham T, Condon GD, Embi N, Cohen P. Glycogen synthase from rabbit skeletal muscle: amino acid sequence of the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase. Eur J Biochem. 107:1980;529-537.
    • (1980) Eur J Biochem , vol.107 , pp. 529-537
    • Rylatt, D.B.1    Aitken, A.2    Bilham, T.3    Condon, G.D.4    Embi, N.5    Cohen, P.6
  • 41
    • 0021840722 scopus 로고
    • The protein phosphatases involved in cellular regulation. Purification and characterisation of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle
    • Strälfors P, Hiraga A, Cohen P. The protein phosphatases involved in cellular regulation. Purification and characterisation of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle. Eur J Biochem. 149:1985;295-303.
    • (1985) Eur J Biochem , vol.149 , pp. 295-303
    • Strälfors, P.1    Hiraga, A.2    Cohen, P.3
  • 42
    • 0024811049 scopus 로고
    • Regulation of protein phosphatase-1G from rabbit skeletal muscle
    • Hubbard MJ, Cohen P. Regulation of protein phosphatase-1G from rabbit skeletal muscle. Eur J Biochem. 186:1989;711-716.
    • (1989) Eur J Biochem , vol.186 , pp. 711-716
    • Hubbard, M.J.1    Cohen, P.2
  • 43
    • 0028797745 scopus 로고
    • Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: Evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase
    • Shepherd PR, Nave BT, Siddle K. Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase. Biochem J. 309:1995;25-28.
    • (1995) Biochem J , vol.309 , pp. 25-28
    • Shepherd, P.R.1    Nave, B.T.2    Siddle, K.3
  • 44
    • 0026718508 scopus 로고
    • Mechanism of the regulation of eukaryotic protein synthesis
    • Merrick WC. Mechanism of the regulation of eukaryotic protein synthesis. Micro Biol Rev. 56:1992;291-315.
    • (1992) Micro Biol Rev , vol.56 , pp. 291-315
    • Merrick, W.C.1
  • 45
    • 0028271504 scopus 로고
    • Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation
    • Shantz LM, Pegg AE. Overproduction of ornithine decarboxylase caused by relief of translational repression is associated with neoplastic transformation. Cancer Res. 54:1994;2313-2316.
    • (1994) Cancer Res , vol.54 , pp. 2313-2316
    • Shantz, L.M.1    Pegg, A.E.2
  • 46
    • 0028034233 scopus 로고
    • Insulin dependent stimulation of protein synthesis by the phosphorylation of a regulator of 5′-cap function
    • Pause A, Belsham GJ, Gingras A-C, Donzé O, Lin TA, Lawrence JC, Sonenberg N. Insulin dependent stimulation of protein synthesis by the phosphorylation of a regulator of 5′-cap function. Nature. 371:1994;762-767.
    • (1994) Nature , vol.371 , pp. 762-767
    • Pause, A.1    Belsham, G.J.2    Gingras A-C3    Donzé, O.4    Lin, T.A.5    Lawrence, J.C.6    Sonenberg, N.7
  • 47
    • 0030013407 scopus 로고    scopus 로고
    • Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat cells
    • Diggle TA, Moule SK, Avison MB, Flynn A, Foulston EJ, Proud CG, Denton RM. Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat cells. Biochem J. 316:1996;447-453.
    • (1996) Biochem J , vol.316 , pp. 447-453
    • Diggle, T.A.1    Moule, S.K.2    Avison, M.B.3    Flynn, A.4    Foulston, E.J.5    Proud, C.G.6    Denton, R.M.7
  • 48
    • 0027936088 scopus 로고
    • Phosphorylation of PHAS-I by MAP-kinase. Identification of the site phosphorylated by MAP-kinase in vitro and in response to insulin in rat adipocytes
    • Haystead TAJ, Haystead CMM, Hu C, Lin TA, Lawrence JC. Phosphorylation of PHAS-I by MAP-kinase. Identification of the site phosphorylated by MAP-kinase in vitro and in response to insulin in rat adipocytes. J Biol Chem. 269:1994;23185-23191.
    • (1994) J Biol Chem , vol.269 , pp. 23185-23191
    • Haystead, T.A.J.1    Haystead, C.M.M.2    Hu, C.3    Lin, T.A.4    Lawrence, J.C.5
  • 50
    • 0029864854 scopus 로고    scopus 로고
    • Insulin and phorbol ester stimulate initiation factor eIF-4E phosphorylation by distinct mechanisms in Chinese hamster ovary cells overexpressing the insulin receptor
    • Flynn A, Proud CG. Insulin and phorbol ester stimulate initiation factor eIF-4E phosphorylation by distinct mechanisms in Chinese hamster ovary cells overexpressing the insulin receptor. Eur J Biochem. 236:1996;40-47.
    • (1996) Eur J Biochem , vol.236 , pp. 40-47
    • Flynn, A.1    Proud, C.G.2
  • 51
    • 0029966106 scopus 로고    scopus 로고
    • Regulation of translation elongation factor-2 by insulin via a rapamycin sensitive signaling pathway
    • Redpath NT, Foulstone EJ, Proud CG. Regulation of translation elongation factor-2 by insulin via a rapamycin sensitive signaling pathway. EMBO J. 15:1996;2291-2297.
    • (1996) EMBO J , vol.15 , pp. 2291-2297
    • Redpath, N.T.1    Foulstone, E.J.2    Proud, C.G.3
  • 52
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth dependent activation of and signaling by the 70kD S6 protein kinases
    • Chung J, Kuo CJ, Crabtree GR, Blenis J. Rapamycin-FKBP specifically blocks growth dependent activation of and signaling by the 70kD S6 protein kinases. Cell. 69:1992;1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 53
    • 0026759874 scopus 로고
    • Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
    • Price DJ, Grove JR, Calvo V, Avruch J, Bierer BE. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 257:1992;973-977.
    • (1992) Science , vol.257 , pp. 973-977
    • Price, D.J.1    Grove, J.R.2    Calvo, V.3    Avruch, J.4    Bierer, B.E.5
  • 54
    • 0028207001 scopus 로고
    • Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
    • Jefferies HBJ, Reinhard C, Kozma SC, Thomas G. Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc Natl Acad Sci USA. 91:1994;4441-4445.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4441-4445
    • Jefferies, H.B.J.1    Reinhard, C.2    Kozma, S.C.3    Thomas, G.4
  • 55
    • 0027277098 scopus 로고
    • On target with a new mechanism for the regulation of protein phosphorylation
    • Hubbard MJ, Cohen P. On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem Sci. 18:1993;172-177.
    • (1993) Trends Biochem Sci , vol.18 , pp. 172-177
    • Hubbard, M.J.1    Cohen, P.2
  • 56
    • 0028018097 scopus 로고
    • Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes - Studies using the selective inhibitor wortmannin
    • Rahn T, Ridderstråle M, Tornquist H, Manganiello V, Fredrickson G, Belfrage P, Degerman E. Essential role of phosphatidylinositol 3-kinase in insulin-induced activation and phosphorylation of the cGMP-inhibited cAMP phosphodiesterase in rat adipocytes - studies using the selective inhibitor wortmannin. FEBS Lett. 350:1994;314-318.
    • (1994) FEBS Lett , vol.350 , pp. 314-318
    • Rahn, T.1    Ridderstråle, M.2    Tornquist, H.3    Manganiello, V.4    Fredrickson, G.5    Belfrage, P.6    Degerman, E.7
  • 57
    • 0029989622 scopus 로고    scopus 로고
    • Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle
    • Kimball SR, Jefferson LS, Fadden P, Haystead TAJ, Lawrence JC. Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle. Am J Physiol. 39:1996;C705-C709.
    • (1996) Am J Physiol , vol.39
    • Kimball, S.R.1    Jefferson, L.S.2    Fadden, P.3    Haystead, T.A.J.4    Lawrence, J.C.5
  • 58
    • 0030442915 scopus 로고    scopus 로고
    • Insulin action in cultured human myoblasts: Contribution of different signaling pathways to the regulation of glycogen synthesis
    • Hurel SJ, Rochford JJ, Borthwick AC, Wells AM, Vandenheede JR, Turnbull DM, Yeaman SJ. Insulin action in cultured human myoblasts: contribution of different signaling pathways to the regulation of glycogen synthesis. Biochem J. 320:1996;871-877.
    • (1996) Biochem J , vol.320 , pp. 871-877
    • Hurel, S.J.1    Rochford, J.J.2    Borthwick, A.C.3    Wells, A.M.4    Vandenheede, J.R.5    Turnbull, D.M.6    Yeaman, S.J.7
  • 59
    • 0029808270 scopus 로고    scopus 로고
    • Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin
    • Lefebvre V, Méchin M-C, Louckx MP, Rider MH, Hue L. Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin. J Biol Chem. 271:1996;22289-22292.
    • (1996) J Biol Chem , vol.271 , pp. 22289-22292
    • Lefebvre, V.1    Méchin M-C2    Louckx, M.P.3    Rider, M.H.4    Hue, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.